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The map label for this gene is oxlT [H]

Identifier: 73538482

GI number: 73538482

Start: 1346369

End: 1347700

Strand: Reverse

Name: oxlT [H]

Synonym: Reut_B4656

Alternate gene names: 73538482

Gene position: 1347700-1346369 (Counterclockwise)

Preceding gene: 73538486

Following gene: 73538481

Centisome position: 49.44

GC content: 63.89

Gene sequence:

>1332_bases
ATGGCGCAACATCAAGCGGCAGCCGTGTCCGGCAATGGACGCGGCGTGCAGAATCGTTGGTTTCAGTTGGCCGTAGGCGT
GGTTTGCATGGGTTTGGTTGCAAACCTGCAGTATGGCTGGACCCTCTTCGTGTCACCGATGGACGCCAAGCATCACTGGG
GCACGTCCGCAATCCAGGTGGCGTTTTCGATTTTTATTGTGACCGAAACCTGGCTGGTGCCGCTTGAGGGCTGGCTGGTG
GACAAGTTCGGCCCGCGGCCGGTTGTGGCAGGTGGCGCGATCTGCGCGGGCCTTGCTTGGGTGATGAACGCGTATGCGAC
CACGCTGCCGGAGCTGTATGCGGCCGCGGTGATCGCGGGCATCGGCGCCGGTGGCGTGTATGGCACCTGCGTAGGCAATG
CGCTGAAGTGGTTCCCGGACAAGCGCGGCCTGGCGGCTGGCCTGACGGCGGCAGGCTTTGGCGCGGGCTCCGCAATCACG
GTGATTCCCATCGCGAACATGATCCAGAGCTCGGGCTATGAGCACGCCTTCCTGTTCTTCGGCATCCTGCAAGGCGTGGC
GATCTTCGCACTGTCGTTGCTGCTGGTGAAGCCGCGTGCACCGAAGGGCGCGGTGGCAGCCAAGGCGGTGCTGACGAACC
CGGTCGAGTTCACGCCTGGCCAGATGGTGAAGACGCCGGTGTTCTGGCTGATCTACGCGAGCTTCGTCGCAGTCGCTGCC
GGCGGCATCATGGCCACGGCGCAGCTTGGCCCGATCGCCAAGGACTTCGGCTTCGCCTCGATGCCGGTGACGATGCTCGG
TATGACGCTGCCGCTGCTGACGATGACGCTGTCGATCGACAACCTGTGCAACGGCTTCACGCGTCCTCTCTGTGGTTTCC
TGTCTGACCGCTTCGGCCGCGAGAACACGATGTTCGTGATCTTCATCGGCGAAGGCCTGGCGCTGTTGGGTCTGATGAAG
TTCGGCCACGACCCGTACGCCTTCATGTTCTTCGCGGCGCTCACGTTCCTGTTCTGGGGCGAGATCTTCTCGATCTTCCC
GGCACTGTGCGCAGACACGTTTGGCAGCAAGTTTGCTGCAGCGAATGCGGGCACGCTGTACACGGCAAAGGGCACGGCCG
CGATGCTGGTACCGCTGGCGTCGATCCTGTCCGCACGTGGCGGCTGGGATGCGGTGTTCACGGTGGCGGCAGTGGTGACG
ATCGCGGCCGGGCTGTCGGCGAAGGTGGTGCTTGCGCCGATGCGCAGGCGGTTCATCACGGGCCATGCCGAGGCCGCCGT
GCCGGTGTCGGATGCCGCGTTCATGGTACGCACCCATAGGGAAGCCGAATAA

Upstream 100 bases:

>100_bases
CAATGTCAGGCGCCGATCTAGTCGTTTAGGGCCCGCCCCACAGAGGCCCAGGAAAGCGTCCCGTCGGGGACGCATCAGAA
CCGCACTAGGAGACAGTTAG

Downstream 100 bases:

>100_bases
ACAGGAAGCAGGGAAGGACTGGGGGGGCCGGCTGCATCCGGACCCCAACGCCCCCGGCAAGCGGTCTGCGCACGGCGCAG
GCCGCTTGGCATGTGGGCCA

Product: major facilitator transporter

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MAQHQAAAVSGNGRGVQNRWFQLAVGVVCMGLVANLQYGWTLFVSPMDAKHHWGTSAIQVAFSIFIVTETWLVPLEGWLV
DKFGPRPVVAGGAICAGLAWVMNAYATTLPELYAAAVIAGIGAGGVYGTCVGNALKWFPDKRGLAAGLTAAGFGAGSAIT
VIPIANMIQSSGYEHAFLFFGILQGVAIFALSLLLVKPRAPKGAVAAKAVLTNPVEFTPGQMVKTPVFWLIYASFVAVAA
GGIMATAQLGPIAKDFGFASMPVTMLGMTLPLLTMTLSIDNLCNGFTRPLCGFLSDRFGRENTMFVIFIGEGLALLGLMK
FGHDPYAFMFFAALTFLFWGEIFSIFPALCADTFGSKFAAANAGTLYTAKGTAAMLVPLASILSARGGWDAVFTVAAVVT
IAAGLSAKVVLAPMRRRFITGHAEAAVPVSDAAFMVRTHREAE

Sequences:

>Translated_443_residues
MAQHQAAAVSGNGRGVQNRWFQLAVGVVCMGLVANLQYGWTLFVSPMDAKHHWGTSAIQVAFSIFIVTETWLVPLEGWLV
DKFGPRPVVAGGAICAGLAWVMNAYATTLPELYAAAVIAGIGAGGVYGTCVGNALKWFPDKRGLAAGLTAAGFGAGSAIT
VIPIANMIQSSGYEHAFLFFGILQGVAIFALSLLLVKPRAPKGAVAAKAVLTNPVEFTPGQMVKTPVFWLIYASFVAVAA
GGIMATAQLGPIAKDFGFASMPVTMLGMTLPLLTMTLSIDNLCNGFTRPLCGFLSDRFGRENTMFVIFIGEGLALLGLMK
FGHDPYAFMFFAALTFLFWGEIFSIFPALCADTFGSKFAAANAGTLYTAKGTAAMLVPLASILSARGGWDAVFTVAAVVT
IAAGLSAKVVLAPMRRRFITGHAEAAVPVSDAAFMVRTHREAE
>Mature_442_residues
AQHQAAAVSGNGRGVQNRWFQLAVGVVCMGLVANLQYGWTLFVSPMDAKHHWGTSAIQVAFSIFIVTETWLVPLEGWLVD
KFGPRPVVAGGAICAGLAWVMNAYATTLPELYAAAVIAGIGAGGVYGTCVGNALKWFPDKRGLAAGLTAAGFGAGSAITV
IPIANMIQSSGYEHAFLFFGILQGVAIFALSLLLVKPRAPKGAVAAKAVLTNPVEFTPGQMVKTPVFWLIYASFVAVAAG
GIMATAQLGPIAKDFGFASMPVTMLGMTLPLLTMTLSIDNLCNGFTRPLCGFLSDRFGRENTMFVIFIGEGLALLGLMKF
GHDPYAFMFFAALTFLFWGEIFSIFPALCADTFGSKFAAANAGTLYTAKGTAAMLVPLASILSARGGWDAVFTVAAVVTI
AAGLSAKVVLAPMRRRFITGHAEAAVPVSDAAFMVRTHREAE

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Escherichia coli, GI1789969, Length=412, Percent_Identity=24.7572815533981, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46588; Mature: 46457

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQHQAAAVSGNGRGVQNRWFQLAVGVVCMGLVANLQYGWTLFVSPMDAKHHWGTSAIQV
CCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHH
AFSIFIVTETWLVPLEGWLVDKFGPRPVVAGGAICAGLAWVMNAYATTLPELYAAAVIAG
HHHHHEEEHHHEEECCCEEECCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGAGGVYGTCVGNALKWFPDKRGLAAGLTAAGFGAGSAITVIPIANMIQSSGYEHAFLFF
CCCCCHHHHHHHHHHHHCCCCCCCHHCCHHHCCCCCCEEEEHHHHHHHHCCCCCHHHHHH
GILQGVAIFALSLLLVKPRAPKGAVAAKAVLTNPVEFTPGQMVKTPVFWLIYASFVAVAA
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GGIMATAQLGPIAKDFGFASMPVTMLGMTLPLLTMTLSIDNLCNGFTRPLCGFLSDRFGR
CCCEEEHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ENTMFVIFIGEGLALLGLMKFGHDPYAFMFFAALTFLFWGEIFSIFPALCADTFGSKFAA
CCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ANAGTLYTAKGTAAMLVPLASILSARGGWDAVFTVAAVVTIAAGLSAKVVLAPMRRRFIT
CCCCEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
GHAEAAVPVSDAAFMVRTHREAE
CCCCCCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
AQHQAAAVSGNGRGVQNRWFQLAVGVVCMGLVANLQYGWTLFVSPMDAKHHWGTSAIQV
CCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHH
AFSIFIVTETWLVPLEGWLVDKFGPRPVVAGGAICAGLAWVMNAYATTLPELYAAAVIAG
HHHHHEEEHHHEEECCCEEECCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGAGGVYGTCVGNALKWFPDKRGLAAGLTAAGFGAGSAITVIPIANMIQSSGYEHAFLFF
CCCCCHHHHHHHHHHHHCCCCCCCHHCCHHHCCCCCCEEEEHHHHHHHHCCCCCHHHHHH
GILQGVAIFALSLLLVKPRAPKGAVAAKAVLTNPVEFTPGQMVKTPVFWLIYASFVAVAA
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GGIMATAQLGPIAKDFGFASMPVTMLGMTLPLLTMTLSIDNLCNGFTRPLCGFLSDRFGR
CCCEEEHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ENTMFVIFIGEGLALLGLMKFGHDPYAFMFFAALTFLFWGEIFSIFPALCADTFGSKFAA
CCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ANAGTLYTAKGTAAMLVPLASILSARGGWDAVFTVAAVVTIAAGLSAKVVLAPMRRRFIT
CCCCEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
GHAEAAVPVSDAAFMVRTHREAE
CCCCCCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]