| Definition | Ralstonia eutropha JMP134 chromosome chromosome 2, complete sequence. |
|---|---|
| Accession | NC_007348 |
| Length | 2,726,152 |
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The map label for this gene is fabG [C]
Identifier: 73538399
GI number: 73538399
Start: 1252087
End: 1252863
Strand: Reverse
Name: fabG [C]
Synonym: Reut_B4572
Alternate gene names: 73538399
Gene position: 1252863-1252087 (Counterclockwise)
Preceding gene: 73538401
Following gene: 73538398
Centisome position: 45.96
GC content: 64.86
Gene sequence:
>777_bases ATGCGGATGCAGGGCAAGATCGCGCTCGTTACCGGAGGTGCCTCCGGCATGGGTCTCGCCTTCACAAGGCGGCTGGCGCA AGAAGGCGCCCGGGTCTATTTCACGGACATTAACGGGGCTGCGGGGCACGCTACCGAAAGCGAACTGCAAGGCGCGGGCC TCGCGGTGGTTTTCCTGCGGCACGACGTCACGCAGGAAAACGACTGGCTGCGGGTGCTCGAACACATCGGCGCTGTCGAC GGCCGGCTCGACGTGCTCGTGAACAACGCCGGCATTGCCATCTCGCACAACATCGAGACCTGCACGACCGAGGATTTCGA CCGCACCCTCAACGTCAACCTGAAGAGCGTCTTCCTCGGCTGCAAGCATGGACTGGCCCTGATGAAGCAGAAGGGCGGAT CGATCATCAACGTGTCGTCGATTACGGCCATTTGCGGCGAGCCCGTGGCGCTGGCCTACAGCGCCTCCAAGGCGGGCGTG CGCTTCTTGTCCAAATCCGTCGCGCTGCACTGCGCGGAAAAGGGCTATGCGATCCGCGTCAACAGCCTCCATCCGGGCTA CATCGATACGCCGCTGCTTGCCGGCAGCAACGCCGGCGGCAGCCTGACCGCGGACGAGGTCACGGCGTCGCGCGTGCGCA TCGGCGGCGAGATTCCGCTGAAGCGCAGAGGCACGCCGGACGAGGTGGCTGGCGCCGTGCTCTATCTGGCCAGCGACGAG TCGACCTATGTCACCGGCACCGAACTGGTTATCGATGGCGGCTACGCCTGCCACTGA
Upstream 100 bases:
>100_bases TCGTGCCCACGCCCGCGCGTCGCCCAAGTGTCAGTCGCCTGATCGGCGCCGGCATCGTTCCGTGTGCCGCCCATGACCCT TCGATTCAACAGGATTCAAT
Downstream 100 bases:
>100_bases CCACTGTCCACTGTCCACTGACGGTTCTGCCTTCACCGACACCCATACAAGATCCCTGCAACAAAGGAAACCCGCACCCA TGACGCTCCCCGCCACCATC
Product: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 258; Mature: 258
Protein sequence:
>258_residues MRMQGKIALVTGGASGMGLAFTRRLAQEGARVYFTDINGAAGHATESELQGAGLAVVFLRHDVTQENDWLRVLEHIGAVD GRLDVLVNNAGIAISHNIETCTTEDFDRTLNVNLKSVFLGCKHGLALMKQKGGSIINVSSITAICGEPVALAYSASKAGV RFLSKSVALHCAEKGYAIRVNSLHPGYIDTPLLAGSNAGGSLTADEVTASRVRIGGEIPLKRRGTPDEVAGAVLYLASDE STYVTGTELVIDGGYACH
Sequences:
>Translated_258_residues MRMQGKIALVTGGASGMGLAFTRRLAQEGARVYFTDINGAAGHATESELQGAGLAVVFLRHDVTQENDWLRVLEHIGAVD GRLDVLVNNAGIAISHNIETCTTEDFDRTLNVNLKSVFLGCKHGLALMKQKGGSIINVSSITAICGEPVALAYSASKAGV RFLSKSVALHCAEKGYAIRVNSLHPGYIDTPLLAGSNAGGSLTADEVTASRVRIGGEIPLKRRGTPDEVAGAVLYLASDE STYVTGTELVIDGGYACH >Mature_258_residues MRMQGKIALVTGGASGMGLAFTRRLAQEGARVYFTDINGAAGHATESELQGAGLAVVFLRHDVTQENDWLRVLEHIGAVD GRLDVLVNNAGIAISHNIETCTTEDFDRTLNVNLKSVFLGCKHGLALMKQKGGSIINVSSITAICGEPVALAYSASKAGV RFLSKSVALHCAEKGYAIRVNSLHPGYIDTPLLAGSNAGGSLTADEVTASRVRIGGEIPLKRRGTPDEVAGAVLYLASDE STYVTGTELVIDGGYACH
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI59889578, Length=241, Percent_Identity=35.6846473029046, Blast_Score=119, Evalue=2e-27, Organism=Homo sapiens, GI66933014, Length=263, Percent_Identity=36.1216730038023, Blast_Score=115, Evalue=3e-26, Organism=Homo sapiens, GI15277342, Length=263, Percent_Identity=34.6007604562738, Blast_Score=114, Evalue=6e-26, Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=32.6771653543307, Blast_Score=114, Evalue=8e-26, Organism=Homo sapiens, GI40254992, Length=250, Percent_Identity=35.2, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI4758504, Length=265, Percent_Identity=35.0943396226415, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI19923817, Length=265, Percent_Identity=30.5660377358491, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI31542939, Length=203, Percent_Identity=34.4827586206897, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=32.6848249027237, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI83715985, Length=266, Percent_Identity=33.4586466165414, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI126723750, Length=257, Percent_Identity=28.0155642023346, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI224922801, Length=178, Percent_Identity=35.3932584269663, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI126723191, Length=200, Percent_Identity=32.5, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI7705925, Length=259, Percent_Identity=29.7297297297297, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=36.0824742268041, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI10190704, Length=264, Percent_Identity=29.1666666666667, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4504505, Length=247, Percent_Identity=30.3643724696356, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI109715829, Length=196, Percent_Identity=27.0408163265306, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI4503301, Length=256, Percent_Identity=27.734375, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI142976729, Length=207, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI1787335, Length=255, Percent_Identity=36.078431372549, Blast_Score=127, Evalue=9e-31, Organism=Escherichia coli, GI2367175, Length=255, Percent_Identity=35.2941176470588, Blast_Score=125, Evalue=2e-30, Organism=Escherichia coli, GI87082160, Length=260, Percent_Identity=33.4615384615385, Blast_Score=125, Evalue=3e-30, Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=34.1176470588235, Blast_Score=123, Evalue=1e-29, Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=30.46875, Blast_Score=114, Evalue=5e-27, Organism=Escherichia coli, GI1789208, Length=257, Percent_Identity=31.9066147859922, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=33.1983805668016, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI1788459, Length=258, Percent_Identity=31.3953488372093, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1786812, Length=260, Percent_Identity=31.1538461538462, Blast_Score=95, Evalue=4e-21, Organism=Escherichia coli, GI2367365, Length=255, Percent_Identity=30.9803921568627, Blast_Score=95, Evalue=5e-21, Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=32.4324324324324, Blast_Score=93, Evalue=1e-20, Organism=Escherichia coli, GI1787905, Length=255, Percent_Identity=30.1960784313725, Blast_Score=91, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=36.4705882352941, Blast_Score=125, Evalue=2e-29, Organism=Caenorhabditis elegans, GI25147288, Length=255, Percent_Identity=36.078431372549, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=33.4615384615385, Blast_Score=110, Evalue=6e-25, Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=31.5589353612167, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=33.5849056603774, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=31.1787072243346, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI17538182, Length=264, Percent_Identity=32.5757575757576, Blast_Score=101, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=31.1111111111111, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=29.8507462686567, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=31.0606060606061, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=30.8270676691729, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=30.8270676691729, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=31.496062992126, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17538486, Length=273, Percent_Identity=28.2051282051282, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=29.1338582677165, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=30.188679245283, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=30.9803921568627, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=27.9245283018868, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=28.3018867924528, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=29.5454545454545, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17560150, Length=269, Percent_Identity=28.996282527881, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=27.906976744186, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=26.7924528301887, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=29.2307692307692, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI193203117, Length=196, Percent_Identity=27.0408163265306, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=26.9372693726937, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI193203115, Length=194, Percent_Identity=27.319587628866, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17536025, Length=259, Percent_Identity=27.7992277992278, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=27.8195488721804, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17565030, Length=271, Percent_Identity=28.0442804428044, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17567345, Length=211, Percent_Identity=25.5924170616114, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17561272, Length=194, Percent_Identity=28.3505154639175, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17536651, Length=272, Percent_Identity=26.1029411764706, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17508651, Length=255, Percent_Identity=30.5882352941176, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17568967, Length=198, Percent_Identity=30.8080808080808, Blast_Score=68, Evalue=4e-12, Organism=Saccharomyces cerevisiae, GI6324126, Length=263, Percent_Identity=27.7566539923954, Blast_Score=74, Evalue=2e-14, Organism=Saccharomyces cerevisiae, GI6322861, Length=265, Percent_Identity=27.1698113207547, Blast_Score=71, Evalue=1e-13, Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=37.007874015748, Blast_Score=127, Evalue=6e-30, Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=35.7692307692308, Blast_Score=126, Evalue=1e-29, Organism=Drosophila melanogaster, GI28571526, Length=255, Percent_Identity=34.9019607843137, Blast_Score=122, Evalue=2e-28, Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=35.1778656126482, Blast_Score=120, Evalue=9e-28, Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=34.765625, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=34.765625, Blast_Score=118, Evalue=4e-27, Organism=Drosophila melanogaster, GI24643142, Length=255, Percent_Identity=34.5098039215686, Blast_Score=110, Evalue=1e-24, Organism=Drosophila melanogaster, GI17737361, Length=270, Percent_Identity=33.7037037037037, Blast_Score=104, Evalue=5e-23, Organism=Drosophila melanogaster, GI24644337, Length=175, Percent_Identity=36, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI18859837, Length=182, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI24649181, Length=196, Percent_Identity=29.0816326530612, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24665243, Length=198, Percent_Identity=28.7878787878788, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI221331218, Length=198, Percent_Identity=28.7878787878788, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI21355631, Length=167, Percent_Identity=26.9461077844311, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI281364892, Length=190, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI221331216, Length=199, Percent_Identity=28.643216080402, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24665247, Length=199, Percent_Identity=28.643216080402, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI28571387, Length=269, Percent_Identity=27.8810408921933, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.51 [H]
Molecular weight: Translated: 27084; Mature: 27084
Theoretical pI: Translated: 6.71; Mature: 6.71
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.9 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 1.9 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRMQGKIALVTGGASGMGLAFTRRLAQEGARVYFTDINGAAGHATESELQGAGLAVVFLR CCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHCCCCEEEEEEE HDVTQENDWLRVLEHIGAVDGRLDVLVNNAGIAISHNIETCTTEDFDRTLNVNLKSVFLG CCCCCCCHHHHHHHHCCCCCCEEEEEEECCCEEEECCCCCCCCCCCCCEECCCHHHEEEE CKHGLALMKQKGGSIINVSSITAICGEPVALAYSASKAGVRFLSKSVALHCAEKGYAIRV HHHCHHHHHHCCCCEEEEHHHHHHCCCCEEEEEECCHHHHHHHHHHHEEEECCCCEEEEE NSLHPGYIDTPLLAGSNAGGSLTADEVTASRVRIGGEIPLKRRGTPDEVAGAVLYLASDE CCCCCCCCCCCEEECCCCCCCEEHHHHEEEHEEECCCCCCCCCCCHHHHCEEEEEEECCC STYVTGTELVIDGGYACH CEEEECEEEEEECCEECC >Mature Secondary Structure MRMQGKIALVTGGASGMGLAFTRRLAQEGARVYFTDINGAAGHATESELQGAGLAVVFLR CCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHCCCCEEEEEEE HDVTQENDWLRVLEHIGAVDGRLDVLVNNAGIAISHNIETCTTEDFDRTLNVNLKSVFLG CCCCCCCHHHHHHHHCCCCCCEEEEEEECCCEEEECCCCCCCCCCCCCEECCCHHHEEEE CKHGLALMKQKGGSIINVSSITAICGEPVALAYSASKAGVRFLSKSVALHCAEKGYAIRV HHHCHHHHHHCCCCEEEEHHHHHHCCCCEEEEEECCHHHHHHHHHHHEEEECCCCEEEEE NSLHPGYIDTPLLAGSNAGGSLTADEVTASRVRIGGEIPLKRRGTPDEVAGAVLYLASDE CCCCCCCCCCCEEECCCCCCCEEHHHHEEEHEEECCCCCCCCCCCHHHHCEEEEEEECCC STYVTGTELVIDGGYACH CEEEECEEEEEECCEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8382516; 2026158; 8617258 [H]