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The map label for this gene is pkn1 [H]

Identifier: 73538395

GI number: 73538395

Start: 1247527

End: 1248699

Strand: Reverse

Name: pkn1 [H]

Synonym: Reut_B4568

Alternate gene names: 73538395

Gene position: 1248699-1247527 (Counterclockwise)

Preceding gene: 73538396

Following gene: 73538394

Centisome position: 45.8

GC content: 68.8

Gene sequence:

>1173_bases
GTGATCCAGCGCAGAACAGCGACGCGGGCGCTTCTCGTGATCCTGGCGGGCAGCGCGGTTGCGGTCGCGACTGGCTATGC
CCGCTGGGGCGTGAGTGGGACCACGCGACCCGCGGCGGCGCCTGCCATCACGATTGGCGACGGTGTGAACGGGCCCGCCG
GGATGGCGCACATTCCCGGCGGCGAATTCCTGATGGGCAGCGACAGCAACATGGCGCAGCCCAATGAGAAGCCCGCGCAC
AAGGTGCGGGTGCACGGGTTCTGGATGGACCGCCATCACGTCACCAATGCCCAGTTCCGGGATTTCGTGAAGGCAACTGG
CTATGTCACGACCGCCGAACGCAAGCCCGAGTGGGAAACCCTGAGGGTCCAACTGCCCGCTGGCACGCCGCGACCGCCCG
ACAGTGCGCTGGTGCCGGGCGGCATGGTCTTCGTTGGCACGTCACGTCCGGTGCCGCTGAAAGACTACTCGCAGTGGTGG
CGCTACGTACCGGGGGCCGACTGGCGCCATCCGGGCGGGCCCGGCACGTCGATCGACGGCAAGGATGACCATCCGGTTGT
CCAGGTGTCGTATGAAGACGCGCAGGCGTATGCACGGTGGGTTGGCAAGCGTCTGCCGACAGAGGCCGAATGGGAGTTCG
CCGCCCGTGGCGGGCTGGAGCAGGCGACCTATGCCTGGGGCGGGACGTTCGCGCCGGAAGGCCGGCAGATGGCCAACGTC
TGGCAGGGACAGCAGGCACAGCCTTTCCCGGTCGCCAGCCCCAAGGCGGGCGGCGCGCTGGGCACCAGCCCGGTCGGCAC
CTTCCCCGAGAACGGCTACGGACTCTATGACATGACCGGAAACGCCTGGCAGTGGGTTGCCGACTGGTATCGGGCCGACC
AGTTCCGGCAAGAAGCCGCCGCCGGCCGGCGCGTTGACGACCCGAAGGGGCCCGTCTCTTCCTGGGACCCGGACGATGCC
GGCGTGCCCACCGATGCGCCCAAGCGTGTCACGCGCGGTGGCTCGTTCCTGTGCAACGAGGACTATTGCCTCAGCTACCG
CCCCAGCGCGCGGCGGGGCACGGACCCGTACAACAGCATGTCGCACCTCGGCTTCCGTCTGGTCATGGACGACAGCCGCT
GGGCGGCAACACGCGGCCAGGCGGACCGCGCGAAGGACAGCATGGCTCGATAG

Upstream 100 bases:

>100_bases
CAAGTCGTTCGACCGTTCAAACATGGTCCAGGACTTTCTGCAGCAGCAACAGCAGTTGCGGCAGCGGCAGCAGCAACAGG
CGGCGATCAGGGAGTAAGGC

Downstream 100 bases:

>100_bases
CAAGGAGAAGCCATCGTGAGGGAACGTCCCAGGTTCGCGTGCATGTAGGACAACACCCGCGCCGCAACGAAAACAAATCC
ATACACAACGGAGGAGACAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MIQRRTATRALLVILAGSAVAVATGYARWGVSGTTRPAAAPAITIGDGVNGPAGMAHIPGGEFLMGSDSNMAQPNEKPAH
KVRVHGFWMDRHHVTNAQFRDFVKATGYVTTAERKPEWETLRVQLPAGTPRPPDSALVPGGMVFVGTSRPVPLKDYSQWW
RYVPGADWRHPGGPGTSIDGKDDHPVVQVSYEDAQAYARWVGKRLPTEAEWEFAARGGLEQATYAWGGTFAPEGRQMANV
WQGQQAQPFPVASPKAGGALGTSPVGTFPENGYGLYDMTGNAWQWVADWYRADQFRQEAAAGRRVDDPKGPVSSWDPDDA
GVPTDAPKRVTRGGSFLCNEDYCLSYRPSARRGTDPYNSMSHLGFRLVMDDSRWAATRGQADRAKDSMAR

Sequences:

>Translated_390_residues
MIQRRTATRALLVILAGSAVAVATGYARWGVSGTTRPAAAPAITIGDGVNGPAGMAHIPGGEFLMGSDSNMAQPNEKPAH
KVRVHGFWMDRHHVTNAQFRDFVKATGYVTTAERKPEWETLRVQLPAGTPRPPDSALVPGGMVFVGTSRPVPLKDYSQWW
RYVPGADWRHPGGPGTSIDGKDDHPVVQVSYEDAQAYARWVGKRLPTEAEWEFAARGGLEQATYAWGGTFAPEGRQMANV
WQGQQAQPFPVASPKAGGALGTSPVGTFPENGYGLYDMTGNAWQWVADWYRADQFRQEAAAGRRVDDPKGPVSSWDPDDA
GVPTDAPKRVTRGGSFLCNEDYCLSYRPSARRGTDPYNSMSHLGFRLVMDDSRWAATRGQADRAKDSMAR
>Mature_390_residues
MIQRRTATRALLVILAGSAVAVATGYARWGVSGTTRPAAAPAITIGDGVNGPAGMAHIPGGEFLMGSDSNMAQPNEKPAH
KVRVHGFWMDRHHVTNAQFRDFVKATGYVTTAERKPEWETLRVQLPAGTPRPPDSALVPGGMVFVGTSRPVPLKDYSQWW
RYVPGADWRHPGGPGTSIDGKDDHPVVQVSYEDAQAYARWVGKRLPTEAEWEFAARGGLEQATYAWGGTFAPEGRQMANV
WQGQQAQPFPVASPKAGGALGTSPVGTFPENGYGLYDMTGNAWQWVADWYRADQFRQEAAAGRRVDDPKGPVSSWDPDDA
GVPTDAPKRVTRGGSFLCNEDYCLSYRPSARRGTDPYNSMSHLGFRLVMDDSRWAATRGQADRAKDSMAR

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=337, Percent_Identity=39.1691394658754, Blast_Score=234, Evalue=7e-62,
Organism=Homo sapiens, GI257470975, Length=337, Percent_Identity=37.9821958456973, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI257470977, Length=337, Percent_Identity=35.9050445103858, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI194248088, Length=334, Percent_Identity=35.0299401197605, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI194248087, Length=334, Percent_Identity=32.9341317365269, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI194248090, Length=227, Percent_Identity=40.5286343612335, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI226437577, Length=218, Percent_Identity=38.9908256880734, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI20130397, Length=316, Percent_Identity=34.8101265822785, Blast_Score=191, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 42492; Mature: 42492

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQRRTATRALLVILAGSAVAVATGYARWGVSGTTRPAAAPAITIGDGVNGPAGMAHIPG
CCCCHHHHHEEEEEECCCHHEEEECHHHCCCCCCCCCCCCCEEEECCCCCCCCCEEECCC
GEFLMGSDSNMAQPNEKPAHKVRVHGFWMDRHHVTNAQFRDFVKATGYVTTAERKPEWET
CCEEECCCCCCCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHCCEEEECCCCCCCEE
LRVQLPAGTPRPPDSALVPGGMVFVGTSRPVPLKDYSQWWRYVPGADWRHPGGPGTSIDG
EEEECCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
KDDHPVVQVSYEDAQAYARWVGKRLPTEAEWEFAARGGLEQATYAWGGTFAPEGRQMANV
CCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHEEECCCCCCCCCCHHHHH
WQGQQAQPFPVASPKAGGALGTSPVGTFPENGYGLYDMTGNAWQWVADWYRADQFRQEAA
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
AGRRVDDPKGPVSSWDPDDAGVPTDAPKRVTRGGSFLCNEDYCLSYRPSARRGTDPYNSM
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEECCCCEEEECCCCCCCCCCHHHH
SHLGFRLVMDDSRWAATRGQADRAKDSMAR
HHCEEEEEEECCCHHHCCCCHHHHHHHHCC
>Mature Secondary Structure
MIQRRTATRALLVILAGSAVAVATGYARWGVSGTTRPAAAPAITIGDGVNGPAGMAHIPG
CCCCHHHHHEEEEEECCCHHEEEECHHHCCCCCCCCCCCCCEEEECCCCCCCCCEEECCC
GEFLMGSDSNMAQPNEKPAHKVRVHGFWMDRHHVTNAQFRDFVKATGYVTTAERKPEWET
CCEEECCCCCCCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHCCEEEECCCCCCCEE
LRVQLPAGTPRPPDSALVPGGMVFVGTSRPVPLKDYSQWWRYVPGADWRHPGGPGTSIDG
EEEECCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
KDDHPVVQVSYEDAQAYARWVGKRLPTEAEWEFAARGGLEQATYAWGGTFAPEGRQMANV
CCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHEEECCCCCCCCCCHHHHH
WQGQQAQPFPVASPKAGGALGTSPVGTFPENGYGLYDMTGNAWQWVADWYRADQFRQEAA
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
AGRRVDDPKGPVSSWDPDDAGVPTDAPKRVTRGGSFLCNEDYCLSYRPSARRGTDPYNSM
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEECCCCEEEECCCCCCCCCCHHHH
SHLGFRLVMDDSRWAATRGQADRAKDSMAR
HHCEEEEEEECCCHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]