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The map label for this gene is acdA [H]

Identifier: 73538385

GI number: 73538385

Start: 1236509

End: 1237591

Strand: Reverse

Name: acdA [H]

Synonym: Reut_B4558

Alternate gene names: 73538385

Gene position: 1237591-1236509 (Counterclockwise)

Preceding gene: 73538386

Following gene: 73538384

Centisome position: 45.4

GC content: 67.96

Gene sequence:

>1083_bases
ATGAATCTCCAATGGAACGATGTCCAGCAGCAACTGAAAGACAGCCTGTCCCGGCTGCTGGCGAATGAATACGACTTCGA
ACACCGGCAACGCTACGTGGCCGCGGCGGAAGGGCACGCGCCCGCGGTCTGGGCGAAGCTGACCGAACTTGGTGTGCCTG
CTGCCGCGATTCCCGAAGCATGGGGCGGCTTTGGCGGCGATGCCGTGGACCACATGATGGTCTCGGAGGCGCTTGGCCGA
CACTTGTCCCTGGAGCCGTACCACGGCACCGCGGTCATGGGCGCGACTGCCATCGCGCTGGCGGGCAGCGACGCGCAGAA
GGCTGCCTTGCTGCCGCGCATCGCGGATGGCACCGTTCAGGTGGCGTGGGCGCATGACGAGGCGGTGGCGGGGCGCGTCA
CCGTCCAAGCGGGTGGTGGCACGCTGACCGGCGCCAAGCCGTGCGTGCTGCATGGCGCATCGGCCGATTACCTGCTGGTG
ACGGCGAGAGTCGGCGACGGTGTCGGTCTCTTCCTCCTCGATGGCCGCGCTAGCGGCGTGCGCCGCGACGGCTACCGCCT
GATCGACGGCACGCCGGTGGCGGATGTCCATCTCGATGGGGCAGTGGCCGAGCCGCTGCCCGGTGCGAACGCGGAGATCC
TGTCCCGCATCCTGGCCATCGGTATCAACGCGGCCTGCGCCGAAATGGTTGGCGCGATGGATGCCGCCGTCGCACTCACT
GTCGAGTACCTGAAGACCCGCAAGCAGTTCGGCAAGTTCATCGGCTCGAACCAGGCGCTGCAGCATCGCGCGGTGGACAT
GCTCACGGCGCTGGAGCAGAGCCGCAGCCTGTCGCTCTCGCTGGCGCTCGCCTTGGCCGGGCGCAACGACCTGGCCGGCG
GCGATATGCAGGCGCACGCGGCCAAGGCGTATATCGGCCAGGCAGCGCGGCAGGTTACGCAGGAAGCCATTCAGATGCAC
GGCGGCATCGGCATGACCGAGGAGTACGCGGTGGGCCACTACCTGCGCCGCGTGCTCGTGTTCGACCGGCTGCACGGCGA
TATCCACTACCACACCCGCCGCCTCGAAGGCTGGCAGGACTGA

Upstream 100 bases:

>100_bases
CGCTGACCAAGTCATACCTGTACTCGCGCGCCGTATCAATCTTCGGCGGCAGTACCGAGGTGCAGAAGAACATCCTGTCG
GCCACCGTGCTGAGCCTGCC

Downstream 100 bases:

>100_bases
CGCTACACATTGCAAGCCTTCCCACATCGTCACGCGGGAAGGGAAGCCACTACGACCAAGGAGACCTTCAATGTCCGAAA
TCATGTCCCTCAAGGGGAAA

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MNLQWNDVQQQLKDSLSRLLANEYDFEHRQRYVAAAEGHAPAVWAKLTELGVPAAAIPEAWGGFGGDAVDHMMVSEALGR
HLSLEPYHGTAVMGATAIALAGSDAQKAALLPRIADGTVQVAWAHDEAVAGRVTVQAGGGTLTGAKPCVLHGASADYLLV
TARVGDGVGLFLLDGRASGVRRDGYRLIDGTPVADVHLDGAVAEPLPGANAEILSRILAIGINAACAEMVGAMDAAVALT
VEYLKTRKQFGKFIGSNQALQHRAVDMLTALEQSRSLSLSLALALAGRNDLAGGDMQAHAAKAYIGQAARQVTQEAIQMH
GGIGMTEEYAVGHYLRRVLVFDRLHGDIHYHTRRLEGWQD

Sequences:

>Translated_360_residues
MNLQWNDVQQQLKDSLSRLLANEYDFEHRQRYVAAAEGHAPAVWAKLTELGVPAAAIPEAWGGFGGDAVDHMMVSEALGR
HLSLEPYHGTAVMGATAIALAGSDAQKAALLPRIADGTVQVAWAHDEAVAGRVTVQAGGGTLTGAKPCVLHGASADYLLV
TARVGDGVGLFLLDGRASGVRRDGYRLIDGTPVADVHLDGAVAEPLPGANAEILSRILAIGINAACAEMVGAMDAAVALT
VEYLKTRKQFGKFIGSNQALQHRAVDMLTALEQSRSLSLSLALALAGRNDLAGGDMQAHAAKAYIGQAARQVTQEAIQMH
GGIGMTEEYAVGHYLRRVLVFDRLHGDIHYHTRRLEGWQD
>Mature_360_residues
MNLQWNDVQQQLKDSLSRLLANEYDFEHRQRYVAAAEGHAPAVWAKLTELGVPAAAIPEAWGGFGGDAVDHMMVSEALGR
HLSLEPYHGTAVMGATAIALAGSDAQKAALLPRIADGTVQVAWAHDEAVAGRVTVQAGGGTLTGAKPCVLHGASADYLLV
TARVGDGVGLFLLDGRASGVRRDGYRLIDGTPVADVHLDGAVAEPLPGANAEILSRILAIGINAACAEMVGAMDAAVALT
VEYLKTRKQFGKFIGSNQALQHRAVDMLTALEQSRSLSLSLALALAGRNDLAGGDMQAHAAKAYIGQAARQVTQEAIQMH
GGIGMTEEYAVGHYLRRVLVFDRLHGDIHYHTRRLEGWQD

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI76496475, Length=402, Percent_Identity=24.6268656716418, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4557235, Length=402, Percent_Identity=24.6268656716418, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI21361497, Length=348, Percent_Identity=25.5747126436782, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4501859, Length=310, Percent_Identity=29.6774193548387, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI226958412, Length=375, Percent_Identity=25.3333333333333, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI226958414, Length=348, Percent_Identity=26.4367816091954, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI7656849, Length=357, Percent_Identity=26.3305322128852, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI4557231, Length=375, Percent_Identity=25.3333333333333, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI187960098, Length=375, Percent_Identity=25.3333333333333, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71985184, Length=339, Percent_Identity=28.023598820059, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17570075, Length=382, Percent_Identity=24.0837696335079, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17508101, Length=315, Percent_Identity=25.0793650793651, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17506239, Length=343, Percent_Identity=23.9067055393586, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17534899, Length=379, Percent_Identity=23.7467018469657, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71985192, Length=273, Percent_Identity=27.8388278388278, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17569725, Length=332, Percent_Identity=24.6987951807229, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 38176; Mature: 38176

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLQWNDVQQQLKDSLSRLLANEYDFEHRQRYVAAAEGHAPAVWAKLTELGVPAAAIPEA
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHCCHH
WGGFGGDAVDHMMVSEALGRHLSLEPYHGTAVMGATAIALAGSDAQKAALLPRIADGTVQ
HCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHEEEEECCCHHHHHHCCEECCCEEE
VAWAHDEAVAGRVTVQAGGGTLTGAKPCVLHGASADYLLVTARVGDGVGLFLLDGRASGV
EEEECCCCCCCEEEEEECCCCCCCCCCEEEECCCCCEEEEEEEECCCEEEEEECCCCCCC
RRDGYRLIDGTPVADVHLDGAVAEPLPGANAEILSRILAIGINAACAEMVGAMDAAVALT
CCCCEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VEYLKTRKQFGKFIGSNQALQHRAVDMLTALEQSRSLSLSLALALAGRNDLAGGDMQAHA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCHHHHH
AKAYIGQAARQVTQEAIQMHGGIGMTEEYAVGHYLRRVLVFDRLHGDIHYHTRRLEGWQD
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCC
>Mature Secondary Structure
MNLQWNDVQQQLKDSLSRLLANEYDFEHRQRYVAAAEGHAPAVWAKLTELGVPAAAIPEA
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHCCHH
WGGFGGDAVDHMMVSEALGRHLSLEPYHGTAVMGATAIALAGSDAQKAALLPRIADGTVQ
HCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHEEEEECCCHHHHHHCCEECCCEEE
VAWAHDEAVAGRVTVQAGGGTLTGAKPCVLHGASADYLLVTARVGDGVGLFLLDGRASGV
EEEECCCCCCCEEEEEECCCCCCCCCCEEEECCCCCEEEEEEEECCCEEEEEECCCCCCC
RRDGYRLIDGTPVADVHLDGAVAEPLPGANAEILSRILAIGINAACAEMVGAMDAAVALT
CCCCEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VEYLKTRKQFGKFIGSNQALQHRAVDMLTALEQSRSLSLSLALALAGRNDLAGGDMQAHA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCHHHHH
AKAYIGQAARQVTQEAIQMHGGIGMTEEYAVGHYLRRVLVFDRLHGDIHYHTRRLEGWQD
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]