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The map label for this gene is 73538372

Identifier: 73538372

GI number: 73538372

Start: 1221825

End: 1223231

Strand: Direct

Name: 73538372

Synonym: Reut_B4545

Alternate gene names: NA

Gene position: 1221825-1223231 (Clockwise)

Preceding gene: 73538371

Following gene: 73538373

Centisome position: 44.82

GC content: 69.44

Gene sequence:

>1407_bases
ATGAACGACCTGATCATGTCGAATCCCGCAGATCTGTCCGCCACCGCATTGCTGGCGCTTTACGCCCGGCGCGACCTGTC
GCCAGTCGAGACGCTCGACGCCATCCTGCATCGCGTGGCCGAACGCGATCCTGCCTGCAATGCGTTCCGATTCATCGATG
CAGACGGCGCGCGCGAACAGGCGCGCGCGTCGGAACGACGCTGGCGGCGCGGTAAGCCGTGCGGCTTGCTGGACGGCGTG
CCGGTGTCGTTCAAGGACCTGCTCCACGTGCGCGGCTGGCCAACGCGTCTGGGCAGCCTTGCCACTACCGATACGCCGCA
GCCCGACGATTGCCCGGCCGCAGCGCGCCTGCGCGAGCACGGCGCCGTGCTGCTGGGCAAGACCAATACTTCGGAGTTCG
GCACGAAGGGCATCACCGAAAGCGCGCTGGCCGGCATCACGCGCAATCCCTGGAATACGACGCACACACCGGGCGGCAGC
AGCGGCGGCGCGGCCGCCGCCACCGCGCTCGGGCTGGGGCCATTGCATGTCGCGACCGACGGCGGTGGTTCCATCCGCGC
GCCATCGGCAGCCTGTGGCGTGTTTGGATTCAAGCCGGGCAGCGGACGCGTGCCCTGCTATCCGCCCGCGCATTCCGGCA
CGCTGTTCCACGTAGGGCCGATGGCGCGCACCGTCACGGACGCCGCACTGCTGCTCACCGCGATCAGCGGCCCCGACAGC
CGCGACTGGCACGCATTGCCTTATGAGGATCGCGACTGGCGCACCGGCCTCGACGATGGCATCGCAGGCCTGCGCGTCGC
CTACAGCCGCACCCTTGGCTACCTTCCCGTCGATCCCGAGGTAAGCGCATTGTGCGATGCCGCCGTCCGGCGCCTGATGG
CGCTCGGTGCCATGGTCGAAGACGTGGACCCTGGCTTCGACAACCCGGCCCCGACGTTCCGCGTATTGTGGGATGCGGGC
GTCGCGCGCTTTCTGCGCGACATCACGCCCGATCGCCTCGCGCTGATGGATCCGCTCCTGCACGAAGCCGCCGCACGGGG
CCGCAATGTGGACGCCCTGGCCTATCTCGACGCGACCGAGCGCCGGCGCGAACTGGGCGTGGCGATGCGGCGCTTCCATG
AGCGGTATGACCTGCTGGTGACGCCCACGCTCGCGTCGGCGCCACCGCGAGTGGGACAGCCCTGGTCCGCGCCGCATTGC
CTGCCGTTCAATCTGACGGGCCAGCCCGCCGCCAGCGTGCCATGTGGTGTCACACGCGCCGGGCTGCCGATTGGCCTTCA
AATCGTCGGCCCCAGCCACGCCGACGCCATGGTGTTGCGCGCTGCGCGCGCTTTCGAAACGACGTGCCGGTGGCCACTGT
GGGCGCCGCGCGCCTCATCCCCGACCCGACAAGGAGATCAAGCATGA

Upstream 100 bases:

>100_bases
CCCTGGCGGGACGCTTCCTCGCCCGCAAGATGCCGGCACGGGCCCTGCGCGGCAGTGCATCGCTTTGCCTGCTCGCCGTG
GCCGCGTGGTACGCCGTCCG

Downstream 100 bases:

>100_bases
CCGACATGGAAATCCGCGCCTTGATTGCCGCCTTCGCCAGTGCCTTTCGTGCCGGCGACGCCGATGGCGTAGCCGCCTGC
CTGGCAGACGACTTCACGTG

Product: putative amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MNDLIMSNPADLSATALLALYARRDLSPVETLDAILHRVAERDPACNAFRFIDADGAREQARASERRWRRGKPCGLLDGV
PVSFKDLLHVRGWPTRLGSLATTDTPQPDDCPAAARLREHGAVLLGKTNTSEFGTKGITESALAGITRNPWNTTHTPGGS
SGGAAAATALGLGPLHVATDGGGSIRAPSAACGVFGFKPGSGRVPCYPPAHSGTLFHVGPMARTVTDAALLLTAISGPDS
RDWHALPYEDRDWRTGLDDGIAGLRVAYSRTLGYLPVDPEVSALCDAAVRRLMALGAMVEDVDPGFDNPAPTFRVLWDAG
VARFLRDITPDRLALMDPLLHEAAARGRNVDALAYLDATERRRELGVAMRRFHERYDLLVTPTLASAPPRVGQPWSAPHC
LPFNLTGQPAASVPCGVTRAGLPIGLQIVGPSHADAMVLRAARAFETTCRWPLWAPRASSPTRQGDQA

Sequences:

>Translated_468_residues
MNDLIMSNPADLSATALLALYARRDLSPVETLDAILHRVAERDPACNAFRFIDADGAREQARASERRWRRGKPCGLLDGV
PVSFKDLLHVRGWPTRLGSLATTDTPQPDDCPAAARLREHGAVLLGKTNTSEFGTKGITESALAGITRNPWNTTHTPGGS
SGGAAAATALGLGPLHVATDGGGSIRAPSAACGVFGFKPGSGRVPCYPPAHSGTLFHVGPMARTVTDAALLLTAISGPDS
RDWHALPYEDRDWRTGLDDGIAGLRVAYSRTLGYLPVDPEVSALCDAAVRRLMALGAMVEDVDPGFDNPAPTFRVLWDAG
VARFLRDITPDRLALMDPLLHEAAARGRNVDALAYLDATERRRELGVAMRRFHERYDLLVTPTLASAPPRVGQPWSAPHC
LPFNLTGQPAASVPCGVTRAGLPIGLQIVGPSHADAMVLRAARAFETTCRWPLWAPRASSPTRQGDQA
>Mature_468_residues
MNDLIMSNPADLSATALLALYARRDLSPVETLDAILHRVAERDPACNAFRFIDADGAREQARASERRWRRGKPCGLLDGV
PVSFKDLLHVRGWPTRLGSLATTDTPQPDDCPAAARLREHGAVLLGKTNTSEFGTKGITESALAGITRNPWNTTHTPGGS
SGGAAAATALGLGPLHVATDGGGSIRAPSAACGVFGFKPGSGRVPCYPPAHSGTLFHVGPMARTVTDAALLLTAISGPDS
RDWHALPYEDRDWRTGLDDGIAGLRVAYSRTLGYLPVDPEVSALCDAAVRRLMALGAMVEDVDPGFDNPAPTFRVLWDAG
VARFLRDITPDRLALMDPLLHEAAARGRNVDALAYLDATERRRELGVAMRRFHERYDLLVTPTLASAPPRVGQPWSAPHC
LPFNLTGQPAASVPCGVTRAGLPIGLQIVGPSHADAMVLRAARAFETTCRWPLWAPRASSPTRQGDQA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=489, Percent_Identity=26.1758691206544, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI195972892, Length=486, Percent_Identity=24.6913580246914, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI166795287, Length=208, Percent_Identity=33.1730769230769, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17537465, Length=482, Percent_Identity=24.896265560166, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71990152, Length=501, Percent_Identity=26.3473053892216, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17556264, Length=322, Percent_Identity=26.0869565217391, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17543272, Length=446, Percent_Identity=24.6636771300448, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17538252, Length=511, Percent_Identity=24.26614481409, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17556278, Length=290, Percent_Identity=26.2068965517241, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17556276, Length=290, Percent_Identity=26.2068965517241, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320448, Length=520, Percent_Identity=25.5769230769231, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319685, Length=398, Percent_Identity=27.6381909547739, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323950, Length=417, Percent_Identity=25.1798561151079, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24644968, Length=496, Percent_Identity=24.1935483870968, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24652985, Length=486, Percent_Identity=26.3374485596708, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI19922090, Length=486, Percent_Identity=26.3374485596708, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24652981, Length=486, Percent_Identity=26.3374485596708, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24652983, Length=486, Percent_Identity=26.3374485596708, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI161078093, Length=493, Percent_Identity=26.7748478701826, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24648435, Length=247, Percent_Identity=29.9595141700405, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24648437, Length=247, Percent_Identity=29.9595141700405, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI45550774, Length=247, Percent_Identity=29.9595141700405, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24648113, Length=239, Percent_Identity=35.9832635983264, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24648441, Length=168, Percent_Identity=33.9285714285714, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24648439, Length=168, Percent_Identity=33.9285714285714, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21356731, Length=165, Percent_Identity=33.9393939393939, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 49934; Mature: 49934

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLIMSNPADLSATALLALYARRDLSPVETLDAILHRVAERDPACNAFRFIDADGAREQ
CCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHH
ARASERRWRRGKPCGLLDGVPVSFKDLLHVRGWPTRLGSLATTDTPQPDDCPAAARLREH
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCHHHHCCCCCCCCCCCCCCCHHHHHHHC
GAVLLGKTNTSEFGTKGITESALAGITRNPWNTTHTPGGSSGGAAAATALGLGPLHVATD
CCEEEECCCCHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEC
GGGSIRAPSAACGVFGFKPGSGRVPCYPPAHSGTLFHVGPMARTVTDAALLLTAISGPDS
CCCCCCCCCHHCCCEEECCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCC
RDWHALPYEDRDWRTGLDDGIAGLRVAYSRTLGYLPVDPEVSALCDAAVRRLMALGAMVE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DVDPGFDNPAPTFRVLWDAGVARFLRDITPDRLALMDPLLHEAAARGRNVDALAYLDATE
HCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCHHH
RRRELGVAMRRFHERYDLLVTPTLASAPPRVGQPWSAPHCLPFNLTGQPAASVPCGVTRA
HHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
GLPIGLQIVGPSHADAMVLRAARAFETTCRWPLWAPRASSPTRQGDQA
CCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNDLIMSNPADLSATALLALYARRDLSPVETLDAILHRVAERDPACNAFRFIDADGAREQ
CCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHH
ARASERRWRRGKPCGLLDGVPVSFKDLLHVRGWPTRLGSLATTDTPQPDDCPAAARLREH
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCHHHHCCCCCCCCCCCCCCCHHHHHHHC
GAVLLGKTNTSEFGTKGITESALAGITRNPWNTTHTPGGSSGGAAAATALGLGPLHVATD
CCEEEECCCCHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEC
GGGSIRAPSAACGVFGFKPGSGRVPCYPPAHSGTLFHVGPMARTVTDAALLLTAISGPDS
CCCCCCCCCHHCCCEEECCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCC
RDWHALPYEDRDWRTGLDDGIAGLRVAYSRTLGYLPVDPEVSALCDAAVRRLMALGAMVE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DVDPGFDNPAPTFRVLWDAGVARFLRDITPDRLALMDPLLHEAAARGRNVDALAYLDATE
HCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCHHH
RRRELGVAMRRFHERYDLLVTPTLASAPPRVGQPWSAPHCLPFNLTGQPAASVPCGVTRA
HHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
GLPIGLQIVGPSHADAMVLRAARAFETTCRWPLWAPRASSPTRQGDQA
CCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]