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The map label for this gene is tauD [H]

Identifier: 73538369

GI number: 73538369

Start: 1219206

End: 1220111

Strand: Direct

Name: tauD [H]

Synonym: Reut_B4542

Alternate gene names: 73538369

Gene position: 1219206-1220111 (Clockwise)

Preceding gene: 73538367

Following gene: 73538370

Centisome position: 44.72

GC content: 63.13

Gene sequence:

>906_bases
ATGAAAACGATTCACGCAGCAGACGGGACGATCACAGCCCCGGCCGTGGTGTCCCGCAGCGCCCTGCAGTCCGCCTTCAC
GCTGACGCGCATTTCACCGGCACTGGGTGCCGAAGTCGGCAATATCGACCTCAACGTACCGCTCGACGACGACACCATCG
CGGCCCTGCGGCGCGCACTGGTCGAGCATAAGGTCCTGGTGTTCCGCGATCAGGACATCACGCCGTCACAGCATGTGTCG
CTGGCGCGGCGCTTCGGCGAACTGGAAGTGCATCCCGCCTTTCCGCACCATGAGGAGTTCCCGGAACTGGTGCTGCTCGG
GGGCGACGACAAGAAGCCGGCGATGGAGAACGGCTATCACAGCGACGTGTCGTGGCGCGAGATCCCGTCGATGGCGTCGA
TGCTGCGTTGTGTGCAATGCCCGGAGATCGGCGGCGACACGGTCTGGGTCAACATGGCGCTTGCTTACGAGAAGTTGCCG
GAGCACCGCAAGCAGCAGATCGAGGGACTCTTCGCCGCGCACGACATCCTGCCCGCATTCGGCGACAAGATGACGCCGGA
ACAACGCAAACAGTTTCCGCCCGCGATCCATCCCGTCGTGCGCACGCATCCGGAAAGCGGCGAGAAGATCCTCTACGTGA
ACGGCGCCTTCGTCACGCACTTCTTGAACTTCCGTTCGCGCAACGCGGTGCGCGGGGCGTTCGAAGGCCAGTCCGAGAAG
CATGACCTGATGGAGTACCTGCTGCGTCAGCCTGCCATCCTCGAGTACCAGATGCGCCTGCGCTGGCGGCCCAACACCAT
CGCATTCTGGGACAACCGCTCGACCCAGCACTACGCTATCCAGGACTACTTTCCTGCCGTACGCCGAATGATGCGCGCCA
CGATCATCGGCGATCGTCCGTTCTGA

Upstream 100 bases:

>100_bases
AAGTTTCGACATGGTTTTCCCTAGCCACCCAACGCATTGGTTGCGCCTCGGTGCATCGTCAGCCAAAAATATACTCGCTA
ATATAAATTGGAGACAAGGC

Downstream 100 bases:

>100_bases
GCCAACGCATCAACCGGGAGACTCATATGAAATGGAAGCTGCTCGTTGGTATCGCCGCCATGGCATTGAGCCTGGTGGCC
AGGGCCGATACGTACCCCAG

Product: taurine dioxygenase

Products: NA

Alternate protein names: 2-aminoethanesulfonate dioxygenase; Sulfate starvation-induced protein 3; SSI3 [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MKTIHAADGTITAPAVVSRSALQSAFTLTRISPALGAEVGNIDLNVPLDDDTIAALRRALVEHKVLVFRDQDITPSQHVS
LARRFGELEVHPAFPHHEEFPELVLLGGDDKKPAMENGYHSDVSWREIPSMASMLRCVQCPEIGGDTVWVNMALAYEKLP
EHRKQQIEGLFAAHDILPAFGDKMTPEQRKQFPPAIHPVVRTHPESGEKILYVNGAFVTHFLNFRSRNAVRGAFEGQSEK
HDLMEYLLRQPAILEYQMRLRWRPNTIAFWDNRSTQHYAIQDYFPAVRRMMRATIIGDRPF

Sequences:

>Translated_301_residues
MKTIHAADGTITAPAVVSRSALQSAFTLTRISPALGAEVGNIDLNVPLDDDTIAALRRALVEHKVLVFRDQDITPSQHVS
LARRFGELEVHPAFPHHEEFPELVLLGGDDKKPAMENGYHSDVSWREIPSMASMLRCVQCPEIGGDTVWVNMALAYEKLP
EHRKQQIEGLFAAHDILPAFGDKMTPEQRKQFPPAIHPVVRTHPESGEKILYVNGAFVTHFLNFRSRNAVRGAFEGQSEK
HDLMEYLLRQPAILEYQMRLRWRPNTIAFWDNRSTQHYAIQDYFPAVRRMMRATIIGDRPF
>Mature_301_residues
MKTIHAADGTITAPAVVSRSALQSAFTLTRISPALGAEVGNIDLNVPLDDDTIAALRRALVEHKVLVFRDQDITPSQHVS
LARRFGELEVHPAFPHHEEFPELVLLGGDDKKPAMENGYHSDVSWREIPSMASMLRCVQCPEIGGDTVWVNMALAYEKLP
EHRKQQIEGLFAAHDILPAFGDKMTPEQRKQFPPAIHPVVRTHPESGEKILYVNGAFVTHFLNFRSRNAVRGAFEGQSEK
HDLMEYLLRQPAILEYQMRLRWRPNTIAFWDNRSTQHYAIQDYFPAVRRMMRATIIGDRPF

Specific function: Catalyzes the conversion of taurine and alpha ketoglutarate to sulfite, aminoacetaldehyde and succinate. Required for the utilization of taurine (2-aminoethanesulfonic acid) as an alternative sulfur source. Pentane-sulfonic acid, 3- (N-morpholino)propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=286, Percent_Identity=38.8111888111888, Blast_Score=217, Evalue=7e-58,
Organism=Saccharomyces cerevisiae, GI6322971, Length=292, Percent_Identity=27.7397260273973, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: =1.14.11.17 [H]

Molecular weight: Translated: 34197; Mature: 34197

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIHAADGTITAPAVVSRSALQSAFTLTRISPALGAEVGNIDLNVPLDDDTIAALRRAL
CCEEECCCCCEECHHHHHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCCCHHHHHHHHHH
VEHKVLVFRDQDITPSQHVSLARRFGELEVHPAFPHHEEFPELVLLGGDDKKPAMENGYH
HHCCEEEEECCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCC
SDVSWREIPSMASMLRCVQCPEIGGDTVWVNMALAYEKLPEHRKQQIEGLFAAHDILPAF
CCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDKMTPEQRKQFPPAIHPVVRTHPESGEKILYVNGAFVTHFLNFRSRNAVRGAFEGQSEK
CCCCCHHHHHCCCCCCCHHHHCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCHH
HDLMEYLLRQPAILEYQMRLRWRPNTIAFWDNRSTQHYAIQDYFPAVRRMMRATIIGDRP
HHHHHHHHHCCCCEEEEEEEEECCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHCCCCC
F
C
>Mature Secondary Structure
MKTIHAADGTITAPAVVSRSALQSAFTLTRISPALGAEVGNIDLNVPLDDDTIAALRRAL
CCEEECCCCCEECHHHHHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCCCHHHHHHHHHH
VEHKVLVFRDQDITPSQHVSLARRFGELEVHPAFPHHEEFPELVLLGGDDKKPAMENGYH
HHCCEEEEECCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCC
SDVSWREIPSMASMLRCVQCPEIGGDTVWVNMALAYEKLPEHRKQQIEGLFAAHDILPAF
CCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDKMTPEQRKQFPPAIHPVVRTHPESGEKILYVNGAFVTHFLNFRSRNAVRGAFEGQSEK
CCCCCHHHHHCCCCCCCHHHHCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCHH
HDLMEYLLRQPAILEYQMRLRWRPNTIAFWDNRSTQHYAIQDYFPAVRRMMRATIIGDRP
HHHHHHHHHCCCCEEEEEEEEECCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHCCCCC
F
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503; 2656410; 8774726; 7984428; 9287300; 11955067 [H]