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The map label for this gene is kdgR [H]

Identifier: 73538344

GI number: 73538344

Start: 1187810

End: 1188577

Strand: Reverse

Name: kdgR [H]

Synonym: Reut_B4517

Alternate gene names: 73538344

Gene position: 1188577-1187810 (Counterclockwise)

Preceding gene: 73538345

Following gene: 73538343

Centisome position: 43.6

GC content: 65.49

Gene sequence:

>768_bases
ATGGCGGAATCCGAGACGGGCGACAAGGCAGGGCAGGCCAGCGTGAAGACGGCGCTGCGCGTGATCGAGATCATGGAGAT
CTACGCACGCGAAGGGCGCTCGCTCACACTGACGGAACTCGCGAAGCTGCTCGGCGCGCCGATGTCGAGCTGCCTCGGCC
TGATCCGCACGCTCGCATCGCTCGGCTATCTCTACGAGACCGGACGGCGGCAGGGCTACTATCCGACCAGCCGGCTGCTC
AATATCGCCCAGCGCATCTCGCGCAACGACCCGCTGCTCGAACGCGTGCAGCCCGTGCTCGAAACCCTGCGCGACGCGAC
CGGAGAAACCGTGATCTTCGGCAAGCTGCAGGACGACGGGCGCGTGCTGTACCTGGAAGTGCGTGAATCACAGAACCCGG
TGCGCTATACCGCGACGCCGGGTGAATTGCGCGACGTGCATATCAATTCGATCGGCCGCGCAATCCTTGGTGCCATGACG
GACGCCGCGCGCGATGCCGCGTTGGCGAAGGTCTCGTTCCAACCCCGCACCGGGCGCACCGTGGCCTCACGCGAGGCGCT
GGAGCGCGAGATTGCAATGTGGCAGCAGCAGGGCTGGTATCCGAACTTCGGTGAATCATTCCCGGACCTGGGGGCGATTG
CTGTGCCTGTTGAAATCGGGGGCGCTGTGTACGGGATGTCGGTGGCCGGGCCGATTCACCGGGTGGAGTCCAGTGTGGAC
CCCATTGTCGCCGCCTTGCTGCGCGGGCAAGACGCCTTGCGGACATAG

Upstream 100 bases:

>100_bases
CGCCAGGCAATATCCGATCGTGGGCGCAAGGGCTGCCGTCGTCGGACGAGGCTTGAAGACGCGTACAATCCGCGCACGGC
AAGGCTGACAGGAACAGGAG

Downstream 100 bases:

>100_bases
CTCTCCGTATTCCTGAATATTCCAGTTGAGAGGCGGTCACCCGCCGCACTTGGTTTGCCGATAATTTCCCGTTGACACCG
GAGAATGATCGTTCTACCAT

Product: regulatory protein IclR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MAESETGDKAGQASVKTALRVIEIMEIYAREGRSLTLTELAKLLGAPMSSCLGLIRTLASLGYLYETGRRQGYYPTSRLL
NIAQRISRNDPLLERVQPVLETLRDATGETVIFGKLQDDGRVLYLEVRESQNPVRYTATPGELRDVHINSIGRAILGAMT
DAARDAALAKVSFQPRTGRTVASREALEREIAMWQQQGWYPNFGESFPDLGAIAVPVEIGGAVYGMSVAGPIHRVESSVD
PIVAALLRGQDALRT

Sequences:

>Translated_255_residues
MAESETGDKAGQASVKTALRVIEIMEIYAREGRSLTLTELAKLLGAPMSSCLGLIRTLASLGYLYETGRRQGYYPTSRLL
NIAQRISRNDPLLERVQPVLETLRDATGETVIFGKLQDDGRVLYLEVRESQNPVRYTATPGELRDVHINSIGRAILGAMT
DAARDAALAKVSFQPRTGRTVASREALEREIAMWQQQGWYPNFGESFPDLGAIAVPVEIGGAVYGMSVAGPIHRVESSVD
PIVAALLRGQDALRT
>Mature_254_residues
AESETGDKAGQASVKTALRVIEIMEIYAREGRSLTLTELAKLLGAPMSSCLGLIRTLASLGYLYETGRRQGYYPTSRLLN
IAQRISRNDPLLERVQPVLETLRDATGETVIFGKLQDDGRVLYLEVRESQNPVRYTATPGELRDVHINSIGRAILGAMTD
AARDAALAKVSFQPRTGRTVASREALEREIAMWQQQGWYPNFGESFPDLGAIAVPVEIGGAVYGMSVAGPIHRVESSVDP
IVAALLRGQDALRT

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=236, Percent_Identity=26.6949152542373, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1786468, Length=204, Percent_Identity=25.4901960784314, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082359, Length=224, Percent_Identity=23.6607142857143, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27830; Mature: 27699

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAESETGDKAGQASVKTALRVIEIMEIYAREGRSLTLTELAKLLGAPMSSCLGLIRTLAS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCHHHHHHHHHHHHH
LGYLYETGRRQGYYPTSRLLNIAQRISRNDPLLERVQPVLETLRDATGETVIFGKLQDDG
HHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
RVLYLEVRESQNPVRYTATPGELRDVHINSIGRAILGAMTDAARDAALAKVSFQPRTGRT
EEEEEEEECCCCCEEEECCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCH
VASREALEREIAMWQQQGWYPNFGESFPDLGAIAVPVEIGGAVYGMSVAGPIHRVESSVD
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCEEECCHHHHHHHHHHHHHH
PIVAALLRGQDALRT
HHHHHHHHCHHHHCC
>Mature Secondary Structure 
AESETGDKAGQASVKTALRVIEIMEIYAREGRSLTLTELAKLLGAPMSSCLGLIRTLAS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCHHHHHHHHHHHHH
LGYLYETGRRQGYYPTSRLLNIAQRISRNDPLLERVQPVLETLRDATGETVIFGKLQDDG
HHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
RVLYLEVRESQNPVRYTATPGELRDVHINSIGRAILGAMTDAARDAALAKVSFQPRTGRT
EEEEEEEECCCCCEEEECCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCH
VASREALEREIAMWQQQGWYPNFGESFPDLGAIAVPVEIGGAVYGMSVAGPIHRVESSVD
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCEEECCHHHHHHHHHHHHHH
PIVAALLRGQDALRT
HHHHHHHHCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]