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The map label for this gene is yagR [H]

Identifier: 73538334

GI number: 73538334

Start: 1179863

End: 1182076

Strand: Direct

Name: yagR [H]

Synonym: Reut_B4507

Alternate gene names: 73538334

Gene position: 1179863-1182076 (Clockwise)

Preceding gene: 73538333

Following gene: 73538335

Centisome position: 43.28

GC content: 67.52

Gene sequence:

>2214_bases
ATGAACGTGATCGGCGCCCCGCTAGACCGCACCGACGGTGCCCTCAAGGTCACCGGCCGCGCACGCTATGCCGCGGACAA
TCCGCTGCCCGGACTATTGCACGCGGTACTGGTGACCAGCACCGTTGCCAGCGGTGATATCGCGTCCATGGATACTGCCG
TAGCCGAGCGCATGCCCGGCGTACGCAAGGTGATGACGCCGTTCAACGCGCCGCGGCTGCCGCAGGCCGGCAAGGCCGCA
GCGGGAAAGCCACCGGCCGGGCGCGTACTGAACCTGCTGCAGGAGACGGAAGTCCACTACAACAACCAGCCGTTGGCCGT
GGTCGTTGCCGATACGCTGGAACAGGCGCGCGACGCCGCTGCGCATATCGTCATCCGCTACAGGACGAAGACGCCGGTGC
TCGACTTCGCCGCGGCCCGCGCGAGCGCGTACAAGCCCAAGGAAGCCAAGGATGAGCCGGCGGACAGCTCGCGCGGCGAC
ATGTCCGCCACCGACGGCGCGGCGGCGCGCCTCGACGCCACCTACTCCACGCCACTTGAAACCCACAACCCGATGGAGCC
GCACGCCACGGTTGCGGCCTGGCAAGGCGACATGCTCACGCTGTACGATGCCACGCAGTACGTGAGCGGCGTGCGCAAGA
CCGTCGCGCAAACCCTGGGCGTGCAGCCATCGAACGTGCGGGTGGTCTGCCCCTTCGTTGGCGGTGGCTTTGGCTGCAAG
GGCTCGACGTGGTCGCACGTGGTGCTCGCCGCCATGGCCGCGCGCGAAGCCGGGCATCCGGTCAAGCTGGTGCTGGACCG
CCCGCAGATGTTCGGCCCCGTGGGCGGACGGCCACGCACCGAGCAACATGTCGTACTGGCCGCGCGCGCCGACGGCACGC
TTACCAGCATGCGCCACGAGGTGACGGCCTGCACCTCGTTCATGGAAGACTGGCTGGAACCGTGTGCGCTACTCACGCGC
ATGCTGTATGCCGTACCGAACCAGCAGACCAGCCACCGCCTGCTCAAGCTGAACATCGGTACGCCGACCTTCATGCGCGC
GCCTGGCGAGGCGTCGGGCAGCTTTGCGCTCGAATGCGCGATGGATGAGCTGGCGTACAAGCTTGGCATGGACCCGGTTG
CGCTGCGGTTGTGCAACTACGCCGACGCGGATCCCGGCAAGGAACTGCCATTCTCGAGCAAGTCGCTGCGGGAGTGCTAC
CGCGACGCTGCCGCGCGCTTTGGCTGGGCGCAGCGCAATCCGGCACCGCGTTCCATGCGAACTGAAGATGGCCGGCTCGT
CGGCATGGGCATGGCCACGACGACCTATCCTGCCAACCGCTCGGCCGCCAGCGCACTGGCGCGCATCCTGCCTGACGGCA
CGGCGCTGGTGCAGTCGGGCTCGCAAGATCTGGGAACAGGCACCTTCACCGTGATGACGCAGGTTGCTGCCGACGCCCTG
GGCCTGCCACCGGACAAGGTCCGCTTCGAGCTCGGCGACACCAATTTCCCCGAAGCCCCGGTATCGGGTGGATCGCAATC
GGTCGCCAGCGTCGCCCCTGCGGTGCAGGCGGCATGCATGGCGGCGCGGCTGGCGCTGGTGAAGCTAGCCGTTGCGGACG
CGGCCTCGCCGCTATCCGGCGCGCCGCCCGAGGATGTCGATGTCGTCGACGGCTGGCTGCAGCGGCGGTCCGAGCCATCG
CGCCGCGAACCCGTGGCGGCGCCCATTGCGCGGCGCGGCGGCCAGCCTGTCGAAGCGCGCATGAGTGCGCGGCCTGGCGA
CGAGCGCAAAAAATTCTCGATGCACAGCTTTGGCGCGGTGTTCGCGGAAGTCCACGTCGACCCGGACCTGGGCGAGATCC
GCATGCAGCGCATCGTGGCCAGCTATGGCGTGGGGCGGCTGCTGAACCGCAAGACGGCCCACAGCCAGCTCATGGGAGGT
ATCGTATGGGGCCTGAGCATGGCGCTGCACGAGCAGTCCGAACTGGATCTGGTTAGCGGCCGTATCGCCAATGGCAACCT
GGCCGAATATCATGTGCCGGTCAACGCTGATGTCGGCGCTATCGACATTGCGGTGCTGGACGAGGATGATCCGCATATCA
ACGCGCTTGGCACCAAGGGCATCGGCGAGATCGGCATTGTCGGCGTGGCCGCGGCGCTGGCCAACGCGGTGTATCACGCA
ACGGGAAAACGCATCCGCGATTTGCCGCTGACGGTCGACAAGCTGGTCGCCTGA

Upstream 100 bases:

>100_bases
TGCTGGACGGCGCGCGGCCGCTTCCCAATAACGCCTACAAGCTCACCCTGGCGCAGCATGCCGTGGTGCGCGCGCTGGGC
ATCGCAGCCGGAGGCCTGGC

Downstream 100 bases:

>100_bases
AGCGCAATAGCCAGCAGTAGCCCGCAGTAGCCAAAATGAACAACGAAGAAACGGGAGAACCCATTGTCAGAGCCGGAAAC
CTTCAGTCCTACGGGCCGCT

Product: xanthine dehydrogenase, molybdenum binding subunit apoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 737; Mature: 737

Protein sequence:

>737_residues
MNVIGAPLDRTDGALKVTGRARYAADNPLPGLLHAVLVTSTVASGDIASMDTAVAERMPGVRKVMTPFNAPRLPQAGKAA
AGKPPAGRVLNLLQETEVHYNNQPLAVVVADTLEQARDAAAHIVIRYRTKTPVLDFAAARASAYKPKEAKDEPADSSRGD
MSATDGAAARLDATYSTPLETHNPMEPHATVAAWQGDMLTLYDATQYVSGVRKTVAQTLGVQPSNVRVVCPFVGGGFGCK
GSTWSHVVLAAMAAREAGHPVKLVLDRPQMFGPVGGRPRTEQHVVLAARADGTLTSMRHEVTACTSFMEDWLEPCALLTR
MLYAVPNQQTSHRLLKLNIGTPTFMRAPGEASGSFALECAMDELAYKLGMDPVALRLCNYADADPGKELPFSSKSLRECY
RDAAARFGWAQRNPAPRSMRTEDGRLVGMGMATTTYPANRSAASALARILPDGTALVQSGSQDLGTGTFTVMTQVAADAL
GLPPDKVRFELGDTNFPEAPVSGGSQSVASVAPAVQAACMAARLALVKLAVADAASPLSGAPPEDVDVVDGWLQRRSEPS
RREPVAAPIARRGGQPVEARMSARPGDERKKFSMHSFGAVFAEVHVDPDLGEIRMQRIVASYGVGRLLNRKTAHSQLMGG
IVWGLSMALHEQSELDLVSGRIANGNLAEYHVPVNADVGAIDIAVLDEDDPHINALGTKGIGEIGIVGVAAALANAVYHA
TGKRIRDLPLTVDKLVA

Sequences:

>Translated_737_residues
MNVIGAPLDRTDGALKVTGRARYAADNPLPGLLHAVLVTSTVASGDIASMDTAVAERMPGVRKVMTPFNAPRLPQAGKAA
AGKPPAGRVLNLLQETEVHYNNQPLAVVVADTLEQARDAAAHIVIRYRTKTPVLDFAAARASAYKPKEAKDEPADSSRGD
MSATDGAAARLDATYSTPLETHNPMEPHATVAAWQGDMLTLYDATQYVSGVRKTVAQTLGVQPSNVRVVCPFVGGGFGCK
GSTWSHVVLAAMAAREAGHPVKLVLDRPQMFGPVGGRPRTEQHVVLAARADGTLTSMRHEVTACTSFMEDWLEPCALLTR
MLYAVPNQQTSHRLLKLNIGTPTFMRAPGEASGSFALECAMDELAYKLGMDPVALRLCNYADADPGKELPFSSKSLRECY
RDAAARFGWAQRNPAPRSMRTEDGRLVGMGMATTTYPANRSAASALARILPDGTALVQSGSQDLGTGTFTVMTQVAADAL
GLPPDKVRFELGDTNFPEAPVSGGSQSVASVAPAVQAACMAARLALVKLAVADAASPLSGAPPEDVDVVDGWLQRRSEPS
RREPVAAPIARRGGQPVEARMSARPGDERKKFSMHSFGAVFAEVHVDPDLGEIRMQRIVASYGVGRLLNRKTAHSQLMGG
IVWGLSMALHEQSELDLVSGRIANGNLAEYHVPVNADVGAIDIAVLDEDDPHINALGTKGIGEIGIVGVAAALANAVYHA
TGKRIRDLPLTVDKLVA
>Mature_737_residues
MNVIGAPLDRTDGALKVTGRARYAADNPLPGLLHAVLVTSTVASGDIASMDTAVAERMPGVRKVMTPFNAPRLPQAGKAA
AGKPPAGRVLNLLQETEVHYNNQPLAVVVADTLEQARDAAAHIVIRYRTKTPVLDFAAARASAYKPKEAKDEPADSSRGD
MSATDGAAARLDATYSTPLETHNPMEPHATVAAWQGDMLTLYDATQYVSGVRKTVAQTLGVQPSNVRVVCPFVGGGFGCK
GSTWSHVVLAAMAAREAGHPVKLVLDRPQMFGPVGGRPRTEQHVVLAARADGTLTSMRHEVTACTSFMEDWLEPCALLTR
MLYAVPNQQTSHRLLKLNIGTPTFMRAPGEASGSFALECAMDELAYKLGMDPVALRLCNYADADPGKELPFSSKSLRECY
RDAAARFGWAQRNPAPRSMRTEDGRLVGMGMATTTYPANRSAASALARILPDGTALVQSGSQDLGTGTFTVMTQVAADAL
GLPPDKVRFELGDTNFPEAPVSGGSQSVASVAPAVQAACMAARLALVKLAVADAASPLSGAPPEDVDVVDGWLQRRSEPS
RREPVAAPIARRGGQPVEARMSARPGDERKKFSMHSFGAVFAEVHVDPDLGEIRMQRIVASYGVGRLLNRKTAHSQLMGG
IVWGLSMALHEQSELDLVSGRIANGNLAEYHVPVNADVGAIDIAVLDEDDPHINALGTKGIGEIGIVGVAAALANAVYHA
TGKRIRDLPLTVDKLVA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=762, Percent_Identity=26.509186351706, Blast_Score=146, Evalue=7e-35,
Organism=Homo sapiens, GI91823271, Length=758, Percent_Identity=25.5936675461741, Blast_Score=135, Evalue=1e-31,
Organism=Escherichia coli, GI1786478, Length=741, Percent_Identity=37.6518218623482, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI1789230, Length=762, Percent_Identity=29.6587926509186, Blast_Score=230, Evalue=3e-61,
Organism=Escherichia coli, GI1789246, Length=799, Percent_Identity=25.9073842302879, Blast_Score=168, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI17540638, Length=735, Percent_Identity=22.4489795918367, Blast_Score=122, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI32566215, Length=552, Percent_Identity=21.5579710144928, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24647199, Length=705, Percent_Identity=23.9716312056738, Blast_Score=138, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24647195, Length=743, Percent_Identity=23.956931359354, Blast_Score=135, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24647197, Length=734, Percent_Identity=24.1144414168937, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24647193, Length=741, Percent_Identity=23.0769230769231, Blast_Score=116, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24647201, Length=729, Percent_Identity=22.0850480109739, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17737937, Length=562, Percent_Identity=27.2241992882562, Blast_Score=109, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 78063; Mature: 78063

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVIGAPLDRTDGALKVTGRARYAADNPLPGLLHAVLVTSTVASGDIASMDTAVAERMPG
CCCCCCCCCCCCCCEEEECCEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
VRKVMTPFNAPRLPQAGKAAAGKPPAGRVLNLLQETEVHYNNQPLAVVVADTLEQARDAA
HHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHH
AHIVIRYRTKTPVLDFAAARASAYKPKEAKDEPADSSRGDMSATDGAAARLDATYSTPLE
EEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHEECCCCCCCCC
THNPMEPHATVAAWQGDMLTLYDATQYVSGVRKTVAQTLGVQPSNVRVVCPFVGGGFGCK
CCCCCCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCC
GSTWSHVVLAAMAAREAGHPVKLVLDRPQMFGPVGGRPRTEQHVVLAARADGTLTSMRHE
CCCHHHHHHHHHHHHHCCCCEEEEECCCHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHH
VTACTSFMEDWLEPCALLTRMLYAVPNQQTSHRLLKLNIGTPTFMRAPGEASGSFALECA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEECCCCCCCCEEEEHH
MDELAYKLGMDPVALRLCNYADADPGKELPFSSKSLRECYRDAAARFGWAQRNPAPRSMR
HHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
TEDGRLVGMGMATTTYPANRSAASALARILPDGTALVQSGSQDLGTGTFTVMTQVAADAL
CCCCEEEEECCEEECCCCCHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHC
GLPPDKVRFELGDTNFPEAPVSGGSQSVASVAPAVQAACMAARLALVKLAVADAASPLSG
CCCCHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
APPEDVDVVDGWLQRRSEPSRREPVAAPIARRGGQPVEARMSARPGDERKKFSMHSFGAV
CCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHEE
FAEVHVDPDLGEIRMQRIVASYGVGRLLNRKTAHSQLMGGIVWGLSMALHEQSELDLVSG
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCC
RIANGNLAEYHVPVNADVGAIDIAVLDEDDPHINALGTKGIGEIGIVGVAAALANAVYHA
EECCCCCEEEEECCCCCCCEEEEEEECCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHH
TGKRIRDLPLTVDKLVA
CCCHHHCCCCCHHHHCC
>Mature Secondary Structure
MNVIGAPLDRTDGALKVTGRARYAADNPLPGLLHAVLVTSTVASGDIASMDTAVAERMPG
CCCCCCCCCCCCCCEEEECCEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
VRKVMTPFNAPRLPQAGKAAAGKPPAGRVLNLLQETEVHYNNQPLAVVVADTLEQARDAA
HHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHH
AHIVIRYRTKTPVLDFAAARASAYKPKEAKDEPADSSRGDMSATDGAAARLDATYSTPLE
EEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHEECCCCCCCCC
THNPMEPHATVAAWQGDMLTLYDATQYVSGVRKTVAQTLGVQPSNVRVVCPFVGGGFGCK
CCCCCCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCC
GSTWSHVVLAAMAAREAGHPVKLVLDRPQMFGPVGGRPRTEQHVVLAARADGTLTSMRHE
CCCHHHHHHHHHHHHHCCCCEEEEECCCHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHH
VTACTSFMEDWLEPCALLTRMLYAVPNQQTSHRLLKLNIGTPTFMRAPGEASGSFALECA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEECCCCCCCCEEEEHH
MDELAYKLGMDPVALRLCNYADADPGKELPFSSKSLRECYRDAAARFGWAQRNPAPRSMR
HHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
TEDGRLVGMGMATTTYPANRSAASALARILPDGTALVQSGSQDLGTGTFTVMTQVAADAL
CCCCEEEEECCEEECCCCCHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHC
GLPPDKVRFELGDTNFPEAPVSGGSQSVASVAPAVQAACMAARLALVKLAVADAASPLSG
CCCCHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
APPEDVDVVDGWLQRRSEPSRREPVAAPIARRGGQPVEARMSARPGDERKKFSMHSFGAV
CCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHEE
FAEVHVDPDLGEIRMQRIVASYGVGRLLNRKTAHSQLMGGIVWGLSMALHEQSELDLVSG
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCC
RIANGNLAEYHVPVNADVGAIDIAVLDEDDPHINALGTKGIGEIGIVGVAAALANAVYHA
EECCCCCEEEEECCCCCCCEEEEEEECCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHH
TGKRIRDLPLTVDKLVA
CCCHHHCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]