| Definition | Ralstonia eutropha JMP134 chromosome chromosome 2, complete sequence. |
|---|---|
| Accession | NC_007348 |
| Length | 2,726,152 |
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The map label for this gene is yvaG [H]
Identifier: 73538331
GI number: 73538331
Start: 1177227
End: 1178021
Strand: Direct
Name: yvaG [H]
Synonym: Reut_B4504
Alternate gene names: 73538331
Gene position: 1177227-1178021 (Clockwise)
Preceding gene: 73538330
Following gene: 73538332
Centisome position: 43.18
GC content: 65.03
Gene sequence:
>795_bases ATGAACATTGATCTGTCGGGCAAGACCGCCCTGGTTTCGGGCTCCACTGCAGGTATCGGCTTCGCCACCGCGCGCGGCCT CGCACAAGCCGGCGCGCGCGTCGTCCTCAACGGCCGCAAGGCGGATGCACTGGCGAAGGCGGCGGACACGCTGCGCGCAG AGGCGCTGGACGCGGACCTAATTCCCTTCGCGGGCGATCTGGCCACGCAGCAAGGCGTGGATGCGCTGCTCGCGCAGGTA CCGGCGGTCGATATTCTGGTCAACAACCTCGGCATCTTCAATCCGCAGGACTTCTTCGAAACGCCCGACAGCGAATGGAC GCGGTTCTTCGAGACCAATGTGATGTCAGGGGTGCGCCTGTCTCGCGCCTATGCGCCGGGCATGGTGCAGCGCAAGTGGG GCCGCATCGTGTTCATCTCCTCCGAATCGGGGCTCAACATTCCGGTCGAGATGATCCACTACGGTTTCTCCAAGACCGCG CAACTCGCGGTGTCGCGCGGGCTGGCTAAACGGCTGGCTGGCACCGGCGTGACAGTGAACGCCGTACTGCCCGGGCCGAC GCTGTCCGAAGGCGTCGAGGAAATGCTTGCTGACGAAGTCAGGCGCACCGGCAAGCCCGTGGAGGAAGTGGCCGCCGATT TCGTCAGGACCCATCGCAGCACATCCATCATCCAGCGTGCGGCGACCGTCGACGAGGTGGCCAATATGGTCGTCTATGTG TGCTCGAAGCAGGCATCCGCGACCACGGGCGCCGCGCTGCGCGTCGATGGCGGCGTGGTCGACACCATCGCGTAA
Upstream 100 bases:
>100_bases AAACGCAGGGTCGGCGGGCAGTGGCACGTCGCGTGCCGGCTACGCCATTCCGTGAAGTGCCTGCCCCTGATGCAGGCAAA CCATCCTGAAGGGTATCGCC
Downstream 100 bases:
>100_bases TCGCATGAACGAAGCTGTCGTAATTTCTACATGTGTGCTGAAAATTTGAGGCACGCAACGTAGCATGTGCGTGGCGCGGG TGCTCCCGCGCCATCGGCAC
Product: Short-chain dehydrogenase/reductase SDR
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 264; Mature: 264
Protein sequence:
>264_residues MNIDLSGKTALVSGSTAGIGFATARGLAQAGARVVLNGRKADALAKAADTLRAEALDADLIPFAGDLATQQGVDALLAQV PAVDILVNNLGIFNPQDFFETPDSEWTRFFETNVMSGVRLSRAYAPGMVQRKWGRIVFISSESGLNIPVEMIHYGFSKTA QLAVSRGLAKRLAGTGVTVNAVLPGPTLSEGVEEMLADEVRRTGKPVEEVAADFVRTHRSTSIIQRAATVDEVANMVVYV CSKQASATTGAALRVDGGVVDTIA
Sequences:
>Translated_264_residues MNIDLSGKTALVSGSTAGIGFATARGLAQAGARVVLNGRKADALAKAADTLRAEALDADLIPFAGDLATQQGVDALLAQV PAVDILVNNLGIFNPQDFFETPDSEWTRFFETNVMSGVRLSRAYAPGMVQRKWGRIVFISSESGLNIPVEMIHYGFSKTA QLAVSRGLAKRLAGTGVTVNAVLPGPTLSEGVEEMLADEVRRTGKPVEEVAADFVRTHRSTSIIQRAATVDEVANMVVYV CSKQASATTGAALRVDGGVVDTIA >Mature_264_residues MNIDLSGKTALVSGSTAGIGFATARGLAQAGARVVLNGRKADALAKAADTLRAEALDADLIPFAGDLATQQGVDALLAQV PAVDILVNNLGIFNPQDFFETPDSEWTRFFETNVMSGVRLSRAYAPGMVQRKWGRIVFISSESGLNIPVEMIHYGFSKTA QLAVSRGLAKRLAGTGVTVNAVLPGPTLSEGVEEMLADEVRRTGKPVEEVAADFVRTHRSTSIIQRAATVDEVANMVVYV CSKQASATTGAALRVDGGVVDTIA
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=31.5175097276265, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI32483357, Length=260, Percent_Identity=31.5384615384615, Blast_Score=99, Evalue=5e-21, Organism=Homo sapiens, GI33667109, Length=185, Percent_Identity=36.2162162162162, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI109715829, Length=253, Percent_Identity=28.8537549407115, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI126723750, Length=262, Percent_Identity=29.3893129770992, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI7705855, Length=185, Percent_Identity=32.972972972973, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI7705925, Length=264, Percent_Identity=27.6515151515151, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI7706318, Length=208, Percent_Identity=29.8076923076923, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI19923817, Length=263, Percent_Identity=26.2357414448669, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI126723191, Length=184, Percent_Identity=33.1521739130435, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI66933014, Length=194, Percent_Identity=25.7731958762887, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI10190746, Length=212, Percent_Identity=32.0754716981132, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI142976729, Length=190, Percent_Identity=28.4210526315789, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI210032110, Length=189, Percent_Identity=29.1005291005291, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI209862901, Length=215, Percent_Identity=30.6976744186047, Blast_Score=72, Evalue=8e-13, Organism=Homo sapiens, GI19923983, Length=215, Percent_Identity=30.6976744186047, Blast_Score=72, Evalue=8e-13, Organism=Homo sapiens, GI186928839, Length=216, Percent_Identity=30.5555555555556, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI226371731, Length=191, Percent_Identity=31.9371727748691, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI146231950, Length=209, Percent_Identity=33.4928229665072, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI7657478, Length=200, Percent_Identity=32.5, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI20149619, Length=192, Percent_Identity=31.25, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI10190704, Length=262, Percent_Identity=28.2442748091603, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI40254992, Length=257, Percent_Identity=28.0155642023346, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=258, Percent_Identity=31.7829457364341, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1790717, Length=260, Percent_Identity=28.4615384615385, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI1787905, Length=266, Percent_Identity=30.4511278195489, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=30.1526717557252, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1789208, Length=265, Percent_Identity=27.9245283018868, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI2367365, Length=254, Percent_Identity=29.5275590551181, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1788459, Length=262, Percent_Identity=28.2442748091603, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=32.2222222222222, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1786812, Length=269, Percent_Identity=29.7397769516729, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI2367175, Length=260, Percent_Identity=31.1538461538462, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1789057, Length=265, Percent_Identity=27.1698113207547, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI87082160, Length=183, Percent_Identity=26.775956284153, Blast_Score=65, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17560676, Length=259, Percent_Identity=30.5019305019305, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=30.1960784313725, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17561402, Length=264, Percent_Identity=29.5454545454545, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=31.1023622047244, Blast_Score=103, Evalue=9e-23, Organism=Caenorhabditis elegans, GI115534694, Length=261, Percent_Identity=31.8007662835249, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=31.0861423220974, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=30.188679245283, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=31.6981132075472, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=28.3582089552239, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=28.8389513108614, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=26.3157894736842, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17568967, Length=269, Percent_Identity=24.5353159851301, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=29.4339622641509, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI25147288, Length=266, Percent_Identity=28.1954887218045, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=28.3018867924528, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17538480, Length=191, Percent_Identity=30.8900523560209, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=27.9245283018868, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17560150, Length=267, Percent_Identity=26.2172284644195, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17562990, Length=267, Percent_Identity=26.9662921348315, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI193203115, Length=174, Percent_Identity=28.735632183908, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17560220, Length=269, Percent_Identity=27.1375464684015, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=27.6515151515151, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI32565532, Length=216, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI193203117, Length=175, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=232, Percent_Identity=25.8620689655172, Blast_Score=72, Evalue=1e-13, Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=34.6303501945525, Blast_Score=111, Evalue=6e-25, Organism=Drosophila melanogaster, GI24644339, Length=261, Percent_Identity=32.183908045977, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=32.9411764705882, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=31.2741312741313, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=29.3436293436293, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI24639444, Length=266, Percent_Identity=27.8195488721804, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI24644337, Length=261, Percent_Identity=30.6513409961686, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI21358495, Length=188, Percent_Identity=32.9787234042553, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24643142, Length=260, Percent_Identity=27.3076923076923, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI45553409, Length=279, Percent_Identity=27.2401433691756, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI24647948, Length=279, Percent_Identity=27.2401433691756, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI24647946, Length=279, Percent_Identity=27.2401433691756, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI18859837, Length=206, Percent_Identity=27.1844660194175, Blast_Score=66, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 27763; Mature: 27763
Theoretical pI: Translated: 5.38; Mature: 5.38
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNIDLSGKTALVSGSTAGIGFATARGLAQAGARVVLNGRKADALAKAADTLRAEALDADL CCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCC IPFAGDLATQQGVDALLAQVPAVDILVNNLGIFNPQDFFETPDSEWTRFFETNVMSGVRL CCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHCHHH SRAYAPGMVQRKWGRIVFISSESGLNIPVEMIHYGFSKTAQLAVSRGLAKRLAGTGVTVN HHHHCCCHHHHCCCCEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEE AVLPGPTLSEGVEEMLADEVRRTGKPVEEVAADFVRTHRSTSIIQRAATVDEVANMVVYV EEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CSKQASATTGAALRVDGGVVDTIA HCCCCCCCCCCEEEECCCEECCCC >Mature Secondary Structure MNIDLSGKTALVSGSTAGIGFATARGLAQAGARVVLNGRKADALAKAADTLRAEALDADL CCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCC IPFAGDLATQQGVDALLAQVPAVDILVNNLGIFNPQDFFETPDSEWTRFFETNVMSGVRL CCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHCHHH SRAYAPGMVQRKWGRIVFISSESGLNIPVEMIHYGFSKTAQLAVSRGLAKRLAGTGVTVN HHHHCCCHHHHCCCCEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEE AVLPGPTLSEGVEEMLADEVRRTGKPVEEVAADFVRTHRSTSIIQRAATVDEVANMVVYV EEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CSKQASATTGAALRVDGGVVDTIA HCCCCCCCCCCEEEECCCEECCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]