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The map label for this gene is azlB [H]

Identifier: 73538327

GI number: 73538327

Start: 1172185

End: 1172658

Strand: Reverse

Name: azlB [H]

Synonym: Reut_B4500

Alternate gene names: 73538327

Gene position: 1172658-1172185 (Counterclockwise)

Preceding gene: 73538336

Following gene: 73538326

Centisome position: 43.02

GC content: 63.08

Gene sequence:

>474_bases
GTGCAAGCCATTGAGCTGGACCGTACGGATCGGCGCCTGCTGGGCGTTTTGCAGCAGCAAGGCAGGGCTTCCAACCTGGA
ACTGGCCGAAGCGATTGCGCTGTCGCCGGCACAGACTTTGCGACGCCACCGCCGCCTGGAGGAGAGCGGCATCATCAAGC
GCTACGAGGCGCGGCTCGATGCCGCGGCGCTCGGCCTTGGCGTGGTGGCCTTTATCCACGTGACCATGGAACGCGGCCAT
ATCCGCGACCTGTCGAACTTCAAGAGCCTGGTGGCGGAACTCGCGCAGATCCAGGAGTGCTTCTCTGTGACGGGCGATAT
CGACTACGTGCTGAAGGTCGTCGCCAAGGACCTGAAGTCGCTGTCGGACTTCCTGCTCGACACGCTGATGCGCATTCCGG
GCGTGAGCGGCGTGAAGTCAAGCGTGTGCCTGGACGAGATCAAGTGCACCAGCGCCGTGCCGCTCGATATGTAA

Upstream 100 bases:

>100_bases
GTGTATATTCTGGCCGACAAAATTGGATTTCATTAATGACGCAGGGAAACCCTGAATTACGAAATCGGATTGTGCAAAAA
CTTGCTTAGGGGAAACAAAA

Downstream 100 bases:

>100_bases
GGCGGGGCTATTGCCGGTACTGGAATACACTCGGAAGCAATGCCCCTACGTGGCCCCCGGCCGCCGCCCAAGATGTCAAA
GCCCCACATCCTGACCTACA

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MQAIELDRTDRRLLGVLQQQGRASNLELAEAIALSPAQTLRRHRRLEESGIIKRYEARLDAAALGLGVVAFIHVTMERGH
IRDLSNFKSLVAELAQIQECFSVTGDIDYVLKVVAKDLKSLSDFLLDTLMRIPGVSGVKSSVCLDEIKCTSAVPLDM

Sequences:

>Translated_157_residues
MQAIELDRTDRRLLGVLQQQGRASNLELAEAIALSPAQTLRRHRRLEESGIIKRYEARLDAAALGLGVVAFIHVTMERGH
IRDLSNFKSLVAELAQIQECFSVTGDIDYVLKVVAKDLKSLSDFLLDTLMRIPGVSGVKSSVCLDEIKCTSAVPLDM
>Mature_157_residues
MQAIELDRTDRRLLGVLQQQGRASNLELAEAIALSPAQTLRRHRRLEESGIIKRYEARLDAAALGLGVVAFIHVTMERGH
IRDLSNFKSLVAELAQIQECFSVTGDIDYVLKVVAKDLKSLSDFLLDTLMRIPGVSGVKSSVCLDEIKCTSAVPLDM

Specific function: Transcriptional repressor of the azlBCD operon involved in branched-chain amino acid transport [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=147, Percent_Identity=39.4557823129252, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI87081742, Length=151, Percent_Identity=32.4503311258278, Blast_Score=95, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17334; Mature: 17334

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAIELDRTDRRLLGVLQQQGRASNLELAEAIALSPAQTLRRHRRLEESGIIKRYEARLD
CCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
AAALGLGVVAFIHVTMERGHIRDLSNFKSLVAELAQIQECFSVTGDIDYVLKVVAKDLKS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LSDFLLDTLMRIPGVSGVKSSVCLDEIKCTSAVPLDM
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQAIELDRTDRRLLGVLQQQGRASNLELAEAIALSPAQTLRRHRRLEESGIIKRYEARLD
CCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
AAALGLGVVAFIHVTMERGHIRDLSNFKSLVAELAQIQECFSVTGDIDYVLKVVAKDLKS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LSDFLLDTLMRIPGVSGVKSSVCLDEIKCTSAVPLDM
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9287000; 9308178; 9384377 [H]