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The map label for this gene is yhcS [C]

Identifier: 73538321

GI number: 73538321

Start: 1166394

End: 1167344

Strand: Direct

Name: yhcS [C]

Synonym: Reut_B4494

Alternate gene names: 73538321

Gene position: 1166394-1167344 (Clockwise)

Preceding gene: 73538317

Following gene: 73538322

Centisome position: 42.79

GC content: 60.04

Gene sequence:

>951_bases
GTGTCGGAGTTAGAGCGGCCCTCTGTGCCGCACGGGGCCATGCTGCACAAGAAACCTGATGAGATCGTGGACTGGGGCGA
CTGGGACAATTTCTGCCGGGTCGTCGAGGCCGGGGGCTTTACTGCCGCGAGTGACCGTAGCGGCGTTCCGAAGTCGTCGA
TCAGCCTGTCGCTGGCCCGCCTGGAAGCCCGGCTGGGCAATCGGCTGCTTGACCGGACCACGCGCAAGATTCGCGTAACG
GATCTGGGTCAGACGCTATATGACCGGATCACGCCTTTGCTGAATGAACTTCGGGAAGCGGATAACGATGCGCGGTCAAC
ACGGCAGCAGGTATCAGGCACGCTACGACTGGCAGCGCCGTATGAAACAGGCAGGATTCATCTGGCGCCGGCACTGGTGA
AGCTGCTCAGGGCGCATCCGGATTTGAAGGTCGAGATTGACGATACGCGGAGGATTCCCGACCTGCTGGAGCACCGATAC
GACATTGCGTTCGTCAAGACCGATGCAAGACTGCCCGACAGTTCGCTGGTCAGCAAACACGTTGTGGCAATGGAACGCGC
TTTCTACGCAGCGCCGGAGATGATTGCCAGGCGCGGGCTCCCGCGGCAACTCCCCGATATCGGGTCGTGGCCCATGATCG
TGGACGGTGACGATACTTATTGGGATCTGTTTGAAAACGGGCGGGAAGTCGGGCGGGTAGCCGTATGCCCGGCCATCCGG
ACGCCGAATGTTGAGATTCGCGTGCGCACCGCCATCGAAGGTCTTGGCGTCGTACGGCTGATGCCGGCATACATCGAAGA
TCAGGTCAAGCGAGGAGAACTGGTGCGGTTGTTCCCTGCATTTCTTTCGTCTCCGCTCAGGGTATATGCGCTGACTCCGG
CCCGAAGGCTTGTACCACCCAAGGTAAGAGCATTGCTGAATGCATTCGAAATCCGGGAGACTGACGCGTGA

Upstream 100 bases:

>100_bases
TCACGAATAAAATGGCCCAATCCATGCACTGGTTCCCCTTCAGAAAAGGCGCGACGCTTCATAGGATTCATGGAATACCG
GAGGGTGATGCCTCCGGGAT

Downstream 100 bases:

>100_bases
CCGCTCCGCTAGCCGGTCCCGGCGTCCTTGATAACTGTCCACTCGAGTACCAGTGATCGCCAGCCTGCGCAAGTGCGAAC
CACAGCCCCGTCCCGCTGCC

Product: regulatory protein LysR

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSELERPSVPHGAMLHKKPDEIVDWGDWDNFCRVVEAGGFTAASDRSGVPKSSISLSLARLEARLGNRLLDRTTRKIRVT
DLGQTLYDRITPLLNELREADNDARSTRQQVSGTLRLAAPYETGRIHLAPALVKLLRAHPDLKVEIDDTRRIPDLLEHRY
DIAFVKTDARLPDSSLVSKHVVAMERAFYAAPEMIARRGLPRQLPDIGSWPMIVDGDDTYWDLFENGREVGRVAVCPAIR
TPNVEIRVRTAIEGLGVVRLMPAYIEDQVKRGELVRLFPAFLSSPLRVYALTPARRLVPPKVRALLNAFEIRETDA

Sequences:

>Translated_316_residues
MSELERPSVPHGAMLHKKPDEIVDWGDWDNFCRVVEAGGFTAASDRSGVPKSSISLSLARLEARLGNRLLDRTTRKIRVT
DLGQTLYDRITPLLNELREADNDARSTRQQVSGTLRLAAPYETGRIHLAPALVKLLRAHPDLKVEIDDTRRIPDLLEHRY
DIAFVKTDARLPDSSLVSKHVVAMERAFYAAPEMIARRGLPRQLPDIGSWPMIVDGDDTYWDLFENGREVGRVAVCPAIR
TPNVEIRVRTAIEGLGVVRLMPAYIEDQVKRGELVRLFPAFLSSPLRVYALTPARRLVPPKVRALLNAFEIRETDA
>Mature_315_residues
SELERPSVPHGAMLHKKPDEIVDWGDWDNFCRVVEAGGFTAASDRSGVPKSSISLSLARLEARLGNRLLDRTTRKIRVTD
LGQTLYDRITPLLNELREADNDARSTRQQVSGTLRLAAPYETGRIHLAPALVKLLRAHPDLKVEIDDTRRIPDLLEHRYD
IAFVKTDARLPDSSLVSKHVVAMERAFYAAPEMIARRGLPRQLPDIGSWPMIVDGDDTYWDLFENGREVGRVAVCPAIRT
PNVEIRVRTAIEGLGVVRLMPAYIEDQVKRGELVRLFPAFLSSPLRVYALTPARRLVPPKVRALLNAFEIRETDA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=287, Percent_Identity=29.9651567944251, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI145693193, Length=292, Percent_Identity=26.027397260274, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787128, Length=295, Percent_Identity=27.1186440677966, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789440, Length=255, Percent_Identity=25.4901960784314, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786401, Length=279, Percent_Identity=26.1648745519713, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI87081978, Length=280, Percent_Identity=27.8571428571429, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787589, Length=263, Percent_Identity=25.8555133079848, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788481, Length=260, Percent_Identity=26.1538461538462, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788748, Length=119, Percent_Identity=38.655462184874, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35568; Mature: 35437

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELERPSVPHGAMLHKKPDEIVDWGDWDNFCRVVEAGGFTAASDRSGVPKSSISLSLAR
CCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHH
LEARLGNRLLDRTTRKIRVTDLGQTLYDRITPLLNELREADNDARSTRQQVSGTLRLAAP
HHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEECC
YETGRIHLAPALVKLLRAHPDLKVEIDDTRRIPDLLEHRYDIAFVKTDARLPDSSLVSKH
CCCCEEEHHHHHHHHHHCCCCCEEEECCCCCCHHHHHCCCCEEEEEECCCCCCHHHHHHH
VVAMERAFYAAPEMIARRGLPRQLPDIGSWPMIVDGDDTYWDLFENGREVGRVAVCPAIR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHHHHHCCHHHCEEEEECCCC
TPNVEIRVRTAIEGLGVVRLMPAYIEDQVKRGELVRLFPAFLSSPLRVYALTPARRLVPP
CCCEEEEEEEHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCHHHCCCH
KVRALLNAFEIRETDA
HHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SELERPSVPHGAMLHKKPDEIVDWGDWDNFCRVVEAGGFTAASDRSGVPKSSISLSLAR
CCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHH
LEARLGNRLLDRTTRKIRVTDLGQTLYDRITPLLNELREADNDARSTRQQVSGTLRLAAP
HHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEECC
YETGRIHLAPALVKLLRAHPDLKVEIDDTRRIPDLLEHRYDIAFVKTDARLPDSSLVSKH
CCCCEEEHHHHHHHHHHCCCCCEEEECCCCCCHHHHHCCCCEEEEEECCCCCCHHHHHHH
VVAMERAFYAAPEMIARRGLPRQLPDIGSWPMIVDGDDTYWDLFENGREVGRVAVCPAIR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHHHHHCCHHHCEEEEECCCC
TPNVEIRVRTAIEGLGVVRLMPAYIEDQVKRGELVRLFPAFLSSPLRVYALTPARRLVPP
CCCEEEEEEEHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCHHHCCCH
KVRALLNAFEIRETDA
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]