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The map label for this gene is tehA [H]

Identifier: 73538312

GI number: 73538312

Start: 1154344

End: 1155339

Strand: Reverse

Name: tehA [H]

Synonym: Reut_B4485

Alternate gene names: 73538312

Gene position: 1155339-1154344 (Counterclockwise)

Preceding gene: 73538313

Following gene: 73538308

Centisome position: 42.38

GC content: 54.92

Gene sequence:

>996_bases
ATGCATACCTTCCCATCACCCTCTGAACAGACGATTGAGAAAAACGAAATATCGGTGAAGAACCTTCCTGTGAACCTGTT
TGCTTCGGTCATGGGAATTTCCGGGCTTGCCCTTGCATGGAGACAGACGGCAAGCCAGTTTGGCGTGAGTCCGATCATTT
CCGATGTGATCAGCGTGGTGGCGGTGATCGCATTCCTGGTATTGACAGTCTCGTACGCTGCAAAGATCGCAAAACATCCC
GATGCGGTAGTGAAGGAATTTTGCCACCCGATCGCTGGCAATTTCTTCGGGACGGTGCCGATCGCAATCCTTCTGATTTC
TTCTCTTATCGGTCCATCGAATGAAGCCATCGCGGAAGTCGTCTGGACGGTGGGAGCGGTTGCGACGATTGCCCTCGCTT
TCACAATCTTCAGTCGGCTTGTTCGTGGAAAGATCGATTCGGGACACGCCTTGCCTGCGTGGTTGATTCCGGGGGTGGCG
ACACTTGACATCGCCGTGGCGGGTGGAAGCATGCGCATGCCGTGGGCCCGGGAACTGAACATCGTTTCCCTTGGCATCGG
AACCGTTCTTGCGCTGGTGCTGTTCACCATGATCATCTCGCGGCTGATTCATCATGAAAAGCTCGCGAGTCACATGATTC
CGTCGCTGATGATTCTCATCGCGCCGTTCGAAGTGGGGTTCCTGGCCTATACGAACTTCACGCAAAGCATCGATGTGTTT
GCGGCGATCCTGTTCTATTTCGGGCTGTTTCTGTTCTTTACCCTGTTTCTCAAGGTATTCCGTCGGAGCATTCCGTTTTC
CGCTGGCTGGTGGGGGGTGAGTTTTCCGATCGCCGCACTGACCAATGCGACGTTGAGGTATGCGGATACGGTGCGCCTGT
GGCCGATTACGGTGTTGTCCGTCGTTCTGCTTGCCTTTGTGTCCGGGGTGATCGTGATGCTTTCTGTCCGGACGTTGCGT
GTCGTCTTCAACGGCGAGCTGCTGTCCGGGCGGTGA

Upstream 100 bases:

>100_bases
TGATCAAGTCGTTGGATCGGCACGCGATGTCCAAACCTATACTTGCCCGGGCAGTGCATGGCAACAGGTCCATGGCATGG
ACATTCGCTGAGGAAAATCG

Downstream 100 bases:

>100_bases
CTGGCATCCGTGGCGTTATTGGTGCGAGCTGGTCTGACGCATCCCGTCAGCACCAGCCCGCGCCGGTCGACGCAGGCTCA
ATGTGCCGCAGCGGCAAGCG

Product: C4-dicarboxylate transporter/malic acid transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MHTFPSPSEQTIEKNEISVKNLPVNLFASVMGISGLALAWRQTASQFGVSPIISDVISVVAVIAFLVLTVSYAAKIAKHP
DAVVKEFCHPIAGNFFGTVPIAILLISSLIGPSNEAIAEVVWTVGAVATIALAFTIFSRLVRGKIDSGHALPAWLIPGVA
TLDIAVAGGSMRMPWARELNIVSLGIGTVLALVLFTMIISRLIHHEKLASHMIPSLMILIAPFEVGFLAYTNFTQSIDVF
AAILFYFGLFLFFTLFLKVFRRSIPFSAGWWGVSFPIAALTNATLRYADTVRLWPITVLSVVLLAFVSGVIVMLSVRTLR
VVFNGELLSGR

Sequences:

>Translated_331_residues
MHTFPSPSEQTIEKNEISVKNLPVNLFASVMGISGLALAWRQTASQFGVSPIISDVISVVAVIAFLVLTVSYAAKIAKHP
DAVVKEFCHPIAGNFFGTVPIAILLISSLIGPSNEAIAEVVWTVGAVATIALAFTIFSRLVRGKIDSGHALPAWLIPGVA
TLDIAVAGGSMRMPWARELNIVSLGIGTVLALVLFTMIISRLIHHEKLASHMIPSLMILIAPFEVGFLAYTNFTQSIDVF
AAILFYFGLFLFFTLFLKVFRRSIPFSAGWWGVSFPIAALTNATLRYADTVRLWPITVLSVVLLAFVSGVIVMLSVRTLR
VVFNGELLSGR
>Mature_331_residues
MHTFPSPSEQTIEKNEISVKNLPVNLFASVMGISGLALAWRQTASQFGVSPIISDVISVVAVIAFLVLTVSYAAKIAKHP
DAVVKEFCHPIAGNFFGTVPIAILLISSLIGPSNEAIAEVVWTVGAVATIALAFTIFSRLVRGKIDSGHALPAWLIPGVA
TLDIAVAGGSMRMPWARELNIVSLGIGTVLALVLFTMIISRLIHHEKLASHMIPSLMILIAPFEVGFLAYTNFTQSIDVF
AAILFYFGLFLFFTLFLKVFRRSIPFSAGWWGVSFPIAALTNATLRYADTVRLWPITVLSVVLLAFVSGVIVMLSVRTLR
VVFNGELLSGR

Specific function: Responsible for potassium tellurite resistance when present in high copy number, probably by increasing the reduction rate of tellurite to metallic tellurium within the bacterium. Otherwise, phenotypically silent [H]

COG id: COG1275

COG function: function code P; Tellurite resistance protein and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family [H]

Homologues:

Organism=Escherichia coli, GI1787699, Length=314, Percent_Identity=28.0254777070064, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004695
- InterPro:   IPR011552 [H]

Pfam domain/function: PF03595 C4dic_mal_tran [H]

EC number: NA

Molecular weight: Translated: 35829; Mature: 35829

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTFPSPSEQTIEKNEISVKNLPVNLFASVMGISGLALAWRQTASQFGVSPIISDVISVV
CCCCCCCCHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AVIAFLVLTVSYAAKIAKHPDAVVKEFCHPIAGNFFGTVPIAILLISSLIGPSNEAIAEV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHH
VWTVGAVATIALAFTIFSRLVRGKIDSGHALPAWLIPGVATLDIAVAGGSMRMPWARELN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHEEEEEECCCCCCCHHHCCC
IVSLGIGTVLALVLFTMIISRLIHHEKLASHMIPSLMILIAPFEVGFLAYTNFTQSIDVF
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAILFYFGLFLFFTLFLKVFRRSIPFSAGWWGVSFPIAALTNATLRYADTVRLWPITVLS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VVLLAFVSGVIVMLSVRTLRVVFNGELLSGR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MHTFPSPSEQTIEKNEISVKNLPVNLFASVMGISGLALAWRQTASQFGVSPIISDVISVV
CCCCCCCCHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AVIAFLVLTVSYAAKIAKHPDAVVKEFCHPIAGNFFGTVPIAILLISSLIGPSNEAIAEV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHH
VWTVGAVATIALAFTIFSRLVRGKIDSGHALPAWLIPGVATLDIAVAGGSMRMPWARELN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHEEEEEECCCCCCCHHHCCC
IVSLGIGTVLALVLFTMIISRLIHHEKLASHMIPSLMILIAPFEVGFLAYTNFTQSIDVF
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAILFYFGLFLFFTLFLKVFRRSIPFSAGWWGVSFPIAALTNATLRYADTVRLWPITVLS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VVLLAFVSGVIVMLSVRTLRVVFNGELLSGR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2060788; 9097039; 9278503; 8169225 [H]