Click here to switch to the map view.

The map label for this gene is bvgS [H]

Identifier: 73538299

GI number: 73538299

Start: 1138786

End: 1140825

Strand: Direct

Name: bvgS [H]

Synonym: Reut_B4472

Alternate gene names: 73538299

Gene position: 1138786-1140825 (Clockwise)

Preceding gene: 73538293

Following gene: 73538301

Centisome position: 41.77

GC content: 68.33

Gene sequence:

>2040_bases
GTGGCTTGCCAGCCGCTCGGCCCGGTGGCCGCGACGACATTCGGCCAGCGTGGCTGCCGACTGAATAGGAAATTTCTCCA
GCCAGACTCCGACGCGTCTGAAACTACGGCGATACGCGCATCCATAGAGTCATGGATCGCGCCCCGCAATCGCAATGCCG
TGCAGGGCTGTCCTCCATGCCCGTCGCCTGCATTGAATTTGTCCGCCCTGCCCCCGCCAATCGTCTGGCTGGCTTTGAGC
CTGACGCTGCTGCTCGCTTCTGCGCTATTCGCAGCGCGCGTACGCGTGTTGCGGCGCCAGCTCGCCCGCAGCCAGGCCTG
CACGGCACGGCTGCGCCAGCGCCTGACGTTGCACACGGCGGTGCTGGACAGCATTCCCCTGCCCGTCTATGTGCGCGACG
CCCAGCAGCGGCTCATCACCTGCAACCGGCGTTATGAGGAACTGGTCGGCGCGTCACGCGCATCGTTGCGAGGCCTGCCG
CCGGACATGCCGGAACAGCTCGCCGGCGTGATCACAGACGCCGCTGAACTCTCCGAGGACTACCGCGACGTCATTGCCTC
CGGCCGCGCGCTCAGCAAGGACCGCTGCCTGCACATCCAGGGCGAAAAGCGGCATGTGCTGAACTGGGTTGCACCGTTGC
AAGGCCCCGGCAAGACCGTGACGGCACTGGCCGGCGGCTGGGTGGACCTGACCGAGCGCCACGACATGCTCGCCCAGCTG
GCCGAAGCCAAGGCGCGTGCCGAGGCGGCAAATCGGGCCAAGTCCACCTTCCTCGCCTCGGTCAGCCATGAGATCCGGAC
ACCGATGAACGCTGTGGCCGGCATGATCGAGCTCGCCCTGAAACGGCCCGAGATGCCGTCCGACGAGCGCCGCATGCTGT
CCACCGCGCACGATTCCGCGCTGGCACTGCTCGCATTGATCGATGACATTCTCGACTTGTCGAAGATGGAAGCGGGCAAG
CTGCGCGTCCATCCCGTTCCCGCCAGCTTGCCGGCGCTGGTGGAGGAAGTCCTGCAGATGCTCGGCCCAGTAGCCGCGCA
GAAGCCATTGCCGCTGGTGCCGGTCGTCGACCCGGGCATCGCGGCGGCGCATATGGTCGATCCGCTGCGTGTGAAGCAGG
TACTTGGCAATCTGGTCTCCAACGCCATCCGCTTCACCGACAAGGGCGAGGTACGCGTGCATCTGCACGGCGGCCCAGTG
CATGCGGGAAAGCAGGAGATCGTGTTGACGGTCGCCGATACCGGCATTGGCATCGCGCACGCCGACCAGGCGCGCCTGTT
CCAGCCGTTCGAGCAGGCCCACGACCGATCGCGGCCACAATCCGGCGGCACCGGGCTGGGCCTGGCCATCTGCCGCCGGC
TGGTCGCGGCCATGGGCGGCCAGATCCGTCTCGAAAGCCGCGCGGGGGCTGGCACAAGTGTGCGGGTTACCCTGCGGCTG
CGCACAGCCTGCTTGCCGGTCATGCCCGAGCCGGCGGCCCTTTCCGCATGTGCCGCTGCCACTGATTCGCTGCACGTGCT
GGTCGTGGACGACCATGCGCCGAACCGCCTGCTACTGAAGTGGCAGCTCGAACATCTGGGCCATCGCGTGGACACGGCCG
CGGATGGCAGCGAGGCGCTGGAGCGGCTGGCCGAGTCTCCGACGGCCTCCCAGGGGCCATTCGACCTCGTGATCTGCGAC
TGTGCGATGCCAGTCATGGATGGCCAGACCTTTGCCCGCGCACTGCGCGCGCGCCGCGACGCGCCCGCCCGAATTCCGGT
GATCGGCTGCACGGCCAGCGCGGTGCCCGAGGACCACCAGGCCGCGCTGGCGGCTGGCATGGATGGCGTGCTGGTCAAGC
CGGTCGGCCTGGCGGCACTCGGCGAAGCCGTGCGCGCGTATGCCTGTGCGGGTCGCAGGCTGCCGGCGACGGCACAGATG
CCGTTGCCATGGCCCACGGCCGGCGCAGAGCCGGTGCGCGCGTCGCATGCGCCGGATCGATGGTGCGAGGTCTGTCGTGC
CATGAATGTCCAATGCGAGCGGGCCGGGGACGGCCCCTGA

Upstream 100 bases:

>100_bases
GCCAGCAGGCCAGTGATCGGGGTTGGCGCGGTCAGCATCGGAAAACTCCATCGCGGACAGGTAACAGACGAGCAGGGCAA
GACAATGATAGCGTTGCCCG

Downstream 100 bases:

>100_bases
TACTGGCCTGAATTGCGGCCAAGACATTGGCGGAACTGGCATTCGCCACCTACACAAACTCGCCTGCGGGGTGCAGCGAG
ACAAGCCTTGATTGATGACT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 679; Mature: 678

Protein sequence:

>679_residues
MACQPLGPVAATTFGQRGCRLNRKFLQPDSDASETTAIRASIESWIAPRNRNAVQGCPPCPSPALNLSALPPPIVWLALS
LTLLLASALFAARVRVLRRQLARSQACTARLRQRLTLHTAVLDSIPLPVYVRDAQQRLITCNRRYEELVGASRASLRGLP
PDMPEQLAGVITDAAELSEDYRDVIASGRALSKDRCLHIQGEKRHVLNWVAPLQGPGKTVTALAGGWVDLTERHDMLAQL
AEAKARAEAANRAKSTFLASVSHEIRTPMNAVAGMIELALKRPEMPSDERRMLSTAHDSALALLALIDDILDLSKMEAGK
LRVHPVPASLPALVEEVLQMLGPVAAQKPLPLVPVVDPGIAAAHMVDPLRVKQVLGNLVSNAIRFTDKGEVRVHLHGGPV
HAGKQEIVLTVADTGIGIAHADQARLFQPFEQAHDRSRPQSGGTGLGLAICRRLVAAMGGQIRLESRAGAGTSVRVTLRL
RTACLPVMPEPAALSACAAATDSLHVLVVDDHAPNRLLLKWQLEHLGHRVDTAADGSEALERLAESPTASQGPFDLVICD
CAMPVMDGQTFARALRARRDAPARIPVIGCTASAVPEDHQAALAAGMDGVLVKPVGLAALGEAVRAYACAGRRLPATAQM
PLPWPTAGAEPVRASHAPDRWCEVCRAMNVQCERAGDGP

Sequences:

>Translated_679_residues
MACQPLGPVAATTFGQRGCRLNRKFLQPDSDASETTAIRASIESWIAPRNRNAVQGCPPCPSPALNLSALPPPIVWLALS
LTLLLASALFAARVRVLRRQLARSQACTARLRQRLTLHTAVLDSIPLPVYVRDAQQRLITCNRRYEELVGASRASLRGLP
PDMPEQLAGVITDAAELSEDYRDVIASGRALSKDRCLHIQGEKRHVLNWVAPLQGPGKTVTALAGGWVDLTERHDMLAQL
AEAKARAEAANRAKSTFLASVSHEIRTPMNAVAGMIELALKRPEMPSDERRMLSTAHDSALALLALIDDILDLSKMEAGK
LRVHPVPASLPALVEEVLQMLGPVAAQKPLPLVPVVDPGIAAAHMVDPLRVKQVLGNLVSNAIRFTDKGEVRVHLHGGPV
HAGKQEIVLTVADTGIGIAHADQARLFQPFEQAHDRSRPQSGGTGLGLAICRRLVAAMGGQIRLESRAGAGTSVRVTLRL
RTACLPVMPEPAALSACAAATDSLHVLVVDDHAPNRLLLKWQLEHLGHRVDTAADGSEALERLAESPTASQGPFDLVICD
CAMPVMDGQTFARALRARRDAPARIPVIGCTASAVPEDHQAALAAGMDGVLVKPVGLAALGEAVRAYACAGRRLPATAQM
PLPWPTAGAEPVRASHAPDRWCEVCRAMNVQCERAGDGP
>Mature_678_residues
ACQPLGPVAATTFGQRGCRLNRKFLQPDSDASETTAIRASIESWIAPRNRNAVQGCPPCPSPALNLSALPPPIVWLALSL
TLLLASALFAARVRVLRRQLARSQACTARLRQRLTLHTAVLDSIPLPVYVRDAQQRLITCNRRYEELVGASRASLRGLPP
DMPEQLAGVITDAAELSEDYRDVIASGRALSKDRCLHIQGEKRHVLNWVAPLQGPGKTVTALAGGWVDLTERHDMLAQLA
EAKARAEAANRAKSTFLASVSHEIRTPMNAVAGMIELALKRPEMPSDERRMLSTAHDSALALLALIDDILDLSKMEAGKL
RVHPVPASLPALVEEVLQMLGPVAAQKPLPLVPVVDPGIAAAHMVDPLRVKQVLGNLVSNAIRFTDKGEVRVHLHGGPVH
AGKQEIVLTVADTGIGIAHADQARLFQPFEQAHDRSRPQSGGTGLGLAICRRLVAAMGGQIRLESRAGAGTSVRVTLRLR
TACLPVMPEPAALSACAAATDSLHVLVVDDHAPNRLLLKWQLEHLGHRVDTAADGSEALERLAESPTASQGPFDLVICDC
AMPVMDGQTFARALRARRDAPARIPVIGCTASAVPEDHQAALAAGMDGVLVKPVGLAALGEAVRAYACAGRRLPATAQMP
LPWPTAGAEPVRASHAPDRWCEVCRAMNVQCERAGDGP

Specific function: Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=569, Percent_Identity=30.7557117750439, Blast_Score=248, Evalue=7e-67,
Organism=Escherichia coli, GI48994928, Length=550, Percent_Identity=30.7272727272727, Blast_Score=208, Evalue=1e-54,
Organism=Escherichia coli, GI1789149, Length=243, Percent_Identity=41.1522633744856, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI87081816, Length=398, Percent_Identity=33.4170854271357, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI145693157, Length=259, Percent_Identity=37.4517374517375, Blast_Score=172, Evalue=9e-44,
Organism=Escherichia coli, GI1786600, Length=240, Percent_Identity=28.3333333333333, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1788549, Length=398, Percent_Identity=24.8743718592965, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=29.4820717131474, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1788393, Length=280, Percent_Identity=27.8571428571429, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87082128, Length=231, Percent_Identity=29.004329004329, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786783, Length=241, Percent_Identity=29.045643153527, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=28.2608695652174, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787894, Length=226, Percent_Identity=29.2035398230088, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=27.3542600896861, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1789808, Length=229, Percent_Identity=30.1310043668122, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72500; Mature: 72369

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACQPLGPVAATTFGQRGCRLNRKFLQPDSDASETTAIRASIESWIAPRNRNAVQGCPPC
CCCCCCCCHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
PSPALNLSALPPPIVWLALSLTLLLASALFAARVRVLRRQLARSQACTARLRQRLTLHTA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLDSIPLPVYVRDAQQRLITCNRRYEELVGASRASLRGLPPDMPEQLAGVITDAAELSED
HHHCCCCCEEEECHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHH
YRDVIASGRALSKDRCLHIQGEKRHVLNWVAPLQGPGKTVTALAGGWVDLTERHDMLAQL
HHHHHHCCCCCCCCCEEEECCCCHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHH
AEAKARAEAANRAKSTFLASVSHEIRTPMNAVAGMIELALKRPEMPSDERRMLSTAHDSA
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LALLALIDDILDLSKMEAGKLRVHPVPASLPALVEEVLQMLGPVAAQKPLPLVPVVDPGI
HHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCHHHCCCCCEECCCCCCC
AAAHMVDPLRVKQVLGNLVSNAIRFTDKGEVRVHLHGGPVHAGKQEIVLTVADTGIGIAH
HHHHHCCHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCCCEEEEEEECCCCCEEC
ADQARLFQPFEQAHDRSRPQSGGTGLGLAICRRLVAAMGGQIRLESRAGAGTSVRVTLRL
CCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEE
RTACLPVMPEPAALSACAAATDSLHVLVVDDHAPNRLLLKWQLEHLGHRVDTAADGSEAL
EEHHCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCEEEEEEEHHHCCCHHCCCCCHHHHH
ERLAESPTASQGPFDLVICDCAMPVMDGQTFARALRARRDAPARIPVIGCTASAVPEDHQ
HHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHH
AALAAGMDGVLVKPVGLAALGEAVRAYACAGRRLPATAQMPLPWPTAGAEPVRASHAPDR
HHHHHCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
WCEVCRAMNVQCERAGDGP
HHHHHHHCCCEECCCCCCC
>Mature Secondary Structure 
ACQPLGPVAATTFGQRGCRLNRKFLQPDSDASETTAIRASIESWIAPRNRNAVQGCPPC
CCCCCCCHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
PSPALNLSALPPPIVWLALSLTLLLASALFAARVRVLRRQLARSQACTARLRQRLTLHTA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLDSIPLPVYVRDAQQRLITCNRRYEELVGASRASLRGLPPDMPEQLAGVITDAAELSED
HHHCCCCCEEEECHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHH
YRDVIASGRALSKDRCLHIQGEKRHVLNWVAPLQGPGKTVTALAGGWVDLTERHDMLAQL
HHHHHHCCCCCCCCCEEEECCCCHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHH
AEAKARAEAANRAKSTFLASVSHEIRTPMNAVAGMIELALKRPEMPSDERRMLSTAHDSA
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LALLALIDDILDLSKMEAGKLRVHPVPASLPALVEEVLQMLGPVAAQKPLPLVPVVDPGI
HHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCHHHCCCCCEECCCCCCC
AAAHMVDPLRVKQVLGNLVSNAIRFTDKGEVRVHLHGGPVHAGKQEIVLTVADTGIGIAH
HHHHHCCHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCCCEEEEEEECCCCCEEC
ADQARLFQPFEQAHDRSRPQSGGTGLGLAICRRLVAAMGGQIRLESRAGAGTSVRVTLRL
CCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEE
RTACLPVMPEPAALSACAAATDSLHVLVVDDHAPNRLLLKWQLEHLGHRVDTAADGSEAL
EEHHCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCEEEEEEEHHHCCCHHCCCCCHHHHH
ERLAESPTASQGPFDLVICDCAMPVMDGQTFARALRARRDAPARIPVIGCTASAVPEDHQ
HHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHH
AALAAGMDGVLVKPVGLAALGEAVRAYACAGRRLPATAQMPLPWPTAGAEPVRASHAPDR
HHHHHCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
WCEVCRAMNVQCERAGDGP
HHHHHHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]