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The map label for this gene is yxnA [H]

Identifier: 73538267

GI number: 73538267

Start: 1098436

End: 1099446

Strand: Reverse

Name: yxnA [H]

Synonym: Reut_B4439

Alternate gene names: 73538267

Gene position: 1099446-1098436 (Counterclockwise)

Preceding gene: 73538271

Following gene: 161611271

Centisome position: 40.33

GC content: 68.35

Gene sequence:

>1011_bases
ATGGCTGATGCTAAGCCCGTTCAAAGCGCCCGTTGCGTGGTCATCACCGGTGCCTCGGCCGGCATCGGGCGCGCCACGGC
ACGCGCGTTCGGCCGCATGGCATGGCGCGTGGGTCTGCTGGCGCGCGGTCAGGACGGGCTGCGCGCAGCGGCATCGGAAG
TCGAGCGGAGCGGTGGGGTCGCCCTGCCGATCGTCGTGGACGTCGCGGACCATGACGCCGTGGAACGGGCCGCGGCGCGG
GTGGAGGCCGAACTGGGGCCGATCGACGTATGGATCAACTGCGCGATGGCGACGATCTTCTGCCGCGCCGACCAGATAGC
ACCGGCGGACTTCGTCCGCGCGACGCACGTCACCTACCTGGGCGCCGTGTGGGGCACGCTGGCGGCGCTGGGCCGCATGA
AGACGCGCAACCGGGGCGTGATCGTGCAGGTTGGCTCGGCGCTCGCGTATCGCTCGATTCCGCTGCAGGCGCCGTACTGT
GGCGCGAAAAGCGCGTTGCGCGGCTTTACCGATTCGCTGCGTTCGGAGCTGATTCACGACGGCAGCCGCATCCACCTGAC
CATGGTGCACCTGTCGGCGTTCAATACGCCCCAATTCGACTGGGGCCGCACGTGCATGCACCGGCAGCCGCAGCCCGTGC
CGCCGATCTTCCAGCCGGAGGTCGCCGCCGACGCCATTGTATGGGCGGCGCTGCATCATCGCCGCGAGTCATGGGTGGGC
TGGCCGGCGGTGCAGGCCATCATCGGTACGCGGCTGATTCCTGGTGTGCTTGACCGCTTCCTGGCGCGGCACGGATTCGA
TTCGCAGCATACCGATCAGCCCTTGCCGCGTGACCGGCCTGACAACCTGTACCACCCCGTCAAAGGGGACCATGGCGCGC
ACGGCAGGTTTTCCGACCGTGCCGCGCGCAGCAGCATCCAGTGGTGGCTCAATACGCATCGCTGGGTGATGGCTGCAGTC
GTGATGATCGTGATGGCGCTGGTCGCGGGGTGGCTTTGGCGAAGCCGCTGA

Upstream 100 bases:

>100_bases
GGCCATGTGCGAAATGCGAAGCGCAACGCATGCCGGGCGACACATCACACTGGGATGCATCTTGCATGGGTTACCGAAGT
TGTCCGTTGGAAAACGCAGC

Downstream 100 bases:

>100_bases
CAGGCCGGCGCCATTTGGGCAGGGAATCAATCAAGGAGAACGAACATGCTCAGCGATACCGAATTCCGACAACGCCTCAG
GCAAGCCCTGGCGCAGGTTC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MADAKPVQSARCVVITGASAGIGRATARAFGRMAWRVGLLARGQDGLRAAASEVERSGGVALPIVVDVADHDAVERAAAR
VEAELGPIDVWINCAMATIFCRADQIAPADFVRATHVTYLGAVWGTLAALGRMKTRNRGVIVQVGSALAYRSIPLQAPYC
GAKSALRGFTDSLRSELIHDGSRIHLTMVHLSAFNTPQFDWGRTCMHRQPQPVPPIFQPEVAADAIVWAALHHRRESWVG
WPAVQAIIGTRLIPGVLDRFLARHGFDSQHTDQPLPRDRPDNLYHPVKGDHGAHGRFSDRAARSSIQWWLNTHRWVMAAV
VMIVMALVAGWLWRSR

Sequences:

>Translated_336_residues
MADAKPVQSARCVVITGASAGIGRATARAFGRMAWRVGLLARGQDGLRAAASEVERSGGVALPIVVDVADHDAVERAAAR
VEAELGPIDVWINCAMATIFCRADQIAPADFVRATHVTYLGAVWGTLAALGRMKTRNRGVIVQVGSALAYRSIPLQAPYC
GAKSALRGFTDSLRSELIHDGSRIHLTMVHLSAFNTPQFDWGRTCMHRQPQPVPPIFQPEVAADAIVWAALHHRRESWVG
WPAVQAIIGTRLIPGVLDRFLARHGFDSQHTDQPLPRDRPDNLYHPVKGDHGAHGRFSDRAARSSIQWWLNTHRWVMAAV
VMIVMALVAGWLWRSR
>Mature_335_residues
ADAKPVQSARCVVITGASAGIGRATARAFGRMAWRVGLLARGQDGLRAAASEVERSGGVALPIVVDVADHDAVERAAARV
EAELGPIDVWINCAMATIFCRADQIAPADFVRATHVTYLGAVWGTLAALGRMKTRNRGVIVQVGSALAYRSIPLQAPYCG
AKSALRGFTDSLRSELIHDGSRIHLTMVHLSAFNTPQFDWGRTCMHRQPQPVPPIFQPEVAADAIVWAALHHRRESWVGW
PAVQAIIGTRLIPGVLDRFLARHGFDSQHTDQPLPRDRPDNLYHPVKGDHGAHGRFSDRAARSSIQWWLNTHRWVMAAVV
MIVMALVAGWLWRSR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4503817, Length=236, Percent_Identity=29.6610169491525, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI142976729, Length=259, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI210032110, Length=167, Percent_Identity=34.7305389221557, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI7706318, Length=167, Percent_Identity=31.7365269461078, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI40254992, Length=175, Percent_Identity=30.2857142857143, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI31543615, Length=248, Percent_Identity=27.0161290322581, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI20149619, Length=187, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=265, Percent_Identity=27.9245283018868, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193203115, Length=263, Percent_Identity=27.7566539923954, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17567345, Length=173, Percent_Identity=28.3236994219653, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=239, Percent_Identity=29.7071129707113, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21356301, Length=262, Percent_Identity=28.6259541984733, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24581726, Length=221, Percent_Identity=27.6018099547511, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21358495, Length=207, Percent_Identity=30.4347826086957, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36837; Mature: 36706

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADAKPVQSARCVVITGASAGIGRATARAFGRMAWRVGLLARGQDGLRAAASEVERSGGV
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCE
ALPIVVDVADHDAVERAAARVEAELGPIDVWINCAMATIFCRADQIAPADFVRATHVTYL
EEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GAVWGTLAALGRMKTRNRGVIVQVGSALAYRSIPLQAPYCGAKSALRGFTDSLRSELIHD
HHHHHHHHHHHHHHCCCCCEEEEECCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
GSRIHLTMVHLSAFNTPQFDWGRTCMHRQPQPVPPIFQPEVAADAIVWAALHHRRESWVG
CCEEEEEEEEEECCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
WPAVQAIIGTRLIPGVLDRFLARHGFDSQHTDQPLPRDRPDNLYHPVKGDHGAHGRFSDR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
AARSSIQWWLNTHRWVMAAVVMIVMALVAGWLWRSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADAKPVQSARCVVITGASAGIGRATARAFGRMAWRVGLLARGQDGLRAAASEVERSGGV
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCE
ALPIVVDVADHDAVERAAARVEAELGPIDVWINCAMATIFCRADQIAPADFVRATHVTYL
EEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GAVWGTLAALGRMKTRNRGVIVQVGSALAYRSIPLQAPYCGAKSALRGFTDSLRSELIHD
HHHHHHHHHHHHHHCCCCCEEEEECCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
GSRIHLTMVHLSAFNTPQFDWGRTCMHRQPQPVPPIFQPEVAADAIVWAALHHRRESWVG
CCEEEEEEEEEECCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
WPAVQAIIGTRLIPGVLDRFLARHGFDSQHTDQPLPRDRPDNLYHPVKGDHGAHGRFSDR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
AARSSIQWWLNTHRWVMAAVVMIVMALVAGWLWRSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]