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The map label for this gene is gbpR [H]

Identifier: 73538246

GI number: 73538246

Start: 1075919

End: 1076887

Strand: Reverse

Name: gbpR [H]

Synonym: Reut_B4418

Alternate gene names: 73538246

Gene position: 1076887-1075919 (Counterclockwise)

Preceding gene: 73538249

Following gene: 73538244

Centisome position: 39.5

GC content: 68.21

Gene sequence:

>969_bases
ATGAGTGCCAATACGCCGGCGATGCGCCAGGCACGGCTTGCCGGTCGCCTCGACCGCCTTCGCATCCGCCACTTGCGTTT
TCTGGGGCTGATCGAATCCCATGGCTCGCTGTCGGGCGCGGCCGCAGAGCTTGGGCTGAGCCAGCCTGCCGCCACCAAGA
TGCTCCAGGAGATCGAAGCGGTCTTCGGCGCCGAACTGGTCGCGCGCACGACACGCGGCGCGGCGCTGACGCCGGCGGGG
CAACTGGCGCTCGGGCGCTTGCGGATCGCCCTCAATGCGATGTCTGCCGCGATGGAGGCCATCGATGCCGCGCCGCCGGT
ACCCGTGGTGCGTCTCGGCATCCTGCCGCTGGCCGGCGTCGTCGCTTTGCCCATGCTGCTTGCGAAGATGACCTCGCGGC
CCGACTGCCCACACCTTGTGGTGCACGAATCCACGGTTGCCGGCCTGCTCGGCATGCTCGACCGCGGCGAACTCGACTGT
GTGATCGGCCGTGTCGGCAGCAGCCTCGAAGCCAGCGCAACGCGCGAGATGCGCGTGACGCCGCTCTGGGAAGAGCGGCT
GGCCATTGCCTGCGCGCTGGCCCATCCGGTCGCAAAGAAGCGGTCGCTGGGGCTTTCCGACCTGTGCGAATACGACTGGG
TGATCACGCCGCGCGGCGCCCATACGCGTACGCTGTTTGAAGCACCGTTCCTCAACGCTGGCATCGTGCCACCTCAGCCC
ACGGTCGAGTCCTTTTCGTTCCACACCAATCTCTGCATCGTCGCGCGAAGCGGCATGCTGACGATCGCGCCGGAAAGCGC
CGTGCGGCACTACGCGCAGCTGGGCATGGTGCGGCAGGTTCGGGACGGCGCCTGGTTCGCGGCCGGACGGACGGTGTTCA
TTACGCGCGATGAGGCGGCGGGGGCGCCTGGGGTGGCGGCGGTCAGTGAGGGGTTGGCCGAGTTGATGGAGGAGGCCGAT
TGGGATTGA

Upstream 100 bases:

>100_bases
GTGTTGTCTCCTTGTCATGGTCTGGAAGATGGTGTCGATTGTGGGAGTGCTGGCATTTCCTGTAAATTATTAGTTGTTAA
TCAGGTCATCACGATTTGTT

Downstream 100 bases:

>100_bases
GGTGGGCGAGCGTGGCATGGGCGCTGCTGCGCCGGCGTAGCCGGCGCAACAGCCTTTGTGTCCCGCGAATCCCGATATAC
CGCTGCGCCTGGCGATACTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MSANTPAMRQARLAGRLDRLRIRHLRFLGLIESHGSLSGAAAELGLSQPAATKMLQEIEAVFGAELVARTTRGAALTPAG
QLALGRLRIALNAMSAAMEAIDAAPPVPVVRLGILPLAGVVALPMLLAKMTSRPDCPHLVVHESTVAGLLGMLDRGELDC
VIGRVGSSLEASATREMRVTPLWEERLAIACALAHPVAKKRSLGLSDLCEYDWVITPRGAHTRTLFEAPFLNAGIVPPQP
TVESFSFHTNLCIVARSGMLTIAPESAVRHYAQLGMVRQVRDGAWFAAGRTVFITRDEAAGAPGVAAVSEGLAELMEEAD
WD

Sequences:

>Translated_322_residues
MSANTPAMRQARLAGRLDRLRIRHLRFLGLIESHGSLSGAAAELGLSQPAATKMLQEIEAVFGAELVARTTRGAALTPAG
QLALGRLRIALNAMSAAMEAIDAAPPVPVVRLGILPLAGVVALPMLLAKMTSRPDCPHLVVHESTVAGLLGMLDRGELDC
VIGRVGSSLEASATREMRVTPLWEERLAIACALAHPVAKKRSLGLSDLCEYDWVITPRGAHTRTLFEAPFLNAGIVPPQP
TVESFSFHTNLCIVARSGMLTIAPESAVRHYAQLGMVRQVRDGAWFAAGRTVFITRDEAAGAPGVAAVSEGLAELMEEAD
WD
>Mature_321_residues
SANTPAMRQARLAGRLDRLRIRHLRFLGLIESHGSLSGAAAELGLSQPAATKMLQEIEAVFGAELVARTTRGAALTPAGQ
LALGRLRIALNAMSAAMEAIDAAPPVPVVRLGILPLAGVVALPMLLAKMTSRPDCPHLVVHESTVAGLLGMLDRGELDCV
IGRVGSSLEASATREMRVTPLWEERLAIACALAHPVAKKRSLGLSDLCEYDWVITPRGAHTRTLFEAPFLNAGIVPPQPT
VESFSFHTNLCIVARSGMLTIAPESAVRHYAQLGMVRQVRDGAWFAAGRTVFITRDEAAGAPGVAAVSEGLAELMEEADW
D

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=259, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789506, Length=248, Percent_Identity=26.6129032258064, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081904, Length=255, Percent_Identity=28.6274509803922, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI157672245, Length=244, Percent_Identity=27.4590163934426, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790399, Length=194, Percent_Identity=26.8041237113402, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34244; Mature: 34113

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANTPAMRQARLAGRLDRLRIRHLRFLGLIESHGSLSGAAAELGLSQPAATKMLQEIEA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHH
VFGAELVARTTRGAALTPAGQLALGRLRIALNAMSAAMEAIDAAPPVPVVRLGILPLAGV
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
VALPMLLAKMTSRPDCPHLVVHESTVAGLLGMLDRGELDCVIGRVGSSLEASATREMRVT
HHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEECC
PLWEERLAIACALAHPVAKKRSLGLSDLCEYDWVITPRGAHTRTLFEAPFLNAGIVPPQP
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEECCCCCCCHHEEECCCCCCCCCCCCC
TVESFSFHTNLCIVARSGMLTIAPESAVRHYAQLGMVRQVRDGAWFAAGRTVFITRDEAA
CHHCCCCCCCEEEEEECCEEEECCHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCC
GAPGVAAVSEGLAELMEEADWD
CCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SANTPAMRQARLAGRLDRLRIRHLRFLGLIESHGSLSGAAAELGLSQPAATKMLQEIEA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHH
VFGAELVARTTRGAALTPAGQLALGRLRIALNAMSAAMEAIDAAPPVPVVRLGILPLAGV
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
VALPMLLAKMTSRPDCPHLVVHESTVAGLLGMLDRGELDCVIGRVGSSLEASATREMRVT
HHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEECC
PLWEERLAIACALAHPVAKKRSLGLSDLCEYDWVITPRGAHTRTLFEAPFLNAGIVPPQP
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEECCCCCCCHHEEECCCCCCCCCCCCC
TVESFSFHTNLCIVARSGMLTIAPESAVRHYAQLGMVRQVRDGAWFAAGRTVFITRDEAA
CHHCCCCCCCEEEEEECCEEEECCHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCC
GAPGVAAVSEGLAELMEEADWD
CCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]