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The map label for this gene is namA [H]

Identifier: 73538147

GI number: 73538147

Start: 973846

End: 974961

Strand: Reverse

Name: namA [H]

Synonym: Reut_B4317

Alternate gene names: 73538147

Gene position: 974961-973846 (Counterclockwise)

Preceding gene: 73538148

Following gene: 73538146

Centisome position: 35.76

GC content: 68.73

Gene sequence:

>1116_bases
ATGAGCCACCTGTTTGATCCTCTCGACATCGGCAATCTCACGCTGCCCAACCGCATCATCATTGCGCCCATGTGCCAGTA
CTCGGCGCAGGACGGCAATGCGGTCGACTGGCACATGATCCACCTCGGCTCGCTGGCGCTGTCCGGCGCGGGCATGCTGA
TCCTGGAAGCGACGGCGGTTTCCCCGGAAGGCCGGATCACGGCAGGGGACCTCGGCCTCTATTCGGACGAGAACGAAGCC
GCGCTCGGGCACGTGCTCAAGGCGATCCGCGCGCACGCGCCGATCGCCGTGGCCATTCAACTCGGGCATGCGGGGCGTAA
GGCATCGAGCCAGGTGCCATGGGAAGGCGGCCAGCAGGTCGCGCCCGATGCGCCGGGCGGCTGGCAGGCGGTTGCACCCT
CGGCGGTGCCCCATGCCGAAGGCGAGGCGCGCCCGACGGCGCTCGACCGCGCCGGCATGGACAAGGTGCGCGACGACTTC
GTCGCGGCGGCGGTGCGTGCGGTGAGGCTCGGCATCCAGGGCTTCGAGATCCATGCGGCACACGGCTATCTGTTGCACCA
GTTCCTGTCGCCGCTGGCCAATCATCGCGACGATGAATACGGTGGCAGCCTCGAAAACCGCATGCGCTTCCCGATCGAGG
TCTTCGACGCGGTGCGCGCCGCAGTGCCGGCAGACCGGCCGGTGTGGATGCGCATCTCGGCCACAGACTGGGTGCCGGGC
GGCTGGGATATCGAGGGAACGGTGGCGCTGTCGCAGGCGGTGAAGGCGCGTGGGTGCGCGGCGATCCATGTCACTACTGG
CGGGGTCTCGCCGGCGCAGGCAATCAAGCTCGGCCCGGGCTACCAGGTTCCGTATGCGCAGCGCGTGAAGGCCAAGGTGG
GCCTGCCGACCATCGCCGTGGGGCTGATCACCGAGCCGGAGCAAGCCGAGGCCATCATCACGGGCAACGAGGCCGACGCC
GTCTCGCTGGCGCGCGCGATGCTCTACGATCCGCGCTGGCCGTGGCATGCCGCAGCGAAGCTCGGGGCTAGCGTGGCGGC
GCCGAAACAGTACTGGCGTTCCCAGCCGCGCGAGTTGAAGGACCTGTTTTCGGGCGCCAACTTCGGCCAGCGCTGA

Upstream 100 bases:

>100_bases
CAAATTCCGCATCGGCCTAGAATCGAGCGGTTCACCCGTCGCATAGGGCGCCCTCTGTGCGCCGATTCTGATCTCCTGAT
CTGCAAGACAAGGTATTCGC

Downstream 100 bases:

>100_bases
ATTTGCGCTGCACCGCTTTCACTCCACAAGAAGAGGAGGGCCCATGAAACCACGTGTCACGCTGATCACGCTGGGCGTCG
ACGACCTGGAACGATCGCTG

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSHLFDPLDIGNLTLPNRIIIAPMCQYSAQDGNAVDWHMIHLGSLALSGAGMLILEATAVSPEGRITAGDLGLYSDENEA
ALGHVLKAIRAHAPIAVAIQLGHAGRKASSQVPWEGGQQVAPDAPGGWQAVAPSAVPHAEGEARPTALDRAGMDKVRDDF
VAAAVRAVRLGIQGFEIHAAHGYLLHQFLSPLANHRDDEYGGSLENRMRFPIEVFDAVRAAVPADRPVWMRISATDWVPG
GWDIEGTVALSQAVKARGCAAIHVTTGGVSPAQAIKLGPGYQVPYAQRVKAKVGLPTIAVGLITEPEQAEAIITGNEADA
VSLARAMLYDPRWPWHAAAKLGASVAAPKQYWRSQPRELKDLFSGANFGQR

Sequences:

>Translated_371_residues
MSHLFDPLDIGNLTLPNRIIIAPMCQYSAQDGNAVDWHMIHLGSLALSGAGMLILEATAVSPEGRITAGDLGLYSDENEA
ALGHVLKAIRAHAPIAVAIQLGHAGRKASSQVPWEGGQQVAPDAPGGWQAVAPSAVPHAEGEARPTALDRAGMDKVRDDF
VAAAVRAVRLGIQGFEIHAAHGYLLHQFLSPLANHRDDEYGGSLENRMRFPIEVFDAVRAAVPADRPVWMRISATDWVPG
GWDIEGTVALSQAVKARGCAAIHVTTGGVSPAQAIKLGPGYQVPYAQRVKAKVGLPTIAVGLITEPEQAEAIITGNEADA
VSLARAMLYDPRWPWHAAAKLGASVAAPKQYWRSQPRELKDLFSGANFGQR
>Mature_370_residues
SHLFDPLDIGNLTLPNRIIIAPMCQYSAQDGNAVDWHMIHLGSLALSGAGMLILEATAVSPEGRITAGDLGLYSDENEAA
LGHVLKAIRAHAPIAVAIQLGHAGRKASSQVPWEGGQQVAPDAPGGWQAVAPSAVPHAEGEARPTALDRAGMDKVRDDFV
AAAVRAVRLGIQGFEIHAAHGYLLHQFLSPLANHRDDEYGGSLENRMRFPIEVFDAVRAAVPADRPVWMRISATDWVPGG
WDIEGTVALSQAVKARGCAAIHVTTGGVSPAQAIKLGPGYQVPYAQRVKAKVGLPTIAVGLITEPEQAEAIITGNEADAV
SLARAMLYDPRWPWHAAAKLGASVAAPKQYWRSQPRELKDLFSGANFGQR

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=340, Percent_Identity=32.6470588235294, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1789463, Length=330, Percent_Identity=29.3939393939394, Blast_Score=113, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17559804, Length=301, Percent_Identity=28.9036544850498, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17564188, Length=301, Percent_Identity=26.9102990033223, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI72001454, Length=302, Percent_Identity=26.8211920529801, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17540738, Length=299, Percent_Identity=26.4214046822742, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17559802, Length=311, Percent_Identity=25.7234726688103, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17565138, Length=200, Percent_Identity=28, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17566914, Length=229, Percent_Identity=29.6943231441048, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6325086, Length=242, Percent_Identity=30.5785123966942, Blast_Score=103, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6321973, Length=246, Percent_Identity=31.7073170731707, Blast_Score=103, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 39466; Mature: 39335

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHLFDPLDIGNLTLPNRIIIAPMCQYSAQDGNAVDWHMIHLGSLALSGAGMLILEATAV
CCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCCEEEEEEEEHHHHHCCCCEEEEEEEEC
SPEGRITAGDLGLYSDENEAALGHVLKAIRAHAPIAVAIQLGHAGRKASSQVPWEGGQQV
CCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCEE
APDAPGGWQAVAPSAVPHAEGEARPTALDRAGMDKVRDDFVAAAVRAVRLGIQGFEIHAA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEH
HGYLLHQFLSPLANHRDDEYGGSLENRMRFPIEVFDAVRAAVPADRPVWMRISATDWVPG
HHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCC
GWDIEGTVALSQAVKARGCAAIHVTTGGVSPAQAIKLGPGYQVPYAQRVKAKVGLPTIAV
CCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHEEECCCCCCCCHHHHHHHHCCCCEEEE
GLITEPEQAEAIITGNEADAVSLARAMLYDPRWPWHAAAKLGASVAAPKQYWRSQPRELK
EEECCCCCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHCCHHCCCHHHHHCCCHHHH
DLFSGANFGQR
HHHCCCCCCCC
>Mature Secondary Structure 
SHLFDPLDIGNLTLPNRIIIAPMCQYSAQDGNAVDWHMIHLGSLALSGAGMLILEATAV
CCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCCEEEEEEEEHHHHHCCCCEEEEEEEEC
SPEGRITAGDLGLYSDENEAALGHVLKAIRAHAPIAVAIQLGHAGRKASSQVPWEGGQQV
CCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCEE
APDAPGGWQAVAPSAVPHAEGEARPTALDRAGMDKVRDDFVAAAVRAVRLGIQGFEIHAA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEH
HGYLLHQFLSPLANHRDDEYGGSLENRMRFPIEVFDAVRAAVPADRPVWMRISATDWVPG
HHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCC
GWDIEGTVALSQAVKARGCAAIHVTTGGVSPAQAIKLGPGYQVPYAQRVKAKVGLPTIAV
CCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHEEECCCCCCCCHHHHHHHHCCCCEEEE
GLITEPEQAEAIITGNEADAVSLARAMLYDPRWPWHAAAKLGASVAAPKQYWRSQPRELK
EEECCCCCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHCCHHCCCHHHHHCCCHHHH
DLFSGANFGQR
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA