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The map label for this gene is exuT [H]

Identifier: 73538143

GI number: 73538143

Start: 970403

End: 971698

Strand: Reverse

Name: exuT [H]

Synonym: Reut_B4313

Alternate gene names: 73538143

Gene position: 971698-970403 (Counterclockwise)

Preceding gene: 73538144

Following gene: 73538142

Centisome position: 35.64

GC content: 66.82

Gene sequence:

>1296_bases
ATGAGTGCAACGTATCAGCGGGGCCGTGCATGGGTGGTGACCGTGCTGCTATTCCTGTTCGTGGTCGTGAACTTCCTCGA
CAAGATCAGCGTGGGGCTGCTTGCTGGCCCGATGATGGACGAACTTGGTCTCACGCCGGCGCAATTCGGGCTGGTCGGCA
GCAGCTTCTTCTGGCTGTTCGCGGTGGCCGGCGTAGCCGGTGGCTTTATTGCCAACCGCGTTTCGTGCACGTTGCTGCTA
TTGTTGATGGCCGTGGCGTGGTCCCTGTTCCAGATTCCGCTGGCATGGTCATCGAGCCTGGCCGTGCTGATCGCAGCGCG
TGTACTGCTCGGCATTGCTGAGGGGCCGTCGACCGCCATTGCCATCCATGCGGCCTACAAGTGGTTCCCCGATGATCGCC
GCACGCTGCCTGTGGCGTTCTTTACGCAGGGCGGCGCTACGGGCCTGATCCTCGCGGGTATCACGATTCCATACATCACC
GCGCACTGGGGCTGGCGCGCTAATTTCTACGTACTGGCCGCGCTCGGCGCCGCGTGGGCCGTGCTGTGGCTGCTGTTTGG
TGGCGAGGGCAAGGTCGAACAGCCTTCGGCCCAGGCCACCACGCGACAGCGCGTTCCGTATCGGGCGCTGCTCGGCGATG
CCACGGTACTGGGCTGCTTCCTGCTGCGCTTTGTGGCGTACTGGAGCCTCGCGCTGTCGCTGACGTGGTTCGCGGCCTAC
CTGCAGCGCGGACTTGGTTTCGACCATGCCATGTCGGGTCGGCTGTTTGCGGCCATCATCGCGGTCAACATGCCGGTCAC
GATGGCCGTGGCGTGGTGGTCGCAGCGCATGCTGCGTCGGGGCACGCCGTCGCGCATTGCCAGGGGCCGCCTGGCCGCGC
TGATGCTCGTGGGCGCCGGGGTTTGCCTTGCGGCGCTGGTGGCGCCGGGGCTGGGCAACTGGCAGCGCGTCGCGCTGCTC
GCGGCAAGCTGCGCGCTCGCGCCCTCGATCTACTCGCTCGGGCCGGCCATGCTGGCTGAAGTGTGCCCGCCGGCGCAGCG
TGGTGCGCTGCTGTCGATCGACGCCTCGATTTCATCGATCGCCGGCATCCTAGCGCCGCTGGTGACCGGTTATCTGGTGC
AGAACGCCACCGGGGCGCATGGTTACGAGACCGGCTTCGCGGTGTGCGGCGCGTTGATGATCGTTGGCGGGTTCGGTGGC
GCCGCGCTGATCAATCCGGAGCGCTCGAAGCAGCGACTCGCCGGTCTGCAGCAGCAGGGAACCACCGTGCCAGACTCGCG
CGCGGCGCACGCCTGA

Upstream 100 bases:

>100_bases
GTGACGGCCGGCCAAGCGGTGACGCCCCGCGTGTCGCCCACAATCAGTTTGCGCAAGCCCCAGGCCGGCTCTACAAACAA
GAAAACGGAGACAAGGACGA

Downstream 100 bases:

>100_bases
CGTCAGAGATCGCGCGCTCGCCGATATACTGCAGGCTTTGCCGGGCCATGCGCCCGGGCGCTCCGGAGCGTTCACGATGA
TGCCTGCAGCTTCCAGCTGG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MSATYQRGRAWVVTVLLFLFVVVNFLDKISVGLLAGPMMDELGLTPAQFGLVGSSFFWLFAVAGVAGGFIANRVSCTLLL
LLMAVAWSLFQIPLAWSSSLAVLIAARVLLGIAEGPSTAIAIHAAYKWFPDDRRTLPVAFFTQGGATGLILAGITIPYIT
AHWGWRANFYVLAALGAAWAVLWLLFGGEGKVEQPSAQATTRQRVPYRALLGDATVLGCFLLRFVAYWSLALSLTWFAAY
LQRGLGFDHAMSGRLFAAIIAVNMPVTMAVAWWSQRMLRRGTPSRIARGRLAALMLVGAGVCLAALVAPGLGNWQRVALL
AASCALAPSIYSLGPAMLAEVCPPAQRGALLSIDASISSIAGILAPLVTGYLVQNATGAHGYETGFAVCGALMIVGGFGG
AALINPERSKQRLAGLQQQGTTVPDSRAAHA

Sequences:

>Translated_431_residues
MSATYQRGRAWVVTVLLFLFVVVNFLDKISVGLLAGPMMDELGLTPAQFGLVGSSFFWLFAVAGVAGGFIANRVSCTLLL
LLMAVAWSLFQIPLAWSSSLAVLIAARVLLGIAEGPSTAIAIHAAYKWFPDDRRTLPVAFFTQGGATGLILAGITIPYIT
AHWGWRANFYVLAALGAAWAVLWLLFGGEGKVEQPSAQATTRQRVPYRALLGDATVLGCFLLRFVAYWSLALSLTWFAAY
LQRGLGFDHAMSGRLFAAIIAVNMPVTMAVAWWSQRMLRRGTPSRIARGRLAALMLVGAGVCLAALVAPGLGNWQRVALL
AASCALAPSIYSLGPAMLAEVCPPAQRGALLSIDASISSIAGILAPLVTGYLVQNATGAHGYETGFAVCGALMIVGGFGG
AALINPERSKQRLAGLQQQGTTVPDSRAAHA
>Mature_430_residues
SATYQRGRAWVVTVLLFLFVVVNFLDKISVGLLAGPMMDELGLTPAQFGLVGSSFFWLFAVAGVAGGFIANRVSCTLLLL
LMAVAWSLFQIPLAWSSSLAVLIAARVLLGIAEGPSTAIAIHAAYKWFPDDRRTLPVAFFTQGGATGLILAGITIPYITA
HWGWRANFYVLAALGAAWAVLWLLFGGEGKVEQPSAQATTRQRVPYRALLGDATVLGCFLLRFVAYWSLALSLTWFAAYL
QRGLGFDHAMSGRLFAAIIAVNMPVTMAVAWWSQRMLRRGTPSRIARGRLAALMLVGAGVCLAALVAPGLGNWQRVALLA
ASCALAPSIYSLGPAMLAEVCPPAQRGALLSIDASISSIAGILAPLVTGYLVQNATGAHGYETGFAVCGALMIVGGFGGA
ALINPERSKQRLAGLQQQGTTVPDSRAAHA

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9966811, Length=374, Percent_Identity=23.7967914438503, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI9945322, Length=360, Percent_Identity=23.8888888888889, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI21322234, Length=399, Percent_Identity=22.3057644110276, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI87082320, Length=410, Percent_Identity=22.4390243902439, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1789152, Length=409, Percent_Identity=22.4938875305623, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789515, Length=424, Percent_Identity=22.6415094339623, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI2367379, Length=414, Percent_Identity=23.6714975845411, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI2367193, Length=257, Percent_Identity=21.7898832684825, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24648416, Length=380, Percent_Identity=25.2631578947368, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21356189, Length=380, Percent_Identity=25.2631578947368, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24658658, Length=470, Percent_Identity=23.8297872340426, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24654215, Length=428, Percent_Identity=22.8971962616822, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19922400, Length=427, Percent_Identity=22.9508196721311, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI45550364, Length=426, Percent_Identity=23.2394366197183, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24583789, Length=355, Percent_Identity=23.0985915492958, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19920686, Length=402, Percent_Identity=21.1442786069652, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550460, Length=402, Percent_Identity=21.6417910447761, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24655255, Length=402, Percent_Identity=21.6417910447761, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45510; Mature: 45379

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATYQRGRAWVVTVLLFLFVVVNFLDKISVGLLAGPMMDELGLTPAQFGLVGSSFFWLF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHH
AVAGVAGGFIANRVSCTLLLLLMAVAWSLFQIPLAWSSSLAVLIAARVLLGIAEGPSTAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCHHHHHHHHHHHHHHHCCCCCCEE
AIHAAYKWFPDDRRTLPVAFFTQGGATGLILAGITIPYITAHWGWRANFYVLAALGAAWA
EEEEEEEECCCCCCEEEEEEEECCCCCEEEEECCHHHHEEECCCCCCCHHHHHHHHHHHH
VLWLLFGGEGKVEQPSAQATTRQRVPYRALLGDATVLGCFLLRFVAYWSLALSLTWFAAY
HHHHHCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQRGLGFDHAMSGRLFAAIIAVNMPVTMAVAWWSQRMLRRGTPSRIARGRLAALMLVGAG
HHHCCCCCHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VCLAALVAPGLGNWQRVALLAASCALAPSIYSLGPAMLAEVCPPAQRGALLSIDASISSI
HHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHCCHHHHHHHCCCCCCCEEEEECCHHHHH
AGILAPLVTGYLVQNATGAHGYETGFAVCGALMIVGGFGGAALINPERSKQRLAGLQQQG
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHCC
TTVPDSRAAHA
CCCCCCCCCCC
>Mature Secondary Structure 
SATYQRGRAWVVTVLLFLFVVVNFLDKISVGLLAGPMMDELGLTPAQFGLVGSSFFWLF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHH
AVAGVAGGFIANRVSCTLLLLLMAVAWSLFQIPLAWSSSLAVLIAARVLLGIAEGPSTAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCHHHHHHHHHHHHHHHCCCCCCEE
AIHAAYKWFPDDRRTLPVAFFTQGGATGLILAGITIPYITAHWGWRANFYVLAALGAAWA
EEEEEEEECCCCCCEEEEEEEECCCCCEEEEECCHHHHEEECCCCCCCHHHHHHHHHHHH
VLWLLFGGEGKVEQPSAQATTRQRVPYRALLGDATVLGCFLLRFVAYWSLALSLTWFAAY
HHHHHCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQRGLGFDHAMSGRLFAAIIAVNMPVTMAVAWWSQRMLRRGTPSRIARGRLAALMLVGAG
HHHCCCCCHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VCLAALVAPGLGNWQRVALLAASCALAPSIYSLGPAMLAEVCPPAQRGALLSIDASISSI
HHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHCCHHHHHHHCCCCCCCEEEEECCHHHHH
AGILAPLVTGYLVQNATGAHGYETGFAVCGALMIVGGFGGAALINPERSKQRLAGLQQQG
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHCC
TTVPDSRAAHA
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]