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The map label for this gene is yngJ [H]

Identifier: 73537985

GI number: 73537985

Start: 793538

End: 794770

Strand: Direct

Name: yngJ [H]

Synonym: Reut_B4154

Alternate gene names: 73537985

Gene position: 793538-794770 (Clockwise)

Preceding gene: 73537984

Following gene: 73537986

Centisome position: 29.11

GC content: 64.4

Gene sequence:

>1233_bases
ATGAACTTTGACATCCCCAGCGAATGGGTCGAGTTCGGCGACGCCCTCATCAAGTTCGTTGACCGGGAAGTGGCAGGGCT
CGAGAACGAGCATCGCGCGTTGCTCGGCGGCGAACGCACCGTCTACACCGAAGACGGCCGCTATGCGCCCGAAGTCCTCG
CGCTGCGCCGCAAGGTGCGCATGCGTTCGGCTGAACTGGGCTTTTACACGGCGCTGTCGGCGGAATCGCTCGGTGGCGAG
GGGTTGGGCCCGCAGGCGGCGGTCTATATCCAGGAGCGCCTGAACGCCCATTGCGGGCCAGAGCGCCACTTGGTCCAGAC
CGTGGTGCTTCCCTCTCCGTTCACCAATGGTCTCTCTCCGGTTCTGAAGCACCTCGATCCGGCGGTGCTGAATACGGTGC
GTGACGAGCTGGCCAGCGGCGATAAGACCATGTGCTTCGGCCTGTCCGAGCCAGACGCCGGCTCCGACGTGTTTGGCATG
CGCACGCGCGCGGTCCGCGATGGGGATCAGTGGGTCCTCAACGGCACGAAGCAGTGGATCACCAACGCGCCGTATGCCGA
CTACGCCATGGTGTTCGCGGTTACGGATGAAGAGAAGGCACGCACGCACAAGGGCGGCATCACCGGCTTCTTCCTGCCTG
CCAATACACCGGGTTTCTCCGTGCCGAGCGTGATTCCGACCATGGGCCACCTTGGCGCCGATATCGGCATCATCTCGCTG
GAAAACGTGCGCGTGCCGGACACCCACCGGCTTGGTCCGGTCGACCGTGGCCTGTCGGTCGCGCTGGACGGCGTGAACGC
CGGGCGCCTGAGCATGGCGGCGAGTTGCCTTGGACTGGCCGAATGGGCGCTGCAGCAAGCGGTGGACTACGCCAAGGTGC
GCAAGACATTTGGCCAGCCGATCGGCGAGCATCAGGCCGTGCAGATCATGCTGGCCGAATGCGCCATGGATATCTACGCC
ACCAAGTCGATGGTGCGCCATTGCGCGTGGCTGGTGGACAACAACCTGCCGGCGACCAAGGAAGTGTCTATTGTCAAGGC
ATCGGCGACCGAGATGACGGGCCGGGTCTTCGACCGTGCCATGCAGGTCCACGGCGGCATGGGCCTTACCAATGAGCTTC
GGCTGGAGGCCGGCTACCGATTTGCACGGACCATGCGTATTCCGGACGGCACCTCCGAGATCCAGCGCCGCACCATTGCG
CGCCGGCTGCTCGACGGCGATATGGCATTCTGA

Upstream 100 bases:

>100_bases
GTGCGGGTCAGCTTTTCGCCGAGCGAGGGCGGAGCGCCTGTGCCGACGTTCGCACCGGCCTGACGGGTCATACAGAAAAT
AGACATAGGAGACTTGCACC

Downstream 100 bases:

>100_bases
ACCCGCATCCGACTTTCCCTGCCTGCAATGACCATGACTCCCTACCTGCCCGGCGCCTGCGACGCTGTGGCCTACCCAAG
CGGAACGTTGTCCGTGGACA

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MNFDIPSEWVEFGDALIKFVDREVAGLENEHRALLGGERTVYTEDGRYAPEVLALRRKVRMRSAELGFYTALSAESLGGE
GLGPQAAVYIQERLNAHCGPERHLVQTVVLPSPFTNGLSPVLKHLDPAVLNTVRDELASGDKTMCFGLSEPDAGSDVFGM
RTRAVRDGDQWVLNGTKQWITNAPYADYAMVFAVTDEEKARTHKGGITGFFLPANTPGFSVPSVIPTMGHLGADIGIISL
ENVRVPDTHRLGPVDRGLSVALDGVNAGRLSMAASCLGLAEWALQQAVDYAKVRKTFGQPIGEHQAVQIMLAECAMDIYA
TKSMVRHCAWLVDNNLPATKEVSIVKASATEMTGRVFDRAMQVHGGMGLTNELRLEAGYRFARTMRIPDGTSEIQRRTIA
RRLLDGDMAF

Sequences:

>Translated_410_residues
MNFDIPSEWVEFGDALIKFVDREVAGLENEHRALLGGERTVYTEDGRYAPEVLALRRKVRMRSAELGFYTALSAESLGGE
GLGPQAAVYIQERLNAHCGPERHLVQTVVLPSPFTNGLSPVLKHLDPAVLNTVRDELASGDKTMCFGLSEPDAGSDVFGM
RTRAVRDGDQWVLNGTKQWITNAPYADYAMVFAVTDEEKARTHKGGITGFFLPANTPGFSVPSVIPTMGHLGADIGIISL
ENVRVPDTHRLGPVDRGLSVALDGVNAGRLSMAASCLGLAEWALQQAVDYAKVRKTFGQPIGEHQAVQIMLAECAMDIYA
TKSMVRHCAWLVDNNLPATKEVSIVKASATEMTGRVFDRAMQVHGGMGLTNELRLEAGYRFARTMRIPDGTSEIQRRTIA
RRLLDGDMAF
>Mature_410_residues
MNFDIPSEWVEFGDALIKFVDREVAGLENEHRALLGGERTVYTEDGRYAPEVLALRRKVRMRSAELGFYTALSAESLGGE
GLGPQAAVYIQERLNAHCGPERHLVQTVVLPSPFTNGLSPVLKHLDPAVLNTVRDELASGDKTMCFGLSEPDAGSDVFGM
RTRAVRDGDQWVLNGTKQWITNAPYADYAMVFAVTDEEKARTHKGGITGFFLPANTPGFSVPSVIPTMGHLGADIGIISL
ENVRVPDTHRLGPVDRGLSVALDGVNAGRLSMAASCLGLAEWALQQAVDYAKVRKTFGQPIGEHQAVQIMLAECAMDIYA
TKSMVRHCAWLVDNNLPATKEVSIVKASATEMTGRVFDRAMQVHGGMGLTNELRLEAGYRFARTMRIPDGTSEIQRRTIA
RRLLDGDMAF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=339, Percent_Identity=36.8731563421829, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI4557231, Length=405, Percent_Identity=31.1111111111111, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI187960098, Length=405, Percent_Identity=31.1111111111111, Blast_Score=179, Evalue=6e-45,
Organism=Homo sapiens, GI4501859, Length=263, Percent_Identity=33.4600760456274, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI226958412, Length=392, Percent_Identity=28.5714285714286, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI226958414, Length=266, Percent_Identity=32.7067669172932, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI4501857, Length=352, Percent_Identity=28.9772727272727, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI21361497, Length=270, Percent_Identity=32.2222222222222, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI7656849, Length=348, Percent_Identity=27.2988505747126, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI76496475, Length=346, Percent_Identity=32.6589595375723, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI4557235, Length=346, Percent_Identity=32.6589595375723, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI38505218, Length=274, Percent_Identity=29.5620437956204, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI211971008, Length=273, Percent_Identity=29.3040293040293, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI48976061, Length=273, Percent_Identity=29.3040293040293, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI7669494, Length=272, Percent_Identity=31.25, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI4503943, Length=280, Percent_Identity=31.4285714285714, Blast_Score=112, Evalue=7e-25,
Organism=Escherichia coli, GI87081958, Length=273, Percent_Identity=30.03663003663, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1786223, Length=344, Percent_Identity=27.6162790697674, Blast_Score=112, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17569725, Length=404, Percent_Identity=29.2079207920792, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17570075, Length=404, Percent_Identity=28.7128712871287, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17534899, Length=339, Percent_Identity=32.1533923303835, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17508101, Length=256, Percent_Identity=34.765625, Blast_Score=160, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI17538396, Length=268, Percent_Identity=35.8208955223881, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17533517, Length=352, Percent_Identity=30.1136363636364, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71985184, Length=348, Percent_Identity=31.8965517241379, Blast_Score=147, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI17506239, Length=267, Percent_Identity=32.9588014981273, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71990804, Length=205, Percent_Identity=33.6585365853659, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17534353, Length=268, Percent_Identity=29.1044776119403, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71985192, Length=283, Percent_Identity=30.0353356890459, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17505929, Length=369, Percent_Identity=27.9132791327913, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17551932, Length=342, Percent_Identity=26.9005847953216, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17531909, Length=242, Percent_Identity=31.404958677686, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI32563615, Length=180, Percent_Identity=32.2222222222222, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71982178, Length=190, Percent_Identity=33.1578947368421, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17562446, Length=358, Percent_Identity=26.536312849162, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17531913, Length=175, Percent_Identity=29.1428571428571, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356377, Length=358, Percent_Identity=34.6368715083799, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24646207, Length=343, Percent_Identity=34.402332361516, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24660351, Length=260, Percent_Identity=36.9230769230769, Blast_Score=174, Evalue=8e-44,
Organism=Drosophila melanogaster, GI24666513, Length=256, Percent_Identity=33.984375, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI21355753, Length=268, Percent_Identity=35.8208955223881, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI281363737, Length=265, Percent_Identity=33.9622641509434, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI19920834, Length=272, Percent_Identity=30.1470588235294, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 44791; Mature: 44791

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFDIPSEWVEFGDALIKFVDREVAGLENEHRALLGGERTVYTEDGRYAPEVLALRRKVR
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEECCCCCCHHHHHHHHHHH
MRSAELGFYTALSAESLGGEGLGPQAAVYIQERLNAHCGPERHLVQTVVLPSPFTNGLSP
HHHHCCCEEEEECHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHEEEECCCCCCCCHHH
VLKHLDPAVLNTVRDELASGDKTMCFGLSEPDAGSDVFGMRTRAVRDGDQWVLNGTKQWI
HHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCEEEECCCHHHH
TNAPYADYAMVFAVTDEEKARTHKGGITGFFLPANTPGFSVPSVIPTMGHLGADIGIISL
CCCCCCCEEEEEEEECCHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEE
ENVRVPDTHRLGPVDRGLSVALDGVNAGRLSMAASCLGLAEWALQQAVDYAKVRKTFGQP
CCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IGEHQAVQIMLAECAMDIYATKSMVRHCAWLVDNNLPATKEVSIVKASATEMTGRVFDRA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHH
MQVHGGMGLTNELRLEAGYRFARTMRIPDGTSEIQRRTIARRLLDGDMAF
HHHHCCCCCCHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNFDIPSEWVEFGDALIKFVDREVAGLENEHRALLGGERTVYTEDGRYAPEVLALRRKVR
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEECCCCCCHHHHHHHHHHH
MRSAELGFYTALSAESLGGEGLGPQAAVYIQERLNAHCGPERHLVQTVVLPSPFTNGLSP
HHHHCCCEEEEECHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHEEEECCCCCCCCHHH
VLKHLDPAVLNTVRDELASGDKTMCFGLSEPDAGSDVFGMRTRAVRDGDQWVLNGTKQWI
HHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCEEEECCCHHHH
TNAPYADYAMVFAVTDEEKARTHKGGITGFFLPANTPGFSVPSVIPTMGHLGADIGIISL
CCCCCCCEEEEEEEECCHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEE
ENVRVPDTHRLGPVDRGLSVALDGVNAGRLSMAASCLGLAEWALQQAVDYAKVRKTFGQP
CCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IGEHQAVQIMLAECAMDIYATKSMVRHCAWLVDNNLPATKEVSIVKASATEMTGRVFDRA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHH
MQVHGGMGLTNELRLEAGYRFARTMRIPDGTSEIQRRTIARRLLDGDMAF
HHHHCCCCCCHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]