BacMap

Definition	Ralstonia eutropha JMP134 chromosome chromosome 2, complete sequence.
Accession	NC_007348
Length	2,726,152

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The map label for this gene is phbB [H]

Identifier: 73537958

GI number: 73537958

Start: 766273

End: 767016

Strand: Direct

Name: phbB [H]

Synonym: Reut_B4127

Alternate gene names: 73537958

Gene position: 766273-767016 (Clockwise)

Preceding gene: 73537957

Following gene: 73537959

Centisome position: 28.11

GC content: 59.95

Gene sequence:

>744_bases
ATGACAAAGCGAATTGCGCTGGTAACCGGTGGCATGGGCGGCATCGGCGAAGCGATCAGCACCAGGCTGTACGACGCAGG
CAATACGGTGGTGGTCACTCATTCGCCAGGCAATGAAGGCGTGGCGGACTGGCTGGCCCGCATGGCGGAAACTGGGCGCC
GTTTTGCCGCCTACAGTGTTGACGTGTCGGACTACGCGTCGTGCCAGGCGTGCGTGGCGCGAATCCAGGAGGAAATCGGG
CCGGTCGATATCCTGATCAATAATGCCGGCATCACGCGCGACAGCAGCTTCAAGAAGCTTGATAAGGTCAACTGGGAAGC
GGTAGTTCGCACCAATCTCGATTCCCTGTTCAATATGACCAAGCAGGTCTGCGATGGCATGGTCGAGCGAGGTTGGGGCC
GCATTGTCAATGTGTCGTCCGTCATCGGGTCCAAAGGTGGATTCGGCCAGACCAATTACGCGGCGGCCAAGGCGGGCGTG
CATGGGTTCACCAAGGCACTTGCACTGGAGGTTGCGAAGCGAGGCGTCACGGTCAATACGGTGTCGCCGGGCTATGTCGC
CACCAAGATGGTCATGGCCGTGCCGCAGGAGATTCTGGATACCAATGTGCTTCCGCAGATTCCCGTGGGGCGACTGGGCC
AGCCAGACGAAATTGCCGCGCTGGTCCAATACCTGTGTTCCGCCGAGGCGGGTTTCGTCACCGGCGCCAATATCGCCATC
AATGGCGGACAGCACATGCAATGA

Upstream 100 bases:

>100_bases
ACACCGCCTGGCGCCGATGGTCGATTGGCCATAGGCGCCAGGCCGGTCAATTGGGCAAATCAGCCCTGGCAGACAAAGAC
AGGACAGGAGACTTTCGATC

Downstream 100 bases:

>100_bases
ACGCGCATAATGAGTGGTAGGACAATAGCCGGGCAGCGTACTCGCGGGCGCGAACGCGCCCGGCTGCTGCTTGAGGAAAT
GGCAGGACCGCATGGATATG

Product: acetoacetyl-CoA reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MTKRIALVTGGMGGIGEAISTRLYDAGNTVVVTHSPGNEGVADWLARMAETGRRFAAYSVDVSDYASCQACVARIQEEIG
PVDILINNAGITRDSSFKKLDKVNWEAVVRTNLDSLFNMTKQVCDGMVERGWGRIVNVSSVIGSKGGFGQTNYAAAKAGV
HGFTKALALEVAKRGVTVNTVSPGYVATKMVMAVPQEILDTNVLPQIPVGRLGQPDEIAALVQYLCSAEAGFVTGANIAI
NGGQHMQ

Sequences:

>Translated_247_residues
MTKRIALVTGGMGGIGEAISTRLYDAGNTVVVTHSPGNEGVADWLARMAETGRRFAAYSVDVSDYASCQACVARIQEEIG
PVDILINNAGITRDSSFKKLDKVNWEAVVRTNLDSLFNMTKQVCDGMVERGWGRIVNVSSVIGSKGGFGQTNYAAAKAGV
HGFTKALALEVAKRGVTVNTVSPGYVATKMVMAVPQEILDTNVLPQIPVGRLGQPDEIAALVQYLCSAEAGFVTGANIAI
NGGQHMQ
>Mature_246_residues
TKRIALVTGGMGGIGEAISTRLYDAGNTVVVTHSPGNEGVADWLARMAETGRRFAAYSVDVSDYASCQACVARIQEEIGP
VDILINNAGITRDSSFKKLDKVNWEAVVRTNLDSLFNMTKQVCDGMVERGWGRIVNVSSVIGSKGGFGQTNYAAAKAGVH
GFTKALALEVAKRGVTVNTVSPGYVATKMVMAVPQEILDTNVLPQIPVGRLGQPDEIAALVQYLCSAEAGFVTGANIAIN
GGQHMQ

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=256, Percent_Identity=36.328125, Blast_Score=154, Evalue=7e-38,
Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=32.9218106995885, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=30.5555555555556, Blast_Score=111, Evalue=6e-25,
Organism=Homo sapiens, GI4504505, Length=235, Percent_Identity=32.3404255319149, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=30.2040816326531, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI4758504, Length=256, Percent_Identity=30.46875, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=31.8548387096774, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=29.7959183673469, Blast_Score=94, Evalue=8e-20,
Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=28.2786885245902, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI66933014, Length=178, Percent_Identity=30.8988764044944, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI4503817, Length=183, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI59889578, Length=193, Percent_Identity=30.0518134715026, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI4503301, Length=201, Percent_Identity=28.3582089552239, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=27.3092369477912, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI83715985, Length=256, Percent_Identity=28.90625, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=30, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI7657478, Length=190, Percent_Identity=30, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI20149619, Length=191, Percent_Identity=28.7958115183246, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI7706318, Length=196, Percent_Identity=28.0612244897959, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI40807363, Length=192, Percent_Identity=27.6041666666667, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI210032110, Length=187, Percent_Identity=27.807486631016, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=29.4736842105263, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI226371731, Length=191, Percent_Identity=29.8429319371728, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI157739938, Length=196, Percent_Identity=27.5510204081633, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI109715829, Length=245, Percent_Identity=27.7551020408163, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI142976729, Length=215, Percent_Identity=26.5116279069767, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=42.4489795918367, Blast_Score=195, Evalue=2e-51,
Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=37.109375, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=30.7377049180328, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1790717, Length=238, Percent_Identity=30.2521008403361, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=29.4605809128631, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI87082160, Length=243, Percent_Identity=27.9835390946502, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=32.6530612244898, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=28.740157480315, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1787905, Length=242, Percent_Identity=27.6859504132231, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=32.3770491803279, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=28.6290322580645, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787820, Length=185, Percent_Identity=32.972972972973, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=25.390625, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1787526, Length=250, Percent_Identity=27.6, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=40.650406504065, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17555706, Length=257, Percent_Identity=38.5214007782101, Blast_Score=158, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=31.5789473684211, Blast_Score=111, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17568967, Length=235, Percent_Identity=33.1914893617021, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=30.6772908366534, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17538182, Length=256, Percent_Identity=32.03125, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=29.1666666666667, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193203117, Length=189, Percent_Identity=33.8624338624339, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193203115, Length=189, Percent_Identity=33.8624338624339, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=254, Percent_Identity=26.7716535433071, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=28.2442748091603, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17562990, Length=254, Percent_Identity=26.3779527559055, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=29.7709923664122, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=25.8555133079848, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=26.5151515151515, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=271, Percent_Identity=27.3062730627306, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=256, Percent_Identity=26.171875, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=260, Percent_Identity=28.0769230769231, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=28.2722513089005, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=29.2, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=254, Percent_Identity=26.3779527559055, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=253, Percent_Identity=27.6679841897233, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=28.1124497991968, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=28.8617886178862, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=27.7153558052434, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=193, Percent_Identity=27.979274611399, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=263, Percent_Identity=27.3764258555133, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508651, Length=255, Percent_Identity=26.2745098039216, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=275, Percent_Identity=26.1818181818182, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=269, Percent_Identity=26.0223048327138, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=24.9056603773585, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=274, Percent_Identity=24.4525547445255, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=25.2873563218391, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=213, Percent_Identity=25.8215962441315, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=229, Percent_Identity=33.1877729257642, Blast_Score=102, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6324126, Length=244, Percent_Identity=27.8688524590164, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=37.5510204081633, Blast_Score=141, Evalue=4e-34,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=33.8645418326693, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI21357041, Length=256, Percent_Identity=31.640625, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24643142, Length=251, Percent_Identity=29.8804780876494, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=30.1204819277108, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=30.8, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=29.3388429752066, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI18859837, Length=231, Percent_Identity=33.7662337662338, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=29.296875, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24644337, Length=184, Percent_Identity=33.695652173913, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21355631, Length=169, Percent_Identity=31.9526627218935, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=30.4123711340206, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24581726, Length=155, Percent_Identity=32.258064516129, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24665243, Length=199, Percent_Identity=31.1557788944724, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI161076933, Length=196, Percent_Identity=32.6530612244898, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI221331218, Length=199, Percent_Identity=31.1557788944724, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24584748, Length=196, Percent_Identity=32.6530612244898, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI116007236, Length=234, Percent_Identity=28.2051282051282, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24665247, Length=198, Percent_Identity=30.8080808080808, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI221331216, Length=198, Percent_Identity=30.8080808080808, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI28574402, Length=196, Percent_Identity=30.6122448979592, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584744, Length=196, Percent_Identity=30.6122448979592, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24649181, Length=188, Percent_Identity=27.6595744680851, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641232, Length=207, Percent_Identity=29.4685990338164, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI78706930, Length=222, Percent_Identity=28.3783783783784, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI78706928, Length=222, Percent_Identity=28.3783783783784, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI78706926, Length=222, Percent_Identity=28.3783783783784, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI78706924, Length=222, Percent_Identity=28.3783783783784, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI78706922, Length=222, Percent_Identity=28.3783783783784, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011283
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.36 [H]

Molecular weight: Translated: 26093; Mature: 25962

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRIALVTGGMGGIGEAISTRLYDAGNTVVVTHSPGNEGVADWLARMAETGRRFAAYSV
CCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEE
DVSDYASCQACVARIQEEIGPVDILINNAGITRDSSFKKLDKVNWEAVVRTNLDSLFNMT
CHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHCCHHHHHHHCHHHHHHHH
KQVCDGMVERGWGRIVNVSSVIGSKGGFGQTNYAAAKAGVHGFTKALALEVAKRGVTVNT
HHHHHHHHHCCCCCEEEHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEE
VSPGYVATKMVMAVPQEILDTNVLPQIPVGRLGQPDEIAALVQYLCSAEAGFVTGANIAI
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCEEEE
NGGQHMQ
CCCCCCC
>Mature Secondary Structure 
TKRIALVTGGMGGIGEAISTRLYDAGNTVVVTHSPGNEGVADWLARMAETGRRFAAYSV
CCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEE
DVSDYASCQACVARIQEEIGPVDILINNAGITRDSSFKKLDKVNWEAVVRTNLDSLFNMT
CHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHCCHHHHHHHCHHHHHHHH
KQVCDGMVERGWGRIVNVSSVIGSKGGFGQTNYAAAKAGVHGFTKALALEVAKRGVTVNT
HHHHHHHHHCCCCCEEEHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEE
VSPGYVATKMVMAVPQEILDTNVLPQIPVGRLGQPDEIAALVQYLCSAEAGFVTGANIAI
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCEEEE
NGGQHMQ
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2670935 [H]