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The map label for this gene is rpfG [H]

Identifier: 73537901

GI number: 73537901

Start: 706172

End: 707305

Strand: Direct

Name: rpfG [H]

Synonym: Reut_B4068

Alternate gene names: 73537901

Gene position: 706172-707305 (Clockwise)

Preceding gene: 73537900

Following gene: 73537902

Centisome position: 25.9

GC content: 63.84

Gene sequence:

>1134_bases
ATGAGCGCCGACAGCCCAGAGCAGCGACCAACCGTACTCGTCGTCGACGACATTCCGGAAAACATTGCCGCCATGGTGGC
AATGCTGCAGGACCAATACCGTGTGCGCGTAGCCACGCGCGGCGCCAAGGCGCTGCAACTAGCCGCGTCGTCGGCGCCGG
ACCTGATCCTGCTGGACGTTTCGATGCCCGAGATGGACGGCTATGAAACGTGCCGCCATCTGAAGGCCAATCCCGCTACG
GCCCATGTGCCGGTCATCTTCCTGACCGCACGCACGGATGAACTCGACGAAGCGCGCGGCTTCGAGGTCGGTGCCGTGGA
CTACATCATGAAGCCGGTGAGCCCGCCGGTGGCGCGCGCACGCATTGCCAGCCAGCTCGCGCTCAAGCAGGCGCACGATT
TCTTGCGTGACCGCTCGGCTTATCTCGAAGCGGAGGTGCAGCGGCGCACGCGCGAGATTACCCAGATCGAGGATGCCACC
ATCATTGCGCTGGCGGCACTGGCCGAAACCCGCGACAACGAGACCGGCAACCATATCCGCCGGACCCAGCATTACGTGAG
GGCCCTGGCGCGCGCGTTGCGCGATGACCCGCGCTTCAGCGCGCAACTCGACGACAGGACAATCGACCTGCTGTTCAAGT
CGGCGCCGCTGCACGATATTGGCAAAGTCGGCATTCCGGACCGCATCCTGCTCAAGCCCGGCAAGCTGACCGCGGAAGAG
TTCGAAATCATGAAGTCGCACACCATGCTGGGGCGCGACGCCATTGCCGACGCCGAAGCCCAGTGCGGCACGCGCAACTC
CTTCCTGCGCTACGCGCGGGAGATCGCACACTATCACCATGAAAAGTGGGATGGCACCGGCTATCCGGAAGGACTTGCCG
GCGATGACATCCCCGTAGCGGCGCGCCTGATGGCGCTTGCCGATGTCTATGACGCGCTGATTTCCCGTCGCGTCTACAAG
CCGGCCTTTTCGCATGAGGAGTCCGTGCGCATCATCATGGAAGGCCGCGGCCGGCATTTCGATCCCGGCATGGTCGACGC
CTTCCACAGCATCGCCGACGAATTCCACGCCATTGCCCTGCGCTTTGCCGATCCTGAACACGAGCCGCAGCGCGACTTGT
TGCCCGCCATCTGA

Upstream 100 bases:

>100_bases
CCTGCGGTGTGGCAGCGCACCCATGGGCGCCTGGTTCCTGAATCCGGTGCCGGTCCGCTTCGCATGCCAGCGGGCGGCCA
GCCAACCTTAAGCATTGAAA

Downstream 100 bases:

>100_bases
ATGATTTCCAAGCCCAATCCACCCGCAGGCTTCTGGCTGCGCAGCTCCCTGCTTGCCTACGGCGCCTTGCTGATCCTCGC
GGTCTGGCTCGTGGCGTTTG

Product: response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MSADSPEQRPTVLVVDDIPENIAAMVAMLQDQYRVRVATRGAKALQLAASSAPDLILLDVSMPEMDGYETCRHLKANPAT
AHVPVIFLTARTDELDEARGFEVGAVDYIMKPVSPPVARARIASQLALKQAHDFLRDRSAYLEAEVQRRTREITQIEDAT
IIALAALAETRDNETGNHIRRTQHYVRALARALRDDPRFSAQLDDRTIDLLFKSAPLHDIGKVGIPDRILLKPGKLTAEE
FEIMKSHTMLGRDAIADAEAQCGTRNSFLRYAREIAHYHHEKWDGTGYPEGLAGDDIPVAARLMALADVYDALISRRVYK
PAFSHEESVRIIMEGRGRHFDPGMVDAFHSIADEFHAIALRFADPEHEPQRDLLPAI

Sequences:

>Translated_377_residues
MSADSPEQRPTVLVVDDIPENIAAMVAMLQDQYRVRVATRGAKALQLAASSAPDLILLDVSMPEMDGYETCRHLKANPAT
AHVPVIFLTARTDELDEARGFEVGAVDYIMKPVSPPVARARIASQLALKQAHDFLRDRSAYLEAEVQRRTREITQIEDAT
IIALAALAETRDNETGNHIRRTQHYVRALARALRDDPRFSAQLDDRTIDLLFKSAPLHDIGKVGIPDRILLKPGKLTAEE
FEIMKSHTMLGRDAIADAEAQCGTRNSFLRYAREIAHYHHEKWDGTGYPEGLAGDDIPVAARLMALADVYDALISRRVYK
PAFSHEESVRIIMEGRGRHFDPGMVDAFHSIADEFHAIALRFADPEHEPQRDLLPAI
>Mature_376_residues
SADSPEQRPTVLVVDDIPENIAAMVAMLQDQYRVRVATRGAKALQLAASSAPDLILLDVSMPEMDGYETCRHLKANPATA
HVPVIFLTARTDELDEARGFEVGAVDYIMKPVSPPVARARIASQLALKQAHDFLRDRSAYLEAEVQRRTREITQIEDATI
IALAALAETRDNETGNHIRRTQHYVRALARALRDDPRFSAQLDDRTIDLLFKSAPLHDIGKVGIPDRILLKPGKLTAEEF
EIMKSHTMLGRDAIADAEAQCGTRNSFLRYAREIAHYHHEKWDGTGYPEGLAGDDIPVAARLMALADVYDALISRRVYKP
AFSHEESVRIIMEGRGRHFDPGMVDAFHSIADEFHAIALRFADPEHEPQRDLLPAI

Specific function: Positively regulates the synthesis of extracellular enzymes and extracellular polysaccharides. The cell-cell signaling system encoded by rpf genes is required for full virulence and is implicated in regulation of the formation and dispersal of biofilms [H

COG id: COG3437

COG function: function code KT; Response regulator containing a CheY-like receiver domain and an HD-GYP domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=121, Percent_Identity=42.9752066115703, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788394, Length=121, Percent_Identity=33.8842975206612, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786599, Length=116, Percent_Identity=37.0689655172414, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790863, Length=109, Percent_Identity=33.0275229357798, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790437, Length=104, Percent_Identity=37.5, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789149, Length=104, Percent_Identity=34.6153846153846, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789809, Length=124, Percent_Identity=33.8709677419355, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR003607
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 42095; Mature: 41964

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADSPEQRPTVLVVDDIPENIAAMVAMLQDQYRVRVATRGAKALQLAASSAPDLILLDV
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHEEEEECCCCHHHHHHHCCCCCEEEEEC
SMPEMDGYETCRHLKANPATAHVPVIFLTARTDELDEARGFEVGAVDYIMKPVSPPVARA
CCCCCCHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHCCCCCCHHHHHHCCCCCHHHHH
RIASQLALKQAHDFLRDRSAYLEAEVQRRTREITQIEDATIIALAALAETRDNETGNHIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHH
RTQHYVRALARALRDDPRFSAQLDDRTIDLLFKSAPLHDIGKVGIPDRILLKPGKLTAEE
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHCCCCCCHHHCCCCCCCEEEECCCCCCHHH
FEIMKSHTMLGRDAIADAEAQCGTRNSFLRYAREIAHYHHEKWDGTGYPEGLAGDDIPVA
HHHHHHHHHHCHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
ARLMALADVYDALISRRVYKPAFSHEESVRIIMEGRGRHFDPGMVDAFHSIADEFHAIAL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHEEE
RFADPEHEPQRDLLPAI
EECCCCCCCHHHCCCCC
>Mature Secondary Structure 
SADSPEQRPTVLVVDDIPENIAAMVAMLQDQYRVRVATRGAKALQLAASSAPDLILLDV
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHEEEEECCCCHHHHHHHCCCCCEEEEEC
SMPEMDGYETCRHLKANPATAHVPVIFLTARTDELDEARGFEVGAVDYIMKPVSPPVARA
CCCCCCHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHCCCCCCHHHHHHCCCCCHHHHH
RIASQLALKQAHDFLRDRSAYLEAEVQRRTREITQIEDATIIALAALAETRDNETGNHIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHH
RTQHYVRALARALRDDPRFSAQLDDRTIDLLFKSAPLHDIGKVGIPDRILLKPGKLTAEE
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHCCCCCCHHHCCCCCCCEEEECCCCCCHHH
FEIMKSHTMLGRDAIADAEAQCGTRNSFLRYAREIAHYHHEKWDGTGYPEGLAGDDIPVA
HHHHHHHHHHCHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
ARLMALADVYDALISRRVYKPAFSHEESVRIIMEGRGRHFDPGMVDAFHSIADEFHAIAL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHEEE
RFADPEHEPQRDLLPAI
EECCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11123673 [H]