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The map label for this gene is ribB

Identifier: 73537862

GI number: 73537862

Start: 670802

End: 671473

Strand: Direct

Name: ribB

Synonym: Reut_B4029

Alternate gene names: 73537862

Gene position: 670802-671473 (Clockwise)

Preceding gene: 73537860

Following gene: 73537863

Centisome position: 24.61

GC content: 65.18

Gene sequence:

>672_bases
ATGCCAAGCCTTTCCCACGAATCCGATTCCATCACGCTCGCAGCCGATGCCGACGAGCGCCCGTTAGCCCTGCGTATCGC
GCAAGCACTCGATGCCATGCGTGAAGGGCGTCCCGTCGTGCTGCTCGACGATGACGACCGCGAAAACGAAGCCGACCTTA
TCCTGGCCGCGGAATGCCTGACGCCATCCAACATGGCGATGATGATCCGCGAATGCAGCGGCATCGTGTGCCTGTGCCTG
ACGACCGACAAGGTGCGCCAGCTCGGCCTGCGTCCCATGGTGGAAAACAACCGCAGCCAGTATGGAACGGCGTTCACCGT
ATCGATCGAAGCGCGCGAGGGTGTGACCACTGGCGTGAGCGCGGTGGACCGCATCACCACGATCCGTGCGGCGATTGCGA
AGGATGCGGGCACCGATGCTGTCGTCAGCCCCGGGCATGTGTTCCCGCTGGTCGCGGTCGACGGCGGGGTGCTGGTGCGC
CGGGGGCACACCGAAGGTTCGGTCGAACTCGCGCGGATGGCCGGACTGTCGCCGGCCGCGGTGCTTTGCGAGCTGATGAA
TCCCGACGGCACCATGGCGCGCCGTCCGGAAGCGTTGTCGTTTGCCGAGATGTACCGTCTGCCGATCCTGACCATCGCCG
ATCTCGTGGCGTGGCGCGAAATCCACGGCTGA

Upstream 100 bases:

>100_bases
ACGGTGTTGCGCCTTCATGCAATGCGCTCGTGCGGTTGCCTGCGCGCTTTCGTTGATCCTCCCCTGAAACGCCCACTGAT
CAGCTAGCAAGGAGCGTTTC

Downstream 100 bases:

>100_bases
ATTGTGCTGCTCGGGTCGGCAAGTGCGGCTGCCTATGCGACAATGCGGCTCGCTTTTTCCCGTCAATTCGAGGGCGATTC
AATGCTTTTCCGCATATTTC

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MPSLSHESDSITLAADADERPLALRIAQALDAMREGRPVVLLDDDDRENEADLILAAECLTPSNMAMMIRECSGIVCLCL
TTDKVRQLGLRPMVENNRSQYGTAFTVSIEAREGVTTGVSAVDRITTIRAAIAKDAGTDAVVSPGHVFPLVAVDGGVLVR
RGHTEGSVELARMAGLSPAAVLCELMNPDGTMARRPEALSFAEMYRLPILTIADLVAWREIHG

Sequences:

>Translated_223_residues
MPSLSHESDSITLAADADERPLALRIAQALDAMREGRPVVLLDDDDRENEADLILAAECLTPSNMAMMIRECSGIVCLCL
TTDKVRQLGLRPMVENNRSQYGTAFTVSIEAREGVTTGVSAVDRITTIRAAIAKDAGTDAVVSPGHVFPLVAVDGGVLVR
RGHTEGSVELARMAGLSPAAVLCELMNPDGTMARRPEALSFAEMYRLPILTIADLVAWREIHG
>Mature_222_residues
PSLSHESDSITLAADADERPLALRIAQALDAMREGRPVVLLDDDDRENEADLILAAECLTPSNMAMMIRECSGIVCLCLT
TDKVRQLGLRPMVENNRSQYGTAFTVSIEAREGVTTGVSAVDRITTIRAAIAKDAGTDAVVSPGHVFPLVAVDGGVLVRR
GHTEGSVELARMAGLSPAAVLCELMNPDGTMARRPEALSFAEMYRLPILTIADLVAWREIHG

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family

Homologues:

Organism=Escherichia coli, GI1789420, Length=198, Percent_Identity=60.1010101010101, Blast_Score=240, Evalue=6e-65,
Organism=Saccharomyces cerevisiae, GI6320695, Length=202, Percent_Identity=39.6039603960396, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIBB_CUPPJ (Q46TZ9)

Other databases:

- EMBL:   CP000091
- RefSeq:   YP_298229.1
- ProteinModelPortal:   Q46TZ9
- SMR:   Q46TZ9
- GeneID:   3614573
- GenomeReviews:   CP000091_GR
- KEGG:   reu:Reut_B4029
- NMPDR:   fig|264198.3.peg.4496
- HOGENOM:   HBG735778
- OMA:   RGHTEAT
- ProtClustDB:   PRK03353
- BioCyc:   REUT264198:REUT_B4029-MONOMER
- HAMAP:   MF_00180
- InterPro:   IPR017945
- InterPro:   IPR000422
- Gene3D:   G3DSA:3.90.870.10
- TIGRFAMs:   TIGR00506

Pfam domain/function: PF00926 DHBP_synthase; SSF55821 DHBP_synth_RibB-like_a/b_dom

EC number: =4.1.99.12

Molecular weight: Translated: 23925; Mature: 23794

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: BINDING 52-52 BINDING 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLSHESDSITLAADADERPLALRIAQALDAMREGRPVVLLDDDDRENEADLILAAECL
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEECC
TPSNMAMMIRECSGIVCLCLTTDKVRQLGLRPMVENNRSQYGTAFTVSIEAREGVTTGVS
CCCHHHHHHHHCCCEEEEEEEHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHH
AVDRITTIRAAIAKDAGTDAVVSPGHVFPLVAVDGGVLVRRGHTEGSVELARMAGLSPAA
HHHHHHHHHHHHHCCCCCCCEECCCCEEEEEEECCCEEEEECCCCCCEEHHHHCCCCHHH
VLCELMNPDGTMARRPEALSFAEMYRLPILTIADLVAWREIHG
HHHHHCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PSLSHESDSITLAADADERPLALRIAQALDAMREGRPVVLLDDDDRENEADLILAAECL
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEECC
TPSNMAMMIRECSGIVCLCLTTDKVRQLGLRPMVENNRSQYGTAFTVSIEAREGVTTGVS
CCCHHHHHHHHCCCEEEEEEEHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHH
AVDRITTIRAAIAKDAGTDAVVSPGHVFPLVAVDGGVLVRRGHTEGSVELARMAGLSPAA
HHHHHHHHHHHHHCCCCCCCEECCCCEEEEEEECCCEEEEECCCCCCEEHHHHCCCCHHH
VLCELMNPDGTMARRPEALSFAEMYRLPILTIADLVAWREIHG
HHHHHCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA