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The map label for this gene is ydcR [H]

Identifier: 73537773

GI number: 73537773

Start: 571429

End: 572877

Strand: Reverse

Name: ydcR [H]

Synonym: Reut_B3939

Alternate gene names: 73537773

Gene position: 572877-571429 (Counterclockwise)

Preceding gene: 73537774

Following gene: 73537767

Centisome position: 21.01

GC content: 68.74

Gene sequence:

>1449_bases
ATGACAGGCGCCCCCCGGCCGATGACCCGCTATGAAGAACTAGCGGAGGACATTGCCCAGTCCATCCATGCCGGTGTGCT
GCGCCTCGGCGATCGGCTGCCGTCGGTGCGCCAGGCCAGCACCGGCCGCGGCGTCAGCCAGTCGACCGTATTCCAGGCCT
ACTACCTGCTGGAGGCGCGTGGCCTGATCCGCGCGCGCGAGCGTTCCGGCTACTACGTGGCCACGGGCTCGCGCCAGCTT
GCACCGGAGGCGGAAACGCCGTCGGCACCCGTGCAGGAGTCCGGTCCGGTCGATGTCAGCGAACTGGTCTTCAAGGTGCT
GGAGTCCACGATGCGGCGCGACGTGGTGCCATTCGGCTCGGCATTCCCGAGCCCCTTGCTGTTCCCGATGCAGCGGCTGG
CCAAGACCATGGCCACGACCGTGCAGAAGCTGGACCCATGGAGCAGTGTCGACGACCTCACGCCAGGCAATGCGAACCTG
CGCCGCCAGATCGCGCTGCGCTACCTGGCGGACGGGCTGACCGTGCAGGCCGACGAGATCGTCGTCACCAACGGCGCGCT
GGAGGCGCTGAACCTGTGCCTGATGGCCGTCACGCGTCCCGGCGATGCGGTGGTGATCGAAAGCCCGACGTTCTACGCGG
CGCTGCAGGCACTGGAACGCTGTGGCCTGTCTGCCATCGAGGTGCCCACGCATCCGCGCGAGGGCATCGAGCTGGGCGCG
CTGGAGCAGGCACTGGAGCGGCACCGCCCGAAGGCGTGCTGGCTGATGACCAACTTCCAGAACCCGCTTGGCTCGCTGAT
GCCCGACGCGAAGAAGCAGGCGCTCGTCGAACTGCTGGCGCGGTATGAGGTACCGCTGATCGAAGACGATGTCTATGGCG
AGCTCTACTTCGGCACGCGCCGCCCCACGCCGGCCAAGGCGTTCGACAAGGCCGGGCTGGTCATGCACTGCGCATCGTTC
TCGAAGTGTCTGGCGCCGGGCTATCGCGTTGGCTGGGCCGCACCCGGCCGCTTCGCGCGCGATGTCGCGCGGCTCAAGCT
GACCACGACGCTGGCCGGCTCCGCGCCCGCGCAGGTGGCCATTGCGGCGTACCTGGAAAAAGGCGGTTATGACCGGCACC
TGCGCCAGCTCAGGCACGCGCTCATGCTGCGGCAGGATGCCGTGGCACAGGCGGTGGCGCGGCACTTCCCGCCCGGCACG
CGTGCGACGCGCCCGGCGGGCGGCTATTTCCTGTGGATCGAACTGCCTGAAGACACCGACACGCTGGCGCTGCAACAGCT
GGCGCTGTCGCACGGCATCAGCATCGCACCGGGGCCGATCTTCTCGGCCCGGCACAGTTTCCGCAATTGCCTGCGGCTCA
ACTACGGACACGAATGGGACAAGCGTGCCGAGACCGCGCTGGCCACGCTGGGCCGGCTGGCCGGCGCGGTGGCCGGCACA
CGGTCGTAA

Upstream 100 bases:

>100_bases
CGGGCCTGCTCCCTTCATGTAGTGGGAATCCAGATACCTGCCTGGTCCTGATCTTCCCAATCCATTACAGTTGACAAAAC
TGCCAAAAGGACAAGATCAG

Downstream 100 bases:

>100_bases
CGGAAATCAACCCTCAGCGCGCGAGGCTGCGTAGACCTTCGGCGCAACCTGTTCTGACGGCACCGCGCCCACCGATGCGG
CGCGCCGATGGTCGATGCCG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MTGAPRPMTRYEELAEDIAQSIHAGVLRLGDRLPSVRQASTGRGVSQSTVFQAYYLLEARGLIRARERSGYYVATGSRQL
APEAETPSAPVQESGPVDVSELVFKVLESTMRRDVVPFGSAFPSPLLFPMQRLAKTMATTVQKLDPWSSVDDLTPGNANL
RRQIALRYLADGLTVQADEIVVTNGALEALNLCLMAVTRPGDAVVIESPTFYAALQALERCGLSAIEVPTHPREGIELGA
LEQALERHRPKACWLMTNFQNPLGSLMPDAKKQALVELLARYEVPLIEDDVYGELYFGTRRPTPAKAFDKAGLVMHCASF
SKCLAPGYRVGWAAPGRFARDVARLKLTTTLAGSAPAQVAIAAYLEKGGYDRHLRQLRHALMLRQDAVAQAVARHFPPGT
RATRPAGGYFLWIELPEDTDTLALQQLALSHGISIAPGPIFSARHSFRNCLRLNYGHEWDKRAETALATLGRLAGAVAGT
RS

Sequences:

>Translated_482_residues
MTGAPRPMTRYEELAEDIAQSIHAGVLRLGDRLPSVRQASTGRGVSQSTVFQAYYLLEARGLIRARERSGYYVATGSRQL
APEAETPSAPVQESGPVDVSELVFKVLESTMRRDVVPFGSAFPSPLLFPMQRLAKTMATTVQKLDPWSSVDDLTPGNANL
RRQIALRYLADGLTVQADEIVVTNGALEALNLCLMAVTRPGDAVVIESPTFYAALQALERCGLSAIEVPTHPREGIELGA
LEQALERHRPKACWLMTNFQNPLGSLMPDAKKQALVELLARYEVPLIEDDVYGELYFGTRRPTPAKAFDKAGLVMHCASF
SKCLAPGYRVGWAAPGRFARDVARLKLTTTLAGSAPAQVAIAAYLEKGGYDRHLRQLRHALMLRQDAVAQAVARHFPPGT
RATRPAGGYFLWIELPEDTDTLALQQLALSHGISIAPGPIFSARHSFRNCLRLNYGHEWDKRAETALATLGRLAGAVAGT
RS
>Mature_481_residues
TGAPRPMTRYEELAEDIAQSIHAGVLRLGDRLPSVRQASTGRGVSQSTVFQAYYLLEARGLIRARERSGYYVATGSRQLA
PEAETPSAPVQESGPVDVSELVFKVLESTMRRDVVPFGSAFPSPLLFPMQRLAKTMATTVQKLDPWSSVDDLTPGNANLR
RQIALRYLADGLTVQADEIVVTNGALEALNLCLMAVTRPGDAVVIESPTFYAALQALERCGLSAIEVPTHPREGIELGAL
EQALERHRPKACWLMTNFQNPLGSLMPDAKKQALVELLARYEVPLIEDDVYGELYFGTRRPTPAKAFDKAGLVMHCASFS
KCLAPGYRVGWAAPGRFARDVARLKLTTTLAGSAPAQVAIAAYLEKGGYDRHLRQLRHALMLRQDAVAQAVARHFPPGTR
ATRPAGGYFLWIELPEDTDTLALQQLALSHGISIAPGPIFSARHSFRNCLRLNYGHEWDKRAETALATLGRLAGAVAGTR
S

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=312, Percent_Identity=25.9615384615385, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI33469970, Length=312, Percent_Identity=25.9615384615385, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4507369, Length=308, Percent_Identity=24.6753246753247, Blast_Score=86, Evalue=9e-17,
Organism=Escherichia coli, GI1787710, Length=466, Percent_Identity=48.9270386266094, Blast_Score=442, Evalue=1e-125,
Organism=Escherichia coli, GI1790797, Length=470, Percent_Identity=39.3617021276596, Blast_Score=318, Evalue=3e-88,
Organism=Saccharomyces cerevisiae, GI6321236, Length=319, Percent_Identity=24.7648902821317, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321000, Length=418, Percent_Identity=23.9234449760766, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322401, Length=271, Percent_Identity=25.830258302583, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6321929, Length=364, Percent_Identity=21.4285714285714, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356535, Length=320, Percent_Identity=25, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52596; Mature: 52465

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGAPRPMTRYEELAEDIAQSIHAGVLRLGDRLPSVRQASTGRGVSQSTVFQAYYLLEAR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHH
GLIRARERSGYYVATGSRQLAPEAETPSAPVQESGPVDVSELVFKVLESTMRRDVVPFGS
HHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
AFPSPLLFPMQRLAKTMATTVQKLDPWSSVDDLTPGNANLRRQIALRYLADGLTVQADEI
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCE
VVTNGALEALNLCLMAVTRPGDAVVIESPTFYAALQALERCGLSAIEVPTHPREGIELGA
EEECCHHHHHHHHHHHEECCCCEEEEECCHHHHHHHHHHHCCCCEEECCCCCCCCCHHHH
LEQALERHRPKACWLMTNFQNPLGSLMPDAKKQALVELLARYEVPLIEDDVYGELYFGTR
HHHHHHHCCCCEEEEEECCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCC
RPTPAKAFDKAGLVMHCASFSKCLAPGYRVGWAAPGRFARDVARLKLTTTLAGSAPAQVA
CCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHH
IAAYLEKGGYDRHLRQLRHALMLRQDAVAQAVARHFPPGTRATRPAGGYFLWIELPEDTD
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCH
TLALQQLALSHGISIAPGPIFSARHSFRNCLRLNYGHEWDKRAETALATLGRLAGAVAGT
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
RS
CC
>Mature Secondary Structure 
TGAPRPMTRYEELAEDIAQSIHAGVLRLGDRLPSVRQASTGRGVSQSTVFQAYYLLEAR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHH
GLIRARERSGYYVATGSRQLAPEAETPSAPVQESGPVDVSELVFKVLESTMRRDVVPFGS
HHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
AFPSPLLFPMQRLAKTMATTVQKLDPWSSVDDLTPGNANLRRQIALRYLADGLTVQADEI
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCE
VVTNGALEALNLCLMAVTRPGDAVVIESPTFYAALQALERCGLSAIEVPTHPREGIELGA
EEECCHHHHHHHHHHHEECCCCEEEEECCHHHHHHHHHHHCCCCEEECCCCCCCCCHHHH
LEQALERHRPKACWLMTNFQNPLGSLMPDAKKQALVELLARYEVPLIEDDVYGELYFGTR
HHHHHHHCCCCEEEEEECCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCC
RPTPAKAFDKAGLVMHCASFSKCLAPGYRVGWAAPGRFARDVARLKLTTTLAGSAPAQVA
CCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHH
IAAYLEKGGYDRHLRQLRHALMLRQDAVAQAVARHFPPGTRATRPAGGYFLWIELPEDTD
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCH
TLALQQLALSHGISIAPGPIFSARHSFRNCLRLNYGHEWDKRAETALATLGRLAGAVAGT
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
RS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]