Click here to switch to the map view.

The map label for this gene is 73537720

Identifier: 73537720

GI number: 73537720

Start: 508027

End: 509172

Strand: Reverse

Name: 73537720

Synonym: Reut_B3886

Alternate gene names: NA

Gene position: 509172-508027 (Counterclockwise)

Preceding gene: 73537721

Following gene: 73537719

Centisome position: 18.68

GC content: 70.77

Gene sequence:

>1146_bases
ATGGCCGGCACAAGCTACATACGCGGCACCGGCAACACGCGCTTCGGCCGCCTGGAGGGCAGCACGCCGCTGACGCTGAT
GGCGCAGGCCGCCGATGCCGCACTGGCCGACAGCGGACTGGCGCGCGCGGACATCGACGGCGCGCTGTGCGGCTACGCCA
CCACGCTGCCGCACCTGATGCTGGCCGACCGCTTCTGCGAGTACGCGTCGCTCACGCCGGCCTATGCGCACGGTGTTGCC
GCGGGCGGCGCTACCGGCGGCGTGATGGCAATGCTCGCGCACGAACTGGTGCGCGCCGGCCGCTGCCGCCATGTGCTGGT
CGTGGCCGGCGAAAACCGCCTTAGCGGCCAGAGCCGCGACCAATCGATCCAGACGCTGGCGCAGGTGGGCGAACCGCATG
CCGAGGTGCCGAACGGCGCTTCGGTGCCGGCCTACTATGCGCTGCTGGCCTCGCGCTACCTGCATGAAGCCGGCATGGAC
GCCGATGCGCTGTCGGGCTTTGCCGTGCTGATGCGCGAGCACGCGGCGAGCCATCCCGATGCACATTTGCGCGAGCCGCT
GTCATTGGCTGATGCGCGTGCCGCACGGGCCATCGCGACGCCGCTGCGGCTGTCGGATTGCTGCCCGATCTCCGATGGCG
CAGTTGCCGTGGTCGTGTCCGCCGAGCCTGGCGTCGGCACGCCGGTGCGCATCGCGGGCGCAGGACAGGCGCATCGGCAC
CAGCATCTGAGCGCGATCGACGACGTCATGCAGACCGGCGCCGCCGACGCCGCGCGGCGCGCGTTTGCCGAAGCTGGCGG
CGGCGTGGAAAGCATCGATTACCTGGCCATCTACGACTCGTTCACGATCACGCTGGTCATGCTGCTGGAAGAACTCGGAC
TCGCTGAACGCGGTCGGGCGCAGGCACGGCTGCGCGCGGGCGATTTCGGACGTAACGGCCCGTTGGCACTCAATACGCAT
GGCGGCTTGCTCGCCTTCGGGCATTCGGGCGTGGCCGGCGGCCTGATGCACCTGGCCGAAGCCGCGCGCCAGCTCGGCGG
CCGCGCCGGTGAACGCCAGGCCGGCACGCGCCTGCGCGCGCTGTTCCATGCCGACGGCGGCGTGCTGTCATCCCACGTCA
GCCTGGTGCTGGAGGCCATGCCATGA

Upstream 100 bases:

>100_bases
AAGTATCCGTGGGACTACTACAAGGTGCTCGCGACGGTGCCGGGCGACCAGGCTTTCATGCCCGCGTCGAAGTCGCAATG
CCCGCTGCTCAAGCGCTGAC

Downstream 100 bases:

>100_bases
CCCATCCCTATACCGACGGCCTGGACGTCGGCGTGGTGCGCTACCAGTGCTGCGACGACTGCGGCGCCTGGCAGCCGATG
GAGCGCCATGCCTGCCGTCG

Product: thiolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MAGTSYIRGTGNTRFGRLEGSTPLTLMAQAADAALADSGLARADIDGALCGYATTLPHLMLADRFCEYASLTPAYAHGVA
AGGATGGVMAMLAHELVRAGRCRHVLVVAGENRLSGQSRDQSIQTLAQVGEPHAEVPNGASVPAYYALLASRYLHEAGMD
ADALSGFAVLMREHAASHPDAHLREPLSLADARAARAIATPLRLSDCCPISDGAVAVVVSAEPGVGTPVRIAGAGQAHRH
QHLSAIDDVMQTGAADAARRAFAEAGGGVESIDYLAIYDSFTITLVMLLEELGLAERGRAQARLRAGDFGRNGPLALNTH
GGLLAFGHSGVAGGLMHLAEAARQLGGRAGERQAGTRLRALFHADGGVLSSHVSLVLEAMP

Sequences:

>Translated_381_residues
MAGTSYIRGTGNTRFGRLEGSTPLTLMAQAADAALADSGLARADIDGALCGYATTLPHLMLADRFCEYASLTPAYAHGVA
AGGATGGVMAMLAHELVRAGRCRHVLVVAGENRLSGQSRDQSIQTLAQVGEPHAEVPNGASVPAYYALLASRYLHEAGMD
ADALSGFAVLMREHAASHPDAHLREPLSLADARAARAIATPLRLSDCCPISDGAVAVVVSAEPGVGTPVRIAGAGQAHRH
QHLSAIDDVMQTGAADAARRAFAEAGGGVESIDYLAIYDSFTITLVMLLEELGLAERGRAQARLRAGDFGRNGPLALNTH
GGLLAFGHSGVAGGLMHLAEAARQLGGRAGERQAGTRLRALFHADGGVLSSHVSLVLEAMP
>Mature_380_residues
AGTSYIRGTGNTRFGRLEGSTPLTLMAQAADAALADSGLARADIDGALCGYATTLPHLMLADRFCEYASLTPAYAHGVAA
GGATGGVMAMLAHELVRAGRCRHVLVVAGENRLSGQSRDQSIQTLAQVGEPHAEVPNGASVPAYYALLASRYLHEAGMDA
DALSGFAVLMREHAASHPDAHLREPLSLADARAARAIATPLRLSDCCPISDGAVAVVVSAEPGVGTPVRIAGAGQAHRHQ
HLSAIDDVMQTGAADAARRAFAEAGGGVESIDYLAIYDSFTITLVMLLEELGLAERGRAQARLRAGDFGRNGPLALNTHG
GLLAFGHSGVAGGLMHLAEAARQLGGRAGERQAGTRLRALFHADGGVLSSHVSLVLEAMP

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=388, Percent_Identity=25.5154639175258, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI302344760, Length=306, Percent_Identity=25.1633986928105, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI302344767, Length=306, Percent_Identity=25.1633986928105, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI302344762, Length=231, Percent_Identity=25.974025974026, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537653, Length=387, Percent_Identity=22.7390180878553, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19921506, Length=381, Percent_Identity=24.6719160104987, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24585051, Length=379, Percent_Identity=25.065963060686, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 39300; Mature: 39169

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGTSYIRGTGNTRFGRLEGSTPLTLMAQAADAALADSGLARADIDGALCGYATTLPHLM
CCCCCEEECCCCCEEEEECCCCCCEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
LADRFCEYASLTPAYAHGVAAGGATGGVMAMLAHELVRAGRCRHVLVVAGENRLSGQSRD
HHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHH
QSIQTLAQVGEPHAEVPNGASVPAYYALLASRYLHEAGMDADALSGFAVLMREHAASHPD
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
AHLREPLSLADARAARAIATPLRLSDCCPISDGAVAVVVSAEPGVGTPVRIAGAGQAHRH
HHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEECCCCHHHH
QHLSAIDDVMQTGAADAARRAFAEAGGGVESIDYLAIYDSFTITLVMLLEELGLAERGRA
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCH
QARLRAGDFGRNGPLALNTHGGLLAFGHSGVAGGLMHLAEAARQLGGRAGERQAGTRLRA
HHHEECCCCCCCCCEEEECCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LFHADGGVLSSHVSLVLEAMP
HHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGTSYIRGTGNTRFGRLEGSTPLTLMAQAADAALADSGLARADIDGALCGYATTLPHLM
CCCCEEECCCCCEEEEECCCCCCEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
LADRFCEYASLTPAYAHGVAAGGATGGVMAMLAHELVRAGRCRHVLVVAGENRLSGQSRD
HHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHH
QSIQTLAQVGEPHAEVPNGASVPAYYALLASRYLHEAGMDADALSGFAVLMREHAASHPD
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
AHLREPLSLADARAARAIATPLRLSDCCPISDGAVAVVVSAEPGVGTPVRIAGAGQAHRH
HHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEECCCCHHHH
QHLSAIDDVMQTGAADAARRAFAEAGGGVESIDYLAIYDSFTITLVMLLEELGLAERGRA
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCH
QARLRAGDFGRNGPLALNTHGGLLAFGHSGVAGGLMHLAEAARQLGGRAGERQAGTRLRA
HHHEECCCCCCCCCEEEECCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LFHADGGVLSSHVSLVLEAMP
HHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]