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The map label for this gene is virS [H]

Identifier: 73537681

GI number: 73537681

Start: 461762

End: 462778

Strand: Reverse

Name: virS [H]

Synonym: Reut_B3846

Alternate gene names: 73537681

Gene position: 462778-461762 (Counterclockwise)

Preceding gene: 73537685

Following gene: 73537678

Centisome position: 16.98

GC content: 64.6

Gene sequence:

>1017_bases
ATGTCGACGCTGCTGCAACACGTGAACCTGACGGAGTTTGTTGACGTGGCCCGCCAACTCGGCCTGGACCCTTACCGTCA
ACTGCGGCAAGCAGGTATCCGGCCGACGGCGCTGGTCGACCCGGAAATGCGCGTGCCTGCGAAGTCGGTCATGCAGTTGC
TGGAGGATTCGGCACAGCTTGCGGGCCTGGAGGACCTCGGGCTACGCGTCGCGGAAGCGCGTGAACTGACCACTCTGGGC
CCGCTGTGGACGGTGATGCGCGAGGGCGCCACCCTGCGCAACGCGCTGGGGGCGATGGCGCGCTACCTGCATTTGCTCAA
CGAAGCACTCGATCTGCGCCTCGAGGAAGTCGGGGACACCGCGGTGGTCAGGCTTGAATTCCTGGTGTCCGTGGACGGTT
CCATGCGGCAATCGACCGAGTTCATCATCTGCCTGTGGTTCCGGCTGTTCAAGCTGCTGTCGGGCGATGCATGGAAGCCG
CGCAGCGTCTGCTTCACCCACGCCGCGCCGGCGAGCCTTGCCACGCATCGGCGCGTGTTCGGCGTACCGGTGCGATTCCA
CCAGGATTTCGATGGCATCCTGCTGTCCGCCGCGGATCTCGACGTGGCGGGCACGACGTCGGACACGGCGCTGGGCCGCC
ATGCGCGCGAATTTCTCGATACCAAGCTGGCACAGTCCGATTCCACCATGCCGGACAAGGTACGGAAACTGGTATTCGCG
CTGCTGCCCACCGGCGAGTGCGGGGCCGAACAGGTGGCCCGGCAGCTTGGCATCGACCGCAAGACCATGCATCGCCATCT
GGCAGCCTATGGACAGAACTACCTGTCCGTCGTCGATGCGGTCAGGGTCGAGCTCGTCACGAGATACCTGAAGAACAACG
AACGACCGTTGTCGGACGTGGCGATCCTGATGGGGTTTTCCTCGCTCAGCGCCTTCTCCAGGTGGTTTGCCACGCGCTAC
GGCTGCAGCGTGTCGGCATGGCGCCGCCAGCGGACAGCACCGGAAATCAGGCGCTAG

Upstream 100 bases:

>100_bases
CGAAGCAAAAGGGTCGATGCAAGTATTGAAGAGGCGGCGCGCGATGCGTTGACATTCCGGGGCAGTGACTTTACATTTTG
GGGCACCTGGGGGAACTCCT

Downstream 100 bases:

>100_bases
GCGCCGCGCATCGCGCCTGGCCTGCTGACACAGTCCGGCCCCAGATCCGTGAGCGCCGGGCAGCCGAGCAGGCCCAGCGT
GCGATCGATCTCGGCACGCA

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSTLLQHVNLTEFVDVARQLGLDPYRQLRQAGIRPTALVDPEMRVPAKSVMQLLEDSAQLAGLEDLGLRVAEARELTTLG
PLWTVMREGATLRNALGAMARYLHLLNEALDLRLEEVGDTAVVRLEFLVSVDGSMRQSTEFIICLWFRLFKLLSGDAWKP
RSVCFTHAAPASLATHRRVFGVPVRFHQDFDGILLSAADLDVAGTTSDTALGRHAREFLDTKLAQSDSTMPDKVRKLVFA
LLPTGECGAEQVARQLGIDRKTMHRHLAAYGQNYLSVVDAVRVELVTRYLKNNERPLSDVAILMGFSSLSAFSRWFATRY
GCSVSAWRRQRTAPEIRR

Sequences:

>Translated_338_residues
MSTLLQHVNLTEFVDVARQLGLDPYRQLRQAGIRPTALVDPEMRVPAKSVMQLLEDSAQLAGLEDLGLRVAEARELTTLG
PLWTVMREGATLRNALGAMARYLHLLNEALDLRLEEVGDTAVVRLEFLVSVDGSMRQSTEFIICLWFRLFKLLSGDAWKP
RSVCFTHAAPASLATHRRVFGVPVRFHQDFDGILLSAADLDVAGTTSDTALGRHAREFLDTKLAQSDSTMPDKVRKLVFA
LLPTGECGAEQVARQLGIDRKTMHRHLAAYGQNYLSVVDAVRVELVTRYLKNNERPLSDVAILMGFSSLSAFSRWFATRY
GCSVSAWRRQRTAPEIRR
>Mature_337_residues
STLLQHVNLTEFVDVARQLGLDPYRQLRQAGIRPTALVDPEMRVPAKSVMQLLEDSAQLAGLEDLGLRVAEARELTTLGP
LWTVMREGATLRNALGAMARYLHLLNEALDLRLEEVGDTAVVRLEFLVSVDGSMRQSTEFIICLWFRLFKLLSGDAWKPR
SVCFTHAAPASLATHRRVFGVPVRFHQDFDGILLSAADLDVAGTTSDTALGRHAREFLDTKLAQSDSTMPDKVRKLVFAL
LPTGECGAEQVARQLGIDRKTMHRHLAAYGQNYLSVVDAVRVELVTRYLKNNERPLSDVAILMGFSSLSAFSRWFATRYG
CSVSAWRRQRTAPEIRR

Specific function: May have a role in the regulation of proteins necessary for virulence [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 37808; Mature: 37677

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLLQHVNLTEFVDVARQLGLDPYRQLRQAGIRPTALVDPEMRVPAKSVMQLLEDSAQL
CCHHHHHCCHHHHHHHHHHHCCCHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHH
AGLEDLGLRVAEARELTTLGPLWTVMREGATLRNALGAMARYLHLLNEALDLRLEEVGDT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AVVRLEFLVSVDGSMRQSTEFIICLWFRLFKLLSGDAWKPRSVCFTHAAPASLATHRRVF
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEECCCCHHHHHHHHHH
GVPVRFHQDFDGILLSAADLDVAGTTSDTALGRHAREFLDTKLAQSDSTMPDKVRKLVFA
CCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LLPTGECGAEQVARQLGIDRKTMHRHLAAYGQNYLSVVDAVRVELVTRYLKNNERPLSDV
HCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AILMGFSSLSAFSRWFATRYGCSVSAWRRQRTAPEIRR
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
STLLQHVNLTEFVDVARQLGLDPYRQLRQAGIRPTALVDPEMRVPAKSVMQLLEDSAQL
CHHHHHCCHHHHHHHHHHHCCCHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHH
AGLEDLGLRVAEARELTTLGPLWTVMREGATLRNALGAMARYLHLLNEALDLRLEEVGDT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AVVRLEFLVSVDGSMRQSTEFIICLWFRLFKLLSGDAWKPRSVCFTHAAPASLATHRRVF
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEECCCCHHHHHHHHHH
GVPVRFHQDFDGILLSAADLDVAGTTSDTALGRHAREFLDTKLAQSDSTMPDKVRKLVFA
CCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LLPTGECGAEQVARQLGIDRKTMHRHLAAYGQNYLSVVDAVRVELVTRYLKNNERPLSDV
HCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AILMGFSSLSAFSRWFATRYGCSVSAWRRQRTAPEIRR
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472958; 9634230; 12218036 [H]