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The map label for this gene is tcp [H]

Identifier: 73537643

GI number: 73537643

Start: 415156

End: 416865

Strand: Direct

Name: tcp [H]

Synonym: Reut_B3808

Alternate gene names: 73537643

Gene position: 415156-416865 (Clockwise)

Preceding gene: 73537639

Following gene: 73537644

Centisome position: 15.23

GC content: 66.02

Gene sequence:

>1710_bases
ATGAGTCAGTTCATCCATACGATCAAGTTCAGGATCCTCCTGGTGTTCAGTGTTTGTATCGCGCTGATGCTGGCGATCGG
GCTTTTCGCCTTGCAAACCATCTCGAGCCTGAACGAGAACATGCACGACGCCTACGAGCAGAACACCGTGGCCATCGGCG
AGCTGGCGGACGTCCGCGTGGCACAGCTCCATATCCGCCGGCTGCTGTGGAAAATCCAGGCGACTTCGGAGGACGAAGGC
AGTGCGGACATGGCCCTGGTGCGCGAATACCAGGCAAAAATGAAGAAGGGCTGGCAAGCCTATTACCCCACGCGGGTCAC
GTCGCCGCGCGAGCGGGACATGGCGGATCAGCTTGACACGGCGCTGGCGCGCTTCGCGGATCTTGTCGCACAGGAGCTGC
ACCTGCTCGAAGCCGGTGACCGGGCCGCGGCAGCCCGTCTGCAGGAAAGCGATCTCGGTGCGGCCGGCGACAAGGTCGGC
GAGCTCATCACGCGCGGTGTGGAAGTCAACCTGAACCAGGCCGGTGACTACCATCGCCGGAGTCTCACGGAGGCGCGTTC
AGCGCTGTGGACGACCGCGGTGCTGGTGGTGCTTGGGTTGCTCGTTTCGCTGGGGGCGTCGCACTATCTGCTGCGAACCA
TTACGCGCCAGCTTCGCCGCTCCGTGGAAATCGCCGACGAGATCGCCGGAGGCCGCCTGGACCAGCAGATCGAGATTCGC
TCGCGCGACGAGTTCGGCCTGCTGTTTGGTGCCATGGCGCGCATGAGCAGCCAGCTTGCGCAAACGGTCCGCGGCATCCA
GGTATCGAGCGAGGCCGTGCGTGTGGCATCGCGTGAAATCGCCAGCGGCAATATGGATTTGTCCGCGCGCACGGAGCAAC
AGGCGGCCTCGCTCCAGGAGACCGCGGCCAGCATGACGGAGATCTCCCAGACCGTGCGCATGAACGCTGACAACGCGTCC
CAGGCCAACACGCTGGCCGGCAGTGCGCGAGACCTTGCGCATGCCGGCAACGCGGCGGTGCAGGCCATGGTGCAGACGAT
GGCCCGGATCAGCGGCAGTTCGGGGCGGATCTCGGACATCACCAGCCTGATCGAGGGCATTGCCTTCCAGACCAATATCC
TGGCGCTGAACGCGGCGGTGGAGGCCGCACGTGCCGGCGAGCAGGGGCGCGGATTCGCGGTCGTGGCGGGCGAGGTGCGG
GCGCTGGCGCAGCGCTCTTCGGCGGCCGCCAAGGAAATCAAGGAGCTGATCGAGTCCTCCGCGGACATGGTCCAGGACGG
TTCGCGGCAAGCGGGGGAGGTCGGCCAGACCATGGGTGAGGTGATCCGTGCGATCCAGCAGGTGTCGGACATCATGGGCG
AGATCTCCGTGGCGTCCGGCGAGCAGAGCCAGGGCGTGGAACAGGTGCACCTCGCGATCAGCCAGATCGATTCAGGCACC
CAGCAGAATGCCGCGCTGGTCGAACAGTCCGCCGCGGCGGCGAAGTCGCTGGAAGAGCAGGCCAATGCCATGGCCGATGC
GGTTTCGGTATTCCGGATCGCGGGGGAGGGAGGGAGCCGTGTGCAGGGCGCGCCATCGGTGTCCGTCGCACGCGGATTCA
GCGGCACGCAACCGGGCTTGCAGGCCGTGCGCAGGCCGCCCCCGGCCGCTCAGCCTGCACGGGCCCCGCGTGTTGGCGAT
GAGGCCGACAACGATTGGCATTCCTTCTGA

Upstream 100 bases:

>100_bases
AAACCGCGCCTGGCCATTGTGCCGACGCAGACCGCGTCCGCACAGGCATGCCGGCCGCGAGTATCGGGGGTTTCACCCAG
CCTGCAATCGAATTTCCACA

Downstream 100 bases:

>100_bases
GCCGTGTCCCGGCATAGCCATCGCATGCCGTCACAAAGGCGTGAATATGGCAAGCCGGCCGCAACTATTCGGGGCTTTGC
TCCGAGGCCCAATCCTTAGA

Product: histidine kinase

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MSQFIHTIKFRILLVFSVCIALMLAIGLFALQTISSLNENMHDAYEQNTVAIGELADVRVAQLHIRRLLWKIQATSEDEG
SADMALVREYQAKMKKGWQAYYPTRVTSPRERDMADQLDTALARFADLVAQELHLLEAGDRAAAARLQESDLGAAGDKVG
ELITRGVEVNLNQAGDYHRRSLTEARSALWTTAVLVVLGLLVSLGASHYLLRTITRQLRRSVEIADEIAGGRLDQQIEIR
SRDEFGLLFGAMARMSSQLAQTVRGIQVSSEAVRVASREIASGNMDLSARTEQQAASLQETAASMTEISQTVRMNADNAS
QANTLAGSARDLAHAGNAAVQAMVQTMARISGSSGRISDITSLIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVR
ALAQRSSAAAKEIKELIESSADMVQDGSRQAGEVGQTMGEVIRAIQQVSDIMGEISVASGEQSQGVEQVHLAISQIDSGT
QQNAALVEQSAAAAKSLEEQANAMADAVSVFRIAGEGGSRVQGAPSVSVARGFSGTQPGLQAVRRPPPAAQPARAPRVGD
EADNDWHSF

Sequences:

>Translated_569_residues
MSQFIHTIKFRILLVFSVCIALMLAIGLFALQTISSLNENMHDAYEQNTVAIGELADVRVAQLHIRRLLWKIQATSEDEG
SADMALVREYQAKMKKGWQAYYPTRVTSPRERDMADQLDTALARFADLVAQELHLLEAGDRAAAARLQESDLGAAGDKVG
ELITRGVEVNLNQAGDYHRRSLTEARSALWTTAVLVVLGLLVSLGASHYLLRTITRQLRRSVEIADEIAGGRLDQQIEIR
SRDEFGLLFGAMARMSSQLAQTVRGIQVSSEAVRVASREIASGNMDLSARTEQQAASLQETAASMTEISQTVRMNADNAS
QANTLAGSARDLAHAGNAAVQAMVQTMARISGSSGRISDITSLIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVR
ALAQRSSAAAKEIKELIESSADMVQDGSRQAGEVGQTMGEVIRAIQQVSDIMGEISVASGEQSQGVEQVHLAISQIDSGT
QQNAALVEQSAAAAKSLEEQANAMADAVSVFRIAGEGGSRVQGAPSVSVARGFSGTQPGLQAVRRPPPAAQPARAPRVGD
EADNDWHSF
>Mature_568_residues
SQFIHTIKFRILLVFSVCIALMLAIGLFALQTISSLNENMHDAYEQNTVAIGELADVRVAQLHIRRLLWKIQATSEDEGS
ADMALVREYQAKMKKGWQAYYPTRVTSPRERDMADQLDTALARFADLVAQELHLLEAGDRAAAARLQESDLGAAGDKVGE
LITRGVEVNLNQAGDYHRRSLTEARSALWTTAVLVVLGLLVSLGASHYLLRTITRQLRRSVEIADEIAGGRLDQQIEIRS
RDEFGLLFGAMARMSSQLAQTVRGIQVSSEAVRVASREIASGNMDLSARTEQQAASLQETAASMTEISQTVRMNADNASQ
ANTLAGSARDLAHAGNAAVQAMVQTMARISGSSGRISDITSLIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRA
LAQRSSAAAKEIKELIESSADMVQDGSRQAGEVGQTMGEVIRAIQQVSDIMGEISVASGEQSQGVEQVHLAISQIDSGTQ
QNAALVEQSAAAAKSLEEQANAMADAVSVFRIAGEGGSRVQGAPSVSVARGFSGTQPGLQAVRRPPPAAQPARAPRVGDE
ADNDWHSF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=344, Percent_Identity=51.1627906976744, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1788194, Length=347, Percent_Identity=48.4149855907781, Blast_Score=271, Evalue=8e-74,
Organism=Escherichia coli, GI2367378, Length=326, Percent_Identity=52.4539877300613, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1787690, Length=421, Percent_Identity=40.3800475059382, Blast_Score=264, Evalue=1e-71,
Organism=Escherichia coli, GI1789453, Length=327, Percent_Identity=38.8379204892966, Blast_Score=206, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 60714; Mature: 60583

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFIHTIKFRILLVFSVCIALMLAIGLFALQTISSLNENMHDAYEQNTVAIGELADVRV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHH
AQLHIRRLLWKIQATSEDEGSADMALVREYQAKMKKGWQAYYPTRVTSPRERDMADQLDT
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHH
ALARFADLVAQELHLLEAGDRAAAARLQESDLGAAGDKVGELITRGVEVNLNQAGDYHRR
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCEEECCCCCCHHHH
SLTEARSALWTTAVLVVLGLLVSLGASHYLLRTITRQLRRSVEIADEIAGGRLDQQIEIR
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
SRDEFGLLFGAMARMSSQLAQTVRGIQVSSEAVRVASREIASGNMDLSARTEQQAASLQE
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
TAASMTEISQTVRMNADNASQANTLAGSARDLAHAGNAAVQAMVQTMARISGSSGRISDI
HHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHH
TSLIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRALAQRSSAAAKEIKELIESS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
ADMVQDGSRQAGEVGQTMGEVIRAIQQVSDIMGEISVASGEQSQGVEQVHLAISQIDSGT
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHCCCC
QQNAALVEQSAAAAKSLEEQANAMADAVSVFRIAGEGGSRVQGAPSVSVARGFSGTQPGL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCHHH
QAVRRPPPAAQPARAPRVGDEADNDWHSF
HHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SQFIHTIKFRILLVFSVCIALMLAIGLFALQTISSLNENMHDAYEQNTVAIGELADVRV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHH
AQLHIRRLLWKIQATSEDEGSADMALVREYQAKMKKGWQAYYPTRVTSPRERDMADQLDT
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHH
ALARFADLVAQELHLLEAGDRAAAARLQESDLGAAGDKVGELITRGVEVNLNQAGDYHRR
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCEEECCCCCCHHHH
SLTEARSALWTTAVLVVLGLLVSLGASHYLLRTITRQLRRSVEIADEIAGGRLDQQIEIR
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
SRDEFGLLFGAMARMSSQLAQTVRGIQVSSEAVRVASREIASGNMDLSARTEQQAASLQE
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
TAASMTEISQTVRMNADNASQANTLAGSARDLAHAGNAAVQAMVQTMARISGSSGRISDI
HHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHH
TSLIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRALAQRSSAAAKEIKELIESS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
ADMVQDGSRQAGEVGQTMGEVIRAIQQVSDIMGEISVASGEQSQGVEQVHLAISQIDSGT
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHCCCC
QQNAALVEQSAAAAKSLEEQANAMADAVSVFRIAGEGGSRVQGAPSVSVARGFSGTQPGL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCHHH
QAVRRPPPAAQPARAPRVGDEADNDWHSF
HHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]