Click here to switch to the map view.

The map label for this gene is 73537620

Identifier: 73537620

GI number: 73537620

Start: 387060

End: 388022

Strand: Direct

Name: 73537620

Synonym: Reut_B3785

Alternate gene names: NA

Gene position: 387060-388022 (Clockwise)

Preceding gene: 73537609

Following gene: 73537621

Centisome position: 14.2

GC content: 62.72

Gene sequence:

>963_bases
ATGACGACAGTGAAGAAGATTGCCCTGGAAGAGCATTTCATGACCCCAGGTTTCCAGGCCTATTCAAAGGGATTTACGCA
ACATATCGACCCGGCGGTCTTTGCCGACCTCGGTCGCCGGCTTGCCGATTTTGACGAGCTGCGCCTCGCGGAAATGGATC
GCGCGGGCATCGATATCACCGTGCTGTCGCAGACGGGGCCGGGCGTACAGGGCGAAGCCGATTCCGAACTTGCGGTGGCG
CGCGCGCAGCAGAGCAATGACTTCCTGGCCGAACAGATTGCGCGCCATCCCACGCGCTTCGCGGGCTTTGCTGCACTGCC
CATGCACGACCCCGAACTGGCCGCCAGGGAACTCGAGCGCACGGTGCGTGAGCTCGGTTTCAAAGGCTCGCTGGTGAATG
GGCACACGCACGGGCGCTACTACGACGATCCGGCCTACGACGCATTCTGGGAGCGCATGCAATCGCTCGACGTGCCGATG
TACCTGCATCCGACCGATGCCTTTGTGAAGCCGCAGGTATTGAACGGCCATCCAGAACTCGATGGTGCCGCGTGGGGCTG
GGGCGTGGAAACTGCATCGCATGCGCTGCGCCTGCTGTTTGGCGGCGTGTTCGACCGCTTCCCGCGCCTGAAGATCATCC
TCGGCCATATGGGGGAAGGGCTGCCGTTCCAGCGCTGGCGCTTTGACAGCCGCTTTGCGGTCTATTCGCACGGCGTGCGG
CTCGCGCGCGCGCCGTCGGAGTACATCGGCAGCAATATCGTGATCACTACATCCGGCGTGTGCTCGCACGGTGCGCTGGC
CGGCGCGATTGCCGAAATGGGGCCGGAAGCAGTGATGTTCTCGGTCGACTATCCCTACGAATCCACCGAGGTTGCGGCGA
AGTTCATCGAGGAAGCGCCGCTCGACGACACGACGCGTGCGCTGGTTTGCCACGGCAACGCGCAACGCATTCTGAAGCTG
TAA

Upstream 100 bases:

>100_bases
TGTCTAGAATCCGCAATTAGTCAGTGTACTGAATAAATGACGCCGCGCCCCGGCAGAAGCGTTCGGCGCACGGTAGTCCC
TCATCAGGAGCCCCCGCAGC

Downstream 100 bases:

>100_bases
TCGCACTACGCAAGGACACCCATGCAAAAAGTCTTTCGCATCGGCCAGATCGTGCCGAGCTCCAACACCACGATGGAAAC
CGAGATCCCGGCCATGCTGA

Product: amidohydrolase 2

Products: NA

Alternate protein names: Amidohydrolase; 4-Oxalomesaconate Hydratase; Amidohydrolase/Decarboxylase; Metal-Dependent Hydrolase; Amidohydrolase Family Protein; 2-Amino-3-Carboxylmuconate-6-Semialdehyde Decarboxylase; O-Pyrocatechuate Decarboxylase; 2-Amino-3-Carboxymuconate-6-Semialdehyde Decarboxylase; Hydrolase; Amidohydrolase Family; 2-Amino-3-Carboxymuconate 6-Semialdehyde Decarboxylase; 2-Amino-3-Carboxymuconate-6- Semialdehyde Decarboxylase; Tryptophan 2 3-Dioxygenase; 2 3-Dihydroxybenzoic Acid Decarboxylase; Amidase; 5-Carboxyvanillate Decarboxylase; Metal-Dependent Hydrolase Of TIM-Barrel Fold; Barh Protein; Amidohydrolase 2 Family Protein; Decarboxylase; Metal Dependent Hydrolase; Minocarboxymuconate-Semialdehyde Decarboxylase.; 5-Carboxy-2-Hydroxymuconate-6-Semialdehyde Decarboxylase

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MTTVKKIALEEHFMTPGFQAYSKGFTQHIDPAVFADLGRRLADFDELRLAEMDRAGIDITVLSQTGPGVQGEADSELAVA
RAQQSNDFLAEQIARHPTRFAGFAALPMHDPELAARELERTVRELGFKGSLVNGHTHGRYYDDPAYDAFWERMQSLDVPM
YLHPTDAFVKPQVLNGHPELDGAAWGWGVETASHALRLLFGGVFDRFPRLKIILGHMGEGLPFQRWRFDSRFAVYSHGVR
LARAPSEYIGSNIVITTSGVCSHGALAGAIAEMGPEAVMFSVDYPYESTEVAAKFIEEAPLDDTTRALVCHGNAQRILKL

Sequences:

>Translated_320_residues
MTTVKKIALEEHFMTPGFQAYSKGFTQHIDPAVFADLGRRLADFDELRLAEMDRAGIDITVLSQTGPGVQGEADSELAVA
RAQQSNDFLAEQIARHPTRFAGFAALPMHDPELAARELERTVRELGFKGSLVNGHTHGRYYDDPAYDAFWERMQSLDVPM
YLHPTDAFVKPQVLNGHPELDGAAWGWGVETASHALRLLFGGVFDRFPRLKIILGHMGEGLPFQRWRFDSRFAVYSHGVR
LARAPSEYIGSNIVITTSGVCSHGALAGAIAEMGPEAVMFSVDYPYESTEVAAKFIEEAPLDDTTRALVCHGNAQRILKL
>Mature_319_residues
TTVKKIALEEHFMTPGFQAYSKGFTQHIDPAVFADLGRRLADFDELRLAEMDRAGIDITVLSQTGPGVQGEADSELAVAR
AQQSNDFLAEQIARHPTRFAGFAALPMHDPELAARELERTVRELGFKGSLVNGHTHGRYYDDPAYDAFWERMQSLDVPMY
LHPTDAFVKPQVLNGHPELDGAAWGWGVETASHALRLLFGGVFDRFPRLKIILGHMGEGLPFQRWRFDSRFAVYSHGVRL
ARAPSEYIGSNIVITTSGVCSHGALAGAIAEMGPEAVMFSVDYPYESTEVAAKFIEEAPLDDTTRALVCHGNAQRILKL

Specific function: Unknown

COG id: COG2159

COG function: function code R; Predicted metal-dependent hydrolase of the TIM-barrel fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI109715856, Length=312, Percent_Identity=29.8076923076923, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI71995651, Length=326, Percent_Identity=26.9938650306748, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 35390; Mature: 35259

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVKKIALEEHFMTPGFQAYSKGFTQHIDPAVFADLGRRLADFDELRLAEMDRAGIDIT
CCCHHHHHHHHHHCCCCHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VLSQTGPGVQGEADSELAVARAQQSNDFLAEQIARHPTRFAGFAALPMHDPELAARELER
EEECCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCHHHCCEEECCCCCHHHHHHHHHH
TVRELGFKGSLVNGHTHGRYYDDPAYDAFWERMQSLDVPMYLHPTDAFVKPQVLNGHPEL
HHHHCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCHHCCCCCCC
DGAAWGWGVETASHALRLLFGGVFDRFPRLKIILGHMGEGLPFQRWRFDSRFAVYSHGVR
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHCCCCCEEHHHCCEE
LARAPSEYIGSNIVITTSGVCSHGALAGAIAEMGPEAVMFSVDYPYESTEVAAKFIEEAP
EECCCHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCC
LDDTTRALVCHGNAQRILKL
CCCCCEEEEEECCHHHHHCC
>Mature Secondary Structure 
TTVKKIALEEHFMTPGFQAYSKGFTQHIDPAVFADLGRRLADFDELRLAEMDRAGIDIT
CCHHHHHHHHHHCCCCHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VLSQTGPGVQGEADSELAVARAQQSNDFLAEQIARHPTRFAGFAALPMHDPELAARELER
EEECCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCHHHCCEEECCCCCHHHHHHHHHH
TVRELGFKGSLVNGHTHGRYYDDPAYDAFWERMQSLDVPMYLHPTDAFVKPQVLNGHPEL
HHHHCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCHHCCCCCCC
DGAAWGWGVETASHALRLLFGGVFDRFPRLKIILGHMGEGLPFQRWRFDSRFAVYSHGVR
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHCCCCCEEHHHCCEE
LARAPSEYIGSNIVITTSGVCSHGALAGAIAEMGPEAVMFSVDYPYESTEVAAKFIEEAP
EECCCHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCC
LDDTTRALVCHGNAQRILKL
CCCCCEEEEEECCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA