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The map label for this gene is glpR [H]

Identifier: 73537557

GI number: 73537557

Start: 312170

End: 312925

Strand: Direct

Name: glpR [H]

Synonym: Reut_B3722

Alternate gene names: 73537557

Gene position: 312170-312925 (Clockwise)

Preceding gene: 73537556

Following gene: 73537559

Centisome position: 11.45

GC content: 67.06

Gene sequence:

>756_bases
GTGCTGGCCGAACAGCGGCAGAAACACATCCTAAATCAGCTTGCCGCGACCGGTGCGCTGGCTATCAGCGCGCTGGTCAC
GGAACTCGGCGTCTCGCGCGAGACCATACGGCGCGACCTCAACGCATTGGCCGAACGCGGCCTGCTGGTGCTGACCCATG
GTGGCGCGCTGGCGCCGAACCGAACCGAGCCCGACACCCAGACCCGTGCCGCGATCAACGCCGAAGGCAAGCGCGCCATC
GGCCAGCGTGCGGCGGAGCTGGTGCCGGACGGCGCGTCGCTGATCCTCGACTACGGCACCACTACCCACGCCGTGGCGCA
GGCGCTGCAAGGCCATCACAACCTGCTGGTCTATACCAACGACCTGTCGATCGCGCTGCTGCTCGGCCGGCGCAACGGCA
ACCGCGTAATCGTGCTCGGCGGGGAACTGCAGGACAACGAGGACGCGACCCACGGGTGGGACACCATCGAGCAGGTCTCT
CGCTATCACACCGACTTTGCTTTTGTCGGCATCGGCGGCGTAACGCCGCGCGGCGAAATCTGCGACTTTTCGCGTGGTGC
GGCGGAACTGCGCAGCCGCATGCTGCTGGCCGCCGATGTCGCCTGCGTGCTGGCCGACTATACGAAGTTCGGCCGCAACA
CGGGCGTGAACATCCGGCACTTCGATCAGGCCGCGTGGCTGATCACCGATATGGCACCCGAGCCGCCGCTGGCCGAAGCG
CTGCGGCAGGCGGGGCCGAAACTGCTGATTGCCTGA

Upstream 100 bases:

>100_bases
CCTGGGGCTGAGCGCGGCGGCTGCCGGGCGGCTGCAAGGCCGGACCCTGGCGGCCTTCGGCTAGAATCGGCGCACTTGTC
CGTCCCTTCCGGAGTCCACT

Downstream 100 bases:

>100_bases
CCCCCGCGGGCAAGCCCGCGGGGCTACTGGTAATCAAACGTGAATGTCATTGCGCCACTGACCACGCCAGGCTTCGCATG
CGGGGCCAGTGCGAAGTATC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLAEQRQKHILNQLAATGALAISALVTELGVSRETIRRDLNALAERGLLVLTHGGALAPNRTEPDTQTRAAINAEGKRAI
GQRAAELVPDGASLILDYGTTTHAVAQALQGHHNLLVYTNDLSIALLLGRRNGNRVIVLGGELQDNEDATHGWDTIEQVS
RYHTDFAFVGIGGVTPRGEICDFSRGAAELRSRMLLAADVACVLADYTKFGRNTGVNIRHFDQAAWLITDMAPEPPLAEA
LRQAGPKLLIA

Sequences:

>Translated_251_residues
MLAEQRQKHILNQLAATGALAISALVTELGVSRETIRRDLNALAERGLLVLTHGGALAPNRTEPDTQTRAAINAEGKRAI
GQRAAELVPDGASLILDYGTTTHAVAQALQGHHNLLVYTNDLSIALLLGRRNGNRVIVLGGELQDNEDATHGWDTIEQVS
RYHTDFAFVGIGGVTPRGEICDFSRGAAELRSRMLLAADVACVLADYTKFGRNTGVNIRHFDQAAWLITDMAPEPPLAEA
LRQAGPKLLIA
>Mature_251_residues
MLAEQRQKHILNQLAATGALAISALVTELGVSRETIRRDLNALAERGLLVLTHGGALAPNRTEPDTQTRAAINAEGKRAI
GQRAAELVPDGASLILDYGTTTHAVAQALQGHHNLLVYTNDLSIALLLGRRNGNRVIVLGGELQDNEDATHGWDTIEQVS
RYHTDFAFVGIGGVTPRGEICDFSRGAAELRSRMLLAADVACVLADYTKFGRNTGVNIRHFDQAAWLITDMAPEPPLAEA
LRQAGPKLLIA

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=242, Percent_Identity=33.0578512396694, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1789519, Length=250, Percent_Identity=28.8, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI87082344, Length=246, Percent_Identity=29.2682926829268, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI226510968, Length=256, Percent_Identity=31.640625, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1789059, Length=252, Percent_Identity=27.7777777777778, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788069, Length=236, Percent_Identity=27.9661016949153, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1789170, Length=229, Percent_Identity=29.2576419213974, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790635, Length=253, Percent_Identity=28.8537549407115, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787540, Length=226, Percent_Identity=29.646017699115, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787063, Length=238, Percent_Identity=24.7899159663866, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 26980; Mature: 26980

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAEQRQKHILNQLAATGALAISALVTELGVSRETIRRDLNALAERGLLVLTHGGALAPN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCCCCC
RTEPDTQTRAAINAEGKRAIGQRAAELVPDGASLILDYGTTTHAVAQALQGHHNLLVYTN
CCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHCCCCEEEEEEC
DLSIALLLGRRNGNRVIVLGGELQDNEDATHGWDTIEQVSRYHTDFAFVGIGGVTPRGEI
CCEEEEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCC
CDFSRGAAELRSRMLLAADVACVLADYTKFGRNTGVNIRHFDQAAWLITDMAPEPPLAEA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHEEEECCCCCCCHHHH
LRQAGPKLLIA
HHHCCCEEECC
>Mature Secondary Structure
MLAEQRQKHILNQLAATGALAISALVTELGVSRETIRRDLNALAERGLLVLTHGGALAPN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCCCCC
RTEPDTQTRAAINAEGKRAIGQRAAELVPDGASLILDYGTTTHAVAQALQGHHNLLVYTN
CCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHCCCCEEEEEEC
DLSIALLLGRRNGNRVIVLGGELQDNEDATHGWDTIEQVSRYHTDFAFVGIGGVTPRGEI
CCEEEEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCC
CDFSRGAAELRSRMLLAADVACVLADYTKFGRNTGVNIRHFDQAAWLITDMAPEPPLAEA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHEEEECCCCCCCHHHH
LRQAGPKLLIA
HHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]