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The map label for this gene is vgb [H]

Identifier: 73537515

GI number: 73537515

Start: 261255

End: 262250

Strand: Direct

Name: vgb [H]

Synonym: Reut_B3680

Alternate gene names: 73537515

Gene position: 261255-262250 (Clockwise)

Preceding gene: 73537510

Following gene: 73537522

Centisome position: 9.58

GC content: 66.67

Gene sequence:

>996_bases
ATGCCCCTGCGCTCGCTCCGCGCCGTACTGGCTGCCGGCATCATGGCCGTGTCGGTCACCACGGTCTGTGCCCAGGGCAC
AGTGCCACCACGCGTCCAGAGCTATCCAGTGCCGGCCGGCGCGCATCCGCACGACGTTGCGCCCGCGCCCGATGGCGCGG
TGTGGTACACGGCCCAGAGCACGGGCGAGCTCGGGCGGTTGGACCCCGCAACCGGCAAGACCATCCATATCCCGCTCGGC
GAAGCCTCCGCGCCGCATGGCGTGATCATCGGACCCGATGGTGCTGCGTGGGTGACGGACGGCGGCCAGAACGCGATCCT
GCGGGTCGACCCCGGAACCCATGGCGTGAAGCGTTTTCCGCTCCCTGCCGGACAGGCCAATGTCAATCTGAATACCGCCG
TGTTCGATACGCGCGGACGTCTGTGGTTCACGGGGCAGAACGGGGTCTACGGTGAACTGGACCCCGCCAGCGGCCACATG
CGCATGTTCGATGCGCCGCGAGGCCGGGGCCCGTACGGCATTGCCGTGACGCCGAAAGGCGATGTCTATTTCGCCTCGCT
GGCCGGGGATTACATTGCCCGCATCGACACCGCCACCGGCGCCGCGCAGGTCATGACGCCACCCACGCCAAAGTCAGGGC
CGCGCCGCATCTGGTCCGACTCGAAGGGGACGCTGTGGATCAGCGAATGGACCGCCGGCAAGCTGGGCGCCTATGATCCC
GGCACGGCCCGCTGGCGGGAATGGAAGCTGCCAGGCGATAGTCCGCATGCCTATGCGATGTATGTGGATGAGCAGGACAA
GGTGTGGCTAAGCGACTGGGGCAGGAATGCCGTGCTGCGCTTCGACCCGCAGGCCGGCAAGTTCGAGACCTTTACCAGTC
CACGGCCGGATGCCAATGTGCGACAGATGTTGGGTCGACCGGGAGAAGCGTGGGCGGCGGAGTCAGGTACGGATCATCTG
GTTGTCTATCGCTTCGGCACTGGTGCGCCAAGATGA

Upstream 100 bases:

>100_bases
TGGAGGATCAATCGCGCAGTATACGGGCACGCGTGTCCCCGTCTGGCCGTGGCTGGCCTATGCTTGGATCGAAGTTTCTT
GGACTGATCAGGAGATGGCG

Downstream 100 bases:

>100_bases
ACCTGCGGACAGGATGTCGACTGCCCTGCGCGTCTATGCGCGATCCACCGGCCGGGGCGAGATAAGCGGGGCGCGCCGGC
GCTGCAGCACAATCATGGGT

Product: putative hydrolase transmembrane protein

Products: NA

Alternate protein names: Streptogramin B lyase [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MPLRSLRAVLAAGIMAVSVTTVCAQGTVPPRVQSYPVPAGAHPHDVAPAPDGAVWYTAQSTGELGRLDPATGKTIHIPLG
EASAPHGVIIGPDGAAWVTDGGQNAILRVDPGTHGVKRFPLPAGQANVNLNTAVFDTRGRLWFTGQNGVYGELDPASGHM
RMFDAPRGRGPYGIAVTPKGDVYFASLAGDYIARIDTATGAAQVMTPPTPKSGPRRIWSDSKGTLWISEWTAGKLGAYDP
GTARWREWKLPGDSPHAYAMYVDEQDKVWLSDWGRNAVLRFDPQAGKFETFTSPRPDANVRQMLGRPGEAWAAESGTDHL
VVYRFGTGAPR

Sequences:

>Translated_331_residues
MPLRSLRAVLAAGIMAVSVTTVCAQGTVPPRVQSYPVPAGAHPHDVAPAPDGAVWYTAQSTGELGRLDPATGKTIHIPLG
EASAPHGVIIGPDGAAWVTDGGQNAILRVDPGTHGVKRFPLPAGQANVNLNTAVFDTRGRLWFTGQNGVYGELDPASGHM
RMFDAPRGRGPYGIAVTPKGDVYFASLAGDYIARIDTATGAAQVMTPPTPKSGPRRIWSDSKGTLWISEWTAGKLGAYDP
GTARWREWKLPGDSPHAYAMYVDEQDKVWLSDWGRNAVLRFDPQAGKFETFTSPRPDANVRQMLGRPGEAWAAESGTDHL
VVYRFGTGAPR
>Mature_330_residues
PLRSLRAVLAAGIMAVSVTTVCAQGTVPPRVQSYPVPAGAHPHDVAPAPDGAVWYTAQSTGELGRLDPATGKTIHIPLGE
ASAPHGVIIGPDGAAWVTDGGQNAILRVDPGTHGVKRFPLPAGQANVNLNTAVFDTRGRLWFTGQNGVYGELDPASGHMR
MFDAPRGRGPYGIAVTPKGDVYFASLAGDYIARIDTATGAAQVMTPPTPKSGPRRIWSDSKGTLWISEWTAGKLGAYDPG
TARWREWKLPGDSPHAYAMYVDEQDKVWLSDWGRNAVLRFDPQAGKFETFTSPRPDANVRQMLGRPGEAWAAESGTDHLV
VYRFGTGAPR

Specific function: Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid [H]

COG id: COG4257

COG function: function code V; Streptogramin lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the vgb family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 35359; Mature: 35228

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLRSLRAVLAAGIMAVSVTTVCAQGTVPPRVQSYPVPAGAHPHDVAPAPDGAVWYTAQS
CCHHHHHHHHHHHHHHEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECC
TGELGRLDPATGKTIHIPLGEASAPHGVIIGPDGAAWVTDGGQNAILRVDPGTHGVKRFP
CCCCCCCCCCCCCEEEEECCCCCCCCCEEECCCCCEEEECCCCEEEEEECCCCCCCEECC
LPAGQANVNLNTAVFDTRGRLWFTGQNGVYGELDPASGHMRMFDAPRGRGPYGIAVTPKG
CCCCCCCEEEEEEEEECCCCEEEEECCCCEEEECCCCCCEEEEECCCCCCCEEEEECCCC
DVYFASLAGDYIARIDTATGAAQVMTPPTPKSGPRRIWSDSKGTLWISEWTAGKLGAYDP
CEEEEEECCCEEEEEECCCCCEEEECCCCCCCCCCHHCCCCCCEEEEEECCCCCCCCCCC
GTARWREWKLPGDSPHAYAMYVDEQDKVWLSDWGRNAVLRFDPQAGKFETFTSPRPDANV
CCCCEEEECCCCCCCCEEEEEECCCCCEEEECCCCCEEEEECCCCCCEECCCCCCCCHHH
RQMLGRPGEAWAAESGTDHLVVYRFGTGAPR
HHHHCCCCCCEECCCCCCEEEEEEECCCCCC
>Mature Secondary Structure 
PLRSLRAVLAAGIMAVSVTTVCAQGTVPPRVQSYPVPAGAHPHDVAPAPDGAVWYTAQS
CHHHHHHHHHHHHHHEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECC
TGELGRLDPATGKTIHIPLGEASAPHGVIIGPDGAAWVTDGGQNAILRVDPGTHGVKRFP
CCCCCCCCCCCCCEEEEECCCCCCCCCEEECCCCCEEEECCCCEEEEEECCCCCCCEECC
LPAGQANVNLNTAVFDTRGRLWFTGQNGVYGELDPASGHMRMFDAPRGRGPYGIAVTPKG
CCCCCCCEEEEEEEEECCCCEEEEECCCCEEEECCCCCCEEEEECCCCCCCEEEEECCCC
DVYFASLAGDYIARIDTATGAAQVMTPPTPKSGPRRIWSDSKGTLWISEWTAGKLGAYDP
CEEEEEECCCEEEEEECCCCCEEEECCCCCCCCCCHHCCCCCCEEEEEECCCCCCCCCCC
GTARWREWKLPGDSPHAYAMYVDEQDKVWLSDWGRNAVLRFDPQAGKFETFTSPRPDANV
CCCCEEEECCCCCCCCEEEEEECCCCCEEEECCCCCEEEEECCCCCCEECCCCCCCCHHH
RQMLGRPGEAWAAESGTDHLVVYRFGTGAPR
HHHHCCCCCCEECCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA