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The map label for this gene is pcaR [H]

Identifier: 73537497

GI number: 73537497

Start: 241180

End: 242109

Strand: Direct

Name: pcaR [H]

Synonym: Reut_B3662

Alternate gene names: 73537497

Gene position: 241180-242109 (Clockwise)

Preceding gene: 73537490

Following gene: 73537498

Centisome position: 8.85

GC content: 69.57

Gene sequence:

>930_bases
ATGAAGCGCTCGACCTCCATCCCGGCACCACCGCCCGACGCGGCCCATGTCATGCCCGCCATGCCGTGCGCTGCCGCCCA
TCTTGCCCATAACGCCTATACCGCCGACGACCGCAACTTCGTCACCGCGCTGGCGCGCGGCATGGAGTTGCTGCGCGCGT
TCGGCCCCCACGACGACTATCTCGGTAATGCGGAGCTGTCCCGGCGCACCGGCATTCCGCGGCCCACGGTGTCGCGGCTG
ACCTATACGCTGGCTTCGCTCGGCTATCTCTCTTACATCGAATCGATGGAGAAGTACCGGCTTGGGCAAGGCGCGATGGT
GCTCGGGCACCGCTACATTTCCGGCGCGGGCATCCGCGATATCGCGCAGCCGCTGATGCAATCGCTCGCATTTGCGACGG
ACTGCACGGTTGCGCTGGCCATGCCCGACCGCCATGCGATGGTCTATCTGGAATCGTGCCAGCCGCGCGGCGCGCTGGTG
ATCCGGCTCGCGCCCGGCGCGCGGCTGCCGATGGCCACGTCGGCCATGGGGCGCGCGTGGCTAGCGGGGCTCGACAGCGC
GCACCGAGAAGCGGCACTGGCCGAACTGGAGCGCCACTATGGCGCGCGCTGGGCGTCGGTGCGCAGCAAGATCGAGCGCT
CGTTGCGCGACCACGCGCGGCGCGGCTTCTGCGTGGCGCATGCCGAGTGGGACCGCACTGTCAGCGGCGCGGCGGCGCCG
CTTCGGCTCGAAGGCAGCGGCGAGGTGCTGGCGCTGAACATCGGCGGCGCCGCGACGCGTCTGTCGCCGGAAATCCTGGA
AAGCAACCTGGGCCCGCGCATTCGCGATCTTGCGCAGACGCTGCAGGCGCGGCTGTGGCAGGCCGGTGCCGGACGGCAGG
GATCGACACGTACGGCGGCGGCAACGTCCGACGCCTGTGAATCAAACTGA

Upstream 100 bases:

>100_bases
TACCATCCATGGCACCTATGACCCCTATGTTTTAGGTACATAGCCGGTGCTGCGGTCCCGGGAACTGGTATCTAGTCAGT
CAGGACAACGCCCAGCCCGC

Downstream 100 bases:

>100_bases
GCAAACCATCAAGCAGAGATAAGGAGACAACGCATGCAAGTCAAAGACAAGACCGTCGTCGTGACGGGCGCCGCCACGGG
CATCGGCCGCGCGCTGGCGC

Product: regulatory protein IclR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MKRSTSIPAPPPDAAHVMPAMPCAAAHLAHNAYTADDRNFVTALARGMELLRAFGPHDDYLGNAELSRRTGIPRPTVSRL
TYTLASLGYLSYIESMEKYRLGQGAMVLGHRYISGAGIRDIAQPLMQSLAFATDCTVALAMPDRHAMVYLESCQPRGALV
IRLAPGARLPMATSAMGRAWLAGLDSAHREAALAELERHYGARWASVRSKIERSLRDHARRGFCVAHAEWDRTVSGAAAP
LRLEGSGEVLALNIGGAATRLSPEILESNLGPRIRDLAQTLQARLWQAGAGRQGSTRTAAATSDACESN

Sequences:

>Translated_309_residues
MKRSTSIPAPPPDAAHVMPAMPCAAAHLAHNAYTADDRNFVTALARGMELLRAFGPHDDYLGNAELSRRTGIPRPTVSRL
TYTLASLGYLSYIESMEKYRLGQGAMVLGHRYISGAGIRDIAQPLMQSLAFATDCTVALAMPDRHAMVYLESCQPRGALV
IRLAPGARLPMATSAMGRAWLAGLDSAHREAALAELERHYGARWASVRSKIERSLRDHARRGFCVAHAEWDRTVSGAAAP
LRLEGSGEVLALNIGGAATRLSPEILESNLGPRIRDLAQTLQARLWQAGAGRQGSTRTAAATSDACESN
>Mature_309_residues
MKRSTSIPAPPPDAAHVMPAMPCAAAHLAHNAYTADDRNFVTALARGMELLRAFGPHDDYLGNAELSRRTGIPRPTVSRL
TYTLASLGYLSYIESMEKYRLGQGAMVLGHRYISGAGIRDIAQPLMQSLAFATDCTVALAMPDRHAMVYLESCQPRGALV
IRLAPGARLPMATSAMGRAWLAGLDSAHREAALAELERHYGARWASVRSKIERSLRDHARRGFCVAHAEWDRTVSGAAAP
LRLEGSGEVLALNIGGAATRLSPEILESNLGPRIRDLAQTLQARLWQAGAGRQGSTRTAAATSDACESN

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=146, Percent_Identity=25.3424657534247, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789999, Length=251, Percent_Identity=27.4900398406374, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 33236; Mature: 33236

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSTSIPAPPPDAAHVMPAMPCAAAHLAHNAYTADDRNFVTALARGMELLRAFGPHDDY
CCCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
LGNAELSRRTGIPRPTVSRLTYTLASLGYLSYIESMEKYRLGQGAMVLGHRYISGAGIRD
CCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCHHH
IAQPLMQSLAFATDCTVALAMPDRHAMVYLESCQPRGALVIRLAPGARLPMATSAMGRAW
HHHHHHHHHHHHHCCEEEEECCCCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHH
LAGLDSAHREAALAELERHYGARWASVRSKIERSLRDHARRGFCVAHAEWDRTVSGAAAP
HHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCC
LRLEGSGEVLALNIGGAATRLSPEILESNLGPRIRDLAQTLQARLWQAGAGRQGSTRTAA
EEECCCCCEEEEECCCCHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
ATSDACESN
CCCHHCCCC
>Mature Secondary Structure
MKRSTSIPAPPPDAAHVMPAMPCAAAHLAHNAYTADDRNFVTALARGMELLRAFGPHDDY
CCCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
LGNAELSRRTGIPRPTVSRLTYTLASLGYLSYIESMEKYRLGQGAMVLGHRYISGAGIRD
CCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCHHH
IAQPLMQSLAFATDCTVALAMPDRHAMVYLESCQPRGALVIRLAPGARLPMATSAMGRAW
HHHHHHHHHHHHHCCEEEEECCCCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHH
LAGLDSAHREAALAELERHYGARWASVRSKIERSLRDHARRGFCVAHAEWDRTVSGAAAP
HHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCC
LRLEGSGEVLALNIGGAATRLSPEILESNLGPRIRDLAQTLQARLWQAGAGRQGSTRTAA
EEECCCCCEEEEECCCCHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
ATSDACESN
CCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]