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The map label for this gene is ndhS [H]

Identifier: 73537431

GI number: 73537431

Start: 155752

End: 156228

Strand: Direct

Name: ndhS [H]

Synonym: Reut_B3596

Alternate gene names: 73537431

Gene position: 155752-156228 (Clockwise)

Preceding gene: 73537430

Following gene: 73537432

Centisome position: 5.71

GC content: 64.57

Gene sequence:

>477_bases
ATGAACAAAGTCACCATCGATGTCACCGTCAACGGTGAAGAACATACCGTCGAGGTCCCCGCACGGCGCATGCTGTCCGA
CCTGCTGCGCGACGACCTGAACTTGACCGGCACCAAGCGCGGCTGCGAAACCGGCATCTGCGGCGCCTGCACGGTGCTGG
TGGATGGCGAGGCCGTCAAGTCCTGCCTGATGCTGGCCGCGCAGGTGCGTGGCCGCCACGTGATGACCGTCGAAGGCCTG
GCCGCAGACGGCGAGCTGCATCCGCTGCAGCAGTGCTTCATGGAGTGCGGCGGGCTGCAGTGTGGCTACTGCACGCCGGG
CTTCCTGATGACGTCGTGCGCGCTGCTGGCCAACAACCCCAACCCAACGGAAGAGGAAGTCCGCCACGGCCTGAACGGCA
ACCTGTGCCGCTGCACGGGCTATGTCGGCATCGTCGAATCCATCCTGTCCGCCGCGGAGAAAATGCGTGGAAATTGA

Upstream 100 bases:

>100_bases
CATGCGCGGCACGGAGGATTTCCGCCGCCATATCGTGCGCACGGTCGCACGCCGCACCATCGCCGATCTGTTCGGCGTGG
CCGCGGACTGAGGAGTCGCC

Downstream 100 bases:

>100_bases
AAAGACCCTGGTCACCGCGGTGCCGCCGGCACGCGTGTGGGAACTGATGCTTGACCCGAACGTGATGGGCGCCTGCGTGC
CCGGCATGGAATCGATCGAG

Product: ferredoxin

Products: NA

Alternate protein names: NDH; Nicotinic acid hydroxylase small FeS subunit; NAH [H]

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MNKVTIDVTVNGEEHTVEVPARRMLSDLLRDDLNLTGTKRGCETGICGACTVLVDGEAVKSCLMLAAQVRGRHVMTVEGL
AADGELHPLQQCFMECGGLQCGYCTPGFLMTSCALLANNPNPTEEEVRHGLNGNLCRCTGYVGIVESILSAAEKMRGN

Sequences:

>Translated_158_residues
MNKVTIDVTVNGEEHTVEVPARRMLSDLLRDDLNLTGTKRGCETGICGACTVLVDGEAVKSCLMLAAQVRGRHVMTVEGL
AADGELHPLQQCFMECGGLQCGYCTPGFLMTSCALLANNPNPTEEEVRHGLNGNLCRCTGYVGIVESILSAAEKMRGN
>Mature_158_residues
MNKVTIDVTVNGEEHTVEVPARRMLSDLLRDDLNLTGTKRGCETGICGACTVLVDGEAVKSCLMLAAQVRGRHVMTVEGL
AADGELHPLQQCFMECGGLQCGYCTPGFLMTSCALLANNPNPTEEEVRHGLNGNLCRCTGYVGIVESILSAAEKMRGN

Specific function: Catalyzes the hydroxylation of nicotinate to 6- hydroxynicotinate. Also active against 2-pyrazinecarboxylic acid, but inactive against other nicotinate analogs [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=88, Percent_Identity=43.1818181818182, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI91823271, Length=135, Percent_Identity=40.7407407407407, Blast_Score=84, Evalue=6e-17,
Organism=Escherichia coli, GI1789232, Length=148, Percent_Identity=47.972972972973, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI1786480, Length=166, Percent_Identity=39.7590361445783, Blast_Score=129, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17540638, Length=154, Percent_Identity=48.0519480519481, Blast_Score=138, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17539860, Length=161, Percent_Identity=40.3726708074534, Blast_Score=124, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32566215, Length=159, Percent_Identity=39.622641509434, Blast_Score=122, Evalue=6e-29,
Organism=Drosophila melanogaster, GI17737937, Length=158, Percent_Identity=39.873417721519, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24647193, Length=160, Percent_Identity=38.125, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24647201, Length=153, Percent_Identity=37.2549019607843, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24647199, Length=158, Percent_Identity=36.0759493670886, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24647197, Length=164, Percent_Identity=35.9756097560976, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24647195, Length=164, Percent_Identity=35.9756097560976, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.17.1.5 [H]

Molecular weight: Translated: 16888; Mature: 16888

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
11.4 %Cys+Met (Translated Protein)
7.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
11.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVTIDVTVNGEEHTVEVPARRMLSDLLRDDLNLTGTKRGCETGICGACTVLVDGEAVK
CCEEEEEEEECCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCHHHH
SCLMLAAQVRGRHVMTVEGLAADGELHPLQQCFMECGGLQCGYCTPGFLMTSCALLANNP
HHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCC
NPTEEEVRHGLNGNLCRCTGYVGIVESILSAAEKMRGN
CCCHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKVTIDVTVNGEEHTVEVPARRMLSDLLRDDLNLTGTKRGCETGICGACTVLVDGEAVK
CCEEEEEEEECCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCHHHH
SCLMLAAQVRGRHVMTVEGLAADGELHPLQQCFMECGGLQCGYCTPGFLMTSCALLANNP
HHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCC
NPTEEEVRHGLNGNLCRCTGYVGIVESILSAAEKMRGN
CCCHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA