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The map label for this gene is hcrA [H]

Identifier: 73537429

GI number: 73537429

Start: 152559

End: 154883

Strand: Direct

Name: hcrA [H]

Synonym: Reut_B3594

Alternate gene names: 73537429

Gene position: 152559-154883 (Clockwise)

Preceding gene: 73537428

Following gene: 73537430

Centisome position: 5.6

GC content: 67.27

Gene sequence:

>2325_bases
ATGCAACACAAGACGCAGGAGGCGGGCATGAGCGAGTCCATCGTGGGAGCGTCCACGCCGCAGGTGACCGCGCGGGAGAA
GGTCATGGGACGCGCGCAGTATGCCGGCGATATCAAGCTACCCGGCATGCTGCATGCGAAGGTGCTGCGCAGCCCGCACC
CGCATGCGCGCATCGTCAGCATCGATACCGCGGCGGCGAAGGCGCTGCCCGGTGTCAAGCTGGTGGTGACCGGGCGCGAT
ACGCCCACGCGCCTGTGGGGGCCGCACCGCAAGGAGCAGCGCATCCTCGCTGTCGGCGTGGTGCTCCACGTCGGCGAGGA
AGTGGCGGCCGTGGTCGCGGTCAGCGAGGAAATCGCGCGCGATGCGCTCGACCTGATCCGCGTCGCGTACGAGGAACTGC
CTGCGCTGCTGAGCCCCGAGGCTGCCCTGGCCGACGGGGCGCCGGAAGTCCATGCCGGCACGCGCAATATCGGCCATGAG
ATGCATATCGAGCGCGGCGACGTGGAGGCCGGTTTTGCCGAGGCCGCCGCGGTGTACGAGGCCACGTACGACATGCATTC
GCAGTACCCGGGCTATCTGGAGCCGATGGCCTCCGTCGCGACGCAGGACGGCAACGGGCGCCTGACGGTGTACGCGTCGA
CGCAGTCGGTGTTCCTCGCGCGCAGCCGCCTGGCAGAGGCGCTCGACCGTCCGGCCTCGACAATCCGCGTGGTGCAGGCG
ACTACGGGCGGCGGCTTCGGCGCGAAGATCGTCGAGGAGAACAACAGCCTGATCTGCGCGTTCCTGGCGACGAAGCTCGA
TCGCCCGGTGCGGATGGTCAACAACCGCCTCGAAGATTTCCAGGGCGCGCGCGCAAGCGTGCCGGCAAAGGTGTGGCTGC
GCATCGGCCTGTCGGCCAACGGCATGATCGTGGCCAAGGATGTGCGTATCACGGCCGAGTGCGGCGCGTATGCGGGCCTG
GCCGGCGACGTCATGCACGTCAGCGCCATGCGCAGCGACAACATGCATCGCGTGACCAACGTGCGATCGCATGCGGTGCT
CGCGTACACCAACAACCCGCCGCGAGGTGCATTCCGCGGCTTCGGTGGGCAACAGATGCAGTTCCCGCTGAACTGCCATC
TGACGGTGCTGGCAGGGATGATCGGCATGGACCCGATTGAAGTGCACAAGCGCAATGCGATCGGCCGCGGCGAGACCAGC
GTGCATGGCTGGCAGATCGGCAGCACGGGCATGCAGGAATGCCTGGAGATGACGCGCAAGGCAATCGGCTGGGATGCGAA
GCGAGAGGCCCCGCGTGGCACCGGCACGCGCCGGCGCGGCGTGGGCATCGCCGCCGCGATGCACGTCAGCGGCAACCGCA
CGCTCGGCAACTGGGATGGCTCGACCATCCTGCTCAAGCTCAATGAAGATGGCCGCGTGATGCTGCAGACCAGCGAATGC
GACATGGGGCAGGGCGCCAACACGATGCTGAGTCAGATCTGCGCGCAGGAGATGGGCATTCCGCTGTCGCACGTGACCGT
GATGGCGCCGGATACCGATACCTCGCCGTTCTGCCTGGGCTCGCTGGCGTCGCGCGTGACGATCATCTCGGGCAATGCCG
TGCTGCGTGCTGCGCGCGAAGCGAAGCAGAAGGTGATGGCGCTGGCGGCCGAGAAGTTCGGCGTGGATGCGGACAGCCTG
GTGTTTGCCGATGGCCGCATCAGCGTGCCGGGCCAGCCGGACAAGTCGGCCACGCTCGCTGAAATCGCACGGCTCCATAT
CTTCCGCCATGGCGGCGAGGGCATCCATGTGCGCGCCACCTATGACGCGCCCACCGTGATGCACGACGCCAACTACTACG
GCAACATTGCGCCCGCCTATTCGTTCGCGGCGCAGGCGGTGGAAGTGGAGGTCGATACCTGCACGGGCCGCGTGACCGTG
ATCGACAGCTTTGTCGCCGATGACTGCGGCAAGGCCATCAACCCGCTCGCGGTGCACGGCCAGACGCACGGTGCCACGGT
GCAGGCAATCGGCTGGACGCTCTACGAGCACCTGCGCTACGAAGACGGCCGGCTGCAGAACGGCAACTTCGCCGACTACA
CCATGGCCACGGCCGATGCGCTGCCGATGCTGCGCACCGACCTCGTCGAGTCGAACGATCCCAATGGCCCGTTCGGCGCC
AAGGGCGCAAGCGAGACGGCAATCCTGCCCGGCGCGGCGGCGATTGCCAACGCGGTGTATCACGCGATCGGCGTGCGCAT
CCATTCGCTGCCGATCACGCCCGAGAAGGTGCTGGCCGCATTGCGCGAGCGCGAAGAGATGGAGAAGGAGAGCGCCCATG
CGTGA

Upstream 100 bases:

>100_bases
TCGGCGCTCGACAAGGTCAATGCTTCGGACTATGAGCGCCTGGGCAGGGTGATCCGCGACATGGGCATCTCGGCGGAATG
ACGCAAGGCGCAGCAGATCC

Downstream 100 bases:

>100_bases
TTTCGAATTCCTGGAGCCGGCTACGGTCGGCGAAGCCAGCCGCATGCTGGCCGACCTCGGGGACAACTGCCGCGCGTATG
CGGGCGGCACGGCGCTGATG

Product: xanthine dehydrogenase, molybdenum binding subunit apoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 774; Mature: 774

Protein sequence:

>774_residues
MQHKTQEAGMSESIVGASTPQVTAREKVMGRAQYAGDIKLPGMLHAKVLRSPHPHARIVSIDTAAAKALPGVKLVVTGRD
TPTRLWGPHRKEQRILAVGVVLHVGEEVAAVVAVSEEIARDALDLIRVAYEELPALLSPEAALADGAPEVHAGTRNIGHE
MHIERGDVEAGFAEAAAVYEATYDMHSQYPGYLEPMASVATQDGNGRLTVYASTQSVFLARSRLAEALDRPASTIRVVQA
TTGGGFGAKIVEENNSLICAFLATKLDRPVRMVNNRLEDFQGARASVPAKVWLRIGLSANGMIVAKDVRITAECGAYAGL
AGDVMHVSAMRSDNMHRVTNVRSHAVLAYTNNPPRGAFRGFGGQQMQFPLNCHLTVLAGMIGMDPIEVHKRNAIGRGETS
VHGWQIGSTGMQECLEMTRKAIGWDAKREAPRGTGTRRRGVGIAAAMHVSGNRTLGNWDGSTILLKLNEDGRVMLQTSEC
DMGQGANTMLSQICAQEMGIPLSHVTVMAPDTDTSPFCLGSLASRVTIISGNAVLRAAREAKQKVMALAAEKFGVDADSL
VFADGRISVPGQPDKSATLAEIARLHIFRHGGEGIHVRATYDAPTVMHDANYYGNIAPAYSFAAQAVEVEVDTCTGRVTV
IDSFVADDCGKAINPLAVHGQTHGATVQAIGWTLYEHLRYEDGRLQNGNFADYTMATADALPMLRTDLVESNDPNGPFGA
KGASETAILPGAAAIANAVYHAIGVRIHSLPITPEKVLAALREREEMEKESAHA

Sequences:

>Translated_774_residues
MQHKTQEAGMSESIVGASTPQVTAREKVMGRAQYAGDIKLPGMLHAKVLRSPHPHARIVSIDTAAAKALPGVKLVVTGRD
TPTRLWGPHRKEQRILAVGVVLHVGEEVAAVVAVSEEIARDALDLIRVAYEELPALLSPEAALADGAPEVHAGTRNIGHE
MHIERGDVEAGFAEAAAVYEATYDMHSQYPGYLEPMASVATQDGNGRLTVYASTQSVFLARSRLAEALDRPASTIRVVQA
TTGGGFGAKIVEENNSLICAFLATKLDRPVRMVNNRLEDFQGARASVPAKVWLRIGLSANGMIVAKDVRITAECGAYAGL
AGDVMHVSAMRSDNMHRVTNVRSHAVLAYTNNPPRGAFRGFGGQQMQFPLNCHLTVLAGMIGMDPIEVHKRNAIGRGETS
VHGWQIGSTGMQECLEMTRKAIGWDAKREAPRGTGTRRRGVGIAAAMHVSGNRTLGNWDGSTILLKLNEDGRVMLQTSEC
DMGQGANTMLSQICAQEMGIPLSHVTVMAPDTDTSPFCLGSLASRVTIISGNAVLRAAREAKQKVMALAAEKFGVDADSL
VFADGRISVPGQPDKSATLAEIARLHIFRHGGEGIHVRATYDAPTVMHDANYYGNIAPAYSFAAQAVEVEVDTCTGRVTV
IDSFVADDCGKAINPLAVHGQTHGATVQAIGWTLYEHLRYEDGRLQNGNFADYTMATADALPMLRTDLVESNDPNGPFGA
KGASETAILPGAAAIANAVYHAIGVRIHSLPITPEKVLAALREREEMEKESAHA
>Mature_774_residues
MQHKTQEAGMSESIVGASTPQVTAREKVMGRAQYAGDIKLPGMLHAKVLRSPHPHARIVSIDTAAAKALPGVKLVVTGRD
TPTRLWGPHRKEQRILAVGVVLHVGEEVAAVVAVSEEIARDALDLIRVAYEELPALLSPEAALADGAPEVHAGTRNIGHE
MHIERGDVEAGFAEAAAVYEATYDMHSQYPGYLEPMASVATQDGNGRLTVYASTQSVFLARSRLAEALDRPASTIRVVQA
TTGGGFGAKIVEENNSLICAFLATKLDRPVRMVNNRLEDFQGARASVPAKVWLRIGLSANGMIVAKDVRITAECGAYAGL
AGDVMHVSAMRSDNMHRVTNVRSHAVLAYTNNPPRGAFRGFGGQQMQFPLNCHLTVLAGMIGMDPIEVHKRNAIGRGETS
VHGWQIGSTGMQECLEMTRKAIGWDAKREAPRGTGTRRRGVGIAAAMHVSGNRTLGNWDGSTILLKLNEDGRVMLQTSEC
DMGQGANTMLSQICAQEMGIPLSHVTVMAPDTDTSPFCLGSLASRVTIISGNAVLRAAREAKQKVMALAAEKFGVDADSL
VFADGRISVPGQPDKSATLAEIARLHIFRHGGEGIHVRATYDAPTVMHDANYYGNIAPAYSFAAQAVEVEVDTCTGRVTV
IDSFVADDCGKAINPLAVHGQTHGATVQAIGWTLYEHLRYEDGRLQNGNFADYTMATADALPMLRTDLVESNDPNGPFGA
KGASETAILPGAAAIANAVYHAIGVRIHSLPITPEKVLAALREREEMEKESAHA

Specific function: Catalyzes reductive dehydroxylation of 4-hydroxybenzoyl- CoA. Reaction is not reversible [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To xanthine oxidases [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=781, Percent_Identity=26.7605633802817, Blast_Score=223, Evalue=7e-58,
Organism=Homo sapiens, GI71773480, Length=779, Percent_Identity=24.7753530166881, Blast_Score=171, Evalue=2e-42,
Organism=Escherichia coli, GI1789230, Length=756, Percent_Identity=32.5396825396825, Blast_Score=349, Evalue=3e-97,
Organism=Escherichia coli, GI1789246, Length=813, Percent_Identity=28.9052890528905, Blast_Score=284, Evalue=1e-77,
Organism=Escherichia coli, GI1786478, Length=763, Percent_Identity=28.0471821756225, Blast_Score=185, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17540638, Length=776, Percent_Identity=23.840206185567, Blast_Score=170, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17539860, Length=739, Percent_Identity=25.0338294993234, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI32566215, Length=733, Percent_Identity=23.1923601637108, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI17737937, Length=737, Percent_Identity=25.9158751696065, Blast_Score=189, Evalue=7e-48,
Organism=Drosophila melanogaster, GI24647193, Length=743, Percent_Identity=23.5531628532974, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24647201, Length=729, Percent_Identity=23.0452674897119, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017607
- InterPro:   IPR000674
- InterPro:   IPR008274 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.20 [H]

Molecular weight: Translated: 82701; Mature: 82701

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHKTQEAGMSESIVGASTPQVTAREKVMGRAQYAGDIKLPGMLHAKVLRSPHPHARIVS
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCEEEEE
IDTAAAKALPGVKLVVTGRDTPTRLWGPHRKEQRILAVGVVLHVGEEVAAVVAVSEEIAR
EEHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHHHH
DALDLIRVAYEELPALLSPEAALADGAPEVHAGTRNIGHEMHIERGDVEAGFAEAAAVYE
HHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHH
ATYDMHSQYPGYLEPMASVATQDGNGRLTVYASTQSVFLARSRLAEALDRPASTIRVVQA
HHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEE
TTGGGFGAKIVEENNSLICAFLATKLDRPVRMVNNRLEDFQGARASVPAKVWLRIGLSAN
ECCCCCCEEEEECCCCEEEEEEHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCC
GMIVAKDVRITAECGAYAGLAGDVMHVSAMRSDNMHRVTNVRSHAVLAYTNNPPRGAFRG
CEEEEECEEEEECCCCCCCCCCCHHEEHHHCCCCCHHHHCCCCCEEEEEECCCCCCHHCC
FGGQQMQFPLNCHLTVLAGMIGMDPIEVHKRNAIGRGETSVHGWQIGSTGMQECLEMTRK
CCCCEEEECCCCHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHH
AIGWDAKREAPRGTGTRRRGVGIAAAMHVSGNRTLGNWDGSTILLKLNEDGRVMLQTSEC
HHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEECCCCCCEEEEEECCCCEEEEEECCC
DMGQGANTMLSQICAQEMGIPLSHVTVMAPDTDTSPFCLGSLASRVTIISGNAVLRAARE
CCCCCHHHHHHHHHHHHHCCCCHHEEEECCCCCCCCHHHHHHHCEEEEEECCHHHHHHHH
AKQKVMALAAEKFGVDADSLVFADGRISVPGQPDKSATLAEIARLHIFRHGGEGIHVRAT
HHHHHHHHHHHHHCCCCCCEEEECCEEECCCCCCCCHHHHHHHHHHHEEECCCEEEEEEE
YDAPTVMHDANYYGNIAPAYSFAAQAVEVEVDTCTGRVTVIDSFVADDCGKAINPLAVHG
CCCCCEEECCCCCCCCCHHHHHHEEEEEEEEECCCCEEEEEHHHHHHHHCCCCCCEEEEC
QTHGATVQAIGWTLYEHLRYEDGRLQNGNFADYTMATADALPMLRTDLVESNDPNGPFGA
CCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCC
KGASETAILPGAAAIANAVYHAIGVRIHSLPITPEKVLAALREREEMEKESAHA
CCCCCCEECCCHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQHKTQEAGMSESIVGASTPQVTAREKVMGRAQYAGDIKLPGMLHAKVLRSPHPHARIVS
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCEEEEE
IDTAAAKALPGVKLVVTGRDTPTRLWGPHRKEQRILAVGVVLHVGEEVAAVVAVSEEIAR
EEHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHHHH
DALDLIRVAYEELPALLSPEAALADGAPEVHAGTRNIGHEMHIERGDVEAGFAEAAAVYE
HHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHH
ATYDMHSQYPGYLEPMASVATQDGNGRLTVYASTQSVFLARSRLAEALDRPASTIRVVQA
HHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEE
TTGGGFGAKIVEENNSLICAFLATKLDRPVRMVNNRLEDFQGARASVPAKVWLRIGLSAN
ECCCCCCEEEEECCCCEEEEEEHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCC
GMIVAKDVRITAECGAYAGLAGDVMHVSAMRSDNMHRVTNVRSHAVLAYTNNPPRGAFRG
CEEEEECEEEEECCCCCCCCCCCHHEEHHHCCCCCHHHHCCCCCEEEEEECCCCCCHHCC
FGGQQMQFPLNCHLTVLAGMIGMDPIEVHKRNAIGRGETSVHGWQIGSTGMQECLEMTRK
CCCCEEEECCCCHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHH
AIGWDAKREAPRGTGTRRRGVGIAAAMHVSGNRTLGNWDGSTILLKLNEDGRVMLQTSEC
HHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEECCCCCCEEEEEECCCCEEEEEECCC
DMGQGANTMLSQICAQEMGIPLSHVTVMAPDTDTSPFCLGSLASRVTIISGNAVLRAARE
CCCCCHHHHHHHHHHHHHCCCCHHEEEECCCCCCCCHHHHHHHCEEEEEECCHHHHHHHH
AKQKVMALAAEKFGVDADSLVFADGRISVPGQPDKSATLAEIARLHIFRHGGEGIHVRAT
HHHHHHHHHHHHHCCCCCCEEEECCEEECCCCCCCCHHHHHHHHHHHEEECCCEEEEEEE
YDAPTVMHDANYYGNIAPAYSFAAQAVEVEVDTCTGRVTVIDSFVADDCGKAINPLAVHG
CCCCCEEECCCCCCCCCHHHHHHEEEEEEEEECCCCEEEEEHHHHHHHHCCCCCCEEEEC
QTHGATVQAIGWTLYEHLRYEDGRLQNGNFADYTMATADALPMLRTDLVESNDPNGPFGA
CCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCC
KGASETAILPGAAAIANAVYHAIGVRIHSLPITPEKVLAALREREEMEKESAHA
CCCCCCEECCCHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9490068 [H]