Click here to switch to the map view.

The map label for this gene is frlR [H]

Identifier: 73537368

GI number: 73537368

Start: 79413

End: 80153

Strand: Direct

Name: frlR [H]

Synonym: Reut_B3533

Alternate gene names: 73537368

Gene position: 79413-80153 (Clockwise)

Preceding gene: 73537367

Following gene: 73537371

Centisome position: 2.91

GC content: 64.37

Gene sequence:

>741_bases
GTGGGCGCGAGATTCGAAGCGGGCAGCGCCATCGGCGGTGTCCTGTACAAGGATGTGAAGCAGGCGATACTCGCCGCGCT
GGCGGGCGGGGAATGGAAGCCGGGCGAGGTCATCCCGTCCGAACGCAAGCTGATCGAACGCTTCGGTGTGTCGATCGGCA
CGCTGCGCAAGGCGATCGACGAACTCGTGGCGGAGAACATCCTGATCCGCCATCAGGGCCGCGGCACGTTCGTGGCGACG
CATCGGCTCGAAGACCATTTCTTCCGCTTCTTCCGCATCGTCCGGCAGGACGGGCATCGCGAATATCCGACCGTGCAGCT
GGCCAGGTTCCGCCGGGCCAAGGCAGACAAGGACGAGGCGGCCGCACTGGGGCTGGCGGTCGGCGAGCCCGTGTTCCGGT
TCACCAACGTCCTGTCGCTGGAAGGCAAGCCGGTCATGATCGACGCCATCACGGTCCCAGAGGAACGGTTTAAAGCGCTG
TCCGAGAAGCAACTGCGCGAGCGTCCCAATACGCTCTACAACTTCTACCAGGATGCGTTCGGCATCAACATCATCCGCAC
CGAGGAACGCCTGCGTTCGGCGCTCGCCGACGAGGATGACGAGGCATTGCTCGGCGTGCCGGTCGGCAGCCCGCTGCTGA
AGATCCTGCGAGTCGCATCGTCGTATCACGACGAGCGCATCGAATATCGCGTGTCGCGGCTCGATACCACCGGCCACGAG
TTCGTGCTGTCGCAGCCCTGA

Upstream 100 bases:

>100_bases
GCATGGGGTTCGCGCCGGTGACAGGCATGGCGCGGCGGCAGGAAATTGCTTTGATATGATCCGGCCTATCTAAGGAATTG
CATCTCAGGGGATCCTCAAC

Downstream 100 bases:

>100_bases
GACGCTGAGCCCTGAATCCTGAATCCTGAAGCTGAAACGCAGCGCGGCGAACGCGAACCGGACTAGGTCCGGCTCAGGTT
CGCCGCGCTGGACGACGCTC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MGARFEAGSAIGGVLYKDVKQAILAALAGGEWKPGEVIPSERKLIERFGVSIGTLRKAIDELVAENILIRHQGRGTFVAT
HRLEDHFFRFFRIVRQDGHREYPTVQLARFRRAKADKDEAAALGLAVGEPVFRFTNVLSLEGKPVMIDAITVPEERFKAL
SEKQLRERPNTLYNFYQDAFGINIIRTEERLRSALADEDDEALLGVPVGSPLLKILRVASSYHDERIEYRVSRLDTTGHE
FVLSQP

Sequences:

>Translated_246_residues
MGARFEAGSAIGGVLYKDVKQAILAALAGGEWKPGEVIPSERKLIERFGVSIGTLRKAIDELVAENILIRHQGRGTFVAT
HRLEDHFFRFFRIVRQDGHREYPTVQLARFRRAKADKDEAAALGLAVGEPVFRFTNVLSLEGKPVMIDAITVPEERFKAL
SEKQLRERPNTLYNFYQDAFGINIIRTEERLRSALADEDDEALLGVPVGSPLLKILRVASSYHDERIEYRVSRLDTTGHE
FVLSQP
>Mature_245_residues
GARFEAGSAIGGVLYKDVKQAILAALAGGEWKPGEVIPSERKLIERFGVSIGTLRKAIDELVAENILIRHQGRGTFVATH
RLEDHFFRFFRIVRQDGHREYPTVQLARFRRAKADKDEAAALGLAVGEPVFRFTNVLSLEGKPVMIDAITVPEERFKALS
EKQLRERPNTLYNFYQDAFGINIIRTEERLRSALADEDDEALLGVPVGSPLLKILRVASSYHDERIEYRVSRLDTTGHEF
VLSQP

Specific function: May regulate the transcription of the frlABCD operon [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082252, Length=237, Percent_Identity=25.7383966244726, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790118, Length=222, Percent_Identity=27.4774774774775, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786950, Length=232, Percent_Identity=27.1551724137931, Blast_Score=74, Evalue=9e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27731; Mature: 27600

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGARFEAGSAIGGVLYKDVKQAILAALAGGEWKPGEVIPSERKLIERFGVSIGTLRKAID
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHH
ELVAENILIRHQGRGTFVATHRLEDHFFRFFRIVRQDGHREYPTVQLARFRRAKADKDEA
HHHHHHHEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHH
AALGLAVGEPVFRFTNVLSLEGKPVMIDAITVPEERFKALSEKQLRERPNTLYNFYQDAF
HHHHHHHCCHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHH
GINIIRTEERLRSALADEDDEALLGVPVGSPLLKILRVASSYHDERIEYRVSRLDTTGHE
CCEEEEHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FVLSQP
EEECCC
>Mature Secondary Structure 
GARFEAGSAIGGVLYKDVKQAILAALAGGEWKPGEVIPSERKLIERFGVSIGTLRKAID
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHH
ELVAENILIRHQGRGTFVATHRLEDHFFRFFRIVRQDGHREYPTVQLARFRRAKADKDEA
HHHHHHHEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHH
AALGLAVGEPVFRFTNVLSLEGKPVMIDAITVPEERFKALSEKQLRERPNTLYNFYQDAF
HHHHHHHCCHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHH
GINIIRTEERLRSALADEDDEALLGVPVGSPLLKILRVASSYHDERIEYRVSRLDTTGHE
CCEEEEHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FVLSQP
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]