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The map label for this gene is pncA [H]

Identifier: 71911324

GI number: 71911324

Start: 1464245

End: 1464691

Strand: Reverse

Name: pncA [H]

Synonym: M5005_Spy_1511

Alternate gene names: 71911324

Gene position: 1464691-1464245 (Counterclockwise)

Preceding gene: 71911325

Following gene: 71911323

Centisome position: 79.67

GC content: 35.12

Gene sequence:

>447_bases
ATGAGAGCATTGATTTCAATTGATTACACAAATGATTTTGTAGCAGATGATGGTAAATTAAGTGCAGGTAAATCTGCTCA
GGCTATTGCCACTAAAATAGCAGAGGTAACTAAAACGGCATTTGATCAAGGAGACTATATTTTTTTTGCTATTGATTGTC
ATGATCAAAATGATTCTTGGCATCCTGAGAGTAAGCTATTTGCAGCACATAATATCAAAGGAACTACTGGACGCCATCTT
TATGGTCCACTAGCTGAAGTTTACAGTTATATGAAGCAACATCCCAGAGTTTTTTGGATTGATAAGCGTTATTATTCAGC
TTTTTCGGGGACTGATTTAGATATTAGACTACGAGAAAGAGGTATCACTCAATTAGTGTTAACAGGAGTTTTATCTGATA
TCTGTGTCTTACATACTGCTATTGACGCTTATCATCTTGGTTATTAA

Upstream 100 bases:

>100_bases
ATGGTAGATGCAAATAGATGTCTTGATACCTGTAATAAAAACTGATACAATGCCATATATAAGAGATAAGGGGAGAGGTT
TCCCTGTTTAGGAGATAGTG

Downstream 100 bases:

>100_bases
TTAGAGATTGTTAAATCGGCTGTCGCTAGCCTTACAAAAGAATCTTATGAGTGGTCTTTGGCTCACTTTGAGCAGGTTCT
TGGTGCTAAGCTTATTAACG

Product: pyrazinamidase/nicotinamidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQGDYIFFAIDCHDQNDSWHPESKLFAAHNIKGTTGRHL
YGPLAEVYSYMKQHPRVFWIDKRYYSAFSGTDLDIRLRERGITQLVLTGVLSDICVLHTAIDAYHLGY

Sequences:

>Translated_148_residues
MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQGDYIFFAIDCHDQNDSWHPESKLFAAHNIKGTTGRHL
YGPLAEVYSYMKQHPRVFWIDKRYYSAFSGTDLDIRLRERGITQLVLTGVLSDICVLHTAIDAYHLGY
>Mature_148_residues
MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQGDYIFFAIDCHDQNDSWHPESKLFAAHNIKGTTGRHL
YGPLAEVYSYMKQHPRVFWIDKRYYSAFSGTDLDIRLRERGITQLVLTGVLSDICVLHTAIDAYHLGY

Specific function: Unknown

COG id: COG1335

COG function: function code Q; Amidases related to nicotinamidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismatase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000868 [H]

Pfam domain/function: PF00857 Isochorismatase [H]

EC number: 3.5.1.-; 3.5.1.19

Molecular weight: Translated: 16680; Mature: 16680

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQGDYIFFAIDCHDQNDSW
CCEEEEEECCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCC
HPESKLFAAHNIKGTTGRHLYGPLAEVYSYMKQHPRVFWIDKRYYSAFSGTDLDIRLRER
CCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEHHHHHHCCCCCEEEEECCC
GITQLVLTGVLSDICVLHTAIDAYHLGY
CHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQGDYIFFAIDCHDQNDSW
CCEEEEEECCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCC
HPESKLFAAHNIKGTTGRHLYGPLAEVYSYMKQHPRVFWIDKRYYSAFSGTDLDIRLRER
CCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEHHHHHHCCCCCEEEEECCC
GITQLVLTGVLSDICVLHTAIDAYHLGY
CHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]