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The map label for this gene is comFA [H]

Identifier: 71911140

GI number: 71911140

Start: 1293295

End: 1294509

Strand: Reverse

Name: comFA [H]

Synonym: M5005_Spy_1327

Alternate gene names: 71911140

Gene position: 1294509-1293295 (Counterclockwise)

Preceding gene: 71911143

Following gene: 71911139

Centisome position: 70.41

GC content: 36.3

Gene sequence:

>1215_bases
ATGATTTGTCAACGTTGTCACTATCAGCTTGATGAAGAAGCACGATTGCCAAGTGGAGCCTATTATTGCCGATTTTGTCT
TGTCTTTGGACGAAATCAATCAGATAAATTGCTCTATGCTATCCCACCTATGCATTTTCCAAAAGGTAATTATCTGGTTT
GGGGCGGTCAACTAACTGCTTATCAAGAGATGATTTCCCAACAATTATTAATCAATATGCAAAATCAAAAAACAACATTA
GTTCATGCTGTAACTGGTGCAGGAAAAACAGAAATGATTTATGCTGCGATTGAGGCGGTAATTAACACAGGTGGCTGGGT
TTGCATTGCCAGCCCAAGAGTAGATGTTTGTGTAGAGGTGGCTACTCGTTTATCCCAAGCCTTCTCCTGCAGCATCTGTT
TAATGCACGCAGAGTCTCTTCCTTATCAAAGAGCTCCTATTATAGTAGCCACAACGCATCAGCTGCTAAAATTTCACAAG
GCTTTTGATCTCTTAATTATTGATGAAGTAGACGCATTCCCTTTTGTAAATAATATTCAACTTCATTATGCTGCAAGTCA
GGCTTTAAAAGAAGGTGGCGCAAAGATTTTATTAACTGCAACTTCAACTAGAACTTTAGAAAGAAAGGTAAACAAGGGAG
AAGTAGTCAAGCTGACATTGGCGAGACGCTTTCATAATAGGCCATTAGTTATTCCAAAATTTATAAGAAGTTTTAATCTA
TTTAAAATGATACATCGGCAAAAACTTCCTCTTAAAATTTTAAAATACTTAAAAAAACAAAGAAAAACAGGCTATCCCCT
TTTAATTTTTCTACCCACTATTATAATGGCAGAATCTGTTACAGCAATCTTAAAAGAGTTATTGCCCGCCGAACAAATAG
CTTGTGTTTCTAGTCAATCACAAAACAGGAAAGAAGATATCACAGCTTTTCGTCAAGGGAAAAAAACGATTTTAATTACA
ACATCAATTTTAGAAAGGGGTGTGACATTTCCCCAAATTGATGTTTTTGTTCTTGGGTCTCATCATCGTGTCTATAGTTC
CCAAAGTCTTGTTCAAATTGCTGGACGAGTTGGAAGATCTATAGACAGACCAGACGGAACGTTATATTTCTTTCATGAAG
GTATCAGTAAAGCAATGCTACTAGCAAGAAAAGAGATTAAAGAAATGAATTATAAAGGGTATTCGCATGATCTGTCTACT
ATGTCAACAAATTAG

Upstream 100 bases:

>100_bases
TGAAAATAGTTATGGACGGTTGTTGCTAGAAAGCCAGTTACCAGATTCAGCAAAGCAGCTTGCTCAACCTTTAAAAAGTG
TAGTAATATTGAGAGGAAAA

Downstream 100 bases:

>100_bases
TCAAACACCAATAAGTATTACAGAAATCATCTTTTTAAGACGTATCTCTTCACCGATTTGTCAACAATGTCAAAAAAGCT
TTCAAAAGATAGGAAAAAGT

Product: COMF operon protein 1

Products: NA

Alternate protein names: ATP-dependent helicase ComFA [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MICQRCHYQLDEEARLPSGAYYCRFCLVFGRNQSDKLLYAIPPMHFPKGNYLVWGGQLTAYQEMISQQLLINMQNQKTTL
VHAVTGAGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEVATRLSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHK
AFDLLIIDEVDAFPFVNNIQLHYAASQALKEGGAKILLTATSTRTLERKVNKGEVVKLTLARRFHNRPLVIPKFIRSFNL
FKMIHRQKLPLKILKYLKKQRKTGYPLLIFLPTIIMAESVTAILKELLPAEQIACVSSQSQNRKEDITAFRQGKKTILIT
TSILERGVTFPQIDVFVLGSHHRVYSSQSLVQIAGRVGRSIDRPDGTLYFFHEGISKAMLLARKEIKEMNYKGYSHDLST
MSTN

Sequences:

>Translated_404_residues
MICQRCHYQLDEEARLPSGAYYCRFCLVFGRNQSDKLLYAIPPMHFPKGNYLVWGGQLTAYQEMISQQLLINMQNQKTTL
VHAVTGAGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEVATRLSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHK
AFDLLIIDEVDAFPFVNNIQLHYAASQALKEGGAKILLTATSTRTLERKVNKGEVVKLTLARRFHNRPLVIPKFIRSFNL
FKMIHRQKLPLKILKYLKKQRKTGYPLLIFLPTIIMAESVTAILKELLPAEQIACVSSQSQNRKEDITAFRQGKKTILIT
TSILERGVTFPQIDVFVLGSHHRVYSSQSLVQIAGRVGRSIDRPDGTLYFFHEGISKAMLLARKEIKEMNYKGYSHDLST
MSTN
>Mature_404_residues
MICQRCHYQLDEEARLPSGAYYCRFCLVFGRNQSDKLLYAIPPMHFPKGNYLVWGGQLTAYQEMISQQLLINMQNQKTTL
VHAVTGAGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEVATRLSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHK
AFDLLIIDEVDAFPFVNNIQLHYAASQALKEGGAKILLTATSTRTLERKVNKGEVVKLTLARRFHNRPLVIPKFIRSFNL
FKMIHRQKLPLKILKYLKKQRKTGYPLLIFLPTIIMAESVTAILKELLPAEQIACVSSQSQNRKEDITAFRQGKKTILIT
TSILERGVTFPQIDVFVLGSHHRVYSSQSLVQIAGRVGRSIDRPDGTLYFFHEGISKAMLLARKEIKEMNYKGYSHDLST
MSTN

Specific function: Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel [H]

COG id: COG4098

COG function: function code L; Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 45696; Mature: 45696

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICQRCHYQLDEEARLPSGAYYCRFCLVFGRNQSDKLLYAIPPMHFPKGNYLVWGGQLTA
CCCCHHCCCCCCCCCCCCCHHHEEEEEEECCCCCCCEEEEECCCCCCCCCEEEECCCHHH
YQEMISQQLLINMQNQKTTLVHAVTGAGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEV
HHHHHHHHHHEECCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHH
ATRLSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHKAFDLLIIDEVDAFPFVNNIQ
HHHHHHHHHHEEEEEECCCCCCCCCCEEEECHHHHHHHHHHHCEEEEECCCCCCCCCCEE
LHYAASQALKEGGAKILLTATSTRTLERKVNKGEVVKLTLARRFHNRPLVIPKFIRSFNL
EEEHHHHHHHHCCCEEEEEECCCHHHHHHCCCCCEEEEEEHHHHCCCCEEHHHHHHHHHH
FKMIHRQKLPLKILKYLKKQRKTGYPLLIFLPTIIMAESVTAILKELLPAEQIACVSSQS
HHHHHHCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCC
QNRKEDITAFRQGKKTILITTSILERGVTFPQIDVFVLGSHHRVYSSQSLVQIAGRVGRS
CCHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCEEEEEECCCCEECCCHHHHHHHHHHCCC
IDRPDGTLYFFHEGISKAMLLARKEIKEMNYKGYSHDLSTMSTN
CCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MICQRCHYQLDEEARLPSGAYYCRFCLVFGRNQSDKLLYAIPPMHFPKGNYLVWGGQLTA
CCCCHHCCCCCCCCCCCCCHHHEEEEEEECCCCCCCEEEEECCCCCCCCCEEEECCCHHH
YQEMISQQLLINMQNQKTTLVHAVTGAGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEV
HHHHHHHHHHEECCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHH
ATRLSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHKAFDLLIIDEVDAFPFVNNIQ
HHHHHHHHHHEEEEEECCCCCCCCCCEEEECHHHHHHHHHHHCEEEEECCCCCCCCCCEE
LHYAASQALKEGGAKILLTATSTRTLERKVNKGEVVKLTLARRFHNRPLVIPKFIRSFNL
EEEHHHHHHHHCCCEEEEEECCCHHHHHHCCCCCEEEEEEHHHHCCCCEEHHHHHHHHHH
FKMIHRQKLPLKILKYLKKQRKTGYPLLIFLPTIIMAESVTAILKELLPAEQIACVSSQS
HHHHHHCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCC
QNRKEDITAFRQGKKTILITTSILERGVTFPQIDVFVLGSHHRVYSSQSLVQIAGRVGRS
CCHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCEEEEEECCCCEECCCHHHHHHHHHHCCC
IDRPDGTLYFFHEGISKAMLLARKEIKEMNYKGYSHDLSTMSTN
CCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8412657; 9384377 [H]