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The map label for this gene is zosA [H]

Identifier: 71910980

GI number: 71910980

Start: 1143271

End: 1145133

Strand: Reverse

Name: zosA [H]

Synonym: M5005_Spy_1167

Alternate gene names: 71910980

Gene position: 1145133-1143271 (Counterclockwise)

Preceding gene: 71910981

Following gene: 71910979

Centisome position: 62.28

GC content: 40.53

Gene sequence:

>1863_bases
ATGACAATCAGACAATGGATGGCAGACCATCTTCATTTGATGGAGACTTTAGCGTGTTTGGTATTAATAATAATTGGCCT
AGCCTTTTTACACTCATTTCCACAAGTGGCTTCCGCTATTTTCATTACAGCCTTCTTGATTGGAGGATATGCGTCTGCAA
AAACGGGTATATTGGATTTGGTGAAGAACAAACACTTGTCAGTGGATATTTTGATGATTTTGGCAGCTATCGGTGCTGGA
ATTATCGGCTATTGGCTGGAGGGTGCTCTGCTTATTTTTATCTTTTCGTTGTCCAATACGCTTGAAGAAATGGCCATGGA
AAAAAGTAAGGATGCTATTTCAGCCTTGATGTCCTTGACGCCAGATACAGCTCGTCAATACCAAGAAGATGGCCATATTT
TAGAAGTTGAGACCAGATCCTTGAGTGTTGGTGACCGTTTACAAGTTCGTAAAGGCGAAGCTGTTCCAATTGACGGGCAG
TTGCTTAGTCCTTTTGGTCAATTTGATGAATCTATGGTCACTGGTGAGCCTATCACTGTTGATAAGGCAGAAGGCCAGGA
TCTGATTGGGGGAACCATTAACCAAGGACAAACCATAGATATGTTGGTTACTATTGAAAATGACGATACTCTCTTTGCCA
AGATTATTAATCTGGTGGAATCTGCCCAAGAAAAGAAAAGCAAAACCGCCACCTTTATCGAAAGCTTAGAAGATGGTTAT
GTCAAATTTGTGCTCGTCCTTATTCCTGCCTTTATCCTCTTTAGCCACTTTGTGCTTTCTTGGACTTGGTTGGCTGCTTT
TTACCGAGGGATGATTCTCTTAACAGTAGCTTCACCATGTGCCCTAATTGCCAGTTCCACACCTGCTAGCTTGGCTGCTA
TTTCTCGTGCAGCCAGAAAGGGATTGATTATCAAAGGAGGGGATATTGTCGATAACATGGGAGATATTAAGGCTGTTGTC
ATGGATAAAACGGGAACGCTCACCCAAGGAAAACCTTCTGTTGTGAATGCTCATTATTTGGAAGATGAGTTGCTCGTGAA
TAGACTGGTAAAAGGAGCAGAGACTGCTAGTACCCATCCTATTTCTAAAGCCCTTCTTGAATACACTGAAAAATTGGAGC
CACTGACCTTTGACCACTTAGAAGAAATTTCTGGGAAAGGTTTTCAGGGCTTCTATCAAGGGCAAGAATGGCGAATTGGC
AAGAAAACCTACATTTTGGAAAAGGTTCAAGACCTATCAGCTTTTGAAGAAACTATTCAAGTGGAAGAAAAACAAGGGAA
AACCCTAATCTTTGTTTCACGTGACCATCAATTGATAGCTTACTATGCCCTCTTGGATGATATCAAAATAGAATCAAAAC
GTGCTATTAAGTCTCTTCATGCCATGGGAATCAAAACAGTCATGTTAACAGGTGACCAAGAACGAACCGCCAATTATGTG
GCACAAAAACTTGGTATTGATGAAGTGGTAGCCAACTGTATGCCTCAAGATAAGGTGGCTAAGTTAGCAGAATTAAAGAC
TAAATATGGTTTTGTGGCTATGGTAGGAGATGGTATTAATGATGCTCCTGCCCTTGCTCAAGCAGATGTTTCTTATGCTA
TTGGATCAGGAACAGATATTGCAATGGAAAGTGCAGACAGTGTGATTATGGATGACTTGACTCGTATTCCATTTTCGATT
CAACTTTCCCGCACAATGAAGACCATTATCAAACAAAATATTGTTTTTGCCTTATCTGTGATTACCTTATTGATTTTAGC
CAATGTTTTTCAGGTAGTTAACTTGCCGCTTGGTGTTGTTGGACACGAAGGCTCAACGATTTTAGTGATTTTAAATGGCT
TGCGTTTACTTTCTTTTAAATAA

Upstream 100 bases:

>100_bases
TATTTAGAATGTTTCTAAATTACTTGACTTATTTATTTAGAATTATTATAATTAATATATCTTAAAGATTGAATAACTTT
TAATTGCGAGGGAACTAAAA

Downstream 100 bases:

>100_bases
TTTAGAAACTTGCTTGAAAACTTGAAAGTGTTTATAATAATAGTAAGACTTATGAAAGAGAAAACCGCCGTATGTTTACT
ATTATGATCATTGGTTTAGC

Product: lead, cadmium, zinc and mercury transporting ATPase

Products: NA

Alternate protein names: Zn(2+)-translocating P-type ATPase [H]

Number of amino acids: Translated: 620; Mature: 619

Protein sequence:

>620_residues
MTIRQWMADHLHLMETLACLVLIIIGLAFLHSFPQVASAIFITAFLIGGYASAKTGILDLVKNKHLSVDILMILAAIGAG
IIGYWLEGALLIFIFSLSNTLEEMAMEKSKDAISALMSLTPDTARQYQEDGHILEVETRSLSVGDRLQVRKGEAVPIDGQ
LLSPFGQFDESMVTGEPITVDKAEGQDLIGGTINQGQTIDMLVTIENDDTLFAKIINLVESAQEKKSKTATFIESLEDGY
VKFVLVLIPAFILFSHFVLSWTWLAAFYRGMILLTVASPCALIASSTPASLAAISRAARKGLIIKGGDIVDNMGDIKAVV
MDKTGTLTQGKPSVVNAHYLEDELLVNRLVKGAETASTHPISKALLEYTEKLEPLTFDHLEEISGKGFQGFYQGQEWRIG
KKTYILEKVQDLSAFEETIQVEEKQGKTLIFVSRDHQLIAYYALLDDIKIESKRAIKSLHAMGIKTVMLTGDQERTANYV
AQKLGIDEVVANCMPQDKVAKLAELKTKYGFVAMVGDGINDAPALAQADVSYAIGSGTDIAMESADSVIMDDLTRIPFSI
QLSRTMKTIIKQNIVFALSVITLLILANVFQVVNLPLGVVGHEGSTILVILNGLRLLSFK

Sequences:

>Translated_620_residues
MTIRQWMADHLHLMETLACLVLIIIGLAFLHSFPQVASAIFITAFLIGGYASAKTGILDLVKNKHLSVDILMILAAIGAG
IIGYWLEGALLIFIFSLSNTLEEMAMEKSKDAISALMSLTPDTARQYQEDGHILEVETRSLSVGDRLQVRKGEAVPIDGQ
LLSPFGQFDESMVTGEPITVDKAEGQDLIGGTINQGQTIDMLVTIENDDTLFAKIINLVESAQEKKSKTATFIESLEDGY
VKFVLVLIPAFILFSHFVLSWTWLAAFYRGMILLTVASPCALIASSTPASLAAISRAARKGLIIKGGDIVDNMGDIKAVV
MDKTGTLTQGKPSVVNAHYLEDELLVNRLVKGAETASTHPISKALLEYTEKLEPLTFDHLEEISGKGFQGFYQGQEWRIG
KKTYILEKVQDLSAFEETIQVEEKQGKTLIFVSRDHQLIAYYALLDDIKIESKRAIKSLHAMGIKTVMLTGDQERTANYV
AQKLGIDEVVANCMPQDKVAKLAELKTKYGFVAMVGDGINDAPALAQADVSYAIGSGTDIAMESADSVIMDDLTRIPFSI
QLSRTMKTIIKQNIVFALSVITLLILANVFQVVNLPLGVVGHEGSTILVILNGLRLLSFK
>Mature_619_residues
TIRQWMADHLHLMETLACLVLIIIGLAFLHSFPQVASAIFITAFLIGGYASAKTGILDLVKNKHLSVDILMILAAIGAGI
IGYWLEGALLIFIFSLSNTLEEMAMEKSKDAISALMSLTPDTARQYQEDGHILEVETRSLSVGDRLQVRKGEAVPIDGQL
LSPFGQFDESMVTGEPITVDKAEGQDLIGGTINQGQTIDMLVTIENDDTLFAKIINLVESAQEKKSKTATFIESLEDGYV
KFVLVLIPAFILFSHFVLSWTWLAAFYRGMILLTVASPCALIASSTPASLAAISRAARKGLIIKGGDIVDNMGDIKAVVM
DKTGTLTQGKPSVVNAHYLEDELLVNRLVKGAETASTHPISKALLEYTEKLEPLTFDHLEEISGKGFQGFYQGQEWRIGK
KTYILEKVQDLSAFEETIQVEEKQGKTLIFVSRDHQLIAYYALLDDIKIESKRAIKSLHAMGIKTVMLTGDQERTANYVA
QKLGIDEVVANCMPQDKVAKLAELKTKYGFVAMVGDGINDAPALAQADVSYAIGSGTDIAMESADSVIMDDLTRIPFSIQ
LSRTMKTIIKQNIVFALSVITLLILANVFQVVNLPLGVVGHEGSTILVILNGLRLLSFK

Specific function: Couples the hydrolysis of ATP with the transport of zinc into the cell [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=585, Percent_Identity=31.7948717948718, Blast_Score=238, Evalue=2e-62,
Organism=Homo sapiens, GI115529486, Length=602, Percent_Identity=30.2325581395349, Blast_Score=223, Evalue=6e-58,
Organism=Homo sapiens, GI55743073, Length=546, Percent_Identity=31.8681318681319, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI51944966, Length=310, Percent_Identity=26.4516129032258, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI209413709, Length=234, Percent_Identity=26.9230769230769, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI24638454, Length=234, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4502285, Length=234, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI22748667, Length=245, Percent_Identity=27.3469387755102, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI48762689, Length=184, Percent_Identity=29.8913043478261, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI48762687, Length=184, Percent_Identity=29.8913043478261, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI48762691, Length=184, Percent_Identity=29.8913043478261, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI48762685, Length=184, Percent_Identity=29.8913043478261, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI4502271, Length=311, Percent_Identity=24.7588424437299, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI237681111, Length=249, Percent_Identity=26.1044176706827, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI237681109, Length=249, Percent_Identity=26.1044176706827, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI21361181, Length=249, Percent_Identity=26.1044176706827, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI1789879, Length=625, Percent_Identity=33.92, Blast_Score=314, Evalue=1e-86,
Organism=Escherichia coli, GI1786691, Length=550, Percent_Identity=32.1818181818182, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI1786914, Length=494, Percent_Identity=26.3157894736842, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI2367363, Length=585, Percent_Identity=25.2991452991453, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17556548, Length=177, Percent_Identity=38.9830508474576, Blast_Score=116, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17559224, Length=271, Percent_Identity=26.9372693726937, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320475, Length=561, Percent_Identity=30.3030303030303, Blast_Score=199, Evalue=9e-52,
Organism=Saccharomyces cerevisiae, GI6319772, Length=608, Percent_Identity=23.8486842105263, Blast_Score=134, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6321430, Length=528, Percent_Identity=24.4318181818182, Blast_Score=118, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6325221, Length=590, Percent_Identity=23.2203389830508, Blast_Score=114, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6320243, Length=197, Percent_Identity=30.9644670050761, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6320244, Length=197, Percent_Identity=30.9644670050761, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6320245, Length=197, Percent_Identity=30.4568527918782, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321271, Length=202, Percent_Identity=28.7128712871287, Blast_Score=74, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6321432, Length=182, Percent_Identity=31.8681318681319, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI221329854, Length=190, Percent_Identity=38.4210526315789, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI281366617, Length=220, Percent_Identity=26.8181818181818, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24668696, Length=220, Percent_Identity=26.8181818181818, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24668708, Length=220, Percent_Identity=26.8181818181818, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24668704, Length=220, Percent_Identity=26.8181818181818, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI161085803, Length=220, Percent_Identity=26.8181818181818, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR001366
- InterPro:   IPR006404
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR000150 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: =3.6.3.5 [H]

Molecular weight: Translated: 67720; Mature: 67589

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00154 ATPASE_E1_E2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRQWMADHLHLMETLACLVLIIIGLAFLHSFPQVASAIFITAFLIGGYASAKTGILDL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VKNKHLSVDILMILAAIGAGIIGYWLEGALLIFIFSLSNTLEEMAMEKSKDAISALMSLT
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDTARQYQEDGHILEVETRSLSVGDRLQVRKGEAVPIDGQLLSPFGQFDESMVTGEPITV
CHHHHHHHCCCCEEEEEECCCCCCCCEEECCCCCCCCCCHHHCCHHHHCCCCCCCCCEEE
DKAEGQDLIGGTINQGQTIDMLVTIENDDTLFAKIINLVESAQEKKSKTATFIESLEDGY
ECCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKFVLVLIPAFILFSHFVLSWTWLAAFYRGMILLTVASPCALIASSTPASLAAISRAARK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHCCHHHHCCCCCHHHHHHHHHHHC
GLIIKGGDIVDNMGDIKAVVMDKTGTLTQGKPSVVNAHYLEDELLVNRLVKGAETASTHP
CEEEECCCHHCCCCCEEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCH
ISKALLEYTEKLEPLTFDHLEEISGKGFQGFYQGQEWRIGKKTYILEKVQDLSAFEETIQ
HHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHH
VEEKQGKTLIFVSRDHQLIAYYALLDDIKIESKRAIKSLHAMGIKTVMLTGDQERTANYV
HHHCCCCEEEEEECCCCEEEHHHHHHHHCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHH
AQKLGIDEVVANCMPQDKVAKLAELKTKYGFVAMVGDGINDAPALAQADVSYAIGSGTDI
HHHCCHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHCCCCEECCCCCCH
AMESADSVIMDDLTRIPFSIQLSRTMKTIIKQNIVFALSVITLLILANVFQVVNLPLGVV
HHHCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
GHEGSTILVILNGLRLLSFK
CCCCCEEEEEEECCCHHCCC
>Mature Secondary Structure 
TIRQWMADHLHLMETLACLVLIIIGLAFLHSFPQVASAIFITAFLIGGYASAKTGILDL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VKNKHLSVDILMILAAIGAGIIGYWLEGALLIFIFSLSNTLEEMAMEKSKDAISALMSLT
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDTARQYQEDGHILEVETRSLSVGDRLQVRKGEAVPIDGQLLSPFGQFDESMVTGEPITV
CHHHHHHHCCCCEEEEEECCCCCCCCEEECCCCCCCCCCHHHCCHHHHCCCCCCCCCEEE
DKAEGQDLIGGTINQGQTIDMLVTIENDDTLFAKIINLVESAQEKKSKTATFIESLEDGY
ECCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKFVLVLIPAFILFSHFVLSWTWLAAFYRGMILLTVASPCALIASSTPASLAAISRAARK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHCCHHHHCCCCCHHHHHHHHHHHC
GLIIKGGDIVDNMGDIKAVVMDKTGTLTQGKPSVVNAHYLEDELLVNRLVKGAETASTHP
CEEEECCCHHCCCCCEEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCH
ISKALLEYTEKLEPLTFDHLEEISGKGFQGFYQGQEWRIGKKTYILEKVQDLSAFEETIQ
HHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHH
VEEKQGKTLIFVSRDHQLIAYYALLDDIKIESKRAIKSLHAMGIKTVMLTGDQERTANYV
HHHCCCCEEEEEECCCCEEEHHHHHHHHCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHH
AQKLGIDEVVANCMPQDKVAKLAELKTKYGFVAMVGDGINDAPALAQADVSYAIGSGTDI
HHHCCHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHCCCCEECCCCCCH
AMESADSVIMDDLTRIPFSIQLSRTMKTIIKQNIVFALSVITLLILANVFQVVNLPLGVV
HHHCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
GHEGSTILVILNGLRLLSFK
CCCCCEEEEEEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]