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The map label for this gene is gpmA [H]

Identifier: 71910977

GI number: 71910977

Start: 1141102

End: 1141797

Strand: Reverse

Name: gpmA [H]

Synonym: M5005_Spy_1164

Alternate gene names: 71910977

Gene position: 1141797-1141102 (Counterclockwise)

Preceding gene: 71910979

Following gene: 71910976

Centisome position: 62.1

GC content: 41.81

Gene sequence:

>696_bases
ATGGTAAAATTGGTTTTCGCTCGCCACGGTGAGTCAGAATGGAACAAAGCTAACCTCTTCACTGGTTGGGCAGATGTTGA
TCTTTCAGAAAAAGGGACACAACAAGCGATTGATGCAGGTAAATTGATCAAAGAAGCAGGTATTGAATTTGACCTTGCTT
TCACTTCAGTATTGACACGTGCTATCAAAACAACTAACCTTGCCCTTGAAAATGCAGGTCAATTGTGGGTTCCAACTGAA
AAATCATGGCGCTTGAACGAGCGTCACTATGGTGCTTTGACTGGCAAAAACAAAGCTGAAGCTGCAGAACAATTTGGTGA
TGAACAAGTTCATATCTGGCGTCGTTCATACGACGTGTTGCCGCCAGCTATGGCTAAAGATGATGAGTATTCAGCACACA
AAGACCGTCGTTATGCTGATCTTGACCCAGCCCTTATTCCAGATGCTGAAAACTTAAAAGTAACTCTTGAACGCGCAATG
CCTTACTGGGAAGAAAAAATTGCTCCAGCTCTTCTTGACGGTAAAAACGTCTTTGTTGGCGCACATGGTAACTCAATCCG
CGCTCTTGTGAAACACATTAAAGGTCTTTCAGATGACGAAATCATGGATGTGGAAATTCCAAACTTCCCACCACTTGTTT
TTGAATTAGATGAAAAACTTAACATTGTTAAAGAATACTACCTTGGTGGTGAATAA

Upstream 100 bases:

>100_bases
TTCAATAAAGTCAGAATAGACTAGCTTTTTTGCTATATTTTTTGTAAAATAGGAACTGTAAAAAGGTAGCAACCTTTAAA
TTAAAAGGAGATATTAACTC

Downstream 100 bases:

>100_bases
CTTAAAAACCAGACTTTGGTCTGGTTTTTTGGTTCTATATCCTAAGAAGAAAGAAAACCCTGCTTAAAAATATGATATGA
TAGAAATAAAAAAGGATAGA

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEFDLAFTSVLTRAIKTTNLALENAGQLWVPTE
KSWRLNERHYGALTGKNKAEAAEQFGDEQVHIWRRSYDVLPPAMAKDDEYSAHKDRRYADLDPALIPDAENLKVTLERAM
PYWEEKIAPALLDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFELDEKLNIVKEYYLGGE

Sequences:

>Translated_231_residues
MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEFDLAFTSVLTRAIKTTNLALENAGQLWVPTE
KSWRLNERHYGALTGKNKAEAAEQFGDEQVHIWRRSYDVLPPAMAKDDEYSAHKDRRYADLDPALIPDAENLKVTLERAM
PYWEEKIAPALLDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFELDEKLNIVKEYYLGGE
>Mature_231_residues
MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEFDLAFTSVLTRAIKTTNLALENAGQLWVPTE
KSWRLNERHYGALTGKNKAEAAEQFGDEQVHIWRRSYDVLPPAMAKDDEYSAHKDRRYADLDPALIPDAENLKVTLERAM
PYWEEKIAPALLDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFELDEKLNIVKEYYLGGE

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=232, Percent_Identity=50.8620689655172, Blast_Score=250, Evalue=7e-67,
Organism=Homo sapiens, GI4502445, Length=233, Percent_Identity=48.9270386266094, Blast_Score=236, Evalue=1e-62,
Organism=Homo sapiens, GI40353764, Length=233, Percent_Identity=48.9270386266094, Blast_Score=236, Evalue=1e-62,
Organism=Homo sapiens, GI4505753, Length=232, Percent_Identity=50.8620689655172, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI71274132, Length=232, Percent_Identity=48.2758620689655, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI310129614, Length=161, Percent_Identity=53.416149068323, Blast_Score=166, Evalue=2e-41,
Organism=Escherichia coli, GI1786970, Length=229, Percent_Identity=55.0218340611354, Blast_Score=263, Evalue=9e-72,
Organism=Saccharomyces cerevisiae, GI6322697, Length=232, Percent_Identity=52.5862068965517, Blast_Score=256, Evalue=3e-69,
Organism=Saccharomyces cerevisiae, GI6324516, Length=279, Percent_Identity=31.8996415770609, Blast_Score=129, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6320183, Length=285, Percent_Identity=28.7719298245614, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324857, Length=195, Percent_Identity=27.1794871794872, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24646216, Length=221, Percent_Identity=54.7511312217195, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI85725270, Length=233, Percent_Identity=50.6437768240343, Blast_Score=232, Evalue=1e-61,
Organism=Drosophila melanogaster, GI85725272, Length=233, Percent_Identity=50.6437768240343, Blast_Score=232, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24650981, Length=233, Percent_Identity=50.6437768240343, Blast_Score=232, Evalue=1e-61,
Organism=Drosophila melanogaster, GI28571815, Length=220, Percent_Identity=40, Blast_Score=173, Evalue=8e-44,
Organism=Drosophila melanogaster, GI28571817, Length=220, Percent_Identity=40, Blast_Score=173, Evalue=8e-44,
Organism=Drosophila melanogaster, GI24648979, Length=220, Percent_Identity=40, Blast_Score=173, Evalue=9e-44,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 26037; Mature: 26037

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEFDLAFTSVLTR
CEEEEEECCCCCCCCCCEEEECEECCCCCCCCHHHHHHHHHHHHHHCCEEEHHHHHHHHH
AIKTTNLALENAGQLWVPTEKSWRLNERHYGALTGKNKAEAAEQFGDEQVHIWRRSYDVL
HHHHHHHEECCCCCEEECCCCCCCCCCCCCEEECCCCHHHHHHHCCCCEEEEEECCCCCC
PPAMAKDDEYSAHKDRRYADLDPALIPDAENLKVTLERAMPYWEEKIAPALLDGKNVFVG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHCCHHHHHCCHHEECCCEEEEE
AHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFELDEKLNIVKEYYLGGE
CCCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEFDLAFTSVLTR
CEEEEEECCCCCCCCCCEEEECEECCCCCCCCHHHHHHHHHHHHHHCCEEEHHHHHHHHH
AIKTTNLALENAGQLWVPTEKSWRLNERHYGALTGKNKAEAAEQFGDEQVHIWRRSYDVL
HHHHHHHEECCCCCEEECCCCCCCCCCCCCEEECCCCHHHHHHHCCCCEEEEEECCCCCC
PPAMAKDDEYSAHKDRRYADLDPALIPDAENLKVTLERAMPYWEEKIAPALLDGKNVFVG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHCCHHHHHCCHHEECCCEEEEE
AHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFELDEKLNIVKEYYLGGE
CCCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]