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The map label for this gene is clcB [H]

Identifier: 71910938

GI number: 71910938

Start: 1101685

End: 1102998

Strand: Direct

Name: clcB [H]

Synonym: M5005_Spy_1125

Alternate gene names: 71910938

Gene position: 1101685-1102998 (Clockwise)

Preceding gene: 71910937

Following gene: 71910939

Centisome position: 59.92

GC content: 41.4

Gene sequence:

>1314_bases
ATGACGATTATAATTATGGACTCTAATAGTGCTCACGAGACTGATAATCTATCAGTCTCTTTTCTTAACTTTTGTTATAA
TAGTCTTATGAAACGACACTTTTTACTCTTGACCTTTTACCTCTTTTTAACAGGTTTAACAGCTGGCCTTGTTGCTTTTA
TCTTAACAAAAGCCATTCACCTGATTCAGTCCCTCAGTTTTGGATTCAGTCAAGGTTCTTTTAGCACTATGATTGCTAGT
GTTCCACCACAAAGACGAGCTCTTTCACTCCTCTTTGCTGGACTTCTTGCAGGTCTTGGGTGGCACCTATTGGCTAAAAA
AGGAAAGGACATTCAATCTATTCAGCAAATCATTCAAGATGACATCTCATTTAGTCCCTGGACACAGTTTTGGCATGGTT
GGCTCCAATTAACGACCGTATCTATGGGAGCTCCTGTCGGCCGAGAAGGAGCTTCACGGGAAGTCGCTGTTACCTTGACG
TCTCTTTGGAGCCAAAGATGCAACTTGTCAAAAGCCGATCAAAAACTTTTATTAGCCTGCGCTTCTGGCGCTGCCCTTGG
TGCTGTCTACAATGCTCCCTTAGCCACTATTTTATTTATCTTAGAAGCTATTCTTAACCGTTGGTCCCTTAAAAATATAT
ACGCTGCCTGCCTAACGAGCTATGTGGCTGTGGAAACAGTTGCTTTATTACAAGGCCGACATGAGATTCAATACCTAATG
CCTCAGCAACATTGGACGCTAGGAACCCTTATTGGGTCCGTCCTGGCTGGTCTTATCCTTTCCCTCTTTGCTCACGCTTA
CAAACATCTTTTGAAACACCTTCCTAAGGCTGATGCCAAAAGTCAGTGGTTTATTCCGAAAGTTCTCATCGCTTTTAGCC
TTATCGCAGGACTCAGCATTTTCTTCCCAGAGATTTTAGGAAATGGCAAAGCTGGATTACTCTTTTTTCTCCATGAAGAA
CCACATCTGAGCTATATTAGCTGGCTACTTGTTGCCAAAGCTGTCGCTATCTCTTTAGTTTTTGCTTCTGGAGCAAAAGG
GGGTAAAATTGCTCCTTCTATGATGCTTGGAGGTGCTAGTGGCTTACTACTAGCTATCCTTAGTCAGTACCTTATTCCCT
TGTCTCTATCAAATACGTTAGCCATTATGGTTGGTGCAACAATCTTTTTAGGTGTGATCAATAAGATACCCTTGGCGGCA
CCAGTTTTTCTGGTTGAAATTACAGGCCAATCGTTACTAATGATTATCCCTTTAGCATTAGCTAACCTCATTTTTTATTT
TAGCTATCAGTTTTATCGTTTCATCCTTAAATGA

Upstream 100 bases:

>100_bases
CCAATTGTTATGAATGGTATTTCAACAGGAACATCAAACCATGACTTTTTCTCACAGGTAGGGAATGGCTATCTTCTTGG
TTCTGTAGAAGCTATGTCTG

Downstream 100 bases:

>100_bases
TTAGTTAATTACTTTTTTAATAAAAAGCTTCGGATGAATGAACTGCACCCCAAAAGTTGGACATTATATTTTAAGCAAAG
TTGGACTTGGTATAATAAAG

Product: chloride channel protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTIIIMDSNSAHETDNLSVSFLNFCYNSLMKRHFLLLTFYLFLTGLTAGLVAFILTKAIHLIQSLSFGFSQGSFSTMIAS
VPPQRRALSLLFAGLLAGLGWHLLAKKGKDIQSIQQIIQDDISFSPWTQFWHGWLQLTTVSMGAPVGREGASREVAVTLT
SLWSQRCNLSKADQKLLLACASGAALGAVYNAPLATILFILEAILNRWSLKNIYAACLTSYVAVETVALLQGRHEIQYLM
PQQHWTLGTLIGSVLAGLILSLFAHAYKHLLKHLPKADAKSQWFIPKVLIAFSLIAGLSIFFPEILGNGKAGLLFFLHEE
PHLSYISWLLVAKAVAISLVFASGAKGGKIAPSMMLGGASGLLLAILSQYLIPLSLSNTLAIMVGATIFLGVINKIPLAA
PVFLVEITGQSLLMIIPLALANLIFYFSYQFYRFILK

Sequences:

>Translated_437_residues
MTIIIMDSNSAHETDNLSVSFLNFCYNSLMKRHFLLLTFYLFLTGLTAGLVAFILTKAIHLIQSLSFGFSQGSFSTMIAS
VPPQRRALSLLFAGLLAGLGWHLLAKKGKDIQSIQQIIQDDISFSPWTQFWHGWLQLTTVSMGAPVGREGASREVAVTLT
SLWSQRCNLSKADQKLLLACASGAALGAVYNAPLATILFILEAILNRWSLKNIYAACLTSYVAVETVALLQGRHEIQYLM
PQQHWTLGTLIGSVLAGLILSLFAHAYKHLLKHLPKADAKSQWFIPKVLIAFSLIAGLSIFFPEILGNGKAGLLFFLHEE
PHLSYISWLLVAKAVAISLVFASGAKGGKIAPSMMLGGASGLLLAILSQYLIPLSLSNTLAIMVGATIFLGVINKIPLAA
PVFLVEITGQSLLMIIPLALANLIFYFSYQFYRFILK
>Mature_436_residues
TIIIMDSNSAHETDNLSVSFLNFCYNSLMKRHFLLLTFYLFLTGLTAGLVAFILTKAIHLIQSLSFGFSQGSFSTMIASV
PPQRRALSLLFAGLLAGLGWHLLAKKGKDIQSIQQIIQDDISFSPWTQFWHGWLQLTTVSMGAPVGREGASREVAVTLTS
LWSQRCNLSKADQKLLLACASGAALGAVYNAPLATILFILEAILNRWSLKNIYAACLTSYVAVETVALLQGRHEIQYLMP
QQHWTLGTLIGSVLAGLILSLFAHAYKHLLKHLPKADAKSQWFIPKVLIAFSLIAGLSIFFPEILGNGKAGLLFFLHEEP
HLSYISWLLVAKAVAISLVFASGAKGGKIAPSMMLGGASGLLLAILSQYLIPLSLSNTLAIMVGATIFLGVINKIPLAAP
VFLVEITGQSLLMIIPLALANLIFYFSYQFYRFILK

Specific function: Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response [H]

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 47718; Mature: 47587

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIIIMDSNSAHETDNLSVSFLNFCYNSLMKRHFLLLTFYLFLTGLTAGLVAFILTKAIH
CEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIQSLSFGFSQGSFSTMIASVPPQRRALSLLFAGLLAGLGWHLLAKKGKDIQSIQQIIQD
HHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
DISFSPWTQFWHGWLQLTTVSMGAPVGREGASREVAVTLTSLWSQRCNLSKADQKLLLAC
CCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
ASGAALGAVYNAPLATILFILEAILNRWSLKNIYAACLTSYVAVETVALLQGRHEIQYLM
HCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHC
PQQHWTLGTLIGSVLAGLILSLFAHAYKHLLKHLPKADAKSQWFIPKVLIAFSLIAGLSI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
FFPEILGNGKAGLLFFLHEEPHLSYISWLLVAKAVAISLVFASGAKGGKIAPSMMLGGAS
HHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCH
GLLLAILSQYLIPLSLSNTLAIMVGATIFLGVINKIPLAAPVFLVEITGQSLLMIIPLAL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHH
ANLIFYFSYQFYRFILK
HHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TIIIMDSNSAHETDNLSVSFLNFCYNSLMKRHFLLLTFYLFLTGLTAGLVAFILTKAIH
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIQSLSFGFSQGSFSTMIASVPPQRRALSLLFAGLLAGLGWHLLAKKGKDIQSIQQIIQD
HHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
DISFSPWTQFWHGWLQLTTVSMGAPVGREGASREVAVTLTSLWSQRCNLSKADQKLLLAC
CCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
ASGAALGAVYNAPLATILFILEAILNRWSLKNIYAACLTSYVAVETVALLQGRHEIQYLM
HCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHC
PQQHWTLGTLIGSVLAGLILSLFAHAYKHLLKHLPKADAKSQWFIPKVLIAFSLIAGLSI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
FFPEILGNGKAGLLFFLHEEPHLSYISWLLVAKAVAISLVFASGAKGGKIAPSMMLGGAS
HHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCH
GLLLAILSQYLIPLSLSNTLAIMVGATIFLGVINKIPLAAPVFLVEITGQSLLMIIPLAL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHH
ANLIFYFSYQFYRFILK
HHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA