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The map label for this gene is dnaC [H]

Identifier: 71910855

GI number: 71910855

Start: 1013925

End: 1014707

Strand: Reverse

Name: dnaC [H]

Synonym: M5005_Spy_1042

Alternate gene names: 71910855

Gene position: 1014707-1013925 (Counterclockwise)

Preceding gene: 71910856

Following gene: 71910854

Centisome position: 55.19

GC content: 39.21

Gene sequence:

>783_bases
ATGATACTTGGTGACGAAGACGCACTTGCTAAAATCGCTATATCTTATCAACAAAACACCAAGAAAGAAGATGCTGTCTG
TGAAAAACATGGTTGTAGATACATCACAGTCCTCAAGACTGGTTTGACAGTATGTCCAGATTGTCACAGAGAAGAATTAG
ACAATCAAAACGCTTTGCACGTCCAAAAGCAATATGAGAGAGAGCTTGAAAACAAGCGACTGTACTATCTCAAAAAATTA
TCAATTATGGACGACGAGTTGGAAAATGCATCATTTGACAATTTTAGGGCTGATACGGCTAAACACAAAGAGATGCTTTA
TTGGGCAAAGACAATGGCTAACGATTGGTTTAGTGGTGGTAAGGGAAACATCATCATGACTGGCAAAGCAGGACGAGGCA
AAAGTCATTTAGCTTATAGCATCATTAGGGGATTGTCTGATAAAACGAAAAAATTAGGCTTGCTTGTAAATGTCACTGAC
TTACTGTCAGAGATAAAGCGAGACTTTAGCAAGGAAGCATTTTGGATGGATAAGCTAAAAGATGTCGATTATCTGGTGCT
AGATGATCTAGGTGCCGAAAAAGTTAGTGACTGGTCCACAAGCATTATTTACAGCTTGCTTAACAAGCGCACAAACACAA
TCATTACTACCAATCTGACACCTGCCGAAATTAGAAAAATTTATGGAGAGAGAATTGCATCCCGTATCAGAAAAGGCTGC
GACAAAAGTCATATCATGGAATTTGATGGCATGGAGGACGAAAGGATGAAGCTATGGAATTGA

Upstream 100 bases:

>100_bases
CGAAATTGGAGACAAAACGGAATCCTTACGATGGTTAAAGTTGAAGAAGAACAAAGGCAATTCCAATCTAGAAAATCTAA
ACAAGAAGAGGTATCGGAAT

Downstream 100 bases:

>100_bases
CACTAACAACATTTTTCGGGCTATCCGAGGAACATGCGGCAAAAATCATGGCGCTAGATGAAGATGTCCGAACAAAGAAA
ATTGAAGAATTGAGAGCGTG

Product: phage replication protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MILGDEDALAKIAISYQQNTKKEDAVCEKHGCRYITVLKTGLTVCPDCHREELDNQNALHVQKQYERELENKRLYYLKKL
SIMDDELENASFDNFRADTAKHKEMLYWAKTMANDWFSGGKGNIIMTGKAGRGKSHLAYSIIRGLSDKTKKLGLLVNVTD
LLSEIKRDFSKEAFWMDKLKDVDYLVLDDLGAEKVSDWSTSIIYSLLNKRTNTIITTNLTPAEIRKIYGERIASRIRKGC
DKSHIMEFDGMEDERMKLWN

Sequences:

>Translated_260_residues
MILGDEDALAKIAISYQQNTKKEDAVCEKHGCRYITVLKTGLTVCPDCHREELDNQNALHVQKQYERELENKRLYYLKKL
SIMDDELENASFDNFRADTAKHKEMLYWAKTMANDWFSGGKGNIIMTGKAGRGKSHLAYSIIRGLSDKTKKLGLLVNVTD
LLSEIKRDFSKEAFWMDKLKDVDYLVLDDLGAEKVSDWSTSIIYSLLNKRTNTIITTNLTPAEIRKIYGERIASRIRKGC
DKSHIMEFDGMEDERMKLWN
>Mature_260_residues
MILGDEDALAKIAISYQQNTKKEDAVCEKHGCRYITVLKTGLTVCPDCHREELDNQNALHVQKQYERELENKRLYYLKKL
SIMDDELENASFDNFRADTAKHKEMLYWAKTMANDWFSGGKGNIIMTGKAGRGKSHLAYSIIRGLSDKTKKLGLLVNVTD
LLSEIKRDFSKEAFWMDKLKDVDYLVLDDLGAEKVSDWSTSIIYSLLNKRTNTIITTNLTPAEIRKIYGERIASRIRKGC
DKSHIMEFDGMEDERMKLWN

Specific function: This protein is required for chromosomal replication. It forms, in concert with dnaB protein and other prepriming proteins dnaT, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' [H]

COG id: COG1484

COG function: function code L; DNA replication protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaC family [H]

Homologues:

Organism=Escherichia coli, GI1790823, Length=160, Percent_Identity=31.25, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787623, Length=154, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR002611 [H]

Pfam domain/function: PF01695 IstB [H]

EC number: NA

Molecular weight: Translated: 29976; Mature: 29976

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILGDEDALAKIAISYQQNTKKEDAVCEKHGCRYITVLKTGLTVCPDCHREELDNQNALH
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHCCCCCCCH
VQKQYERELENKRLYYLKKLSIMDDELENASFDNFRADTAKHKEMLYWAKTMANDWFSGG
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
KGNIIMTGKAGRGKSHLAYSIIRGLSDKTKKLGLLVNVTDLLSEIKRDFSKEAFWMDKLK
CCCEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHC
DVDYLVLDDLGAEKVSDWSTSIIYSLLNKRTNTIITTNLTPAEIRKIYGERIASRIRKGC
CCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCC
DKSHIMEFDGMEDERMKLWN
CHHHEECCCCCCHHHHHCCC
>Mature Secondary Structure
MILGDEDALAKIAISYQQNTKKEDAVCEKHGCRYITVLKTGLTVCPDCHREELDNQNALH
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHCCCCCCCH
VQKQYERELENKRLYYLKKLSIMDDELENASFDNFRADTAKHKEMLYWAKTMANDWFSGG
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
KGNIIMTGKAGRGKSHLAYSIIRGLSDKTKKLGLLVNVTDLLSEIKRDFSKEAFWMDKLK
CCCEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHC
DVDYLVLDDLGAEKVSDWSTSIIYSLLNKRTNTIITTNLTPAEIRKIYGERIASRIRKGC
CCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCC
DKSHIMEFDGMEDERMKLWN
CHHHEECCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]