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The map label for this gene is bcc [H]

Identifier: 71910709

GI number: 71910709

Start: 884662

End: 885012

Strand: Direct

Name: bcc [H]

Synonym: M5005_Spy_0896

Alternate gene names: 71910709

Gene position: 884662-885012 (Clockwise)

Preceding gene: 71910708

Following gene: 71910710

Centisome position: 48.12

GC content: 42.45

Gene sequence:

>351_bases
ATGAAAAGATATGAAGTGACTGTCAATGGACAGGTTTATGAAGTGAGTTTACGTGAACTAGTTGATGGAGAAACTGTTGA
AGTTAGCCAGCCAGCAGCACCCGCTACTGAGAAAGAAATGAATGCCAACGCTGCTGGCGGTGGCATTCAGGTAAAGGCTC
CAATGTCTGGAACAGTCTTGTCTATCTTTGCTACAGAAGGAAAAGCTGTTAAAAAAGGAGAAGCTGTTCTGGTCTTAGAG
GCCATGAAAATGGAGAATGAAATTCTAGCACCTGCAGATGGTCTGGTTTCAAAAATTCATGTTGTGGCTAACCAAACGGT
CGAGTCTGAACAAGTTTTGATTTCATTCTAG

Upstream 100 bases:

>100_bases
ACGAATTGGCTAGAATTGCTGTTATGACTAGTCTTGCTTATGCTAGCCAAGAAGAGTCAGGAAAACGGTTTGAAGTTATT
GCCGTGGAAAGGAAATCCTA

Downstream 100 bases:

>100_bases
GAGGAAACCATGCTAGACGTACTCAATCAAATGGTCCAATCGTCAGGATTGGCTCATCTAACTGTTAATAATCTTATCAT
GATTTGCTTGGCCAGTTTCT

Product: biotin carboxyl carrier protein of oxaloacetate decarboxylase

Products: propanoyl-CoA; CO2

Alternate protein names: BCCP [H]

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MKRYEVTVNGQVYEVSLRELVDGETVEVSQPAAPATEKEMNANAAGGGIQVKAPMSGTVLSIFATEGKAVKKGEAVLVLE
AMKMENEILAPADGLVSKIHVVANQTVESEQVLISF

Sequences:

>Translated_116_residues
MKRYEVTVNGQVYEVSLRELVDGETVEVSQPAAPATEKEMNANAAGGGIQVKAPMSGTVLSIFATEGKAVKKGEAVLVLE
AMKMENEILAPADGLVSKIHVVANQTVESEQVLISF
>Mature_116_residues
MKRYEVTVNGQVYEVSLRELVDGETVEVSQPAAPATEKEMNANAAGGGIQVKAPMSGTVLSIFATEGKAVKKGEAVLVLE
AMKMENEILAPADGLVSKIHVVANQTVESEQVLISF

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl [H]

EC number: 4.1.1.41

Molecular weight: Translated: 12288; Mature: 12288

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYEVTVNGQVYEVSLRELVDGETVEVSQPAAPATEKEMNANAAGGGIQVKAPMSGTVL
CCEEEEEECCEEEEEEHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCEEE
SIFATEGKAVKKGEAVLVLEAMKMENEILAPADGLVSKIHVVANQTVESEQVLISF
EEEECCCCEEECCCEEEEEEEECCCCCCCCCCCHHHHEEEEEECCCCCCCEEEEEC
>Mature Secondary Structure
MKRYEVTVNGQVYEVSLRELVDGETVEVSQPAAPATEKEMNANAAGGGIQVKAPMSGTVL
CCEEEEEECCEEEEEEHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCEEE
SIFATEGKAVKKGEAVLVLEAMKMENEILAPADGLVSKIHVVANQTVESEQVLISF
EEEECCCCEEECCCEEEEEEEECCCCCCCCCCCHHHHEEEEEECCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-methylmalonyl-CoA

Specific reaction: (S)-methylmalonyl-CoA = propanoyl-CoA + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8431283; 12397186 [H]