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The map label for this gene is ywkD [H]

Identifier: 71910689

GI number: 71910689

Start: 868700

End: 869116

Strand: Direct

Name: ywkD [H]

Synonym: M5005_Spy_0876

Alternate gene names: 71910689

Gene position: 868700-869116 (Clockwise)

Preceding gene: 71910688

Following gene: 71910690

Centisome position: 47.25

GC content: 36.21

Gene sequence:

>417_bases
ATGATGAAACTAAATGCCATTCATCACGTTGCTATTATTGTATCTGATTATCATCTGTCAAAAGATTTTTATGTGAATAA
ACTCGGATTTGAAATTATCAGAGAAAATTATCGTCCTGACAAGCATGATTACAAATTAGATTTATCTTGTGGTCGTATTG
AATTGGAGATTTTTGGTAAGGTGACAAGTGACCCCAACTATCAAGCTCCTCCTAAACGTGTAAGTGAACCAGAATTTAAA
AGTGAGGCCTGTGGTTTGAGGCACCTTGCATTTCGTGTTACCAACATTGAGAGTTATGTAGATGATCTAAAGAGCTTAGG
AATTCCAGTGGAGCCTATCAGGCATGATGATTACACAGGTGAGAAAATGACTTTCTTTTTTGATCCGGATGGTTTGCCTT
TAGAATTACATGAATAG

Upstream 100 bases:

>100_bases
TATAACCAAGTATCTACCTAGATATATCTTAAATATAATATTTAAAAAGTAGGACCATAGAGAAAATTTATCTCATCCTA
CTTTTTTTGAAAGGAGAAAT

Downstream 100 bases:

>100_bases
ACTTATTAGGTTAACGACTGGATCGTGCTATAAAACTCGTTAAAAATAGTTATTTGTTGTATCTTCATTTGCTTGATTAA
TCTCTTTTGATCGTTAAATG

Product: lactoylglutathione lyase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MMKLNAIHHVAIIVSDYHLSKDFYVNKLGFEIIRENYRPDKHDYKLDLSCGRIELEIFGKVTSDPNYQAPPKRVSEPEFK
SEACGLRHLAFRVTNIESYVDDLKSLGIPVEPIRHDDYTGEKMTFFFDPDGLPLELHE

Sequences:

>Translated_138_residues
MMKLNAIHHVAIIVSDYHLSKDFYVNKLGFEIIRENYRPDKHDYKLDLSCGRIELEIFGKVTSDPNYQAPPKRVSEPEFK
SEACGLRHLAFRVTNIESYVDDLKSLGIPVEPIRHDDYTGEKMTFFFDPDGLPLELHE
>Mature_138_residues
MMKLNAIHHVAIIVSDYHLSKDFYVNKLGFEIIRENYRPDKHDYKLDLSCGRIELEIFGKVTSDPNYQAPPKRVSEPEFK
SEACGLRHLAFRVTNIESYVDDLKSLGIPVEPIRHDDYTGEKMTFFFDPDGLPLELHE

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87081697, Length=139, Percent_Identity=46.0431654676259, Blast_Score=115, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 16027; Mature: 16027

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00934 GLYOXALASE_I_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKLNAIHHVAIIVSDYHLSKDFYVNKLGFEIIRENYRPDKHDYKLDLSCGRIELEIFGK
CEEECCEEEEEEEEECCCCCCCEEEHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEEEEE
VTSDPNYQAPPKRVSEPEFKSEACGLRHLAFRVTNIESYVDDLKSLGIPVEPIRHDDYTG
ECCCCCCCCCCCCCCCCCCCHHHCCCEEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCC
EKMTFFFDPDGLPLELHE
CEEEEEECCCCCEEEECC
>Mature Secondary Structure
MMKLNAIHHVAIIVSDYHLSKDFYVNKLGFEIIRENYRPDKHDYKLDLSCGRIELEIFGK
CEEECCEEEEEEEEECCCCCCCEEEHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEEEEE
VTSDPNYQAPPKRVSEPEFKSEACGLRHLAFRVTNIESYVDDLKSLGIPVEPIRHDDYTG
ECCCCCCCCCCCCCCCCCCCHHHCCCEEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCC
EKMTFFFDPDGLPLELHE
CEEEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]