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The map label for this gene is bglP [H]

Identifier: 71910288

GI number: 71910288

Start: 464916

End: 466616

Strand: Direct

Name: bglP [H]

Synonym: M5005_Spy_0475

Alternate gene names: 71910288

Gene position: 464916-466616 (Clockwise)

Preceding gene: 71910287

Following gene: 71910289

Centisome position: 25.29

GC content: 43.56

Gene sequence:

>1701_bases
ATGCGCAAAAACGGCCAGTACCAAATTATCTTGGGCAATGATGTCAATAATTATTACCAAGCCTTTTTAAGCCTAGGGCA
TTTTGACAATCAAGATGAAGATCATTCTTCAAAAGCGAAAGGAAGTATCCTTGAGCGCTTGATTGAAACCATTGCTGGCG
TGATTACACCGCTGATTCCAGCCCTTCTTGGTGGTGGAATGCTCAAAGTGGTGGGAATCTTGCTTCCTATGCTTGGCTTA
GCGAGTGCGGACTCTCAAACCGTTGCCTTTATTAACTTCTTTGGCGATGCGGCTTATTATTTTATGCCTGTCATGATTGC
CTATTCAGCAGCGGCGCGCTTTAAGGTGACACCTGTTTTAGCAGCGACGATCGCAGGGATTTTATTGCATCCTGCCTTTG
TTGCAATGGTAGCAGAAGGTAAACCATTGACTTTATTTGGAGCACCAGTCACTCCTGCTAGCTATGGCTCATCTGTTATT
CCCATTTTGATGATGGTTTACTTGATGCAATACATTGAAAAATGGGTCAATCGCTTGGTGCCAAGCGTGATGAAAAGCTT
CTTACAGCCAACCTTAATCATTTTGATTTCTGGCTTTTTGGCTTTAGTGGTTGTAGGTCCTCTTGGTGTGATTATTGGTC
AAGGGTTATCTAATACCATGCTCGCTATTTATCATGTGGCTCCGTGGCTAGCACTTGCTATTTTGGGAGCGATTATGCCG
CTTGTTGTCATGACGGGGATGCACTGGGCTTTTGCACCAATCTTTTTGGCCGCTTCGGTCGCAACACCAGATGTCTTGAT
TTTACCAGCAATGTTGGCTTCTAATTTGGCTCAAGGAGCCGCATCTTTGGCTGTTGCCTTTAAAACAAAGCAGAAACAAA
CACGTCAAGTTGCCCTTGCCGCGGGGATTTCAGCTTTGCTGGCAGGTATCACGGAACCGGCACTTTATGGGGTCACACTG
AAATTTAAAAAGCCACTCTATGCAGCCATGATTTCAGGTGGTCTGGTTGGAGCCTTTATTGGTTTTGTCAATATTGCTTC
TTATACCTTTGTCGTACCTTCTATTATTGGTTTACCACAGTACATCAACCCATCAGGCGGAGCTAATTTTACAAATGCTT
TGATTGCCGGAACTGCGACGATTGTGTTAGCCTTCAGTTTGACTTGGTTCATGGGAATTGATGAAGAGTCCCCAAAGCAA
GTGAGTGTTGCAGCAGATATGTCACAAGTTAAGAGCGGCTTGTCAACCAAACAAACGTTGTATGCTCCAATGACAGGTGA
GATGCTTTTTCTATCAGAAGTTCCTGATGAAACCTTTTCTTCCAAGTTATTAGGAGAAGGATTTGCCATATTACCAAGCG
AAGGTGAGGTCTATGCCCCCTTTGATGGTGAAGTCATCACTTTCTTTCCAACCAAGCATGCTGTTGCCTTAAAAAACACA
CGTGGTGTGGAAGTCTTGATTCATGTCGGTATTGATACGGTTGAGTTAAAAGGGCAAGGTTTCGAGCAGTTAGTGTCTGT
TGGCGATGTCGTGAAACGAGGCCAGGCACTTCTAAAAATGGATATTGATTTCATTACTTCAAAAGGCTATTCACTCATCA
GTCCTGTGGTCGTGACCAATTCGGCTGAGCAGTTGGAGATTATTATTCAAGATGACAAAAAAATGGTGACTAAAGAGGAC
GCTTTGTTAGTCATTTTATAA

Upstream 100 bases:

>100_bases
ACGTGTGACACACTGTGTAACACGTCTACGCTTAGTACTGAAAAATGATGAGAAAGTTAAAGATCAGCAAGTCAAAGCCA
TTTCAAATGTGATTGGCGTG

Downstream 100 bases:

>100_bases
CCTAAAAGGAGAGGGAGAATGGGAATTTTTCCAAAAGATTTCTTATGGGGCGGCGCAGTAGCTGCCAACCAAGTGGAAGG
AGCATTTGAGGCAGACGCAA

Product: PTS system, beta-glucoside-specific IIABC component

Products: NA

Alternate protein names: EIIBCA-Bgl; EII-Bgl; Beta-glucoside-specific phosphotransferase enzyme IIB component; PTS system beta-glucoside-specific EIIB component; Beta-glucoside permease IIC component; PTS system beta-glucoside-specific EIIC component; Beta-glucoside-specific phosphotransferase enzyme IIA component; PTS system beta-glucoside-specific EIIA component [H]

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MRKNGQYQIILGNDVNNYYQAFLSLGHFDNQDEDHSSKAKGSILERLIETIAGVITPLIPALLGGGMLKVVGILLPMLGL
ASADSQTVAFINFFGDAAYYFMPVMIAYSAAARFKVTPVLAATIAGILLHPAFVAMVAEGKPLTLFGAPVTPASYGSSVI
PILMMVYLMQYIEKWVNRLVPSVMKSFLQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLAIYHVAPWLALAILGAIMP
LVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGAASLAVAFKTKQKQTRQVALAAGISALLAGITEPALYGVTL
KFKKPLYAAMISGGLVGAFIGFVNIASYTFVVPSIIGLPQYINPSGGANFTNALIAGTATIVLAFSLTWFMGIDEESPKQ
VSVAADMSQVKSGLSTKQTLYAPMTGEMLFLSEVPDETFSSKLLGEGFAILPSEGEVYAPFDGEVITFFPTKHAVALKNT
RGVEVLIHVGIDTVELKGQGFEQLVSVGDVVKRGQALLKMDIDFITSKGYSLISPVVVTNSAEQLEIIIQDDKKMVTKED
ALLVIL

Sequences:

>Translated_566_residues
MRKNGQYQIILGNDVNNYYQAFLSLGHFDNQDEDHSSKAKGSILERLIETIAGVITPLIPALLGGGMLKVVGILLPMLGL
ASADSQTVAFINFFGDAAYYFMPVMIAYSAAARFKVTPVLAATIAGILLHPAFVAMVAEGKPLTLFGAPVTPASYGSSVI
PILMMVYLMQYIEKWVNRLVPSVMKSFLQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLAIYHVAPWLALAILGAIMP
LVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGAASLAVAFKTKQKQTRQVALAAGISALLAGITEPALYGVTL
KFKKPLYAAMISGGLVGAFIGFVNIASYTFVVPSIIGLPQYINPSGGANFTNALIAGTATIVLAFSLTWFMGIDEESPKQ
VSVAADMSQVKSGLSTKQTLYAPMTGEMLFLSEVPDETFSSKLLGEGFAILPSEGEVYAPFDGEVITFFPTKHAVALKNT
RGVEVLIHVGIDTVELKGQGFEQLVSVGDVVKRGQALLKMDIDFITSKGYSLISPVVVTNSAEQLEIIIQDDKKMVTKED
ALLVIL
>Mature_566_residues
MRKNGQYQIILGNDVNNYYQAFLSLGHFDNQDEDHSSKAKGSILERLIETIAGVITPLIPALLGGGMLKVVGILLPMLGL
ASADSQTVAFINFFGDAAYYFMPVMIAYSAAARFKVTPVLAATIAGILLHPAFVAMVAEGKPLTLFGAPVTPASYGSSVI
PILMMVYLMQYIEKWVNRLVPSVMKSFLQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLAIYHVAPWLALAILGAIMP
LVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGAASLAVAFKTKQKQTRQVALAAGISALLAGITEPALYGVTL
KFKKPLYAAMISGGLVGAFIGFVNIASYTFVVPSIIGLPQYINPSGGANFTNALIAGTATIVLAFSLTWFMGIDEESPKQ
VSVAADMSQVKSGLSTKQTLYAPMTGEMLFLSEVPDETFSSKLLGEGFAILPSEGEVYAPFDGEVITFFPTKHAVALKNT
RGVEVLIHVGIDTVELKGQGFEQLVSVGDVVKRGQALLKMDIDFITSKGYSLISPVVVTNSAEQLEIIIQDDKKMVTKED
ALLVIL

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790159, Length=581, Percent_Identity=33.9070567986231, Blast_Score=305, Evalue=6e-84,
Organism=Escherichia coli, GI48994906, Length=417, Percent_Identity=38.1294964028777, Blast_Score=279, Evalue=4e-76,
Organism=Escherichia coli, GI2367362, Length=365, Percent_Identity=29.5890410958904, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786894, Length=146, Percent_Identity=39.7260273972603, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1788757, Length=129, Percent_Identity=39.5348837209302, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788769, Length=321, Percent_Identity=26.1682242990654, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011297 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 60216; Mature: 60216

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKNGQYQIILGNDVNNYYQAFLSLGHFDNQDEDHSSKAKGSILERLIETIAGVITPLIP
CCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALLGGGMLKVVGILLPMLGLASADSQTVAFINFFGDAAYYFMPVMIAYSAAARFKVTPVL
HHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCEEEHHHH
AATIAGILLHPAFVAMVAEGKPLTLFGAPVTPASYGSSVIPILMMVYLMQYIEKWVNRLV
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
PSVMKSFLQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLAIYHVAPWLALAILGAIMP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGAASLAVAFKTKQKQTRQVALA
HHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGISALLAGITEPALYGVTLKFKKPLYAAMISGGLVGAFIGFVNIASYTFVVPSIIGLPQ
HHHHHHHHHCCCCHHEEEEEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC
YINPSGGANFTNALIAGTATIVLAFSLTWFMGIDEESPKQVSVAADMSQVKSGLSTKQTL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHCCCCCCCEE
YAPMTGEMLFLSEVPDETFSSKLLGEGFAILPSEGEVYAPFDGEVITFFPTKHAVALKNT
ECCCCCCEEEEECCCCHHHHHHHHCCCEEEECCCCCEECCCCCCEEEEECCCCEEEEECC
RGVEVLIHVGIDTVELKGQGFEQLVSVGDVVKRGQALLKMDIDFITSKGYSLISPVVVTN
CCEEEEEEECCCEEEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHCCEEEEC
SAEQLEIIIQDDKKMVTKEDALLVIL
CHHHEEEEEECCCHHHCCCCCEEEEC
>Mature Secondary Structure
MRKNGQYQIILGNDVNNYYQAFLSLGHFDNQDEDHSSKAKGSILERLIETIAGVITPLIP
CCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALLGGGMLKVVGILLPMLGLASADSQTVAFINFFGDAAYYFMPVMIAYSAAARFKVTPVL
HHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCEEEHHHH
AATIAGILLHPAFVAMVAEGKPLTLFGAPVTPASYGSSVIPILMMVYLMQYIEKWVNRLV
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
PSVMKSFLQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLAIYHVAPWLALAILGAIMP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGAASLAVAFKTKQKQTRQVALA
HHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGISALLAGITEPALYGVTLKFKKPLYAAMISGGLVGAFIGFVNIASYTFVVPSIIGLPQ
HHHHHHHHHCCCCHHEEEEEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC
YINPSGGANFTNALIAGTATIVLAFSLTWFMGIDEESPKQVSVAADMSQVKSGLSTKQTL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHCCCCCCCEE
YAPMTGEMLFLSEVPDETFSSKLLGEGFAILPSEGEVYAPFDGEVITFFPTKHAVALKNT
ECCCCCCEEEEECCCCHHHHHHHHCCCEEEECCCCCEECCCCCCEEEEECCCCEEEEECC
RGVEVLIHVGIDTVELKGQGFEQLVSVGDVVKRGQALLKMDIDFITSKGYSLISPVVVTN
CCEEEEEEECCCEEEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHCCEEEEC
SAEQLEIIIQDDKKMVTKEDALLVIL
CHHHEEEEEECCCHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7883710; 7704263; 9384377; 8628237 [H]