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The map label for this gene is mtlF [H]

Identifier: 71893903

GI number: 71893903

Start: 716116

End: 716544

Strand: Reverse

Name: mtlF [H]

Synonym: MHJ_0552

Alternate gene names: 71893903

Gene position: 716544-716116 (Counterclockwise)

Preceding gene: 71893904

Following gene: 71893902

Centisome position: 79.85

GC content: 27.97

Gene sequence:

>429_bases
ATGAATTTAAAACTCGAAAATATTCATTTAAATCAAATTATTACCTCAAAAAAGCAAGCTTTTGAAAAATTAATTAGAAT
TTTCCAACAAAAAAACTGTTGTGAATTTGAATATTTGCAGTCAATGGAAAAACGAGACCTGGAATCTTCAGTAGCTTTAG
GAAATTTTTTAGCCTTACCGCACGGAAATTTTGAAGGAAATAATCTAATTTTTAGAAATTGCATCGAAATTGTCCACCTC
AAAAACACACTTAATTGAGACGGCCAACCTGTTAAATTTGTTATTGGGCTTGCGGTTAAAGATTCTGAACAAATTGATTA
TATTCAAAAAATCGGCCTTGCCTTTATTGATGTAGAAAAAGTTGAAGAAATTCTGAATGATTCTGATTTATCAAAGCAAA
AAATTTTAGATTGAATTATAAATAATTAA

Upstream 100 bases:

>100_bases
AAAGTCCCGAATTTTTCCTAAAAAATCAAACAAATTTAGATATAAATGAAATTAAATTAGTGCTAAATTTTTATAAAAAT
CAAAAGAAAAGGCTGAAAAA

Downstream 100 bases:

>100_bases
AAAAAAGCATATTTTTAATGCTTTTTTGTTTTAACTAGCTTCTTTAAGCAAAATTCAATGTGTTAAAATTTTATTTTAGT
TTCTTAAATTTAGAGTTAAA

Product: PTS system mannitol-specific transporter subunit IIA

Products: protein histidine; sugar phosphate

Alternate protein names: EIIA-Mtl; EIII-Mtl; PTS system mannitol-specific EIIA component [H]

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MNLKLENIHLNQIITSKKQAFEKLIRIFQQKNCCEFEYLQSMEKRDLESSVALGNFLALPHGNFEGNNLIFRNCIEIVHL
KNTLNWDGQPVKFVIGLAVKDSEQIDYIQKIGLAFIDVEKVEEILNDSDLSKQKILDWIINN

Sequences:

>Translated_142_residues
MNLKLENIHLNQIITSKKQAFEKLIRIFQQKNCCEFEYLQSMEKRDLESSVALGNFLALPHGNFEGNNLIFRNCIEIVHL
KNTLN*DGQPVKFVIGLAVKDSEQIDYIQKIGLAFIDVEKVEEILNDSDLSKQKILD*IINN
>Mature_142_residues
MNLKLENIHLNQIITSKKQAFEKLIRIFQQKNCCEFEYLQSMEKRDLESSVALGNFLALPHGNFEGNNLIFRNCIEIVHL
KNTLN*DGQPVKFVIGLAVKDSEQIDYIQKIGLAFIDVEKVEEILNDSDLSKQKILD*IINN

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG4668

COG function: function code G; Mannitol/fructose-specific phosphotransferase system, IIA domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178 [H]

Pfam domain/function: PF00359 PTS_EIIA_2 [H]

EC number: 2.7.1.69

Molecular weight: Translated: 16070; Mature: 16070

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00372 PTS_EIIA_TYPE_2_HIS ; PS51094 PTS_EIIA_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKLENIHLNQIITSKKQAFEKLIRIFQQKNCCEFEYLQSMEKRDLESSVALGNFLALP
CCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEECC
HGNFEGNNLIFRNCIEIVHLKNTLNDGQPVKFVIGLAVKDSEQIDYIQKIGLAFIDVEKV
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCHHHH
EEILNDSDLSKQKILDIINN
HHHHCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MNLKLENIHLNQIITSKKQAFEKLIRIFQQKNCCEFEYLQSMEKRDLESSVALGNFLALP
CCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEECC
HGNFEGNNLIFRNCIEIVHLKNTLNDGQPVKFVIGLAVKDSEQIDYIQKIGLAFIDVEKV
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCHHHH
EEILNDSDLSKQKILDIINN
HHHHCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]