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The map label for this gene is upp [H]

Identifier: 71893878

GI number: 71893878

Start: 681043

End: 681657

Strand: Reverse

Name: upp [H]

Synonym: MHJ_0527

Alternate gene names: 71893878

Gene position: 681657-681043 (Counterclockwise)

Preceding gene: 71893879

Following gene: 71893877

Centisome position: 75.96

GC content: 30.57

Gene sequence:

>615_bases
ATGGAAATAAAAGTTGATCATCCTTTAATTGATAGTGAAATTGCTAGAATAAGGCAAATGACAACGTTAAAAGATTTCCG
CAATTCGATTAAAAAAATATCAAAATTGCTTGCTTTTCCAGTTTTATCTAGATTAGAAACAGAAGAATTTAGAGCTAAAT
CGGTATTAGGTCATGAATTTTTAGGTCATAAAATTATTACAAAACTCGTTTTTATTCCGATTTTAAGGGCCGGTTTTGGT
ATGCTTGACTCCTTTCTTGAACTTGCTCCCTATGCTAAAGTTGCACCAATTGGTTTAAAAAGAAATTCAGATTTATCAAT
TCAGACTTATTTTGAAAGTTTGCCACAAGCAAATCCTAATTCAGTTGCGATTGTTTTAGAGCCTATTTTAGCAACAGGGA
ATACTTTAATCCGTGCAATTGAAATAATTCTTGAAAAAGGATATAAAAAAATAGTGATTGCAACGATGTTAACAGTTCAG
GTAGGAATTGATAAAATATTAGAACGATATCCGCAAATTTCAATATTTTTCTGTCAAAAAGATCCAAAATTAAACAATAA
AGGATATATAATTCCAGGAATTGGCGATGCAGGGGATCGTTTTTTTAGTGACTAA

Upstream 100 bases:

>100_bases
AATATTAACTTATTTTTTTTAAAATTTATGTTATAATACAACTATTTTAAAAAAATAAAAATTGTTTTGTAAAAAAACAA
TTTTTAAAGGAGAAATTAAT

Downstream 100 bases:

>100_bases
ATATGGCTAATTCAATTTTTTGGCGTTCTAATTTAAATTTTAAATTAACAGTAGCCGGAATTTTACTTTCACTTTCGATT
ATTTTTTTAATTTTTTCGCA

Product: uracil phosphoribosyltransferase

Products: NA

Alternate protein names: UMP pyrophosphorylase; UPRTase [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MEIKVDHPLIDSEIARIRQMTTLKDFRNSIKKISKLLAFPVLSRLETEEFRAKSVLGHEFLGHKIITKLVFIPILRAGFG
MLDSFLELAPYAKVAPIGLKRNSDLSIQTYFESLPQANPNSVAIVLEPILATGNTLIRAIEIILEKGYKKIVIATMLTVQ
VGIDKILERYPQISIFFCQKDPKLNNKGYIIPGIGDAGDRFFSD

Sequences:

>Translated_204_residues
MEIKVDHPLIDSEIARIRQMTTLKDFRNSIKKISKLLAFPVLSRLETEEFRAKSVLGHEFLGHKIITKLVFIPILRAGFG
MLDSFLELAPYAKVAPIGLKRNSDLSIQTYFESLPQANPNSVAIVLEPILATGNTLIRAIEIILEKGYKKIVIATMLTVQ
VGIDKILERYPQISIFFCQKDPKLNNKGYIIPGIGDAGDRFFSD
>Mature_204_residues
MEIKVDHPLIDSEIARIRQMTTLKDFRNSIKKISKLLAFPVLSRLETEEFRAKSVLGHEFLGHKIITKLVFIPILRAGFG
MLDSFLELAPYAKVAPIGLKRNSDLSIQTYFESLPQANPNSVAIVLEPILATGNTLIRAIEIILEKGYKKIVIATMLTVQ
VGIDKILERYPQISIFFCQKDPKLNNKGYIIPGIGDAGDRFFSD

Specific function: Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate [H]

COG id: COG0035

COG function: function code F; Uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPRTase family [H]

Homologues:

Organism=Escherichia coli, GI87082118, Length=203, Percent_Identity=32.0197044334975, Blast_Score=121, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6321920, Length=186, Percent_Identity=26.3440860215054, Blast_Score=81, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573516, Length=138, Percent_Identity=28.9855072463768, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28573514, Length=138, Percent_Identity=28.9855072463768, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28573512, Length=138, Percent_Identity=28.9855072463768, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45550449, Length=138, Percent_Identity=28.9855072463768, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: 2580 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR005765 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 22929; Mature: 22929

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIKVDHPLIDSEIARIRQMTTLKDFRNSIKKISKLLAFPVLSRLETEEFRAKSVLGHEF
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGHKIITKLVFIPILRAGFGMLDSFLELAPYAKVAPIGLKRNSDLSIQTYFESLPQANPN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCC
SVAIVLEPILATGNTLIRAIEIILEKGYKKIVIATMLTVQVGIDKILERYPQISIFFCQK
CEEEEEECHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
DPKLNNKGYIIPGIGDAGDRFFSD
CCCCCCCCEEECCCCCCCHHCCCC
>Mature Secondary Structure
MEIKVDHPLIDSEIARIRQMTTLKDFRNSIKKISKLLAFPVLSRLETEEFRAKSVLGHEF
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGHKIITKLVFIPILRAGFGMLDSFLELAPYAKVAPIGLKRNSDLSIQTYFESLPQANPN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCC
SVAIVLEPILATGNTLIRAIEIILEKGYKKIVIATMLTVQVGIDKILERYPQISIFFCQK
CEEEEEECHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
DPKLNNKGYIIPGIGDAGDRFFSD
CCCCCCCCEEECCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA