BacMap

Definition	Mycoplasma hyopneumoniae J chromosome, complete genome.
Accession	NC_007295
Length	897,405

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The map label for this gene is malK [C]

Identifier: 71893817

GI number: 71893817

Start: 590769

End: 591443

Strand: Reverse

Name: malK [C]

Synonym: MHJ_0466

Alternate gene names: 71893817

Gene position: 591443-590769 (Counterclockwise)

Preceding gene: 71893818

Following gene: 71893816

Centisome position: 65.91

GC content: 26.37

Gene sequence:

>675_bases
ATTCAAAATCAGAAGCAGGGGTTAAAAATGTTAGTTTTAAGGTTAAAAAAAAACCAAATTCATGCATTTATTGGCAAAAA
TGGCGCGGGGAAAACAACAGTAATTAAGTGCATTGTTGATGCTTATCAAAAATTTTCCGGAAAAATTTTAATTAACAATT
TTCTAAATAAGTTACCTGAGGCAAAAAAATTCATCGGTTATGTTCCGGAAAATTCTTTTTTTCCCCGTGAGTTAAATTCT
TATGAGTTTTTATATGAATTTGGCCTTTTATCAAAAATGGAACCAGAACTGGTAAAGAAAAAAATTGACTATTATTTTAA
ATTTTTAAAAATTGAAAATTTAGCAAAATTAAAACCATTTAATTTTTCATCTGGTCAAAAACGCAAAATTATGATAGTCC
AATCTTTGATTCATGATCCAGAATTAATTATTTTTGATGAGCCATTTTCTAATCTTGATCCTTCAGCGCGAAATGAATTC
CGTGCAATTATAAAAATTCTTCAAAAACAAGGTAAAACAATATTTTTGTCAAGTCATAATTTATATGAAATTGATACATT
AATTGATAGTTTGACTCTAATCGACAAAGGTAAGATTTATTATAGTGGTCAAAAAACTGATAGTTTATATAAAATGTATC
AAAAATATTCTCAAAATAGTCGTGAAAGTGAATAA

Upstream 100 bases:

>100_bases
TTCTGCAATTTTATTATTTTTTATCTTTATTATTTATTCAAGAAAGGACTATAAATAATGTCTGATTGGATTTTGGAAGT
AGAAAATCTAACAAAAATTT

Downstream 100 bases:

>100_bases
TGCTAAAAAAAATTTCATTTTTTTTATTAACAGTAACTCCTTTTTTTGGTCTTATTTCTTGTAGTAGTATTTATAAATTT
TATGAATTTATTCCCAAAAA

Product: putative ABC transporter atp-binding protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MQNQKQGLKMLVLRLKKNQIHAFIGKNGAGKTTVIKCIVDAYQKFSGKILINNFLNKLPEAKKFIGYVPENSFFPRELNS
YEFLYEFGLLSKMEPELVKKKIDYYFKFLKIENLAKLKPFNFSSGQKRKIMIVQSLIHDPELIIFDEPFSNLDPSARNEF
RAIIKILQKQGKTIFLSSHNLYEIDTLIDSLTLIDKGKIYYSGQKTDSLYKMYQKYSQNSRESE

Sequences:

>Translated_224_residues
MQNQKQGLKMLVLRLKKNQIHAFIGKNGAGKTTVIKCIVDAYQKFSGKILINNFLNKLPEAKKFIGYVPENSFFPRELNS
YEFLYEFGLLSKMEPELVKKKIDYYFKFLKIENLAKLKPFNFSSGQKRKIMIVQSLIHDPELIIFDEPFSNLDPSARNEF
RAIIKILQKQGKTIFLSSHNLYEIDTLIDSLTLIDKGKIYYSGQKTDSLYKMYQKYSQNSRESE
>Mature_224_residues
MQNQKQGLKMLVLRLKKNQIHAFIGKNGAGKTTVIKCIVDAYQKFSGKILINNFLNKLPEAKKFIGYVPENSFFPRELNS
YEFLYEFGLLSKMEPELVKKKIDYYFKFLKIENLAKLKPFNFSSGQKRKIMIVQSLIHDPELIIFDEPFSNLDPSARNEF
RAIIKILQKQGKTIFLSSHNLYEIDTLIDSLTLIDKGKIYYSGQKTDSLYKMYQKYSQNSRESE

Specific function: This Is One Of The Five Proteins Essential To The Active Binding Protein-Dependent Transport System For Maltose And Maltodextrin. Malk Is The Target For Inducer Exclusion, Mediated By The Unphosphorylated Enzyme III Of The Phosphotransferase System For G

COG id: COG1131

COG function: function code V; ABC-type multidrug transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI45446740, Length=205, Percent_Identity=31.219512195122, Blast_Score=101, Evalue=4e-22,
Organism=Homo sapiens, GI47078218, Length=205, Percent_Identity=31.219512195122, Blast_Score=101, Evalue=4e-22,
Organism=Homo sapiens, GI27477115, Length=202, Percent_Identity=28.7128712871287, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI105990541, Length=191, Percent_Identity=28.2722513089005, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI21536376, Length=208, Percent_Identity=27.8846153846154, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI116734710, Length=216, Percent_Identity=28.2407407407407, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI153792144, Length=208, Percent_Identity=25, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI31657092, Length=208, Percent_Identity=26.4423076923077, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI6005701, Length=191, Percent_Identity=25.130890052356, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI27262624, Length=205, Percent_Identity=24.390243902439, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI27262626, Length=205, Percent_Identity=24.390243902439, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI150417984, Length=197, Percent_Identity=25.3807106598985, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI27881501, Length=187, Percent_Identity=25.668449197861, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI30795238, Length=187, Percent_Identity=25.668449197861, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI11967969, Length=219, Percent_Identity=23.7442922374429, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI62526033, Length=211, Percent_Identity=28.9099526066351, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI27436953, Length=202, Percent_Identity=24.2574257425743, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI215820660, Length=213, Percent_Identity=24.8826291079812, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI20143975, Length=213, Percent_Identity=24.8826291079812, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI46592964, Length=204, Percent_Identity=25, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI46592898, Length=207, Percent_Identity=24.6376811594203, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI46592971, Length=207, Percent_Identity=24.6376811594203, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI46592978, Length=207, Percent_Identity=24.6376811594203, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI255708477, Length=217, Percent_Identity=26.2672811059908, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI46592956, Length=212, Percent_Identity=24.5283018867925, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI46592915, Length=212, Percent_Identity=24.5283018867925, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790467, Length=196, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786319, Length=197, Percent_Identity=29.9492385786802, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788450, Length=199, Percent_Identity=28.1407035175879, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1789593, Length=208, Percent_Identity=25.4807692307692, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87081791, Length=209, Percent_Identity=24.4019138755981, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787370, Length=203, Percent_Identity=25.615763546798, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1788761, Length=204, Percent_Identity=25.4901960784314, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082267, Length=199, Percent_Identity=25.1256281407035, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786398, Length=204, Percent_Identity=24.5098039215686, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1788225, Length=204, Percent_Identity=25.4901960784314, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI48994943, Length=194, Percent_Identity=26.2886597938144, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1787029, Length=201, Percent_Identity=25.3731343283582, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1787164, Length=193, Percent_Identity=26.9430051813472, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1786253, Length=201, Percent_Identity=23.3830845771144, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87081782, Length=195, Percent_Identity=25.1282051282051, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1787547, Length=212, Percent_Identity=24.5283018867925, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788472, Length=227, Percent_Identity=27.3127753303965, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788210, Length=193, Percent_Identity=29.5336787564767, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1789672, Length=198, Percent_Identity=24.7474747474747, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1790525, Length=213, Percent_Identity=30.0469483568075, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790739, Length=202, Percent_Identity=24.7524752475248, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI87081709, Length=202, Percent_Identity=25.2475247524752, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1789032, Length=208, Percent_Identity=25, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787792, Length=221, Percent_Identity=27.1493212669683, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787112, Length=220, Percent_Identity=22.2727272727273, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786563, Length=198, Percent_Identity=24.2424242424242, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786975, Length=216, Percent_Identity=25, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI87082268, Length=202, Percent_Identity=25.2475247524752, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788540, Length=177, Percent_Identity=29.9435028248588, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1787712, Length=211, Percent_Identity=25.1184834123223, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87081834, Length=175, Percent_Identity=23.4285714285714, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790162, Length=232, Percent_Identity=25.4310344827586, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1786872, Length=190, Percent_Identity=25.7894736842105, Blast_Score=60, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17510237, Length=215, Percent_Identity=31.1627906976744, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71983523, Length=196, Percent_Identity=29.5918367346939, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71983516, Length=196, Percent_Identity=29.5918367346939, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71983510, Length=196, Percent_Identity=29.5918367346939, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI115533608, Length=199, Percent_Identity=29.6482412060301, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17565586, Length=204, Percent_Identity=28.4313725490196, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6319856, Length=202, Percent_Identity=29.2079207920792, Blast_Score=69, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24666092, Length=190, Percent_Identity=32.1052631578947, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24643674, Length=201, Percent_Identity=26.865671641791, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI221512771, Length=203, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24650855, Length=189, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24650853, Length=189, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI281362751, Length=189, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24648314, Length=200, Percent_Identity=27, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI85725262, Length=183, Percent_Identity=30.0546448087432, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28574150, Length=190, Percent_Identity=26.3157894736842, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI116007328, Length=190, Percent_Identity=26.3157894736842, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI116007184, Length=218, Percent_Identity=24.3119266055046, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221500365, Length=214, Percent_Identity=24.7663551401869, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28573571, Length=194, Percent_Identity=22.1649484536082, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI28573573, Length=194, Percent_Identity=22.1649484536082, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24582014, Length=190, Percent_Identity=26.8421052631579, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24582012, Length=190, Percent_Identity=26.8421052631579, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24581191, Length=215, Percent_Identity=27.906976744186, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581189, Length=215, Percent_Identity=27.906976744186, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581193, Length=215, Percent_Identity=27.906976744186, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581195, Length=215, Percent_Identity=27.906976744186, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI85724858, Length=197, Percent_Identity=25.3807106598985, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI85724856, Length=197, Percent_Identity=25.3807106598985, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24580547, Length=197, Percent_Identity=25.3807106598985, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24580551, Length=197, Percent_Identity=25.3807106598985, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24580549, Length=197, Percent_Identity=25.3807106598985, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24580545, Length=197, Percent_Identity=25.3807106598985, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI161076684, Length=215, Percent_Identity=27.4418604651163, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581617, Length=215, Percent_Identity=27.4418604651163, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581615, Length=215, Percent_Identity=27.4418604651163, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161076682, Length=215, Percent_Identity=27.4418604651163, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574533, Length=214, Percent_Identity=25.2336448598131, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI85724864, Length=210, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24580555, Length=210, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI85816269, Length=210, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24580553, Length=210, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28574744, Length=195, Percent_Identity=23.5897435897436, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 26165; Mature: 26165

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNQKQGLKMLVLRLKKNQIHAFIGKNGAGKTTVIKCIVDAYQKFSGKILINNFLNKLPE
CCCHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHCCEEHHHHHHHHCCH
AKKFIGYVPENSFFPRELNSYEFLYEFGLLSKMEPELVKKKIDYYFKFLKIENLAKLKPF
HHHHHEECCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
NFSSGQKRKIMIVQSLIHDPELIIFDEPFSNLDPSARNEFRAIIKILQKQGKTIFLSSHN
CCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCC
LYEIDTLIDSLTLIDKGKIYYSGQKTDSLYKMYQKYSQNSRESE
CCHHHHHHHHHHHEECCEEEECCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQNQKQGLKMLVLRLKKNQIHAFIGKNGAGKTTVIKCIVDAYQKFSGKILINNFLNKLPE
CCCHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHCCEEHHHHHHHHCCH
AKKFIGYVPENSFFPRELNSYEFLYEFGLLSKMEPELVKKKIDYYFKFLKIENLAKLKPF
HHHHHEECCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
NFSSGQKRKIMIVQSLIHDPELIIFDEPFSNLDPSARNEFRAIIKILQKQGKTIFLSSHN
CCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCC
LYEIDTLIDSLTLIDKGKIYYSGQKTDSLYKMYQKYSQNSRESE
CCHHHHHHHHHHHEECCEEEECCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]