Click here to switch to the map view.

The map label for this gene is php [C]

Identifier: 71893726

GI number: 71893726

Start: 459953

End: 461005

Strand: Reverse

Name: php [C]

Synonym: MHJ_0373

Alternate gene names: 71893726

Gene position: 461005-459953 (Counterclockwise)

Preceding gene: 71893727

Following gene: 71893725

Centisome position: 51.37

GC content: 35.61

Gene sequence:

>1053_bases
ATGGACAAATTTTCACGAACTGTTCTCGGTGATATTCACCCATCGGAATTAGGTGTTGTTGACTGTCATGATCATTTAAT
TAAAAATTATGGGCCAGAAGCTCACGAACATCCGGATTTTGTAATGTTATCAAATGAGGCTGCAATTGCTGAATCACTTG
AATATGCTTCCCGGGGTGGAAAAACAATAGTGACAATGGATCCCCCAAATGTTGGTCGGGATGTCTATCGAATGTTAGAG
ATTGCCAAAGCTCTTGAAGGAAAAGTGCATATTATTATGGCAACTGGATTTCATAAAGCGGCTTTCTATGATAAAGGCGC
ATCATGACTTGCGCTTGCACCAACAGATGAAATTGTAAAAATGGTTGTTGCTGAAATTACACAGGGAATGGATGAATATA
ATTATTCAGGTCCTGTGGTTAGACGTTCAAAAGCCAAAGCAGGAATTATTAAAGCCGGAACTGGATATGGAGCAATTGAT
CGACTTGAATTAAAATCACTTGAGGTTGCAGCAAGAGCCTCAATTGAAACCGGGGCACCGATTTTGGTTCATACCCAATT
AGGAACAATGGCCTATGAAGCGGCAAAATATTTAATTGATTTTGGTGCAAATCCACGGAAAATTCAGATCTCACATCTTA
ATAAAAACCCTGATAAATATTATTATGCAAAAATAATTAAAGAACTTGGGGTATCTTTATGTTTTGATGGTCCTGATCGG
GTTAAGTATTTTCCTGATACAACTCTTGCTGAAAATATTAAATATCTTGTCGATCTAGGACTAGAAAAACATATTACCTT
ATCACTTGATGCCGGTCGTGTTTTATATCAGCGAAATTATGGAAAACTTAAAGGTAAATGAACTTTTGGACTAACCTATT
TATTCGATCGGTTTATTCCGCTTTTAGAACAAGTTGGAATTAGCAAGGAAACAATTAATAATATTCTTGTTAATAATCCA
GCTGAAATTCTTGCCTTTGATCAGCCAAGAAAATTTGATCCATCAATTCTTCCAGATTATATTATTGAATTAAAAAAATC
CTTTAAAATCTAG

Upstream 100 bases:

>100_bases
TAATTTTAATGTTATAATTAAAATGTTTAAAATAACAAAAAAATAAAAAATTTTTCAAATTAAATTCAAAATTAACGAAA
GGATAAATTTTATTTAAAAA

Downstream 100 bases:

>100_bases
AAGAATTTCGTTTTTTTAACAAAAATTTTTGTTAAAAAACCCTGGTTTTTATACGTTAATCGATCTTTTTAGACTAAATT
TTCGAAAGGAAATATAAATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MDKFSRTVLGDIHPSELGVVDCHDHLIKNYGPEAHEHPDFVMLSNEAAIAESLEYASRGGKTIVTMDPPNVGRDVYRMLE
IAKALEGKVHIIMATGFHKAAFYDKGASWLALAPTDEIVKMVVAEITQGMDEYNYSGPVVRRSKAKAGIIKAGTGYGAID
RLELKSLEVAARASIETGAPILVHTQLGTMAYEAAKYLIDFGANPRKIQISHLNKNPDKYYYAKIIKELGVSLCFDGPDR
VKYFPDTTLAENIKYLVDLGLEKHITLSLDAGRVLYQRNYGKLKGKWTFGLTYLFDRFIPLLEQVGISKETINNILVNNP
AEILAFDQPRKFDPSILPDYIIELKKSFKI

Sequences:

>Translated_350_residues
MDKFSRTVLGDIHPSELGVVDCHDHLIKNYGPEAHEHPDFVMLSNEAAIAESLEYASRGGKTIVTMDPPNVGRDVYRMLE
IAKALEGKVHIIMATGFHKAAFYDKGAS*LALAPTDEIVKMVVAEITQGMDEYNYSGPVVRRSKAKAGIIKAGTGYGAID
RLELKSLEVAARASIETGAPILVHTQLGTMAYEAAKYLIDFGANPRKIQISHLNKNPDKYYYAKIIKELGVSLCFDGPDR
VKYFPDTTLAENIKYLVDLGLEKHITLSLDAGRVLYQRNYGKLKGK*TFGLTYLFDRFIPLLEQVGISKETINNILVNNP
AEILAFDQPRKFDPSILPDYIIELKKSFKI
>Mature_350_residues
MDKFSRTVLGDIHPSELGVVDCHDHLIKNYGPEAHEHPDFVMLSNEAAIAESLEYASRGGKTIVTMDPPNVGRDVYRMLE
IAKALEGKVHIIMATGFHKAAFYDKGAS*LALAPTDEIVKMVVAEITQGMDEYNYSGPVVRRSKAKAGIIKAGTGYGAID
RLELKSLEVAARASIETGAPILVHTQLGTMAYEAAKYLIDFGANPRKIQISHLNKNPDKYYYAKIIKELGVSLCFDGPDR
VKYFPDTTLAENIKYLVDLGLEKHITLSLDAGRVLYQRNYGKLKGK*TFGLTYLFDRFIPLLEQVGISKETINNILVNNP
AEILAFDQPRKFDPSILPDYIIELKKSFKI

Specific function: Its Real Enzymatic Activity Is Not Yet Known. It Was Tested For General Esterase, Aminopeptidase, Sulfatase, Phosphatase, Carbonic Anhydrase, Phosphodiesterase, And Phosphotriesterase Activities With The Following Substrates: P- Nitrophenyl Acetate, L-Ala

COG id: COG1735

COG function: function code R; Predicted metal-dependent hydrolase with the TIM-barrel fold

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphotriesterase family [H]

Homologues:

Organism=Homo sapiens, GI20070186, Length=360, Percent_Identity=23.3333333333333, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI47933341, Length=360, Percent_Identity=23.3333333333333, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1789780, Length=282, Percent_Identity=29.4326241134752, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001559 [H]

Pfam domain/function: PF02126 PTE [H]

EC number: NA

Molecular weight: Translated: 38661; Mature: 38661

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKFSRTVLGDIHPSELGVVDCHDHLIKNYGPEAHEHPDFVMLSNEAAIAESLEYASRGG
CCCHHHHHHCCCCCCCCCEECHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHCCC
KTIVTMDPPNVGRDVYRMLEIAKALEGKVHIIMATGFHKAAFYDKGASLALAPTDEIVKM
CEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCHHHHCCCCCEEEECCHHHHHHH
VVAEITQGMDEYNYSGPVVRRSKAKAGIIKAGTGYGAIDRLELKSLEVAARASIETGAPI
HHHHHHHCHHHCCCCCCEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCE
LVHTQLGTMAYEAAKYLIDFGANPRKIQISHLNKNPDKYYYAKIIKELGVSLCFDGPDRV
EEEECHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCCE
KYFPDTTLAENIKYLVDLGLEKHITLSLDAGRVLYQRNYGKLKGKTFGLTYLFDRFIPLL
EECCCCHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCCCCCCEEHHHHHHHHHHHHH
EQVGISKETINNILVNNPAEILAFDQPRKFDPSILPDYIIELKKSFKI
HHHCCCHHHHHHHHCCCCHHEEEECCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MDKFSRTVLGDIHPSELGVVDCHDHLIKNYGPEAHEHPDFVMLSNEAAIAESLEYASRGG
CCCHHHHHHCCCCCCCCCEECHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHCCC
KTIVTMDPPNVGRDVYRMLEIAKALEGKVHIIMATGFHKAAFYDKGASLALAPTDEIVKM
CEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCHHHHCCCCCEEEECCHHHHHHH
VVAEITQGMDEYNYSGPVVRRSKAKAGIIKAGTGYGAIDRLELKSLEVAARASIETGAPI
HHHHHHHCHHHCCCCCCEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCE
LVHTQLGTMAYEAAKYLIDFGANPRKIQISHLNKNPDKYYYAKIIKELGVSLCFDGPDRV
EEEECHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCCE
KYFPDTTLAENIKYLVDLGLEKHITLSLDAGRVLYQRNYGKLKGKTFGLTYLFDRFIPLL
EECCCCHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCCCCCCEEHHHHHHHHHHHHH
EQVGISKETINNILVNNPAEILAFDQPRKFDPSILPDYIIELKKSFKI
HHHCCCHHHHHHHHCCCCHHEEEECCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]