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The map label for this gene is nuoH

Identifier: 71892260

GI number: 71892260

Start: 601137

End: 602108

Strand: Reverse

Name: nuoH

Synonym: BPEN_503

Alternate gene names: 71892260

Gene position: 602108-601137 (Counterclockwise)

Preceding gene: 71892261

Following gene: 71892259

Centisome position: 76.06

GC content: 33.23

Gene sequence:

>972_bases
ATGTTTGGTTCGTCAGAAATTGTTACGAAACATTGTGTTTCCGAAATTTTTCATGCGGTAATTATTTTGTTAGTGGTAGT
CGCTTGTGGTGCATACATGAGTTTTTTAGAACGCAGATTATTGGCGTTGTTTCAAAATCGTTATGGTCCTAATAGAGTAG
GTTGGCATGGTTCATTACAATTATGCGCTGATTTAATTAAAGTTATGTTCAAGGAGGATTGGATCCCTCCATTTTCTGAT
CGTATTGTATTTGTTTTGGCCCCAGTGATAGCTTTTATTTCATCATTAATGAGTATATTGATTATTCCTTTTACGCCTAC
ATGGATAATATGGGATTGTAATATTGGTATATTATTCTTTCTTATGATGTCAGGATTGACGGTTTATTCAGTGTTGCTTG
CGGGTTGGGCAAGTAACAATAAATATGCTTTAATTGGAGCTGTGCGTGCTGCAGCGCAAACTCTTAGTTATGAGGTGTTT
TTAGGTTTATCTATAATGGGTGTAGTTGCTAAATCTGGATCGTTTAATTTAAAAATTATAGTTGAAGATCAGTTATATCT
GTGGAATGTAATTCCTCAGTTTGTAGGATTTATTACTTTTTTTTTAGCTGGCATGGCTTTGTGTCATAGACATCCATTTG
ATCAACCAGAATCAGAACAAGAGTTGGCAGATGGTTATCATATTGAATATTCCGGTATTAAATTTAGTTTATTTTTTATT
TCTGGATATATCAATATGATTGTCATTGCTTCATTCATTGTAACACTATTTTTTGGGGGGTGGCAAGGACCTTGGTTTCC
TCCTATGATTTTGTTTATTACTAAAACTTTTTTATTGTTGATAGTGTTTATATTGATACGTGCGGCCTTACCACGTCCAC
GTTATGATCAAGTTATGTTGATAGGTTGGAAAATTTGTTTACCAATGACGTTGTTTAATTTATTAAGTACTGCTGTTGTT
ATTTTATTATAA

Upstream 100 bases:

>100_bases
ATTTACCTACAGGCCATATTGGATTACCTTTAGGTTTTCCAGATATTCCTTTATTTTTATCTGGTATGTATGCACAAGAT
GTTCAAGGAGTATTATTGTG

Downstream 100 bases:

>100_bases
TTATTAATATAGGTTAAATATATTATGATGAAGTTAAAAAAGGTTTTTATAGATATTGGTTCTATATTACGTAGTATTTG
GATGATAGGAATGCAAGCAT

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MFGSSEIVTKHCVSEIFHAVIILLVVVACGAYMSFLERRLLALFQNRYGPNRVGWHGSLQLCADLIKVMFKEDWIPPFSD
RIVFVLAPVIAFISSLMSILIIPFTPTWIIWDCNIGILFFLMMSGLTVYSVLLAGWASNNKYALIGAVRAAAQTLSYEVF
LGLSIMGVVAKSGSFNLKIIVEDQLYLWNVIPQFVGFITFFLAGMALCHRHPFDQPESEQELADGYHIEYSGIKFSLFFI
SGYINMIVIASFIVTLFFGGWQGPWFPPMILFITKTFLLLIVFILIRAALPRPRYDQVMLIGWKICLPMTLFNLLSTAVV
ILL

Sequences:

>Translated_323_residues
MFGSSEIVTKHCVSEIFHAVIILLVVVACGAYMSFLERRLLALFQNRYGPNRVGWHGSLQLCADLIKVMFKEDWIPPFSD
RIVFVLAPVIAFISSLMSILIIPFTPTWIIWDCNIGILFFLMMSGLTVYSVLLAGWASNNKYALIGAVRAAAQTLSYEVF
LGLSIMGVVAKSGSFNLKIIVEDQLYLWNVIPQFVGFITFFLAGMALCHRHPFDQPESEQELADGYHIEYSGIKFSLFFI
SGYINMIVIASFIVTLFFGGWQGPWFPPMILFITKTFLLLIVFILIRAALPRPRYDQVMLIGWKICLPMTLFNLLSTAVV
ILL
>Mature_323_residues
MFGSSEIVTKHCVSEIFHAVIILLVVVACGAYMSFLERRLLALFQNRYGPNRVGWHGSLQLCADLIKVMFKEDWIPPFSD
RIVFVLAPVIAFISSLMSILIIPFTPTWIIWDCNIGILFFLMMSGLTVYSVLLAGWASNNKYALIGAVRAAAQTLSYEVF
LGLSIMGVVAKSGSFNLKIIVEDQLYLWNVIPQFVGFITFFLAGMALCHRHPFDQPESEQELADGYHIEYSGIKFSLFFI
SGYINMIVIASFIVTLFFGGWQGPWFPPMILFITKTFLLLIVFILIRAALPRPRYDQVMLIGWKICLPMTLFNLLSTAVV
ILL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family

Homologues:

Organism=Homo sapiens, GI251831107, Length=283, Percent_Identity=41.3427561837456, Blast_Score=196, Evalue=2e-50,
Organism=Escherichia coli, GI1788618, Length=307, Percent_Identity=71.0097719869707, Blast_Score=464, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOH_BLOPB (Q492I2)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277994.1
- STRING:   Q492I2
- GeneID:   3563020
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_503
- eggNOG:   COG1005
- HOGENOM:   HBG727670
- OMA:   MSWLTPE
- ProtClustDB:   PRK06076
- BioCyc:   CBLO291272:BPEN_503-MONOMER
- HAMAP:   MF_01350
- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086
- PANTHER:   PTHR11432

Pfam domain/function: PF00146 NADHdh

EC number: =1.6.99.5

Molecular weight: Translated: 36481; Mature: 36481

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS00667 COMPLEX1_ND1_1; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11b29d88)-; HASH(0x11ab3e5c)-; HASH(0xb548adc)-; HASH(0x1193a688)-; HASH(0x11beb4d8)-; HASH(0x11754d70)-; HASH(0x10e22604)-; HASH(0x10e870f4)-;

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGSSEIVTKHCVSEIFHAVIILLVVVACGAYMSFLERRLLALFQNRYGPNRVGWHGSLQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LCADLIKVMFKEDWIPPFSDRIVFVLAPVIAFISSLMSILIIPFTPTWIIWDCNIGILFF
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHH
LMMSGLTVYSVLLAGWASNNKYALIGAVRAAAQTLSYEVFLGLSIMGVVAKSGSFNLKII
HHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
VEDQLYLWNVIPQFVGFITFFLAGMALCHRHPFDQPESEQELADGYHIEYSGIKFSLFFI
EECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCEEEECCEEEEHHHH
SGYINMIVIASFIVTLFFGGWQGPWFPPMILFITKTFLLLIVFILIRAALPRPRYDQVML
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
IGWKICLPMTLFNLLSTAVVILL
HHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MFGSSEIVTKHCVSEIFHAVIILLVVVACGAYMSFLERRLLALFQNRYGPNRVGWHGSLQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LCADLIKVMFKEDWIPPFSDRIVFVLAPVIAFISSLMSILIIPFTPTWIIWDCNIGILFF
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHH
LMMSGLTVYSVLLAGWASNNKYALIGAVRAAAQTLSYEVFLGLSIMGVVAKSGSFNLKII
HHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
VEDQLYLWNVIPQFVGFITFFLAGMALCHRHPFDQPESEQELADGYHIEYSGIKFSLFFI
EECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCEEEECCEEEEHHHH
SGYINMIVIASFIVTLFFGGWQGPWFPPMILFITKTFLLLIVFILIRAALPRPRYDQVML
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
IGWKICLPMTLFNLLSTAVVILL
HHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA