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The map label for this gene is pgsA

Identifier: 71892191

GI number: 71892191

Start: 504315

End: 504866

Strand: Reverse

Name: pgsA

Synonym: BPEN_427

Alternate gene names: 71892191

Gene position: 504866-504315 (Counterclockwise)

Preceding gene: 71892197

Following gene: 71892188

Centisome position: 63.77

GC content: 35.69

Gene sequence:

>552_bases
ATGGATATTATTAATATACCTACGTATCTTACTTTATTACGTGTTGTCATGGTGCCGTTTTTTACGGTAATGTTTTATTT
ACCTGTAAGGTGGGCGCCGATGATATGTACTATTATGTTTTTTGTTGCGGCTGTTACAGATTGGTTTGATGGGTTTTTGG
CTCGGCGTTGGAAACAAACTACTAGCTTTGGTAAATTTTTAGATCCAGTAGCAGATAAAGTTATGATAGTTGCGGCACTT
GTTTTAATAGCTGAGCATTTTCATACGTGGTGGGTCACATTACCAGCGTCCATTATAATTATTCGTGAAGTGATTATATT
AGCATTGCGTGAATGGGTAGCTGCAATTGGTAGTCGTAACGGAATTGGGGTTTTATGGATTAGCAAAATCAAAACATTTG
TACAAATGTTGGCTTTAACTGCATTACTATGGAGCTCTGATGAATGGATAGTAATTATAGGCATTGTTGCGTTGTATGTT
TCAGTGTTGTTGACATTTTGGTCTATGTGCCTTTATTTATATATTGTGCGTTATGACTTGTTTAATTATTGA

Upstream 100 bases:

>100_bases
ATTCTTTATAAATATAAAGGATGGAGTATGTATTTATAAAGTTATAGCTCTTTTAAGAGCTAACATTTTAATTTTGTTAA
ATTAATTGTTTTTTGTTATT

Downstream 100 bases:

>100_bases
TTTTTATTTATATAGATTATAATTTTAAGGTGAGCATGTAATTGTATTTATTTGAAAAATTGGAATGGCATTGACCGCTA
TCTATATTAATATATATAGG

Product: phosphotidylglycerophosphate synthetase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MDIINIPTYLTLLRVVMVPFFTVMFYLPVRWAPMICTIMFFVAAVTDWFDGFLARRWKQTTSFGKFLDPVADKVMIVAAL
VLIAEHFHTWWVTLPASIIIIREVIILALREWVAAIGSRNGIGVLWISKIKTFVQMLALTALLWSSDEWIVIIGIVALYV
SVLLTFWSMCLYLYIVRYDLFNY

Sequences:

>Translated_183_residues
MDIINIPTYLTLLRVVMVPFFTVMFYLPVRWAPMICTIMFFVAAVTDWFDGFLARRWKQTTSFGKFLDPVADKVMIVAAL
VLIAEHFHTWWVTLPASIIIIREVIILALREWVAAIGSRNGIGVLWISKIKTFVQMLALTALLWSSDEWIVIIGIVALYV
SVLLTFWSMCLYLYIVRYDLFNY
>Mature_183_residues
MDIINIPTYLTLLRVVMVPFFTVMFYLPVRWAPMICTIMFFVAAVTDWFDGFLARRWKQTTSFGKFLDPVADKVMIVAAL
VLIAEHFHTWWVTLPASIIIIREVIILALREWVAAIGSRNGIGVLWISKIKTFVQMLALTALLWSSDEWIVIIGIVALYV
SVLLTFWSMCLYLYIVRYDLFNY

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family

Homologues:

Organism=Escherichia coli, GI1788220, Length=178, Percent_Identity=57.3033707865169, Blast_Score=220, Evalue=4e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PGSA_BLOPB (Q492P7)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277924.1
- STRING:   Q492P7
- GeneID:   3562737
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_427
- eggNOG:   COG0558
- HOGENOM:   HBG686655
- OMA:   WSYMAAS
- BioCyc:   CBLO291272:BPEN_427-MONOMER
- HAMAP:   MF_01437
- InterPro:   IPR000462
- InterPro:   IPR004570
- PIRSF:   PIRSF000847
- TIGRFAMs:   TIGR00560

Pfam domain/function: PF01066 CDP-OH_P_transf

EC number: =2.7.8.5

Molecular weight: Translated: 21239; Mature: 21239

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10db9d18)-; HASH(0x10d6daf0)-; HASH(0x118ea168)-; HASH(0x10c8c044)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIINIPTYLTLLRVVMVPFFTVMFYLPVRWAPMICTIMFFVAAVTDWFDGFLARRWKQT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSFGKFLDPVADKVMIVAALVLIAEHFHTWWVTLPASIIIIREVIILALREWVAAIGSRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GIGVLWISKIKTFVQMLALTALLWSSDEWIVIIGIVALYVSVLLTFWSMCLYLYIVRYDL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNY
HCH
>Mature Secondary Structure
MDIINIPTYLTLLRVVMVPFFTVMFYLPVRWAPMICTIMFFVAAVTDWFDGFLARRWKQT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSFGKFLDPVADKVMIVAALVLIAEHFHTWWVTLPASIIIIREVIILALREWVAAIGSRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GIGVLWISKIKTFVQMLALTALLWSSDEWIVIIGIVALYVSVLLTFWSMCLYLYIVRYDL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNY
HCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA