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The map label for this gene is lolC [H]

Identifier: 71892175

GI number: 71892175

Start: 484541

End: 485746

Strand: Reverse

Name: lolC [H]

Synonym: BPEN_408

Alternate gene names: 71892175

Gene position: 485746-484541 (Counterclockwise)

Preceding gene: 71892176

Following gene: 71892174

Centisome position: 61.36

GC content: 30.51

Gene sequence:

>1206_bases
ATGCATCGATCAACTATATTGTTTATTGCGCTACGTTATATTTCAGGAAAATCGATAGATCAATTTGGTCGATATATTTA
TTGGTTTTCTAGTTTTGCTATTATGATAGGTGTGATGTCTACGATAACTGTGTTATCAGTCATGAACGGTTTTGAGCGTG
AGTTAAAACAAAATCTTCTTAATTTCATACCTCATGCGTTACTCACTACCTCCAAAGGATACGTACATGTTAGAGATAAA
CCAAATTTAGTATTAGATCAACTACATAATATAACACACGAGGAACCATTGGTCATATCCGATGTAATATTACAAAGTTC
CAATAAAATTTCGTTTGGAGTAATGTTAGGGATCAATCCAGATTGTTTTGAACCGTTGTGTGATTATTTGGTAAATAAAC
ATGAAAATCAATTGGTTTTAGGAAAATATTATATAATTCTTGGTTCAGAATTAGCAAAAAAACTTGAAGCACATATAAAT
GATCAAATTCGTTTGATTATTCCTTCTGTTATGCAGATCACTCCTATTGGCTATATCCCCAGCCAACGATTGTTTACGGT
ATTAGATATTTTTATTACTAACAGTGAAGTTGATTCTTATCAAGTATTGGTTCATCAATCAGATGCTGCTGCGTTAATGC
ATTATCCATTACAATGCGTTACTGGGTGGCGTTTATGGTTACATGAACCATTTTTGCTCAGCAACTATACTCAACAATTG
CGATTACATACAGATTGGATTTGGAAGGATTGGAGAGAATACAAAGGGTCTTTATTTCAAGCGATGAAAATAGAAAAAAA
TATAATGTCTTTGTTGTTAGGTTTAATTATAATAGCAGCAGGTTTTAACATTGTTTCTTTTTTAGTATTATTAATATTGG
AAAAACAAATAGAAATTGCAATACTCAAAACATATGGTTTCACTCGCCGACAGATTATTTTACTTTTTATGGTTCAAGGA
GTTACTAATGGTTTTTTTGGTATTATATTGGGAACGATATTGGGAGTATTGTTATCTCATAAGTTAAATAAAATATTATT
ATTTTTAAAAATATTTCCAGATACTATATTTTTACCTATAGAAATAAAATATTCTCAAATATTAAGTATCATATTCATGA
CGTTTATTATGATTTTATTGGCTACATTCTACCCATCGTGGCGAGCAGCTTCCTTTCATCCTGCAAAAATTTTACGTTAT
GGCTAA

Upstream 100 bases:

>100_bases
TCGTATGCATATGTGCATATAATTATATATTTCATATAATATAAAATATATGATTGTGTATTATTTTTTTATATTTATGA
GGTAACTTAAACAAATATTG

Downstream 100 bases:

>100_bases
TATTCCATTGTTGCAATGTATTCAGTTAACAAAATATTATCAACGTGCTAATTTCTTAATTAAAGTGTTGAATTGCATTA
CTCTAAGTATACAATCTAAC

Product: outer membrane lipoproteins ABC transporter membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MHRSTILFIALRYISGKSIDQFGRYIYWFSSFAIMIGVMSTITVLSVMNGFERELKQNLLNFIPHALLTTSKGYVHVRDK
PNLVLDQLHNITHEEPLVISDVILQSSNKISFGVMLGINPDCFEPLCDYLVNKHENQLVLGKYYIILGSELAKKLEAHIN
DQIRLIIPSVMQITPIGYIPSQRLFTVLDIFITNSEVDSYQVLVHQSDAAALMHYPLQCVTGWRLWLHEPFLLSNYTQQL
RLHTDWIWKDWREYKGSLFQAMKIEKNIMSLLLGLIIIAAGFNIVSFLVLLILEKQIEIAILKTYGFTRRQIILLFMVQG
VTNGFFGIILGTILGVLLSHKLNKILLFLKIFPDTIFLPIEIKYSQILSIIFMTFIMILLATFYPSWRAASFHPAKILRY
G

Sequences:

>Translated_401_residues
MHRSTILFIALRYISGKSIDQFGRYIYWFSSFAIMIGVMSTITVLSVMNGFERELKQNLLNFIPHALLTTSKGYVHVRDK
PNLVLDQLHNITHEEPLVISDVILQSSNKISFGVMLGINPDCFEPLCDYLVNKHENQLVLGKYYIILGSELAKKLEAHIN
DQIRLIIPSVMQITPIGYIPSQRLFTVLDIFITNSEVDSYQVLVHQSDAAALMHYPLQCVTGWRLWLHEPFLLSNYTQQL
RLHTDWIWKDWREYKGSLFQAMKIEKNIMSLLLGLIIIAAGFNIVSFLVLLILEKQIEIAILKTYGFTRRQIILLFMVQG
VTNGFFGIILGTILGVLLSHKLNKILLFLKIFPDTIFLPIEIKYSQILSIIFMTFIMILLATFYPSWRAASFHPAKILRY
G
>Mature_401_residues
MHRSTILFIALRYISGKSIDQFGRYIYWFSSFAIMIGVMSTITVLSVMNGFERELKQNLLNFIPHALLTTSKGYVHVRDK
PNLVLDQLHNITHEEPLVISDVILQSSNKISFGVMLGINPDCFEPLCDYLVNKHENQLVLGKYYIILGSELAKKLEAHIN
DQIRLIIPSVMQITPIGYIPSQRLFTVLDIFITNSEVDSYQVLVHQSDAAALMHYPLQCVTGWRLWLHEPFLLSNYTQQL
RLHTDWIWKDWREYKGSLFQAMKIEKNIMSLLLGLIIIAAGFNIVSFLVLLILEKQIEIAILKTYGFTRRQIILLFMVQG
VTNGFFGIILGTILGVLLSHKLNKILLFLKIFPDTIFLPIEIKYSQILSIIFMTFIMILLATFYPSWRAASFHPAKILRY
G

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=400, Percent_Identity=47, Blast_Score=380, Evalue=1e-107,
Organism=Escherichia coli, GI1787362, Length=422, Percent_Identity=25.5924170616114, Blast_Score=104, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46190; Mature: 46190

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRSTILFIALRYISGKSIDQFGRYIYWFSSFAIMIGVMSTITVLSVMNGFERELKQNLL
CCCCCEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NFIPHALLTTSKGYVHVRDKPNLVLDQLHNITHEEPLVISDVILQSSNKISFGVMLGINP
HHCCHHHHCCCCCEEEECCCCCHHHHHHHCCCCCCCEEHHHHHHCCCCCEEEEEEECCCH
DCFEPLCDYLVNKHENQLVLGKYYIILGSELAKKLEAHINDQIRLIIPSVMQITPIGYIP
HHHHHHHHHHHCCCCCEEEEEEEEEEECHHHHHHHHHHCCCCEEEEECHHHHCCCCCCCC
SQRLFTVLDIFITNSEVDSYQVLVHQSDAAALMHYPLQCVTGWRLWLHEPFLLSNYTQQL
CHHHHHHHHHHEECCCCCCEEEEEECCCHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHH
RLHTDWIWKDWREYKGSLFQAMKIEKNIMSLLLGLIIIAAGFNIVSFLVLLILEKQIEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
ILKTYGFTRRQIILLFMVQGVTNGFFGIILGTILGVLLSHKLNKILLFLKIFPDTIFLPI
EEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEE
EIKYSQILSIIFMTFIMILLATFYPSWRAASFHPAKILRYG
EECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MHRSTILFIALRYISGKSIDQFGRYIYWFSSFAIMIGVMSTITVLSVMNGFERELKQNLL
CCCCCEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NFIPHALLTTSKGYVHVRDKPNLVLDQLHNITHEEPLVISDVILQSSNKISFGVMLGINP
HHCCHHHHCCCCCEEEECCCCCHHHHHHHCCCCCCCEEHHHHHHCCCCCEEEEEEECCCH
DCFEPLCDYLVNKHENQLVLGKYYIILGSELAKKLEAHINDQIRLIIPSVMQITPIGYIP
HHHHHHHHHHHCCCCCEEEEEEEEEEECHHHHHHHHHHCCCCEEEEECHHHHCCCCCCCC
SQRLFTVLDIFITNSEVDSYQVLVHQSDAAALMHYPLQCVTGWRLWLHEPFLLSNYTQQL
CHHHHHHHHHHEECCCCCCEEEEEECCCHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHH
RLHTDWIWKDWREYKGSLFQAMKIEKNIMSLLLGLIIIAAGFNIVSFLVLLILEKQIEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
ILKTYGFTRRQIILLFMVQGVTNGFFGIILGTILGVLLSHKLNKILLFLKIFPDTIFLPI
EEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEE
EIKYSQILSIIFMTFIMILLATFYPSWRAASFHPAKILRYG
EECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]