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The map label for this gene is lolE [H]

Identifier: 71892173

GI number: 71892173

Start: 482601

End: 483836

Strand: Reverse

Name: lolE [H]

Synonym: BPEN_406

Alternate gene names: 71892173

Gene position: 483836-482601 (Counterclockwise)

Preceding gene: 71892174

Following gene: 71892170

Centisome position: 61.12

GC content: 26.78

Gene sequence:

>1236_bases
ATGATGTTGTCTTTGAAAATTGCATTAAAATTTCATCGAGGTTCGAGTAGTAATATTTTAATGTCCTTAATGTCTTTGAT
TTCTGTTATTGGTATTACTATAGGCATATCTATATCTATAATTGCATTAAGCACAATGAATGGTTTTAAATATGAATTAA
GTAATCGTATTTTATCAGTTATTCCGCATGGAGAAATTGAACCAATAAGAGCGCCATTCATTAATTGGCAAACAGTTTTA
GAGTGTATTCGTAAAATACCAGATATTAGTTATGTGAATCCTTATATTAATTTTTATGGCGTTGTTGAATATAATAATAA
ATGGCATGTAGTTTATGTCAGAAGTGTAGATTTAAAGGAAAAAATAAATGAAAACGCATTAATGAATTTTATAGAAAAAG
ATTCTTGGAAATATTTTTGCGAAAATGTAGAAAAAATTATTTTAGGGAAAGGCATATCAGAAGATTTAGGAATTAAAGTG
GGTGATTGGATTACCGTTTTGACTGCTCATGATTTTCGTTCGAACAATAAATTATTGTCATCCAAAAAAATTCGTTTACA
AGTAGCTGGAATATTAAATTTAAATAGTCAATTAGACTGCAATATTGCTATAATGTCTTTATCAGACGCGCAACATTATT
ATGATGAAACGTCAGATGTTTCAGGAATAGCTATTAAGGTTAACAATATTTTTTCTGTTAATAAAACACTATATAAAATT
CAAAGAATGTTTAATCATCAGGTTTTTGCGCGAAGTTGGATGGATACTTATGGGTATATTTATCAAGATATTCAAATGGT
TCGCATAATTATATATTTATCAATGATATTAATTATAGGTATTTCTTGTTTTAATGTAGTTGCTGCATTGATTTTATCCA
TAAAAGACAAAAATTATGATATTGCGATAATTCGTGCATTGGGGGCTAAAAATATTTTAATTCAATATATATTTTTTTGG
TATGGGTTAATTATTTATATAATTTCTAGTATTATAGGAACTGGACTGGGTATTTTTATAGCTTTTAATTTAACGAGTTT
AATTACGATATGTAATGATTTATTGGAAAGTAAAATTTTATCAGAAGGAACTTATTTTATTAATTTTTTACCCGTTAAGC
TAAACGAATGGGACATATTGTTGGTATTAAGCACAACATTATTACTAGGTTCATTAACTAGTTGGTATGCAGCGTCAAAA
ATAAGGCAGGTTAATTTATCTAAAATCTTAAAATAG

Upstream 100 bases:

>100_bases
CATGATTTAGATTTTGCTAAAAAATGCCATAAAATATTAATGATATCTAATGGTAAAATAAAATTGAGTCAGAATGATTC
GTTTAGGTAATTGTTTATAA

Downstream 100 bases:

>100_bases
CATGATTATGATTTTTATTAGAGTATTATAATGGTGCTTTGAGTAGATAAATTGGTTAAATCACATAATCGGATTTTTTA
ATAAAATATCAAATTAATAC

Product: outer membrane lipoproteins ABC transporter membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MMLSLKIALKFHRGSSSNILMSLMSLISVIGITIGISISIIALSTMNGFKYELSNRILSVIPHGEIEPIRAPFINWQTVL
ECIRKIPDISYVNPYINFYGVVEYNNKWHVVYVRSVDLKEKINENALMNFIEKDSWKYFCENVEKIILGKGISEDLGIKV
GDWITVLTAHDFRSNNKLLSSKKIRLQVAGILNLNSQLDCNIAIMSLSDAQHYYDETSDVSGIAIKVNNIFSVNKTLYKI
QRMFNHQVFARSWMDTYGYIYQDIQMVRIIIYLSMILIIGISCFNVVAALILSIKDKNYDIAIIRALGAKNILIQYIFFW
YGLIIYIISSIIGTGLGIFIAFNLTSLITICNDLLESKILSEGTYFINFLPVKLNEWDILLVLSTTLLLGSLTSWYAASK
IRQVNLSKILK

Sequences:

>Translated_411_residues
MMLSLKIALKFHRGSSSNILMSLMSLISVIGITIGISISIIALSTMNGFKYELSNRILSVIPHGEIEPIRAPFINWQTVL
ECIRKIPDISYVNPYINFYGVVEYNNKWHVVYVRSVDLKEKINENALMNFIEKDSWKYFCENVEKIILGKGISEDLGIKV
GDWITVLTAHDFRSNNKLLSSKKIRLQVAGILNLNSQLDCNIAIMSLSDAQHYYDETSDVSGIAIKVNNIFSVNKTLYKI
QRMFNHQVFARSWMDTYGYIYQDIQMVRIIIYLSMILIIGISCFNVVAALILSIKDKNYDIAIIRALGAKNILIQYIFFW
YGLIIYIISSIIGTGLGIFIAFNLTSLITICNDLLESKILSEGTYFINFLPVKLNEWDILLVLSTTLLLGSLTSWYAASK
IRQVNLSKILK
>Mature_411_residues
MMLSLKIALKFHRGSSSNILMSLMSLISVIGITIGISISIIALSTMNGFKYELSNRILSVIPHGEIEPIRAPFINWQTVL
ECIRKIPDISYVNPYINFYGVVEYNNKWHVVYVRSVDLKEKINENALMNFIEKDSWKYFCENVEKIILGKGISEDLGIKV
GDWITVLTAHDFRSNNKLLSSKKIRLQVAGILNLNSQLDCNIAIMSLSDAQHYYDETSDVSGIAIKVNNIFSVNKTLYKI
QRMFNHQVFARSWMDTYGYIYQDIQMVRIIIYLSMILIIGISCFNVVAALILSIKDKNYDIAIIRALGAKNILIQYIFFW
YGLIIYIISSIIGTGLGIFIAFNLTSLITICNDLLESKILSEGTYFINFLPVKLNEWDILLVLSTTLLLGSLTSWYAASK
IRQVNLSKILK

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=410, Percent_Identity=43.1707317073171, Blast_Score=361, Evalue=1e-101,
Organism=Escherichia coli, GI1787360, Length=333, Percent_Identity=24.6246246246246, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925
- InterPro:   IPR011926 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46770; Mature: 46770

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLSLKIALKFHRGSSSNILMSLMSLISVIGITIGISISIIALSTMNGFKYELSNRILSV
CEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHCHHEEE
IPHGEIEPIRAPFINWQTVLECIRKIPDISYVNPYINFYGVVEYNNKWHVVYVRSVDLKE
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEECCCEEEEEEEEECCEEEEEEEEECCHHH
KINENALMNFIEKDSWKYFCENVEKIILGKGISEDLGIKVGDWITVLTAHDFRSNNKLLS
HHCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHCCEEECCEEEEEEEECCCCCCCEEC
SKKIRLQVAGILNLNSQLDCNIAIMSLSDAQHYYDETSDVSGIAIKVNNIFSVNKTLYKI
CCEEEEEEEEEEECCCCCCCEEEEEEECCCHHHHCCCCCCCEEEEEEECEEEHHHHHHHH
QRMFNHQVFARSWMDTYGYIYQDIQMVRIIIYLSMILIIGISCFNVVAALILSIKDKNYD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IAIIRALGAKNILIQYIFFWYGLIIYIISSIIGTGLGIFIAFNLTSLITICNDLLESKIL
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
SEGTYFINFLPVKLNEWDILLVLSTTLLLGSLTSWYAASKIRQVNLSKILK
CCCCEEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MMLSLKIALKFHRGSSSNILMSLMSLISVIGITIGISISIIALSTMNGFKYELSNRILSV
CEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHCHHEEE
IPHGEIEPIRAPFINWQTVLECIRKIPDISYVNPYINFYGVVEYNNKWHVVYVRSVDLKE
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEECCCEEEEEEEEECCEEEEEEEEECCHHH
KINENALMNFIEKDSWKYFCENVEKIILGKGISEDLGIKVGDWITVLTAHDFRSNNKLLS
HHCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHCCEEECCEEEEEEEECCCCCCCEEC
SKKIRLQVAGILNLNSQLDCNIAIMSLSDAQHYYDETSDVSGIAIKVNNIFSVNKTLYKI
CCEEEEEEEEEEECCCCCCCEEEEEEECCCHHHHCCCCCCCEEEEEEECEEEHHHHHHHH
QRMFNHQVFARSWMDTYGYIYQDIQMVRIIIYLSMILIIGISCFNVVAALILSIKDKNYD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IAIIRALGAKNILIQYIFFWYGLIIYIISSIIGTGLGIFIAFNLTSLITICNDLLESKIL
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
SEGTYFINFLPVKLNEWDILLVLSTTLLLGSLTSWYAASKIRQVNLSKILK
CCCCEEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10783239 [H]