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The map label for this gene is trxB [H]

Identifier: 71892165

GI number: 71892165

Start: 471064

End: 472020

Strand: Direct

Name: trxB [H]

Synonym: BPEN_398

Alternate gene names: 71892165

Gene position: 471064-472020 (Clockwise)

Preceding gene: 71892152

Following gene: 71892166

Centisome position: 59.5

GC content: 33.86

Gene sequence:

>957_bases
ATGATGATAAAAAAATATTGCAAACTACTCATATTAGGAGCAGGACCCGCCGGATATACCGCAGCTATTTATGCTGCACG
AGCTAATTTAAATCCTGTATTAGTCACTGGATTAGAAATAGGAGGTCAATTAAATACTACTACAGATATAGAGAATTGGC
CTGGAGATCCAAAAAATCTTACTGGACCTACATTAATGAATCGTATGAATACGCACGCTGTTTCTTTACACACAGAAATT
ATCTCTGATCACATATTTAAAGTAAATTTTAAACAATACCCTTTTTGTTTATATGGTAATACACATGAATATACATGTCA
CGCTTTAATCATAAGTACAGGAGGATATGCTCGCAGTCTTGGTATACCTTCTGAAGAAAAATATAAAGGAAAGGGAGTAT
CTTCGTGTGCTACTTGTGATGGATTTTTTTTTAATAAACAAATTGTTGCAGTTATTGGAGGCGGTAATACAGCGATAGAA
GAAAGTTTATATTTATCTAATATTGCTTCTAAGGTTCATTTGATTCACCGTCGTTCTACATTTAGCGCAGAAAAAATATT
AATTAATAGACTTATGAATAAAGTACACAGCGGTAATGTTGTTTTGCATACTAATCATATCGTTAAAGAAATATTAGGTA
ATGGTACAGATGTTACCGGTTTATGTATGACAGACCTAAAACAACACAAGGAACACATAATAAATCTTCAAGGTATATTT
ATTGCCATTGGATATAATCCAAACACTTCTATATTTAATGATCAACTTGTATTAAACAATGGATACATTTGTGTGCATTC
CGGTATGAATGGCAACGCAACTGCCACCTCTATTCCAGGTATATTTGCAGCAGGAGACGTTATGGATCACAGCTATCGTC
AAGCAATTACTGCAGCTGGATCAGGTTGTATGGCTGCAATAGACGCTGAACGTTATTTATCTACTATTATGTATTAA

Upstream 100 bases:

>100_bases
AAATTACAATATTGCATCTGTTTTCTATTAATATTACATACCAAAAAATATAATGCTTACTACAATATACTTAATCAGCA
TATAAGGAGATACAATTATT

Downstream 100 bases:

>100_bases
TACAACAAAAAATAAAACAAAATTCAAATAAAACTATCTATTAATTTTTAAATAAAATATATAATTATTCGTACTTACAA
AATCTAAAAATAAAAATTAA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MMIKKYCKLLILGAGPAGYTAAIYAARANLNPVLVTGLEIGGQLNTTTDIENWPGDPKNLTGPTLMNRMNTHAVSLHTEI
ISDHIFKVNFKQYPFCLYGNTHEYTCHALIISTGGYARSLGIPSEEKYKGKGVSSCATCDGFFFNKQIVAVIGGGNTAIE
ESLYLSNIASKVHLIHRRSTFSAEKILINRLMNKVHSGNVVLHTNHIVKEILGNGTDVTGLCMTDLKQHKEHIINLQGIF
IAIGYNPNTSIFNDQLVLNNGYICVHSGMNGNATATSIPGIFAAGDVMDHSYRQAITAAGSGCMAAIDAERYLSTIMY

Sequences:

>Translated_318_residues
MMIKKYCKLLILGAGPAGYTAAIYAARANLNPVLVTGLEIGGQLNTTTDIENWPGDPKNLTGPTLMNRMNTHAVSLHTEI
ISDHIFKVNFKQYPFCLYGNTHEYTCHALIISTGGYARSLGIPSEEKYKGKGVSSCATCDGFFFNKQIVAVIGGGNTAIE
ESLYLSNIASKVHLIHRRSTFSAEKILINRLMNKVHSGNVVLHTNHIVKEILGNGTDVTGLCMTDLKQHKEHIINLQGIF
IAIGYNPNTSIFNDQLVLNNGYICVHSGMNGNATATSIPGIFAAGDVMDHSYRQAITAAGSGCMAAIDAERYLSTIMY
>Mature_318_residues
MMIKKYCKLLILGAGPAGYTAAIYAARANLNPVLVTGLEIGGQLNTTTDIENWPGDPKNLTGPTLMNRMNTHAVSLHTEI
ISDHIFKVNFKQYPFCLYGNTHEYTCHALIISTGGYARSLGIPSEEKYKGKGVSSCATCDGFFFNKQIVAVIGGGNTAIE
ESLYLSNIASKVHLIHRRSTFSAEKILINRLMNKVHSGNVVLHTNHIVKEILGNGTDVTGLCMTDLKQHKEHIINLQGIF
IAIGYNPNTSIFNDQLVLNNGYICVHSGMNGNATATSIPGIFAAGDVMDHSYRQAITAAGSGCMAAIDAERYLSTIMY

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=316, Percent_Identity=65.8227848101266, Blast_Score=438, Evalue=1e-124,
Organism=Escherichia coli, GI87081763, Length=300, Percent_Identity=32, Blast_Score=139, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6321898, Length=319, Percent_Identity=42.0062695924765, Blast_Score=244, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6320560, Length=321, Percent_Identity=41.4330218068536, Blast_Score=243, Evalue=3e-65,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34489; Mature: 34489

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIKKYCKLLILGAGPAGYTAAIYAARANLNPVLVTGLEIGGQLNTTTDIENWPGDPKNL
CCHHHEEEEEEEECCCCCCEEEEEEEECCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCC
TGPTLMNRMNTHAVSLHTEIISDHIFKVNFKQYPFCLYGNTHEYTCHALIISTGGYARSL
CCHHHHHHCCCEEEEEHHHHHHCCEEEEECCCCCEEEECCCCCEEEEEEEEECCCCEEEC
GIPSEEKYKGKGVSSCATCDGFFFNKQIVAVIGGGNTAIEESLYLSNIASKVHLIHRRST
CCCCCHHCCCCCCCCHHCCCCEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHEEECCCC
FSAEKILINRLMNKVHSGNVVLHTNHIVKEILGNGTDVTGLCMTDLKQHKEHIINLQGIF
CCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCCEEHHHHHHHHHHHHHEEEEEEEE
IAIGYNPNTSIFNDQLVLNNGYICVHSGMNGNATATSIPGIFAAGDVMDHSYRQAITAAG
EEEEECCCCCEECCEEEEECCEEEEECCCCCCCCEECCCCEEEECHHHHHHHHHHHHHCC
SGCMAAIDAERYLSTIMY
CCCEEEECHHHHHHHHCC
>Mature Secondary Structure
MMIKKYCKLLILGAGPAGYTAAIYAARANLNPVLVTGLEIGGQLNTTTDIENWPGDPKNL
CCHHHEEEEEEEECCCCCCEEEEEEEECCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCC
TGPTLMNRMNTHAVSLHTEIISDHIFKVNFKQYPFCLYGNTHEYTCHALIISTGGYARSL
CCHHHHHHCCCEEEEEHHHHHHCCEEEEECCCCCEEEECCCCCEEEEEEEEECCCCEEEC
GIPSEEKYKGKGVSSCATCDGFFFNKQIVAVIGGGNTAIEESLYLSNIASKVHLIHRRST
CCCCCHHCCCCCCCCHHCCCCEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHEEECCCC
FSAEKILINRLMNKVHSGNVVLHTNHIVKEILGNGTDVTGLCMTDLKQHKEHIINLQGIF
CCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCCEEHHHHHHHHHHHHHEEEEEEEE
IAIGYNPNTSIFNDQLVLNNGYICVHSGMNGNATATSIPGIFAAGDVMDHSYRQAITAAG
EEEEECCCCCEECCEEEEECCEEEEECCCCCCCCEECCCCEEEECHHHHHHHHHHHHHCC
SGCMAAIDAERYLSTIMY
CCCEEEECHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]